Deep brain stimulation for Parkinson's disease and other movement disorders.
Identifieur interne : 000881 ( PubMed/Corpus ); précédent : 000880; suivant : 000882Deep brain stimulation for Parkinson's disease and other movement disorders.
Auteurs : Suneil K. Kalia ; Tejas Sankar ; Andres M. LozanoSource :
- Current opinion in neurology [ 1473-6551 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- methods : Deep Brain Stimulation.
- physiology : Thalamus.
- therapy : Movement Disorders, Parkinson Disease.
- Humans.
Abstract
Deep brain stimulation (DBS) is now widely used in the treatment of Parkinson's disease, tremor, and dystonia. This review examines recent developments in the application of DBS to the management of movement disorders.
DOI: 10.1097/WCO.0b013e3283632d08
PubMed: 23817213
Links to Exploration step
pubmed:23817213Le document en format XML
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<author><name sortKey="Kalia, Suneil K" sort="Kalia, Suneil K" uniqKey="Kalia S" first="Suneil K" last="Kalia">Suneil K. Kalia</name>
<affiliation><nlm:affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
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<author><name sortKey="Sankar, Tejas" sort="Sankar, Tejas" uniqKey="Sankar T" first="Tejas" last="Sankar">Tejas Sankar</name>
</author>
<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Deep brain stimulation for Parkinson's disease and other movement disorders.</title>
<author><name sortKey="Kalia, Suneil K" sort="Kalia, Suneil K" uniqKey="Kalia S" first="Suneil K" last="Kalia">Suneil K. Kalia</name>
<affiliation><nlm:affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
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<author><name sortKey="Sankar, Tejas" sort="Sankar, Tejas" uniqKey="Sankar T" first="Tejas" last="Sankar">Tejas Sankar</name>
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<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
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<series><title level="j">Current opinion in neurology</title>
<idno type="eISSN">1473-6551</idno>
<imprint><date when="2013" type="published">2013</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Deep Brain Stimulation (methods)</term>
<term>Humans</term>
<term>Movement Disorders (therapy)</term>
<term>Parkinson Disease (therapy)</term>
<term>Thalamus (physiology)</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Thalamus</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Movement Disorders</term>
<term>Parkinson Disease</term>
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<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
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<front><div type="abstract" xml:lang="en">Deep brain stimulation (DBS) is now widely used in the treatment of Parkinson's disease, tremor, and dystonia. This review examines recent developments in the application of DBS to the management of movement disorders.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23817213</PMID>
<DateCreated><Year>2013</Year>
<Month>07</Month>
<Day>04</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>02</Month>
<Day>11</Day>
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<DateRevised><Year>2013</Year>
<Month>07</Month>
<Day>04</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1473-6551</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>26</Volume>
<Issue>4</Issue>
<PubDate><Year>2013</Year>
<Month>Aug</Month>
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<Title>Current opinion in neurology</Title>
<ISOAbbreviation>Curr. Opin. Neurol.</ISOAbbreviation>
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<ArticleTitle>Deep brain stimulation for Parkinson's disease and other movement disorders.</ArticleTitle>
<Pagination><MedlinePgn>374-80</MedlinePgn>
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<Abstract><AbstractText Label="PURPOSE OF REVIEW" NlmCategory="OBJECTIVE">Deep brain stimulation (DBS) is now widely used in the treatment of Parkinson's disease, tremor, and dystonia. This review examines recent developments in the application of DBS to the management of movement disorders.</AbstractText>
<AbstractText Label="RECENT FINDINGS" NlmCategory="RESULTS">In Parkinson's disease, recent work has demonstrated that early DBS may have a significant benefit on quality of life and motor symptoms while permitting a decrease in levodopa equivalent dosage. Thalamic DBS continues to be a well established target for the treatment of tremor, although recent work suggests that alternative targets such as the posterior subthalamic area may be similarly efficacious. The treatment of primary dystonia with DBS has been established in multiple recent trials, demonstrating prolonged symptomatic benefit.</AbstractText>
<AbstractText Label="SUMMARY" NlmCategory="CONCLUSIONS">DBS is now an established symptomatic treatment modality for Parkinson's disease and other movement disorders. Future work will undoubtedly involve establishing new indications and targets in the treatment of movement disorders with further refinements to existing technology. Ultimately, these methods combined with biologically based therapies may catalyze a shift from symptomatic treatment to actually modifying the natural history of neurodegenerative diseases such as Parkinson's disease.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kalia</LastName>
<ForeName>Suneil K</ForeName>
<Initials>SK</Initials>
<AffiliationInfo><Affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Sankar</LastName>
<ForeName>Tejas</ForeName>
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<Author ValidYN="Y"><LastName>Lozano</LastName>
<ForeName>Andres M</ForeName>
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<MeshHeading><DescriptorName UI="D009069" MajorTopicYN="N">Movement Disorders</DescriptorName>
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<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
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