Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.
Identifieur interne : 000026 ( PubMed/Corpus ); précédent : 000025; suivant : 000027Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.
Auteurs : Naomi P. Visanji ; Grace S. Bhudhikanok ; Tiago A. Mestre ; Taneera Ghate ; Kaviraj Udupa ; Amaal Aldakheel ; Barbara S. Connolly ; Carmen Gasca-Salas ; Drew S. Kern ; Jennifer Jain ; Elizabeth J. Slow ; Achinoam Faust-Socher ; Sam Kim ; Ruksana Azhu Valappil ; Farah Kausar ; Ekaterina Rogaeva ; J. William Langston ; Caroline M. Tanner ; Birgitt Schüle ; Anthony E. Lang ; Samuel M. Goldman ; Connie MarrasSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2017.
Abstract
Heart rate variability is reduced in idiopathic PD, indicating cardiac autonomic dysfunction likely resulting from peripheral autonomic synucleinopathy. Little is known about heart rate variability in leucine-rich repeat kinase 2-associated PD.
DOI: 10.1002/mds.26896
PubMed: 28071824
Links to Exploration step
pubmed:28071824Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.</title><author><name sortKey="Visanji, Naomi P" sort="Visanji, Naomi P" uniqKey="Visanji N" first="Naomi P" last="Visanji">Naomi P. Visanji</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Bhudhikanok, Grace S" sort="Bhudhikanok, Grace S" uniqKey="Bhudhikanok G" first="Grace S" last="Bhudhikanok">Grace S. Bhudhikanok</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mestre, Tiago A" sort="Mestre, Tiago A" uniqKey="Mestre T" first="Tiago A" last="Mestre">Tiago A. Mestre</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Ghate, Taneera" sort="Ghate, Taneera" uniqKey="Ghate T" first="Taneera" last="Ghate">Taneera Ghate</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Udupa, Kaviraj" sort="Udupa, Kaviraj" uniqKey="Udupa K" first="Kaviraj" last="Udupa">Kaviraj Udupa</name><affiliation><nlm:affiliation>Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Aldakheel, Amaal" sort="Aldakheel, Amaal" uniqKey="Aldakheel A" first="Amaal" last="Aldakheel">Amaal Aldakheel</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Connolly, Barbara S" sort="Connolly, Barbara S" uniqKey="Connolly B" first="Barbara S" last="Connolly">Barbara S. Connolly</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Gasca Salas, Carmen" sort="Gasca Salas, Carmen" uniqKey="Gasca Salas C" first="Carmen" last="Gasca-Salas">Carmen Gasca-Salas</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Kern, Drew S" sort="Kern, Drew S" uniqKey="Kern D" first="Drew S" last="Kern">Drew S. Kern</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Jain, Jennifer" sort="Jain, Jennifer" uniqKey="Jain J" first="Jennifer" last="Jain">Jennifer Jain</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Slow, Elizabeth J" sort="Slow, Elizabeth J" uniqKey="Slow E" first="Elizabeth J" last="Slow">Elizabeth J. Slow</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Faust Socher, Achinoam" sort="Faust Socher, Achinoam" uniqKey="Faust Socher A" first="Achinoam" last="Faust-Socher">Achinoam Faust-Socher</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sam" sort="Kim, Sam" uniqKey="Kim S" first="Sam" last="Kim">Sam Kim</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Azhu Valappil, Ruksana" sort="Azhu Valappil, Ruksana" uniqKey="Azhu Valappil R" first="Ruksana" last="Azhu Valappil">Ruksana Azhu Valappil</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kausar, Farah" sort="Kausar, Farah" uniqKey="Kausar F" first="Farah" last="Kausar">Farah Kausar</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Rogaeva, Ekaterina" sort="Rogaeva, Ekaterina" uniqKey="Rogaeva E" first="Ekaterina" last="Rogaeva">Ekaterina Rogaeva</name><affiliation><nlm:affiliation>Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="William Langston, J" sort="William Langston, J" uniqKey="William Langston J" first="J" last="William Langston">J. William Langston</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M" last="Tanner">Caroline M. Tanner</name><affiliation><nlm:affiliation>University of California, San Francisco, San Francisco, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Schule, Birgitt" sort="Schule, Birgitt" uniqKey="Schule B" first="Birgitt" last="Schüle">Birgitt Schüle</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Goldman, Samuel M" sort="Goldman, Samuel M" uniqKey="Goldman S" first="Samuel M" last="Goldman">Samuel M. Goldman</name><affiliation><nlm:affiliation>University of California, San Francisco, San Francisco, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Marras, Connie" sort="Marras, Connie" uniqKey="Marras C" first="Connie" last="Marras">Connie Marras</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28071824</idno><idno type="pmid">28071824</idno><idno type="doi">10.1002/mds.26896</idno><idno type="wicri:Area/PubMed/Corpus">000026</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000026</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.</title><author><name sortKey="Visanji, Naomi P" sort="Visanji, Naomi P" uniqKey="Visanji N" first="Naomi P" last="Visanji">Naomi P. Visanji</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Bhudhikanok, Grace S" sort="Bhudhikanok, Grace S" uniqKey="Bhudhikanok G" first="Grace S" last="Bhudhikanok">Grace S. Bhudhikanok</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mestre, Tiago A" sort="Mestre, Tiago A" uniqKey="Mestre T" first="Tiago A" last="Mestre">Tiago A. Mestre</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Ghate, Taneera" sort="Ghate, Taneera" uniqKey="Ghate T" first="Taneera" last="Ghate">Taneera Ghate</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Udupa, Kaviraj" sort="Udupa, Kaviraj" uniqKey="Udupa K" first="Kaviraj" last="Udupa">Kaviraj Udupa</name><affiliation><nlm:affiliation>Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Aldakheel, Amaal" sort="Aldakheel, Amaal" uniqKey="Aldakheel A" first="Amaal" last="Aldakheel">Amaal Aldakheel</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Connolly, Barbara S" sort="Connolly, Barbara S" uniqKey="Connolly B" first="Barbara S" last="Connolly">Barbara S. Connolly</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Gasca Salas, Carmen" sort="Gasca Salas, Carmen" uniqKey="Gasca Salas C" first="Carmen" last="Gasca-Salas">Carmen Gasca-Salas</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Kern, Drew S" sort="Kern, Drew S" uniqKey="Kern D" first="Drew S" last="Kern">Drew S. Kern</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Jain, Jennifer" sort="Jain, Jennifer" uniqKey="Jain J" first="Jennifer" last="Jain">Jennifer Jain</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Slow, Elizabeth J" sort="Slow, Elizabeth J" uniqKey="Slow E" first="Elizabeth J" last="Slow">Elizabeth J. Slow</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Faust Socher, Achinoam" sort="Faust Socher, Achinoam" uniqKey="Faust Socher A" first="Achinoam" last="Faust-Socher">Achinoam Faust-Socher</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sam" sort="Kim, Sam" uniqKey="Kim S" first="Sam" last="Kim">Sam Kim</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Azhu Valappil, Ruksana" sort="Azhu Valappil, Ruksana" uniqKey="Azhu Valappil R" first="Ruksana" last="Azhu Valappil">Ruksana Azhu Valappil</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kausar, Farah" sort="Kausar, Farah" uniqKey="Kausar F" first="Farah" last="Kausar">Farah Kausar</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Rogaeva, Ekaterina" sort="Rogaeva, Ekaterina" uniqKey="Rogaeva E" first="Ekaterina" last="Rogaeva">Ekaterina Rogaeva</name><affiliation><nlm:affiliation>Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="William Langston, J" sort="William Langston, J" uniqKey="William Langston J" first="J" last="William Langston">J. William Langston</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M" last="Tanner">Caroline M. Tanner</name><affiliation><nlm:affiliation>University of California, San Francisco, San Francisco, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Schule, Birgitt" sort="Schule, Birgitt" uniqKey="Schule B" first="Birgitt" last="Schüle">Birgitt Schüle</name><affiliation><nlm:affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Goldman, Samuel M" sort="Goldman, Samuel M" uniqKey="Goldman S" first="Samuel M" last="Goldman">Samuel M. Goldman</name><affiliation><nlm:affiliation>University of California, San Francisco, San Francisco, California, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Marras, Connie" sort="Marras, Connie" uniqKey="Marras C" first="Connie" last="Marras">Connie Marras</name><affiliation><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Heart rate variability is reduced in idiopathic PD, indicating cardiac autonomic dysfunction likely resulting from peripheral autonomic synucleinopathy. Little is known about heart rate variability in leucine-rich repeat kinase 2-associated PD.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28071824</PMID><DateCreated><Year>2017</Year><Month>01</Month><Day>10</Day></DateCreated><DateRevised><Year>2017</Year><Month>04</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>32</Volume><Issue>4</Issue><PubDate><Year>2017</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.</ArticleTitle><Pagination><MedlinePgn>610-614</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.26896</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Heart rate variability is reduced in idiopathic PD, indicating cardiac autonomic dysfunction likely resulting from peripheral autonomic synucleinopathy. Little is known about heart rate variability in leucine-rich repeat kinase 2-associated PD.</AbstractText><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">This study investigated heart rate variability in LRRK2-associated PD.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Resting electrocardiograms were obtained from 20 individuals with LRRK2-associated PD, 37 nonmanifesting carriers, 48 related noncarriers, 26 idiopathic PD patients, and 32 controls. Linear regression modelling compared time and frequency domain values, adjusting for age, sex, heart rate, and disease duration.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Low-frequency power and the ratio of low-high frequency power were reduced in idiopathic PD versus controls (P < .008, P < .029 respectively). In contrast, individuals with LRRK2-associated PD were not statistically different from controls in any parameter measured. Furthermore, all parameters trended toward being higher in LRRK2-associated PD when compared with idiopathic PD.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Heart rate variability may remain intact in LRRK2-associated PD, adding to a growing literature supporting clinical-pathologic differences between LRRK2-associated and idiopathic PD. © 2017 International Parkinson and Movement Disorder Society.</AbstractText><CopyrightInformation>© 2017 International Parkinson and Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Visanji</LastName><ForeName>Naomi P</ForeName><Initials>NP</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhudhikanok</LastName><ForeName>Grace S</ForeName><Initials>GS</Initials><AffiliationInfo><Affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mestre</LastName><ForeName>Tiago A</ForeName><Initials>TA</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ghate</LastName><ForeName>Taneera</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Udupa</LastName><ForeName>Kaviraj</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>AlDakheel</LastName><ForeName>Amaal</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Connolly</LastName><ForeName>Barbara S</ForeName><Initials>BS</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gasca-Salas</LastName><ForeName>Carmen</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kern</LastName><ForeName>Drew S</ForeName><Initials>DS</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jain</LastName><ForeName>Jennifer</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Slow</LastName><ForeName>Elizabeth J</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Faust-Socher</LastName><ForeName>Achinoam</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Sam</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Azhu Valappil</LastName><ForeName>Ruksana</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kausar</LastName><ForeName>Farah</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rogaeva</LastName><ForeName>Ekaterina</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>William Langston</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tanner</LastName><ForeName>Caroline M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>University of California, San Francisco, San Francisco, California, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>San Francisco Veterans Affairs Health Care System, San Francisco, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schüle</LastName><ForeName>Birgitt</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>The Parkinson's Institute and Clinical Center, Sunnyvale, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lang</LastName><ForeName>Anthony E</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goldman</LastName><ForeName>Samuel M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>University of California, San Francisco, San Francisco, California, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>San Francisco Veterans Affairs Health Care System, San Francisco, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marras</LastName><ForeName>Connie</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Morton and Gloria Shulman Movement Disorders Centre and Edmund J Saffra Program in Parkinson's Disease, Tornto Western Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>01</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">LRRK2</Keyword><Keyword MajorTopicYN="N">Parkinson's disease</Keyword><Keyword MajorTopicYN="N">autonomic dysfunction</Keyword><Keyword MajorTopicYN="N">heart rate variability</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>07</Month><Day>05</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>11</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>11</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>1</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>1</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>1</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28071824</ArticleId><ArticleId IdType="doi">10.1002/mds.26896</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000026 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000026 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:28071824
|texte= Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:28071824" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |