Memory and learning in early Parkinson's disease: evidence for a "frontal lobe syndrome".
Identifieur interne : 001A84 ( PubMed/Checkpoint ); précédent : 001A83; suivant : 001A85Memory and learning in early Parkinson's disease: evidence for a "frontal lobe syndrome".
Auteurs : A E Taylor [Canada] ; J A Saint-Cyr ; A E LangSource :
- Brain and cognition [ 0278-2626 ] ; 1990.
English descriptors
- KwdEn :
- Corpus Striatum (physiology), Female, Frontal Lobe (physiopathology), Humans, Male, Memory (physiology), Memory, Short-Term (physiology), Mental Recall (physiology), Middle Aged, Neural Pathways (physiopathology), Paired-Associate Learning (physiology), Parkinson Disease (physiopathology), Psychomotor Performance (physiology), Reaction Time (physiology), Retention (Psychology) (physiology), Verbal Learning (physiology), Wechsler Scales.
- MESH :
- physiology : Corpus Striatum, Memory, Memory, Short-Term, Mental Recall, Paired-Associate Learning, Psychomotor Performance, Reaction Time, Retention (Psychology), Verbal Learning.
- physiopathology : Frontal Lobe, Neural Pathways, Parkinson Disease.
- Female, Humans, Male, Middle Aged, Wechsler Scales.
Abstract
Fifteen untreated patients in the earliest stages of Parkinson's disease were compared to fifteen age- and intellectually matched control subjects on a number of memory tasks assessing short- and long-term recall of both meaningful and unrelated material, semantic relations in the organization of memory, priming, and source forgetting, and the ability to form new stimulus-response associations under conditions of maximal task interference. While patients demonstrated considerable evidence of preserved function, impaired performance on a subgroup of tasks was consistent with selective frontostriatal system involvement. These findings are discussed with reference to the underlying pathological processes in Parkinson's disease.
PubMed: 2390235
Affiliations:
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pubmed:2390235Le document en format XML
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While patients demonstrated considerable evidence of preserved function, impaired performance on a subgroup of tasks was consistent with selective frontostriatal system involvement. These findings are discussed with reference to the underlying pathological processes in Parkinson's disease.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2390235</PMID><DateCreated><Year>1990</Year><Month>10</Month><Day>02</Day></DateCreated><DateCompleted><Year>1990</Year><Month>10</Month><Day>02</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0278-2626</ISSN><JournalIssue CitedMedium="Print"><Volume>13</Volume><Issue>2</Issue><PubDate><Year>1990</Year><Month>Jul</Month></PubDate></JournalIssue><Title>Brain and cognition</Title><ISOAbbreviation>Brain Cogn</ISOAbbreviation></Journal><ArticleTitle>Memory and learning in early Parkinson's disease: evidence for a "frontal lobe syndrome".</ArticleTitle><Pagination><MedlinePgn>211-32</MedlinePgn></Pagination><Abstract><AbstractText>Fifteen untreated patients in the earliest stages of Parkinson's disease were compared to fifteen age- and intellectually matched control subjects on a number of memory tasks assessing short- and long-term recall of both meaningful and unrelated material, semantic relations in the organization of memory, priming, and source forgetting, and the ability to form new stimulus-response associations under conditions of maximal task interference. While patients demonstrated considerable evidence of preserved function, impaired performance on a subgroup of tasks was consistent with selective frontostriatal system involvement. 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