Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Identifieur interne : 001A51 ( PubMed/Checkpoint ); précédent : 001A50; suivant : 001A52Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Auteurs : B M Clarke [Canada] ; A. Upton ; H. Griffin ; P. HudobaSource :
- Pacing and clinical electrophysiology : PACE [ 0147-8389 ] ; 1991.
English descriptors
- KwdEn :
- Adult, Carbamazepine (blood), Carbamazepine (therapeutic use), Cognition (drug effects), Cognition (physiology), Electric Stimulation Therapy, Epilepsy, Temporal Lobe (drug therapy), Epilepsy, Temporal Lobe (physiopathology), Epilepsy, Temporal Lobe (therapy), Humans, Male, Parkinson Disease (physiopathology), Phenobarbital (blood), Phenobarbital (therapeutic use), Phenytoin (blood), Phenytoin (therapeutic use), Postural Balance (drug effects), Postural Balance (physiology), Reaction Time, Time Factors, Vagus Nerve (physiology), Valproic Acid (blood), Valproic Acid (therapeutic use).
- MESH :
- chemical , blood : Carbamazepine, Phenobarbital, Phenytoin, Valproic Acid.
- chemical , therapeutic use : Carbamazepine, Phenobarbital, Phenytoin, Valproic Acid.
- drug effects : Cognition, Postural Balance.
- drug therapy : Epilepsy, Temporal Lobe.
- physiology : Cognition, Postural Balance, Vagus Nerve.
- physiopathology : Epilepsy, Temporal Lobe, Parkinson Disease.
- therapy : Epilepsy, Temporal Lobe.
- Adult, Electric Stimulation Therapy, Humans, Male, Reaction Time, Time Factors.
Abstract
Balance and cognition were assessed in two patients with uncontrolled complex partial seizures. The patients were on anticonvulsant medications and were treated with left vagal stimulation. Balance and cognition were assessed before and after vagal stimulation, and the results were compared with age matched controls and older patients with Parkinson's disease. Severe impairments of function were found in the epileptic patients, and such negative effects of medication make vagal stimulation a potentially practical alternative treatment for uncontrolled epilepsy.
PubMed: 1705340
Affiliations:
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Hudoba</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1991">1991</date><idno type="RBID">pubmed:1705340</idno><idno type="pmid">1705340</idno><idno type="wicri:Area/PubMed/Corpus">001B43</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001B43</idno><idno type="wicri:Area/PubMed/Curation">001B43</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001B43</idno><idno type="wicri:Area/PubMed/Checkpoint">001B43</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001B43</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.</title><author><name sortKey="Clarke, B M" sort="Clarke, B M" uniqKey="Clarke B" first="B M" last="Clarke">B M Clarke</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University Medical Centre, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University Medical Centre, Hamilton, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Upton, A" sort="Upton, A" uniqKey="Upton A" first="A" last="Upton">A. Upton</name></author><author><name sortKey="Griffin, H" sort="Griffin, H" uniqKey="Griffin H" first="H" last="Griffin">H. Griffin</name></author><author><name sortKey="Hudoba, P" sort="Hudoba, P" uniqKey="Hudoba P" first="P" last="Hudoba">P. Hudoba</name></author></analytic><series><title level="j">Pacing and clinical electrophysiology : PACE</title><idno type="ISSN">0147-8389</idno><imprint><date when="1991" type="published">1991</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Carbamazepine (blood)</term><term>Carbamazepine (therapeutic use)</term><term>Cognition (drug effects)</term><term>Cognition (physiology)</term><term>Electric Stimulation Therapy</term><term>Epilepsy, Temporal Lobe (drug therapy)</term><term>Epilepsy, Temporal Lobe (physiopathology)</term><term>Epilepsy, Temporal Lobe (therapy)</term><term>Humans</term><term>Male</term><term>Parkinson Disease (physiopathology)</term><term>Phenobarbital (blood)</term><term>Phenobarbital (therapeutic use)</term><term>Phenytoin (blood)</term><term>Phenytoin (therapeutic use)</term><term>Postural Balance (drug effects)</term><term>Postural Balance (physiology)</term><term>Reaction Time</term><term>Time Factors</term><term>Vagus Nerve (physiology)</term><term>Valproic Acid (blood)</term><term>Valproic Acid (therapeutic use)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Carbamazepine</term><term>Phenobarbital</term><term>Phenytoin</term><term>Valproic Acid</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Carbamazepine</term><term>Phenobarbital</term><term>Phenytoin</term><term>Valproic Acid</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Cognition</term><term>Postural Balance</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Epilepsy, Temporal Lobe</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Cognition</term><term>Postural Balance</term><term>Vagus Nerve</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Epilepsy, Temporal Lobe</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Epilepsy, Temporal Lobe</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Electric Stimulation Therapy</term><term>Humans</term><term>Male</term><term>Reaction Time</term><term>Time Factors</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Balance and cognition were assessed in two patients with uncontrolled complex partial seizures. The patients were on anticonvulsant medications and were treated with left vagal stimulation. Balance and cognition were assessed before and after vagal stimulation, and the results were compared with age matched controls and older patients with Parkinson's disease. Severe impairments of function were found in the epileptic patients, and such negative effects of medication make vagal stimulation a potentially practical alternative treatment for uncontrolled epilepsy.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">1705340</PMID><DateCreated><Year>1991</Year><Month>04</Month><Day>01</Day></DateCreated><DateCompleted><Year>1991</Year><Month>04</Month><Day>01</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0147-8389</ISSN><JournalIssue CitedMedium="Print"><Volume>14</Volume><Issue>1</Issue><PubDate><Year>1991</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Pacing and clinical electrophysiology : PACE</Title><ISOAbbreviation>Pacing Clin Electrophysiol</ISOAbbreviation></Journal><ArticleTitle>Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.</ArticleTitle><Pagination><MedlinePgn>77-85</MedlinePgn></Pagination><Abstract><AbstractText>Balance and cognition were assessed in two patients with uncontrolled complex partial seizures. The patients were on anticonvulsant medications and were treated with left vagal stimulation. Balance and cognition were assessed before and after vagal stimulation, and the results were compared with age matched controls and older patients with Parkinson's disease. Severe impairments of function were found in the epileptic patients, and such negative effects of medication make vagal stimulation a potentially practical alternative treatment for uncontrolled epilepsy.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Clarke</LastName><ForeName>B M</ForeName><Initials>BM</Initials><AffiliationInfo><Affiliation>McMaster University Medical Centre, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Upton</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Griffin</LastName><ForeName>H</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Hudoba</LastName><ForeName>P</ForeName><Initials>P</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. 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MajorTopicYN="N">Carbamazepine</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003071" MajorTopicYN="N">Cognition</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004599" MajorTopicYN="Y">Electric Stimulation Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004833" MajorTopicYN="N">Epilepsy, Temporal Lobe</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010634" MajorTopicYN="N">Phenobarbital</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010672" MajorTopicYN="N">Phenytoin</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004856" MajorTopicYN="N">Postural Balance</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011930" MajorTopicYN="N">Reaction Time</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014630" MajorTopicYN="N">Vagus Nerve</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014635" MajorTopicYN="N">Valproic Acid</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1991</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1991</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1991</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">1705340</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Griffin, H" sort="Griffin, H" uniqKey="Griffin H" first="H" last="Griffin">H. Griffin</name><name sortKey="Hudoba, P" sort="Hudoba, P" uniqKey="Hudoba P" first="P" last="Hudoba">P. Hudoba</name><name sortKey="Upton, A" sort="Upton, A" uniqKey="Upton A" first="A" last="Upton">A. Upton</name></noCountry><country name="Canada"><noRegion><name sortKey="Clarke, B M" sort="Clarke, B M" uniqKey="Clarke B" first="B M" last="Clarke">B M Clarke</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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