ParkinsonCanadaV1, PubMed, Checkpoint, bibRecord, 001911

A case-control study of Parkinson's disease in a horticultural region of British Columbia.

Identifieur interne : 001911 ( PubMed/Checkpoint ); précédent : 001910; suivant : 001912

A case-control study of Parkinson's disease in a horticultural region of British Columbia.

Auteurs : C. Hertzman [Canada] ; M. Wiens ; B. Snow ; S. Kelly ; D. Calne

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1994.

RBID : pubmed:8139607

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Agricultural Workers' Diseases (chemically induced), Agricultural Workers' Diseases (diagnosis), British Columbia, Case-Control Studies, Female, Humans, Male, Middle Aged, Occupational Exposure (adverse effects), Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (diagnosis), Pesticides (adverse effects), Risk Factors.
MESH :
- chemical , adverse effects : Pesticides.
- geographic : British Columbia.
- adverse effects : Occupational Exposure.
- chemically induced : Agricultural Workers' Diseases, Parkinson Disease, Secondary.
- diagnosis : Agricultural Workers' Diseases, Parkinson Disease, Secondary.
- Aged, Aged, 80 and over, Case-Control Studies, Female, Humans, Male, Middle Aged, Risk Factors.

Abstract

We compared personal histories of 127 cases and 245 controls to identify possible environmental risk factors for idiopathic parkinsonism (IP). Of our controls, 121 had cardiac disease (CD) and 124 were randomly selected from electoral lists (voters). Using logistic regression and adjusting for sex and age, we ran separate analyses: IP versus CD and IP versus voters. A full occupational history was collected, as was known contact with all pesticides associated with the tree fruit sector of the agricultural industry. We found a significant association between IP and having had an occupation in which exposure through handling or directly contacting pesticides was probable, but no specific chemicals were associated with IP. We conclude that although occupations involving the use of agricultural chemicals may predispose to the development of IP, it seems likely that the pathogenesis is multifactorial rather than related to a specific agent.

DOI: 10.1002/mds.870090111
PubMed: 8139607

Affiliations:

Canada

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pubmed:8139607

Le document en format XML

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<author><name sortKey="Hertzman, C" sort="Hertzman, C" uniqKey="Hertzman C" first="C" last="Hertzman">C. Hertzman</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Health Care and Epidemiology, University of British Columbia, Vancouver</wicri:regionArea>
<wicri:noRegion>Vancouver</wicri:noRegion>
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<author><name sortKey="Wiens, M" sort="Wiens, M" uniqKey="Wiens M" first="M" last="Wiens">M. Wiens</name>
</author>
<author><name sortKey="Snow, B" sort="Snow, B" uniqKey="Snow B" first="B" last="Snow">B. Snow</name>
</author>
<author><name sortKey="Kelly, S" sort="Kelly, S" uniqKey="Kelly S" first="S" last="Kelly">S. Kelly</name>
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<author><name sortKey="Calne, D" sort="Calne, D" uniqKey="Calne D" first="D" last="Calne">D. Calne</name>
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<term>British Columbia</term>
<term>Case-Control Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Occupational Exposure (adverse effects)</term>
<term>Parkinson Disease, Secondary (chemically induced)</term>
<term>Parkinson Disease, Secondary (diagnosis)</term>
<term>Pesticides (adverse effects)</term>
<term>Risk Factors</term>
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<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Pesticides</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Occupational Exposure</term>
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<term>Parkinson Disease, Secondary</term>
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<front><div type="abstract" xml:lang="en">We compared personal histories of 127 cases and 245 controls to identify possible environmental risk factors for idiopathic parkinsonism (IP). Of our controls, 121 had cardiac disease (CD) and 124 were randomly selected from electoral lists (voters). Using logistic regression and adjusting for sex and age, we ran separate analyses: IP versus CD and IP versus voters. A full occupational history was collected, as was known contact with all pesticides associated with the tree fruit sector of the agricultural industry. We found a significant association between IP and having had an occupation in which exposure through handling or directly contacting pesticides was probable, but no specific chemicals were associated with IP. We conclude that although occupations involving the use of agricultural chemicals may predispose to the development of IP, it seems likely that the pathogenesis is multifactorial rather than related to a specific agent.</div>
</front>
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<Issue>1</Issue>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>A case-control study of Parkinson's disease in a horticultural region of British Columbia.</ArticleTitle>
<Pagination><MedlinePgn>69-75</MedlinePgn>
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<Abstract><AbstractText>We compared personal histories of 127 cases and 245 controls to identify possible environmental risk factors for idiopathic parkinsonism (IP). Of our controls, 121 had cardiac disease (CD) and 124 were randomly selected from electoral lists (voters). Using logistic regression and adjusting for sex and age, we ran separate analyses: IP versus CD and IP versus voters. A full occupational history was collected, as was known contact with all pesticides associated with the tree fruit sector of the agricultural industry. We found a significant association between IP and having had an occupation in which exposure through handling or directly contacting pesticides was probable, but no specific chemicals were associated with IP. We conclude that although occupations involving the use of agricultural chemicals may predispose to the development of IP, it seems likely that the pathogenesis is multifactorial rather than related to a specific agent.</AbstractText>
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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

A case-control study of Parkinson's disease in a horticultural region of British Columbia.

A case-control study of Parkinson's disease in a horticultural region of British Columbia.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki