La maladie de Parkinson au Canada (serveur d'exploration)

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Hemiparkinsonism-somatic hemiatrophy syndrome.

Identifieur interne : 001461 ( PubMed/Checkpoint ); précédent : 001460; suivant : 001462

Hemiparkinsonism-somatic hemiatrophy syndrome.

Auteurs : Mary Jenkins [Canada] ; Dan Mendonca ; Andrew Parrent ; Mandar S. Jog

Source :

RBID : pubmed:12035843

English descriptors

Abstract

This paper highlights the hemiparkinsonism-hemiatrophy (HPHA) syndrome as a unique presentation of the parkinsonian state. Clinically relevant diagnostic and treatment aspects are reviewed.

PubMed: 12035843


Affiliations:


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pubmed:12035843

Le document en format XML

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<nlm:affiliation>Department of Clinical Neurological Sciences, London Health Sciences Centre, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
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<wicri:noRegion>ON</wicri:noRegion>
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<name sortKey="Mendonca, Dan" sort="Mendonca, Dan" uniqKey="Mendonca D" first="Dan" last="Mendonca">Dan Mendonca</name>
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<name sortKey="Parrent, Andrew" sort="Parrent, Andrew" uniqKey="Parrent A" first="Andrew" last="Parrent">Andrew Parrent</name>
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<name sortKey="Jog, Mandar S" sort="Jog, Mandar S" uniqKey="Jog M" first="Mandar S" last="Jog">Mandar S. Jog</name>
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<title level="j">The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques</title>
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<term>Growth Disorders</term>
<term>Humans</term>
<term>Musculoskeletal Abnormalities (pathology)</term>
<term>Musculoskeletal Abnormalities (physiopathology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (therapy)</term>
<term>Subthalamic Nucleus (pathology)</term>
<term>Subthalamic Nucleus (physiopathology)</term>
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<div type="abstract" xml:lang="en">This paper highlights the hemiparkinsonism-hemiatrophy (HPHA) syndrome as a unique presentation of the parkinsonian state. Clinically relevant diagnostic and treatment aspects are reviewed.</div>
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<Title>The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques</Title>
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<ArticleTitle>Hemiparkinsonism-somatic hemiatrophy syndrome.</ArticleTitle>
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<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">This paper highlights the hemiparkinsonism-hemiatrophy (HPHA) syndrome as a unique presentation of the parkinsonian state. Clinically relevant diagnostic and treatment aspects are reviewed.</AbstractText>
<AbstractText Label="METHOD" NlmCategory="METHODS">We report a case of HPHA, in a 21-year-old, otherwise healthy, woman. Clinical and radiographic features of our case are presented. We also review the current literature on the clinical, radiological and pathophysiological mechanisms of HPHA.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In our case, despite the lack of benefit from anticholinergics and dopamine agonists (the patient declined treatment with levodopa), the patient showed a dramatic improvement with subthalamic nucleus stimulator (STN) implantation. There are no reported cases of use of STN stimulator in HPHA.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Hemiparkinsonism-hemiatrophy is a distinct entity that may be clinically and pathogenetically different from idiopathic Parkinson's disease; hence, HPHA needs to be considered as a possible syndrome in patients that have persistent unilateral parkinsonism. As medications are reported to be unhelpful in HPHA cases, early surgical intervention may be an option, such as in our case.</AbstractText>
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