Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes.
Identifieur interne : 000164 ( PubMed/Checkpoint ); précédent : 000163; suivant : 000165Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes.
Auteurs : Sadhna Phanse [Canada] ; Cuihong Wan [États-Unis] ; Blake Borgeson [Canada] ; Fan Tu [États-Unis] ; Kevin Drew [États-Unis] ; Greg Clark [Canada] ; Xuejian Xiong [Canada] ; Olga Kagan [Canada] ; Julian Kwan [Canada] ; Alexandr Bezginov [Canada] ; Kyle Chessman [Canada] ; Swati Pal [Canada] ; Graham Cromar [Canada] ; Ophelia Papoulas [États-Unis] ; Zuyao Ni [Canada] ; Daniel R. Boutz [États-Unis] ; Snejana Stoilova [Canada] ; Pierre C. Havugimana [Canada] ; Xinghua Guo [Canada] ; Ramy H. Malty [Canada] ; Mihail Sarov [Allemagne] ; Jack Greenblatt [Canada] ; Mohan Babu [Canada] ; W Brent Derry [Canada] ; Elisabeth R. Tillier [Canada] ; John B. Wallingford [États-Unis] ; John Parkinson [Canada] ; Edward M. Marcotte [États-Unis] ; Andrew Emili [Canada]Source :
- Data in brief ; 2016.
Abstract
Our analysis examines the conservation of multiprotein complexes among metazoa through use of high resolution biochemical fractionation and precision mass spectrometry applied to soluble cell extracts from 5 representative model organisms Caenorhabditis elegans, Drosophila melanogaster, Mus musculus, Strongylocentrotus purpuratus, and Homo sapiens. The interaction network obtained from the data was validated globally in 4 distant species (Xenopus laevis, Nematostella vectensis, Dictyostelium discoideum, Saccharomyces cerevisiae) and locally by targeted affinity-purification experiments. Here we provide details of our massive set of supporting biochemical fractionation data available via ProteomeXchange (PXD002319-PXD002328), PPIs via BioGRID (185267); and interaction network projections via (http://metazoa.med.utoronto.ca) made fully accessible to allow further exploration. The datasets here are related to the research article on metazoan macromolecular complexes in Nature [1].
DOI: 10.1016/j.dib.2015.11.062
PubMed: 26870755
Affiliations:
- Allemagne, Canada, États-Unis
- District de Dresde, Manitoba, Ontario, Saxe (Land), Texas
- Austin (Texas), Dresde, Saskatchewan, Toronto
- Université de Regina, Université de Toronto, Université du Texas à Austin
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Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kagan, Olga" sort="Kagan, Olga" uniqKey="Kagan O" first="Olga" last="Kagan">Olga Kagan</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kwan, Julian" sort="Kwan, Julian" uniqKey="Kwan J" first="Julian" last="Kwan">Julian Kwan</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bezginov, Alexandr" sort="Bezginov, Alexandr" uniqKey="Bezginov A" first="Alexandr" last="Bezginov">Alexandr Bezginov</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medical Biophysics, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Chessman, Kyle" sort="Chessman, Kyle" uniqKey="Chessman K" first="Kyle" last="Chessman">Kyle Chessman</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Pal, Swati" sort="Pal, Swati" uniqKey="Pal S" first="Swati" last="Pal">Swati Pal</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Cromar, Graham" sort="Cromar, Graham" uniqKey="Cromar G" first="Graham" last="Cromar">Graham Cromar</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Papoulas, Ophelia" sort="Papoulas, Ophelia" uniqKey="Papoulas O" first="Ophelia" last="Papoulas">Ophelia Papoulas</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Ni, Zuyao" sort="Ni, Zuyao" uniqKey="Ni Z" first="Zuyao" last="Ni">Zuyao Ni</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Boutz, Daniel R" sort="Boutz, Daniel R" uniqKey="Boutz D" first="Daniel R" last="Boutz">Daniel R. Boutz</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Stoilova, Snejana" sort="Stoilova, Snejana" uniqKey="Stoilova S" first="Snejana" last="Stoilova">Snejana Stoilova</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Havugimana, Pierre C" sort="Havugimana, Pierre C" uniqKey="Havugimana P" first="Pierre C" last="Havugimana">Pierre C. Havugimana</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Guo, Xinghua" sort="Guo, Xinghua" uniqKey="Guo X" first="Xinghua" last="Guo">Xinghua Guo</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Malty, Ramy H" sort="Malty, Ramy H" uniqKey="Malty R" first="Ramy H" last="Malty">Ramy H. Malty</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Regina, Regina, Saskatchewan, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry, University of Regina, Regina, Saskatchewan</wicri:regionArea><orgName type="university">Université de Regina</orgName><placeName><settlement type="city">Saskatchewan</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Sarov, Mihail" sort="Sarov, Mihail" uniqKey="Sarov M" first="Mihail" last="Sarov">Mihail Sarov</name><affiliation wicri:level="3"><nlm:affiliation>Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute of Molecular Cell Biology and Genetics, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Greenblatt, Jack" sort="Greenblatt, Jack" uniqKey="Greenblatt J" first="Jack" last="Greenblatt">Jack Greenblatt</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Babu, Mohan" sort="Babu, Mohan" uniqKey="Babu M" first="Mohan" last="Babu">Mohan Babu</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Regina, Regina, Saskatchewan, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry, University of Regina, Regina, Saskatchewan</wicri:regionArea><orgName type="university">Université de Regina</orgName><placeName><settlement type="city">Saskatchewan</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Derry, W Brent" sort="Derry, W Brent" uniqKey="Derry W" first="W Brent" last="Derry">W Brent Derry</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Tillier, Elisabeth R" sort="Tillier, Elisabeth R" uniqKey="Tillier E" first="Elisabeth R" last="Tillier">Elisabeth R. Tillier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medical Biophysics, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Wallingford, John B" sort="Wallingford, John B" uniqKey="Wallingford J" first="John B" last="Wallingford">John B. Wallingford</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Marcotte, Edward M" sort="Marcotte, Edward M" uniqKey="Marcotte E" first="Edward M" last="Marcotte">Edward M. Marcotte</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Emili, Andrew" sort="Emili, Andrew" uniqKey="Emili A" first="Andrew" last="Emili">Andrew Emili</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26870755</idno><idno type="pmid">26870755</idno><idno type="doi">10.1016/j.dib.2015.11.062</idno><idno type="wicri:Area/PubMed/Corpus">000355</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000355</idno><idno type="wicri:Area/PubMed/Curation">000355</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000355</idno><idno type="wicri:Area/PubMed/Checkpoint">000355</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000355</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes.</title><author><name sortKey="Phanse, Sadhna" sort="Phanse, Sadhna" uniqKey="Phanse S" first="Sadhna" last="Phanse">Sadhna Phanse</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Wan, Cuihong" sort="Wan, Cuihong" uniqKey="Wan C" first="Cuihong" last="Wan">Cuihong Wan</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Toronto</settlement></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Borgeson, Blake" sort="Borgeson, Blake" uniqKey="Borgeson B" first="Blake" last="Borgeson">Blake Borgeson</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Tu, Fan" sort="Tu, Fan" uniqKey="Tu F" first="Fan" last="Tu">Fan Tu</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Drew, Kevin" sort="Drew, Kevin" uniqKey="Drew K" first="Kevin" last="Drew">Kevin Drew</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Clark, Greg" sort="Clark, Greg" uniqKey="Clark G" first="Greg" last="Clark">Greg Clark</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medical Biophysics, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Xiong, Xuejian" sort="Xiong, Xuejian" uniqKey="Xiong X" first="Xuejian" last="Xiong">Xuejian Xiong</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kagan, Olga" sort="Kagan, Olga" uniqKey="Kagan O" first="Olga" last="Kagan">Olga Kagan</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kwan, Julian" sort="Kwan, Julian" uniqKey="Kwan J" first="Julian" last="Kwan">Julian Kwan</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bezginov, Alexandr" sort="Bezginov, Alexandr" uniqKey="Bezginov A" first="Alexandr" last="Bezginov">Alexandr Bezginov</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medical Biophysics, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Chessman, Kyle" sort="Chessman, Kyle" uniqKey="Chessman K" first="Kyle" last="Chessman">Kyle Chessman</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Pal, Swati" sort="Pal, Swati" uniqKey="Pal S" first="Swati" last="Pal">Swati Pal</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Cromar, Graham" sort="Cromar, Graham" uniqKey="Cromar G" first="Graham" last="Cromar">Graham Cromar</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Papoulas, Ophelia" sort="Papoulas, Ophelia" uniqKey="Papoulas O" first="Ophelia" last="Papoulas">Ophelia Papoulas</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Ni, Zuyao" sort="Ni, Zuyao" uniqKey="Ni Z" first="Zuyao" last="Ni">Zuyao Ni</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Boutz, Daniel R" sort="Boutz, Daniel R" uniqKey="Boutz D" first="Daniel R" last="Boutz">Daniel R. Boutz</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Stoilova, Snejana" sort="Stoilova, Snejana" uniqKey="Stoilova S" first="Snejana" last="Stoilova">Snejana Stoilova</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Havugimana, Pierre C" sort="Havugimana, Pierre C" uniqKey="Havugimana P" first="Pierre C" last="Havugimana">Pierre C. Havugimana</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Guo, Xinghua" sort="Guo, Xinghua" uniqKey="Guo X" first="Xinghua" last="Guo">Xinghua Guo</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Malty, Ramy H" sort="Malty, Ramy H" uniqKey="Malty R" first="Ramy H" last="Malty">Ramy H. Malty</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Regina, Regina, Saskatchewan, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry, University of Regina, Regina, Saskatchewan</wicri:regionArea><orgName type="university">Université de Regina</orgName><placeName><settlement type="city">Saskatchewan</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Sarov, Mihail" sort="Sarov, Mihail" uniqKey="Sarov M" first="Mihail" last="Sarov">Mihail Sarov</name><affiliation wicri:level="3"><nlm:affiliation>Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute of Molecular Cell Biology and Genetics, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Greenblatt, Jack" sort="Greenblatt, Jack" uniqKey="Greenblatt J" first="Jack" last="Greenblatt">Jack Greenblatt</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Babu, Mohan" sort="Babu, Mohan" uniqKey="Babu M" first="Mohan" last="Babu">Mohan Babu</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Regina, Regina, Saskatchewan, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry, University of Regina, Regina, Saskatchewan</wicri:regionArea><orgName type="university">Université de Regina</orgName><placeName><settlement type="city">Saskatchewan</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Derry, W Brent" sort="Derry, W Brent" uniqKey="Derry W" first="W Brent" last="Derry">W Brent Derry</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Tillier, Elisabeth R" sort="Tillier, Elisabeth R" uniqKey="Tillier E" first="Elisabeth R" last="Tillier">Elisabeth R. Tillier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medical Biophysics, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Wallingford, John B" sort="Wallingford, John B" uniqKey="Wallingford J" first="John B" last="Wallingford">John B. Wallingford</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Marcotte, Edward M" sort="Marcotte, Edward M" uniqKey="Marcotte E" first="Edward M" last="Marcotte">Edward M. Marcotte</name><affiliation wicri:level="4"><nlm:affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region><settlement type="city">Austin (Texas)</settlement></placeName><orgName type="university">Université du Texas à Austin</orgName></affiliation></author><author><name sortKey="Emili, Andrew" sort="Emili, Andrew" uniqKey="Emili A" first="Andrew" last="Emili">Andrew Emili</name><affiliation wicri:level="4"><nlm:affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></analytic><series><title level="j">Data in brief</title><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Our analysis examines the conservation of multiprotein complexes among metazoa through use of high resolution biochemical fractionation and precision mass spectrometry applied to soluble cell extracts from 5 representative model organisms Caenorhabditis elegans, Drosophila melanogaster, Mus musculus, Strongylocentrotus purpuratus, and Homo sapiens. The interaction network obtained from the data was validated globally in 4 distant species (Xenopus laevis, Nematostella vectensis, Dictyostelium discoideum, Saccharomyces cerevisiae) and locally by targeted affinity-purification experiments. Here we provide details of our massive set of supporting biochemical fractionation data available via ProteomeXchange (PXD002319-PXD002328), PPIs via BioGRID (185267); and interaction network projections via (http://metazoa.med.utoronto.ca) made fully accessible to allow further exploration. The datasets here are related to the research article on metazoan macromolecular complexes in Nature [1].</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">26870755</PMID><DateCreated><Year>2016</Year><Month>02</Month><Day>12</Day></DateCreated><DateCompleted><Year>2016</Year><Month>02</Month><Day>12</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><JournalIssue CitedMedium="Print"><Volume>6</Volume><PubDate><Year>2016</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Data in brief</Title><ISOAbbreviation>Data Brief</ISOAbbreviation></Journal><ArticleTitle>Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes.</ArticleTitle><Pagination><MedlinePgn>715-21</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.dib.2015.11.062</ELocationID><Abstract><AbstractText>Our analysis examines the conservation of multiprotein complexes among metazoa through use of high resolution biochemical fractionation and precision mass spectrometry applied to soluble cell extracts from 5 representative model organisms Caenorhabditis elegans, Drosophila melanogaster, Mus musculus, Strongylocentrotus purpuratus, and Homo sapiens. The interaction network obtained from the data was validated globally in 4 distant species (Xenopus laevis, Nematostella vectensis, Dictyostelium discoideum, Saccharomyces cerevisiae) and locally by targeted affinity-purification experiments. Here we provide details of our massive set of supporting biochemical fractionation data available via ProteomeXchange (PXD002319-PXD002328), PPIs via BioGRID (185267); and interaction network projections via (http://metazoa.med.utoronto.ca) made fully accessible to allow further exploration. The datasets here are related to the research article on metazoan macromolecular complexes in Nature [1].</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Phanse</LastName><ForeName>Sadhna</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wan</LastName><ForeName>Cuihong</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borgeson</LastName><ForeName>Blake</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tu</LastName><ForeName>Fan</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Drew</LastName><ForeName>Kevin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Clark</LastName><ForeName>Greg</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xiong</LastName><ForeName>Xuejian</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kagan</LastName><ForeName>Olga</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kwan</LastName><ForeName>Julian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bezginov</LastName><ForeName>Alexandr</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chessman</LastName><ForeName>Kyle</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pal</LastName><ForeName>Swati</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cromar</LastName><ForeName>Graham</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papoulas</LastName><ForeName>Ophelia</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ni</LastName><ForeName>Zuyao</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boutz</LastName><ForeName>Daniel R</ForeName><Initials>DR</Initials><AffiliationInfo><Affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stoilova</LastName><ForeName>Snejana</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Havugimana</LastName><ForeName>Pierre C</ForeName><Initials>PC</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guo</LastName><ForeName>Xinghua</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Malty</LastName><ForeName>Ramy H</ForeName><Initials>RH</Initials><AffiliationInfo><Affiliation>Department of Biochemistry, University of Regina, Regina, Saskatchewan, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sarov</LastName><ForeName>Mihail</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Greenblatt</LastName><ForeName>Jack</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Babu</LastName><ForeName>Mohan</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Biochemistry, University of Regina, Regina, Saskatchewan, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Derry</LastName><ForeName>W Brent</ForeName><Initials>WB</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tillier</LastName><ForeName>Elisabeth R</ForeName><Initials>ER</Initials><AffiliationInfo><Affiliation>Department of Medical Biophysics, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wallingford</LastName><ForeName>John B</ForeName><Initials>JB</Initials><AffiliationInfo><Affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parkinson</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Hospital for Sick Children, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marcotte</LastName><ForeName>Edward M</ForeName><Initials>EM</Initials><AffiliationInfo><Affiliation>Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Emili</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>DP1 GM106408</GrantID><Acronym>GM</Acronym><Agency>NIGMS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>F32 GM112495</GrantID><Acronym>GM</Acronym><Agency>NIGMS NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>12</Month><Day>12</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Data Brief</MedlineTA><NlmUniqueID>101654995</NlmUniqueID><ISSNLinking>2352-3409</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Cell. 2011 Oct 28;147(3):690-703</RefSource><PMID Version="1">22036573</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Development. 2003 Sep;130(17):4217-27</RefSource><PMID Version="1">12874139</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2015 Sep 17;525(7569):339-44</RefSource><PMID Version="1">26344197</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Proteome Res. 2011 Jul 1;10(7):2949-58</RefSource><PMID Version="1">21488652</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Methods Mol Biol. 2008;420:359-71</RefSource><PMID Version="1">18641960</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2012 Aug 31;150(5):1068-81</RefSource><PMID Version="1">22939629</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Proteomics. 2013 Apr 9;81:102-11</RefSource><PMID Version="1">23063720</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nucleic Acids Res. 1991 May 11;19(9):2499</RefSource><PMID Version="1">2041787</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2011 May 27;145(5):787-99</RefSource><PMID Version="1">21620140</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genome Res. 2011 Jul;21(7):1109-21</RefSource><PMID Version="1">21536720</PMID></CommentsCorrections></CommentsCorrectionsList><OtherID Source="NLM">PMC4738005</OtherID><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Biochemical</Keyword><Keyword MajorTopicYN="N">Fractionation</Keyword><Keyword MajorTopicYN="N">Metazoa</Keyword><Keyword MajorTopicYN="N">Protein complexes</Keyword><Keyword MajorTopicYN="N">Proteomics</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>09</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2015</Year><Month>11</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>11</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26870755</ArticleId><ArticleId IdType="doi">10.1016/j.dib.2015.11.062</ArticleId><ArticleId IdType="pii">S2352-3409(15)00359-5</ArticleId><ArticleId IdType="pmc">PMC4738005</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Canada</li><li>États-Unis</li></country><region><li>District de Dresde</li><li>Manitoba</li><li>Ontario</li><li>Saxe (Land)</li><li>Texas</li></region><settlement><li>Austin (Texas)</li><li>Dresde</li><li>Saskatchewan</li><li>Toronto</li></settlement><orgName><li>Université de Regina</li><li>Université de Toronto</li><li>Université du Texas à Austin</li></orgName></list><tree><country name="Canada"><region name="Ontario"><name sortKey="Phanse, Sadhna" sort="Phanse, Sadhna" uniqKey="Phanse S" first="Sadhna" last="Phanse">Sadhna Phanse</name></region><name sortKey="Babu, Mohan" sort="Babu, Mohan" uniqKey="Babu M" first="Mohan" last="Babu">Mohan Babu</name><name sortKey="Bezginov, Alexandr" sort="Bezginov, Alexandr" uniqKey="Bezginov A" first="Alexandr" last="Bezginov">Alexandr Bezginov</name><name sortKey="Borgeson, Blake" sort="Borgeson, Blake" uniqKey="Borgeson B" first="Blake" last="Borgeson">Blake Borgeson</name><name sortKey="Chessman, Kyle" sort="Chessman, Kyle" uniqKey="Chessman K" first="Kyle" last="Chessman">Kyle Chessman</name><name sortKey="Clark, Greg" sort="Clark, Greg" uniqKey="Clark G" first="Greg" last="Clark">Greg Clark</name><name sortKey="Cromar, Graham" sort="Cromar, Graham" uniqKey="Cromar G" first="Graham" last="Cromar">Graham Cromar</name><name sortKey="Derry, W Brent" sort="Derry, W Brent" uniqKey="Derry W" first="W Brent" last="Derry">W Brent Derry</name><name sortKey="Emili, Andrew" sort="Emili, Andrew" uniqKey="Emili A" first="Andrew" last="Emili">Andrew Emili</name><name sortKey="Greenblatt, Jack" sort="Greenblatt, Jack" uniqKey="Greenblatt J" first="Jack" last="Greenblatt">Jack Greenblatt</name><name sortKey="Guo, Xinghua" sort="Guo, Xinghua" uniqKey="Guo X" first="Xinghua" last="Guo">Xinghua Guo</name><name sortKey="Havugimana, Pierre C" sort="Havugimana, Pierre C" uniqKey="Havugimana P" first="Pierre C" last="Havugimana">Pierre C. Havugimana</name><name sortKey="Kagan, Olga" sort="Kagan, Olga" uniqKey="Kagan O" first="Olga" last="Kagan">Olga Kagan</name><name sortKey="Kwan, Julian" sort="Kwan, Julian" uniqKey="Kwan J" first="Julian" last="Kwan">Julian Kwan</name><name sortKey="Malty, Ramy H" sort="Malty, Ramy H" uniqKey="Malty R" first="Ramy H" last="Malty">Ramy H. Malty</name><name sortKey="Ni, Zuyao" sort="Ni, Zuyao" uniqKey="Ni Z" first="Zuyao" last="Ni">Zuyao Ni</name><name sortKey="Pal, Swati" sort="Pal, Swati" uniqKey="Pal S" first="Swati" last="Pal">Swati Pal</name><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name><name sortKey="Stoilova, Snejana" sort="Stoilova, Snejana" uniqKey="Stoilova S" first="Snejana" last="Stoilova">Snejana Stoilova</name><name sortKey="Tillier, Elisabeth R" sort="Tillier, Elisabeth R" uniqKey="Tillier E" first="Elisabeth R" last="Tillier">Elisabeth R. Tillier</name><name sortKey="Xiong, Xuejian" sort="Xiong, Xuejian" uniqKey="Xiong X" first="Xuejian" last="Xiong">Xuejian Xiong</name></country><country name="États-Unis"><region name="Texas"><name sortKey="Wan, Cuihong" sort="Wan, Cuihong" uniqKey="Wan C" first="Cuihong" last="Wan">Cuihong Wan</name></region><name sortKey="Boutz, Daniel R" sort="Boutz, Daniel R" uniqKey="Boutz D" first="Daniel R" last="Boutz">Daniel R. Boutz</name><name sortKey="Drew, Kevin" sort="Drew, Kevin" uniqKey="Drew K" first="Kevin" last="Drew">Kevin Drew</name><name sortKey="Marcotte, Edward M" sort="Marcotte, Edward M" uniqKey="Marcotte E" first="Edward M" last="Marcotte">Edward M. Marcotte</name><name sortKey="Papoulas, Ophelia" sort="Papoulas, Ophelia" uniqKey="Papoulas O" first="Ophelia" last="Papoulas">Ophelia Papoulas</name><name sortKey="Tu, Fan" sort="Tu, Fan" uniqKey="Tu F" first="Fan" last="Tu">Fan Tu</name><name sortKey="Wallingford, John B" sort="Wallingford, John B" uniqKey="Wallingford J" first="John B" last="Wallingford">John B. Wallingford</name></country><country name="Allemagne"><region name="Saxe (Land)"><name sortKey="Sarov, Mihail" sort="Sarov, Mihail" uniqKey="Sarov M" first="Mihail" last="Sarov">Mihail Sarov</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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