Increased Prevalence of Non-motor Symptoms in Essential Tremor
Identifieur interne : 000B46 ( Pmc/Curation ); précédent : 000B45; suivant : 000B47Increased Prevalence of Non-motor Symptoms in Essential Tremor
Auteurs : Annie Lacerte [Canada] ; Sylvain Chouinard [Canada] ; Nicolas Jodoin [Canada] ; Geneviève Bernard [Canada] ; Guy A. Rouleau [Canada] ; Michel Panisset [Canada]Source :
- Tremor and Other Hyperkinetic Movements [ 2160-8288 ] ; 2014.
Abstract
Cases with essential tremor (ET) have been described with Lewy body inclusions, the hallmark of Parkinson disease (PD). Patients with PD may suffer from anosmia, depression, constipation, and rapid eye movement sleep behavior disorder (RBD), sometimes years before the appearance of their motor syndrome. The objective of this study was to evaluate the prevalence of these non-motor Parkinson's associated symptoms in patients with ET.
Fifty ET subjects were contacted by phone and given questionnaires evaluating the presence or absence of anosmia, depression, constipation, and RBD. Frequencies of these symptoms were compared with their published prevalence in the general population.
Of the patients with ET, 4.5% reported having anosmia or hyposmia and 21.7% reported being constipated, similar to what is observed in the general population. Using a screening questionnaire for RBD, 43.5% of ET patients are possibly suffering from RBD, whereas in the general population prevalence is estimated to be 0.5%. Finally, depression was detected in 21.7% of ET patients; in the general population, prevalence is 5%.
Patients with ET seem to have more RBD and more depression than found in the general population. Prospective studies with normal control groups are needed to confirm these findings.
Url:
DOI: 10.7916/D82V2D91
PubMed: 25247108
PubMed Central: 4159683
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Rouleau</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>André-Barbeau Movement Disorders Unit Service of Neurology, Centre Hospitalier de l’Université de Montréal and Department of Medicine, Université de Montréal, Montréal, Québec, Canada</addr-line></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>André-Barbeau Movement Disorders Unit Service of Neurology, Centre Hospitalier de l’Université de Montréal and Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>CENUM, Centre de recherche du Centre Hospitalier de l’Université de Montréal, Québec, Canada</addr-line></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>CENUM, Centre de recherche du Centre Hospitalier de l’Université de Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Panisset, Michel" sort="Panisset, Michel" uniqKey="Panisset M" first="Michel" last="Panisset">Michel Panisset</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>André-Barbeau Movement Disorders Unit Service of Neurology, Centre Hospitalier de l’Université de Montréal and Department of Medicine, Université de Montréal, Montréal, Québec, Canada</addr-line></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>André-Barbeau Movement Disorders Unit Service of Neurology, Centre Hospitalier de l’Université de Montréal and Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation></author></analytic><series><title level="j">Tremor and Other Hyperkinetic Movements</title><idno type="eISSN">2160-8288</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Cases with essential tremor (ET) have been described with Lewy body inclusions, the hallmark of Parkinson disease (PD). Patients with PD may suffer from anosmia, depression, constipation, and rapid eye movement sleep behavior disorder (RBD), sometimes years before the appearance of their motor syndrome. The objective of this study was to evaluate the prevalence of these non-motor Parkinson's associated symptoms in patients with ET.</p></sec><sec><title>Methods</title><p>Fifty ET subjects were contacted by phone and given questionnaires evaluating the presence or absence of anosmia, depression, constipation, and RBD. Frequencies of these symptoms were compared with their published prevalence in the general population.</p></sec><sec><title>Results</title><p>Of the patients with ET, 4.5% reported having anosmia or hyposmia and 21.7% reported being constipated, similar to what is observed in the general population. Using a screening questionnaire for RBD, 43.5% of ET patients are possibly suffering from RBD, whereas in the general population prevalence is estimated to be 0.5%. Finally, depression was detected in 21.7% of ET patients; in the general population, prevalence is 5%.</p></sec><sec><title>Discussion</title><p>Patients with ET seem to have more RBD and more depression than found in the general population. Prospective studies with normal control groups are needed to confirm these findings.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Benito Leon, J" uniqKey="Benito Leon J">J Benito-Leon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benito Leon, J" uniqKey="Benito Leon J">J Benito-Leon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bermejo Pareja, F" uniqKey="Bermejo Pareja F">F Bermejo-Pareja</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koller, Wc" uniqKey="Koller W">WC Koller</name></author><author><name sortKey="Rubino, Fa" uniqKey="Rubino F">FA Rubino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajput, Ah" uniqKey="Rajput A">AH Rajput</name></author><author><name sortKey="Rozdilsky, B" uniqKey="Rozdilsky B">B Rozdilsky</name></author><author><name sortKey="Ang, L" uniqKey="Ang L">L Ang</name></author><author><name sortKey="Rajput, A" uniqKey="Rajput A">A Rajput</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cohen, O" uniqKey="Cohen O">O Cohen</name></author><author><name sortKey="Pullman, S" uniqKey="Pullman S">S Pullman</name></author><author><name sortKey="Jurewicz, E" uniqKey="Jurewicz E">E Jurewicz</name></author><author><name sortKey="Watner, D" uniqKey="Watner D">D Watner</name></author><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chouinard, S" uniqKey="Chouinard S">S Chouinard</name></author><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author><author><name sortKey="Fahn, S" uniqKey="Fahn S">S Fahn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jain, S" uniqKey="Jain S">S Jain</name></author><author><name sortKey="Lo, Se" uniqKey="Lo S">SE Lo</name></author><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benito Leon, J" uniqKey="Benito Leon J">J Benito-Leon</name></author><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Applegate, Lm" uniqKey="Applegate L">LM Applegate</name></author><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author><author><name sortKey="Rios, E" uniqKey="Rios E">E Rios</name></author><author><name sortKey="Pellegrino, Km" uniqKey="Pellegrino K">KM Pellegrino</name></author><author><name sortKey="Jiang, W" uniqKey="Jiang W">W Jiang</name></author><author><name sortKey="Factor Litvak, P" uniqKey="Factor Litvak P">P Factor-Litvak</name></author><author><name sortKey="Zheng, W" uniqKey="Zheng W">W Zheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quagliato, L" uniqKey="Quagliato L">L Quagliato</name></author><author><name sortKey="Viana, M" uniqKey="Viana M">M Viana</name></author><author><name sortKey="Quagliato, E" uniqKey="Quagliato E">E Quagliato</name></author><author><name sortKey="Simis, S" uniqKey="Simis S">S Simis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shah, M" uniqKey="Shah M">M Shah</name></author><author><name sortKey="Muhammed, N" uniqKey="Muhammed N">N Muhammed</name></author><author><name sortKey="Findley, Lj" uniqKey="Findley L">LJ Findley</name></author><author><name sortKey="Hawkes, Ch" uniqKey="Hawkes C">CH Hawkes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Busenbark, Kl" uniqKey="Busenbark K">KL Busenbark</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Miller, Km" uniqKey="Miller K">KM Miller</name></author><author><name sortKey="Okun, Ms" uniqKey="Okun M">MS Okun</name></author><author><name sortKey="Fernandez, Hf" uniqKey="Fernandez H">HF Fernandez</name></author><author><name sortKey="Jacobson, Ce" uniqKey="Jacobson C">CE Jacobson</name></author><author><name sortKey="Rodriguez, Rl" uniqKey="Rodriguez R">RL Rodriguez</name></author><author><name sortKey="Bowers, D" uniqKey="Bowers D">D Bowers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author><author><name sortKey="Benito Leon, J" uniqKey="Benito Leon J">J Benito-Leon</name></author><author><name sortKey="Bermejo Pareja, F" uniqKey="Bermejo Pareja F">F Bermejo-Pareja</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dogu, O" uniqKey="Dogu O">O Dogu</name></author><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author><author><name sortKey="Sevim, S" uniqKey="Sevim S">S Sevim</name></author><author><name sortKey="Kaleagasi, H" uniqKey="Kaleagasi H">H Kaleagasi</name></author><author><name sortKey="Aral, M" uniqKey="Aral M">M Aral</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adler, Ch" uniqKey="Adler C">CH Adler</name></author><author><name sortKey="Hentz, Jg" uniqKey="Hentz J">JG Hentz</name></author><author><name sortKey="Shill, Ha" uniqKey="Shill H">HA Shill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koller, Wc" uniqKey="Koller W">WC Koller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lou, Js" uniqKey="Lou J">JS Lou</name></author><author><name sortKey="Jankovic, J" uniqKey="Jankovic J">J Jankovic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geraghty, Jj" uniqKey="Geraghty J">JJ Geraghty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benito Leon, J" uniqKey="Benito Leon J">J Benito-Leon</name></author><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author><author><name sortKey="Bermejo Pareja, F" uniqKey="Bermejo Pareja F">F Bermejo-Pareja</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vilari O Guell, C" uniqKey="Vilari O Guell C">C Vilariño-Güell</name></author><author><name sortKey="Ross, Oa" uniqKey="Ross O">OA Ross</name></author><author><name sortKey="Wider, C" uniqKey="Wider C">C Wider</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haubenberger, D" uniqKey="Haubenberger D">D Haubenberger</name></author><author><name sortKey="Hotzy, C" uniqKey="Hotzy C">C Hotzy</name></author><author><name sortKey="Pirker, W" uniqKey="Pirker W">W Pirker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Findley, Lj" uniqKey="Findley L">LJ Findley</name></author><author><name sortKey="Koller, Wc" uniqKey="Koller W">WC Koller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stiasny Kolster, K" uniqKey="Stiasny Kolster K">K Stiasny-Kolster</name></author><author><name sortKey="Mayer, G" uniqKey="Mayer G">G Mayer</name></author><author><name sortKey="Sch Fer, S" uniqKey="Sch Fer S">S Schäfer</name></author><author><name sortKey="Moller, Jc" uniqKey="Moller J">JC Möller</name></author><author><name sortKey="Heinzel Gutenbrunner, M" uniqKey="Heinzel Gutenbrunner M">M Heinzel-Gutenbrunner</name></author><author><name sortKey="Oertel, Wh" uniqKey="Oertel W">WH Oertel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suares, Nc" uniqKey="Suares N">NC Suares</name></author><author><name sortKey="Ford, Ac" uniqKey="Ford A">AC Ford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thompson, Aw" uniqKey="Thompson A">AW Thompson</name></author><author><name sortKey="Liu, H" uniqKey="Liu H">H Liu</name></author><author><name sortKey="Hays, Rd" uniqKey="Hays R">RD Hays</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tumas, V" uniqKey="Tumas V">V Tumas</name></author><author><name sortKey="Rodrigues, Gg" uniqKey="Rodrigues G">GG Rodrigues</name></author><author><name sortKey="Farias, Tl" uniqKey="Farias T">TL Farias</name></author><author><name sortKey="Crippa, Ja" uniqKey="Crippa J">JA Crippa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schrag, A" uniqKey="Schrag A">A Schrag</name></author><author><name sortKey="Barone, P" uniqKey="Barone P">P Barone</name></author><author><name sortKey="Brown, Rg" uniqKey="Brown R">RG Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mullol, J" uniqKey="Mullol J">J Mullol</name></author><author><name sortKey="Alobid, I" uniqKey="Alobid I">I Alobid</name></author><author><name sortKey="Marino Snachez, F" uniqKey="Marino Snachez F">F Marino-Snachez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ohayon, Mm" uniqKey="Ohayon M">MM Ohayon</name></author><author><name sortKey="Caulet, M" uniqKey="Caulet M">M Caulet</name></author><author><name sortKey="Priest, Rg" uniqKey="Priest R">RG Priest</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rihmer, Z" uniqKey="Rihmer Z">Z Rihmer</name></author><author><name sortKey="Angst, J" uniqKey="Angst J">J Angst</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gagnon, Jf" uniqKey="Gagnon J">JF Gagnon</name></author><author><name sortKey="Bedard, Ma" uniqKey="Bedard M">MA Bedard</name></author><author><name sortKey="Fantini, Ml" uniqKey="Fantini M">ML Fantini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gjerstad, Md" uniqKey="Gjerstad M">MD Gjerstad</name></author><author><name sortKey="Boeve, B" uniqKey="Boeve B">B Boeve</name></author><author><name sortKey="Wentzel Larsen, T" uniqKey="Wentzel Larsen T">T Wentzel-Larsen</name></author><author><name sortKey="Aarsland, D" uniqKey="Aarsland D">D Aarsland</name></author><author><name sortKey="Larsen, Jp" uniqKey="Larsen J">JP Larsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Plazzi, G" uniqKey="Plazzi G">G Plazzi</name></author><author><name sortKey="Corsini, R" uniqKey="Corsini R">R Corsini</name></author><author><name sortKey="Provini, F" uniqKey="Provini F">F Provini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mckinnon, J" uniqKey="Mckinnon J">J McKinnon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author><author><name sortKey="Jurewicz, Ec" uniqKey="Jurewicz E">EC Jurewicz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louis, Ed" uniqKey="Louis E">ED Louis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doty, Rl" uniqKey="Doty R">RL Doty</name></author><author><name sortKey="Shaman, P" uniqKey="Shaman P">P Shaman</name></author><author><name sortKey="Dann, M" uniqKey="Dann M">M Dann</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Tremor Other Hyperkinet Mov (N Y)</journal-id><journal-id journal-id-type="iso-abbrev">Tremor Other Hyperkinet Mov (N Y)</journal-id><journal-id journal-id-type="publisher-id">TOHM</journal-id><journal-title-group><journal-title>Tremor and Other Hyperkinetic Movements</journal-title></journal-title-group><issn pub-type="epub">2160-8288</issn><publisher><publisher-name>Columbia University Libraries/Information Services</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25247108</article-id><article-id pub-id-type="pmc">4159683</article-id><article-id pub-id-type="doi">10.7916/D82V2D91</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Increased Prevalence of Non-motor Symptoms in Essential Tremor</article-title><alt-title alt-title-type="running-head">Non-motor Symptoms in Essential Tremor</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Lacerte</surname><given-names>Annie</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Chouinard</surname><given-names>Sylvain</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Jodoin</surname><given-names>Nicolas</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Bernard</surname><given-names>Geneviève</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Rouleau</surname><given-names>Guy A.</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Panisset</surname><given-names>Michel</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>André-Barbeau Movement Disorders Unit Service of Neurology, Centre Hospitalier de l’Université de Montréal and Department of Medicine, Université de Montréal, Montréal, Québec, Canada</addr-line></aff><aff id="aff2"><label>2</label><addr-line>Division of Pediatric Neurology, Montreal Children Hospital, McGill University, Québec, Canada</addr-line></aff><aff id="aff3"><label>3</label><addr-line>CENUM, Centre de recherche du Centre Hospitalier de l’Université de Montréal, Québec, Canada</addr-line></aff><contrib-group><contrib contrib-type="editor"><name><surname>Louis</surname><given-names>Elan D.</given-names></name></contrib></contrib-group><aff id="edit1"><addr-line>Columbia University, USA</addr-line></aff><author-notes><corresp id="cor1">*To whom correspondence should be addressed. E-mail: <email>michel.panisset@umontreal.ca</email></corresp></author-notes><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>2</day><month>9</month><year>2014</year></pub-date><volume>4</volume><elocation-id>162</elocation-id><history><date date-type="received"><day>27</day><month>2</month><year>2013</year></date><date date-type="accepted"><day>12</day><month>8</month><year>2014</year></date></history><permissions><copyright-year>2014</copyright-year><copyright-holder>Lacerte et al</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/us/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommerical–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original author and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed.</license-p></license></permissions><abstract><sec><title>Background</title><p>Cases with essential tremor (ET) have been described with Lewy body inclusions, the hallmark of Parkinson disease (PD). Patients with PD may suffer from anosmia, depression, constipation, and rapid eye movement sleep behavior disorder (RBD), sometimes years before the appearance of their motor syndrome. The objective of this study was to evaluate the prevalence of these non-motor Parkinson's associated symptoms in patients with ET.</p></sec><sec><title>Methods</title><p>Fifty ET subjects were contacted by phone and given questionnaires evaluating the presence or absence of anosmia, depression, constipation, and RBD. Frequencies of these symptoms were compared with their published prevalence in the general population.</p></sec><sec><title>Results</title><p>Of the patients with ET, 4.5% reported having anosmia or hyposmia and 21.7% reported being constipated, similar to what is observed in the general population. Using a screening questionnaire for RBD, 43.5% of ET patients are possibly suffering from RBD, whereas in the general population prevalence is estimated to be 0.5%. Finally, depression was detected in 21.7% of ET patients; in the general population, prevalence is 5%.</p></sec><sec><title>Discussion</title><p>Patients with ET seem to have more RBD and more depression than found in the general population. Prospective studies with normal control groups are needed to confirm these findings.</p></sec></abstract><kwd-group><kwd>Essential tremor</kwd><kwd>depression</kwd><kwd>constipation</kwd><kwd>rapid eye movement sleep behavior disorder</kwd><kwd>anosmia</kwd></kwd-group><counts><page-count count="5"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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