La maladie de Parkinson au Canada (serveur d'exploration)

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<title xml:lang="en">A cross-sectional study investigating clinical predictors and physical experiences of pain in Parkinson’s disease</title>
<author>
<name sortKey="Rana, Abdul Qayyum" sort="Rana, Abdul Qayyum" uniqKey="Rana A" first="Abdul Qayyum" last="Rana">Abdul Qayyum Rana</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
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<author>
<name sortKey="Saeed, Usman" sort="Saeed, Usman" uniqKey="Saeed U" first="Usman" last="Saeed">Usman Saeed</name>
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<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
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<affiliation>
<nlm:aff id="af2-297-304">Department of Biological Sciences, University of Toronto, Canada</nlm:aff>
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<author>
<name sortKey="Masroor, Mohamed Sufian" sort="Masroor, Mohamed Sufian" uniqKey="Masroor M" first="Mohamed Sufian" last="Masroor">Mohamed Sufian Masroor</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
</affiliation>
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<author>
<name sortKey="Yousuf, Muhammad Saad" sort="Yousuf, Muhammad Saad" uniqKey="Yousuf M" first="Muhammad Saad" last="Yousuf">Muhammad Saad Yousuf</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Siddiqui, Ishraq" sort="Siddiqui, Ishraq" uniqKey="Siddiqui I" first="Ishraq" last="Siddiqui">Ishraq Siddiqui</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
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<title xml:lang="en" level="a" type="main">A cross-sectional study investigating clinical predictors and physical experiences of pain in Parkinson’s disease</title>
<author>
<name sortKey="Rana, Abdul Qayyum" sort="Rana, Abdul Qayyum" uniqKey="Rana A" first="Abdul Qayyum" last="Rana">Abdul Qayyum Rana</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Saeed, Usman" sort="Saeed, Usman" uniqKey="Saeed U" first="Usman" last="Saeed">Usman Saeed</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="af2-297-304">Department of Biological Sciences, University of Toronto, Canada</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Masroor, Mohamed Sufian" sort="Masroor, Mohamed Sufian" uniqKey="Masroor M" first="Mohamed Sufian" last="Masroor">Mohamed Sufian Masroor</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Yousuf, Muhammad Saad" sort="Yousuf, Muhammad Saad" uniqKey="Yousuf M" first="Muhammad Saad" last="Yousuf">Muhammad Saad Yousuf</name>
<affiliation>
<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Siddiqui, Ishraq" sort="Siddiqui, Ishraq" uniqKey="Siddiqui I" first="Ishraq" last="Siddiqui">Ishraq Siddiqui</name>
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<nlm:aff id="af1-297-304">Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</nlm:aff>
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<series>
<title level="j">Functional Neurology</title>
<idno type="ISSN">0393-5264</idno>
<idno type="eISSN">1971-3274</idno>
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<date when="2014">2014</date>
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<div type="abstract" xml:lang="en">
<title>Summary</title>
<p>Pain is a non-motor symptom of Parkinson’s disease (PD) that is often neglected due to its high prevalence in both the PD and the normal elderly population. The aims of this cross-sectional study were to establish the prevalence of pain, investigate its clinical predictors and analyze physical experiences of pain as described by PD patients.</p>
<p>A total of 121 patients diagnosed with PD were included. The patients underwent a neurological examination and a structured interview and completed questionnaires focusing on clinical types and physical experiences of pain. Logistic regressions were used to analyze possible predictors.</p>
<p>Pain was reported by 80 (66%) patients with a mean age at PD diagnosis of 67.26±11.43 years. The most common clinical types of pain experienced by the patients were dystonic pain (48%), paresthesia/neuropathic pain (36%) and musculoskeletal pain (28%). The PD patients described their physical experience of pain as aching (46%), a feeling of tension (18%), sharp pain (12%), deep pain (12%) and dull pain (11%). Patients with PD affecting the right side of the body were four times more likely to report pain on the right side of the body; however, no such relation was found for the left side of the body. A higher UPDRS-III scale score and longer PD duration reduced the likelihood of patients reporting dull pain. The presence of paresthesia/neuropathic pain was shown to decrease the likelihood of patients reporting sharp pain. No significant relationships were found between the magnitude of pain and gender, age at PD diagnosis, PD duration, UPDRS-III score, or Hoehn and Yahr stage of PD. Although 40% of the PD patients felt that medication had a (direct) effect on their pain, no relationship could be found between pain severity and PD medication.</p>
</div>
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<journal-id journal-id-type="nlm-ta">Funct Neurol</journal-id>
<journal-id journal-id-type="publisher-id">Functional Neurology</journal-id>
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<journal-title>Functional Neurology</journal-title>
</journal-title-group>
<issn pub-type="ppub">0393-5264</issn>
<issn pub-type="epub">1971-3274</issn>
<publisher>
<publisher-name>CIC Edizioni Internationali</publisher-name>
</publisher>
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<article-id pub-id-type="pmid">24598399</article-id>
<article-id pub-id-type="pmc">3951259</article-id>
<article-id pub-id-type="publisher-id">297-304</article-id>
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<subject>Articles</subject>
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<article-title>A cross-sectional study investigating clinical predictors and physical experiences of pain in Parkinson’s disease</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Rana</surname>
<given-names>Abdul Qayyum</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="af1-297-304">
<sup>a</sup>
</xref>
<xref ref-type="corresp" rid="c1-297-304"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Saeed</surname>
<given-names>Usman</given-names>
</name>
<degrees>BSc (Hons)</degrees>
<xref ref-type="aff" rid="af1-297-304">
<sup>a</sup>
</xref>
<xref ref-type="aff" rid="af2-297-304">
<sup>b</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Masroor</surname>
<given-names>Mohamed Sufian</given-names>
</name>
<degrees>BSc (Hons)</degrees>
<xref ref-type="aff" rid="af1-297-304">
<sup>a</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Yousuf</surname>
<given-names>Muhammad Saad</given-names>
</name>
<degrees>BSc (Hons)</degrees>
<xref ref-type="aff" rid="af1-297-304">
<sup>a</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Siddiqui</surname>
<given-names>Ishraq</given-names>
</name>
<degrees>BSc (Hons)</degrees>
<xref ref-type="aff" rid="af1-297-304">
<sup>a</sup>
</xref>
</contrib>
</contrib-group>
<aff id="af1-297-304">
<label>a</label>
Parkinson’s Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Canada</aff>
<aff id="af2-297-304">
<label>b</label>
Department of Biological Sciences, University of Toronto, Canada</aff>
<author-notes>
<corresp id="c1-297-304">Correspondence to: Abdul Qayyum Rana E-mail:
<email>ranaaq@yahoo.com</email>
</corresp>
</author-notes>
<pub-date pub-type="collection">
<season>Oct-Dec</season>
<year>2013</year>
</pub-date>
<pub-date pub-type="epub">
<day>5</day>
<month>3</month>
<year>2014</year>
</pub-date>
<volume>28</volume>
<issue>4</issue>
<fpage>297</fpage>
<lpage>304</lpage>
<permissions>
<copyright-statement>Copyright ©2013, CIC Edizioni Internazionali</copyright-statement>
<copyright-year>2013</copyright-year>
</permissions>
<abstract>
<title>Summary</title>
<p>Pain is a non-motor symptom of Parkinson’s disease (PD) that is often neglected due to its high prevalence in both the PD and the normal elderly population. The aims of this cross-sectional study were to establish the prevalence of pain, investigate its clinical predictors and analyze physical experiences of pain as described by PD patients.</p>
<p>A total of 121 patients diagnosed with PD were included. The patients underwent a neurological examination and a structured interview and completed questionnaires focusing on clinical types and physical experiences of pain. Logistic regressions were used to analyze possible predictors.</p>
<p>Pain was reported by 80 (66%) patients with a mean age at PD diagnosis of 67.26±11.43 years. The most common clinical types of pain experienced by the patients were dystonic pain (48%), paresthesia/neuropathic pain (36%) and musculoskeletal pain (28%). The PD patients described their physical experience of pain as aching (46%), a feeling of tension (18%), sharp pain (12%), deep pain (12%) and dull pain (11%). Patients with PD affecting the right side of the body were four times more likely to report pain on the right side of the body; however, no such relation was found for the left side of the body. A higher UPDRS-III scale score and longer PD duration reduced the likelihood of patients reporting dull pain. The presence of paresthesia/neuropathic pain was shown to decrease the likelihood of patients reporting sharp pain. No significant relationships were found between the magnitude of pain and gender, age at PD diagnosis, PD duration, UPDRS-III score, or Hoehn and Yahr stage of PD. Although 40% of the PD patients felt that medication had a (direct) effect on their pain, no relationship could be found between pain severity and PD medication.</p>
</abstract>
<kwd-group>
<kwd>non-motor symptoms</kwd>
<kwd>pain</kwd>
<kwd>Parkinson disease</kwd>
</kwd-group>
</article-meta>
</front>
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