Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
Identifieur interne : 000642 ( Pmc/Checkpoint ); précédent : 000641; suivant : 000643Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
Auteurs : Jennifer Permuth-Wey ; Kate Lawrenson ; Howard C. Shen ; Aneliya Velkova ; Jonathan P. Tyrer [Royaume-Uni] ; Zhihua Chen ; Hui-Yi Lin ; Y. Ann Chen ; Ya-Yu Tsai ; Xiaotao Qu ; Susan J. Ramus ; Rod Karevan ; Janet Lee ; Nathan Lee ; Melissa C. Larson ; Katja K. Aben [Pays-Bas] ; Hoda Anton-Culver ; Natalia Antonenkova [Biélorussie] ; Antonis Antoniou [Royaume-Uni] ; Sebastian M. Armasu ; François Bacot ; Laura Baglietto [Australie] ; Elisa V. Bandera ; Jill Barnholtz-Sloan ; Matthias W. Beckmann [Allemagne] ; Michael J. Birrer ; Greg Bloom ; Natalia Bogdanova [Allemagne] ; Louise A. Brinton ; Angela Brooks-Wilson ; Robert Brown [Royaume-Uni] ; Ralf Butzow ; Qiuyin Cai ; Ian Campbell [Australie] ; Jenny Chang-Claude [Allemagne] ; Stephen Chanock ; Georgia Chenevix-Trench [Australie] ; Jin Q. Cheng ; Mine S. Cicek ; Gerhard A. Coetzee [États-Unis] ; Linda S. Cook ; Fergus J. Couch ; Daniel W. Cramer ; Julie M. Cunningham ; Agnieszka Dansonka-Mieszkowska ; Evelyn Despierre ; Jennifer A. Doherty ; Thilo Dörk [Allemagne] ; Andreas Du Bois [Allemagne] ; Matthias Dürst [Allemagne] ; Douglas F. Easton [Royaume-Uni] ; Diana Eccles [Royaume-Uni] ; Robert Edwards ; Arif B. Ekici [Allemagne] ; Peter A. Fasching [Allemagne] ; David A. Fenstermacher ; James M. Flanagan [Royaume-Uni] ; Montserrat Garcia-Closas ; Aleksandra Gentry-Maharaj [Royaume-Uni] ; Graham G. Giles [Australie] ; Rosalind M. Glasspool [Royaume-Uni] ; Jesus Gonzalez-Bosquet ; Marc T. Goodman ; Martin Gore [Royaume-Uni] ; Bohdan G Rski ; Jacek Gronwald ; Per Hall ; Mari K. Halle [Norvège] ; Philipp Harter [Allemagne] ; Florian Heitz [Allemagne] ; Peter Hillemanns [Allemagne] ; Maureen Hoatlin ; Claus K. H Gdall [Danemark] ; Estrid H Gdall [Danemark] ; Satoyo Hosono [Japon] ; Anna Jakubowska ; Allan Jensen [Danemark] ; Heather Jim ; Kimberly R. Kalli ; Beth Y. Karlan ; Stanley B. Kaye [Royaume-Uni] ; Linda E. Kelemen [Canada] ; Lambertus A. Kiemeney [Pays-Bas] ; Fumitaka Kikkawa [Japon] ; Gottfried E. Konecny ; Camilla Krakstad [Norvège] ; Susanne Krüger Kjaer [Danemark] ; Jolanta Kupryjanczyk ; Diether Lambrechts [Belgique] ; Sandrina Lambrechts ; Johnathan M. Lancaster ; Nhu D. Le ; Arto Leminen ; Douglas A. Levine ; Dong Liang ; Boon Kiong Lim [Malaisie] ; Jie Lin ; Jolanta Lissowska [Pologne] ; Karen H. Lu ; Jan Lubi Ski ; Galina Lurie ; Leon F. A. G. Massuger [Pays-Bas] ; Keitaro Matsuo [Japon] ; Valerie Mcguire ; John R. Mclaughlin [Canada] ; Usha Menon [Royaume-Uni] ; Francesmary Modugno ; Kirsten B. Moysich ; Toru Nakanishi [Japon] ; Steven A. Narod [Canada] ; Lotte Nedergaard [Danemark] ; Roberta B. Ness ; Heli Nevanlinna ; Stefan Nickels [Allemagne] ; Houtan Noushmehr [États-Unis] ; Kunle Odunsi ; Sara H. Olson ; Irene Orlow ; James Paul [Royaume-Uni] ; Celeste L. Pearce ; Tanja Pejovic ; Liisa M. Pelttari ; Malcolm C. Pike ; Elizabeth M. Poole ; Paola Raska ; Stefan P. Renner [Allemagne] ; Harvey A. Risch ; Lorna Rodriguez-Rodriguez ; Mary Anne Rossing [États-Unis] ; Anja Rudolph [Allemagne] ; Ingo B. Runnebaum [Allemagne] ; Iwona K. Rzepecka ; Helga B. Salvesen [Norvège] ; Ira Schwaab [Allemagne] ; Gianluca Severi [Australie] ; Vijayalakshmi Shridhar ; Xiao-Ou Shu ; Yurii B. Shvetsov ; Weiva Sieh ; Honglin Song [Royaume-Uni] ; Melissa C. Southey [Australie] ; Beata Spiewankiewicz ; Daniel Stram ; Rebecca Sutphen [États-Unis] ; Soo-Hwang Teo [Malaisie] ; Kathryn L. Terry ; Daniel C. Tessier ; Pamela J. Thompson ; Shelley S. Tworoger ; Anne M. Van Altena [Pays-Bas] ; Ignace Vergote ; Robert A. Vierkant ; Daniel Vincent ; Allison F. Vitonis ; Shan Wang-Gohrke [Allemagne] ; Rachel Palmieri Weber ; Nicolas Wentzensen ; Alice S. Whittemore ; Elisabeth Wik [Norvège] ; Lynne R. Wilkens ; Boris Winterhoff ; Yin Ling Woo [Malaisie] ; Anna H. Wu ; Yong-Bing Xiang ; Hannah P. Yang ; Wei Zheng ; Argyrios Ziogas ; Famida Zulkifli [Malaisie] ; Catherine M. Phelan ; Edwin Iversen ; Joellen M. Schildkraut ; Andrew Berchuck ; Brooke L. Fridley ; Ellen L. Goode ; Paul D. P. Pharoah [Royaume-Uni] ; Alvaro N. A. Monteiro ; Thomas A. Sellers ; Simon A. GaytherSource :
- Nature communications [ 2041-1723 ] ; 2013.
Abstract
Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3′ untranslated region at putative microRNA (miRNA) binding sites represent functional targets that influence EOC susceptibility. Here, we evaluate the association between 767 miRNA binding site single nucleotide polymorphisms (miRSNPs) and EOC risk in 18,174 EOC cases and 26,134 controls from 43 studies genotyped through the Collaborative Oncological Gene-environment Study. We identify several miRSNPs associated with invasive serous EOC risk (OR=1.12,
Url:
DOI: 10.1038/ncomms2613
PubMed: 23535648
PubMed Central: 3709460
Affiliations:
- Allemagne, Australie, Belgique, Biélorussie, Canada, Danemark, Japon, Malaisie, Norvège, Pays-Bas, Pologne, Royaume-Uni, États-Unis
- Alberta, Angleterre, Angleterre de l'Est, Bade-Wurtemberg, Basse-Saxe, Bavière, Californie, District de Karlsruhe, District de Moyenne-Franconie, District de Tübingen, Floride, Hovedstaden, Ontario, Washington (État)
- Calgary, Cambridge, Copenhague, Erlangen, Hanovre, Heidelberg, Los Angeles, Seattle, Tampa, Toronto, Ulm
- Université d'Ulm, Université de Calgary, Université de Californie du Sud, Université de Cambridge, Université de Floride du Sud, Université de Toronto, Université de Washington
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Shen</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Velkova, Aneliya" sort="Velkova, Aneliya" uniqKey="Velkova A" first="Aneliya" last="Velkova">Aneliya Velkova</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Tyrer, Jonathan P" sort="Tyrer, Jonathan P" uniqKey="Tyrer J" first="Jonathan P." last="Tyrer">Jonathan P. Tyrer</name><affiliation wicri:level="4"><nlm:aff id="A3">Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Chen, Zhihua" sort="Chen, Zhihua" uniqKey="Chen Z" first="Zhihua" last="Chen">Zhihua Chen</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Lin, Hui Yi" sort="Lin, Hui Yi" uniqKey="Lin H" first="Hui-Yi" last="Lin">Hui-Yi Lin</name><affiliation><nlm:aff id="A5">Department of Biostatistics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Chen, Y Ann" sort="Chen, Y Ann" uniqKey="Chen Y" first="Y. Ann" last="Chen">Y. Ann Chen</name><affiliation><nlm:aff id="A5">Department of Biostatistics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Tsai, Ya Yu" sort="Tsai, Ya Yu" uniqKey="Tsai Y" first="Ya-Yu" last="Tsai">Ya-Yu Tsai</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Qu, Xiaotao" sort="Qu, Xiaotao" uniqKey="Qu X" first="Xiaotao" last="Qu">Xiaotao Qu</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J." last="Ramus">Susan J. Ramus</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Karevan, Rod" sort="Karevan, Rod" uniqKey="Karevan R" first="Rod" last="Karevan">Rod Karevan</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Lee, Janet" sort="Lee, Janet" uniqKey="Lee J" first="Janet" last="Lee">Janet Lee</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Lee, Nathan" sort="Lee, Nathan" uniqKey="Lee N" first="Nathan" last="Lee">Nathan Lee</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Larson, Melissa C" sort="Larson, Melissa C" uniqKey="Larson M" first="Melissa C." last="Larson">Melissa C. Larson</name><affiliation><nlm:aff id="A6">Department of Health Science Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Aben, Katja K" sort="Aben, Katja K" uniqKey="Aben K" first="Katja K." last="Aben">Katja K. Aben</name><affiliation wicri:level="1"><nlm:aff id="A7">Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A8">Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX</wicri:regionArea><wicri:noRegion>1066CX</wicri:noRegion></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="A9">Department of Epidemiology, Director of Genetic Epidemiology Research Institute, UCI Center of Medicine, University of California Irvine, Irvine, CA, USA, 92697</nlm:aff><wicri:noCountry code="subfield">92697</wicri:noCountry></affiliation></author><author><name sortKey="Antonenkova, Natalia" sort="Antonenkova, Natalia" uniqKey="Antonenkova N" first="Natalia" last="Antonenkova">Natalia Antonenkova</name><affiliation wicri:level="1"><nlm:aff id="A10">Byelorussian Institute for Oncology and Medical Radiology Aleksandrov N.N., 223040, Minsk, Belarus</nlm:aff><country xml:lang="fr">Biélorussie</country><wicri:regionArea>Byelorussian Institute for Oncology and Medical Radiology Aleksandrov N.N., 223040, Minsk</wicri:regionArea><wicri:noRegion>Minsk</wicri:noRegion></affiliation></author><author><name sortKey="Antoniou, Antonis" sort="Antoniou, Antonis" uniqKey="Antoniou A" first="Antonis" last="Antoniou">Antonis Antoniou</name><affiliation wicri:level="4"><nlm:aff id="A11">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Armasu, Sebastian M" sort="Armasu, Sebastian M" uniqKey="Armasu S" first="Sebastian M." last="Armasu">Sebastian M. Armasu</name><affiliation><nlm:aff id="A6">Department of Health Science Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Bacot, Francois" sort="Bacot, Francois" uniqKey="Bacot F" first="François" last="Bacot">François Bacot</name><affiliation><nlm:aff id="A14">McGill University and Génome Québec Innovation Centre, Montréal (Québec) Canada, H3A 0G1</nlm:aff><wicri:noCountry code="subfield">H3A 0G1</wicri:noCountry></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="1"><nlm:aff id="A15">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053</wicri:regionArea><wicri:noRegion>Carlton VIC 3053</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea><wicri:noRegion>VIC 3010</wicri:noRegion></affiliation></author><author><name sortKey="Bandera, Elisa V" sort="Bandera, Elisa V" uniqKey="Bandera E" first="Elisa V." last="Bandera">Elisa V. Bandera</name><affiliation><nlm:aff id="A17">The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA, 08901</nlm:aff><wicri:noCountry code="subfield">08901</wicri:noCountry></affiliation></author><author><name sortKey="Barnholtz Sloan, Jill" sort="Barnholtz Sloan, Jill" uniqKey="Barnholtz Sloan J" first="Jill" last="Barnholtz-Sloan">Jill Barnholtz-Sloan</name><affiliation><nlm:aff id="A18">Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA, 44195</nlm:aff><wicri:noCountry code="subfield">44195</wicri:noCountry></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="1"><nlm:aff id="A19">University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054</wicri:regionArea><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion></affiliation></author><author><name sortKey="Birrer, Michael J" sort="Birrer, Michael J" uniqKey="Birrer M" first="Michael J." last="Birrer">Michael J. Birrer</name><affiliation><nlm:aff id="A20">Massachusetts General Hospital, Boston, MA, USA, 02114</nlm:aff><wicri:noCountry code="subfield">02114</wicri:noCountry></affiliation></author><author><name sortKey="Bloom, Greg" sort="Bloom, Greg" uniqKey="Bloom G" first="Greg" last="Bloom">Greg Bloom</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Bogdanova, Natalia" sort="Bogdanova, Natalia" uniqKey="Bogdanova N" first="Natalia" last="Bogdanova">Natalia Bogdanova</name><affiliation wicri:level="3"><nlm:aff id="A21">Gynaecology Research Unit, Hannover Medical School, Hannover, 30625, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover, 30625</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Brinton, Louise A" sort="Brinton, Louise A" uniqKey="Brinton L" first="Louise A." last="Brinton">Louise A. Brinton</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Brooks Wilson, Angela" sort="Brooks Wilson, Angela" uniqKey="Brooks Wilson A" first="Angela" last="Brooks-Wilson">Angela Brooks-Wilson</name><affiliation><nlm:aff id="A23">Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada, V5Z 1L3</nlm:aff><wicri:noCountry code="subfield">V5Z 1L3</wicri:noCountry></affiliation></author><author><name sortKey="Brown, Robert" sort="Brown, Robert" uniqKey="Brown R" first="Robert" last="Brown">Robert Brown</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ</wicri:regionArea><wicri:noRegion>SW7 2AZ</wicri:noRegion></affiliation></author><author><name sortKey="Butzow, Ralf" sort="Butzow, Ralf" uniqKey="Butzow R" first="Ralf" last="Butzow">Ralf Butzow</name><affiliation><nlm:aff id="A25">Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Cai, Qiuyin" sort="Cai, Qiuyin" uniqKey="Cai Q" first="Qiuyin" last="Cai">Qiuyin Cai</name><affiliation><nlm:aff id="A27">Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA, 37232</nlm:aff><wicri:noCountry code="subfield">37232</wicri:noCountry></affiliation></author><author><name sortKey="Campbell, Ian" sort="Campbell, Ian" uniqKey="Campbell I" first="Ian" last="Campbell">Ian Campbell</name><affiliation wicri:level="1"><nlm:aff id="A13">Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3002, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3002</wicri:regionArea><wicri:noRegion>VIC 3002</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Department of Pathology, University of Melbourne, Parkville, VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, University of Melbourne, Parkville, VIC 3053</wicri:regionArea><wicri:noRegion>VIC 3053</wicri:noRegion></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="3"><nlm:aff id="A29">German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Chanock, Stephen" sort="Chanock, Stephen" uniqKey="Chanock S" first="Stephen" last="Chanock">Stephen Chanock</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:aff id="A12">Queensland Institute of Medical Research, Brisbane QLD 4006, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane QLD 4006</wicri:regionArea><wicri:noRegion>Brisbane QLD 4006</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Jin Q" sort="Cheng, Jin Q" uniqKey="Cheng J" first="Jin Q." last="Cheng">Jin Q. Cheng</name><affiliation><nlm:aff id="A30">Department of Interdisciplinary Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Cicek, Mine S" sort="Cicek, Mine S" uniqKey="Cicek M" first="Mine S." last="Cicek">Mine S. Cicek</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Coetzee, Gerhard A" sort="Coetzee, Gerhard A" uniqKey="Coetzee G" first="Gerhard A." last="Coetzee">Gerhard A. Coetzee</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Urology, Microbiology and Preventive Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90089</nlm:aff><orgName type="university">Université de Californie du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cook, Linda S" sort="Cook, Linda S" uniqKey="Cook L" first="Linda S." last="Cook">Linda S. Cook</name><affiliation><nlm:aff id="A35">Division Epidemiology and Biostatistics, University of New Mexico, Albuquerque, NM, USA, 87131</nlm:aff><wicri:noCountry code="subfield">87131</wicri:noCountry></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation><nlm:aff id="A34">Department of Laboratory of Medicine and Pathology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Cramer, Daniel W" sort="Cramer, Daniel W" uniqKey="Cramer D" first="Daniel W." last="Cramer">Daniel W. Cramer</name><affiliation><nlm:aff id="A36">Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Cunningham, Julie M" sort="Cunningham, Julie M" uniqKey="Cunningham J" first="Julie M." last="Cunningham">Julie M. Cunningham</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Dansonka Mieszkowska, Agnieszka" sort="Dansonka Mieszkowska, Agnieszka" uniqKey="Dansonka Mieszkowska A" first="Agnieszka" last="Dansonka-Mieszkowska">Agnieszka Dansonka-Mieszkowska</name><affiliation><nlm:aff id="A37">Department of Molecular Pathology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Despierre, Evelyn" sort="Despierre, Evelyn" uniqKey="Despierre E" first="Evelyn" last="Despierre">Evelyn Despierre</name><affiliation><nlm:aff id="A38">Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium, 3000</nlm:aff><wicri:noCountry code="subfield">3000</wicri:noCountry></affiliation></author><author><name sortKey="Doherty, Jennifer A" sort="Doherty, Jennifer A" uniqKey="Doherty J" first="Jennifer A" last="Doherty">Jennifer A. Doherty</name><affiliation><nlm:aff id="A39">Section of Biostatistics and Epidemiology, The Geisel School of Medicine at Dartmouth, Lebanon, NH, USA, 03755</nlm:aff><wicri:noCountry code="subfield">03755</wicri:noCountry></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="3"><nlm:aff id="A21">Gynaecology Research Unit, Hannover Medical School, Hannover, 30625, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover, 30625</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Du Bois, Andreas" sort="Du Bois, Andreas" uniqKey="Du Bois A" first="Andreas" last="Du Bois">Andreas Du Bois</name><affiliation wicri:level="1"><nlm:aff id="A40">Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden</wicri:regionArea><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen</wicri:regionArea><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Durst, Matthias" sort="Durst, Matthias" uniqKey="Durst M" first="Matthias" last="Dürst">Matthias Dürst</name><affiliation wicri:level="1"><nlm:aff id="A42">Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena</wicri:regionArea><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation wicri:level="4"><nlm:aff id="A11">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><affiliation wicri:level="1"><nlm:aff id="A44">Faculty of Medicine, University of Southampton, University Hospital Southampton, SO17 1BJ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Faculty of Medicine, University of Southampton, University Hospital Southampton, SO17 1BJ</wicri:regionArea><wicri:noRegion>SO17 1BJ</wicri:noRegion></affiliation></author><author><name sortKey="Edwards, Robert" sort="Edwards, Robert" uniqKey="Edwards R" first="Robert" last="Edwards">Robert Edwards</name><affiliation><nlm:aff id="A45">Maggee Women's Hospital, Pittsburg, PA, USA, 15213</nlm:aff><wicri:noCountry code="subfield">15213</wicri:noCountry></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation wicri:level="3"><nlm:aff id="A46">Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation wicri:level="1"><nlm:aff id="A19">University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054</wicri:regionArea><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion></affiliation><affiliation><nlm:aff id="A47">Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA, 90095</nlm:aff><wicri:noCountry code="subfield">90095</wicri:noCountry></affiliation></author><author><name sortKey="Fenstermacher, David A" sort="Fenstermacher, David A" uniqKey="Fenstermacher D" first="David A." last="Fenstermacher">David A. Fenstermacher</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Flanagan, James M" sort="Flanagan, James M" uniqKey="Flanagan J" first="James M." last="Flanagan">James M. Flanagan</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ</wicri:regionArea><wicri:noRegion>SW7 2AZ</wicri:noRegion></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="A48">Sections of Epidemiology and Genetics at the Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, UK, SW7 3RP</nlm:aff><wicri:noCountry code="subfield">SW7 3RP</wicri:noCountry></affiliation></author><author><name sortKey="Gentry Maharaj, Aleksandra" sort="Gentry Maharaj, Aleksandra" uniqKey="Gentry Maharaj A" first="Aleksandra" last="Gentry-Maharaj">Aleksandra Gentry-Maharaj</name><affiliation wicri:level="1"><nlm:aff id="A49">Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU</wicri:regionArea><wicri:noRegion>NW1 2BU</wicri:noRegion></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation wicri:level="1"><nlm:aff id="A15">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053</wicri:regionArea><wicri:noRegion>Carlton VIC 3053</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea><wicri:noRegion>VIC 3010</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC 3806, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC 3806</wicri:regionArea><wicri:noRegion>VIC 3806</wicri:noRegion></affiliation></author><author><name sortKey="Glasspool, Rosalind M" sort="Glasspool, Rosalind M" uniqKey="Glasspool R" first="Rosalind M." last="Glasspool">Rosalind M. Glasspool</name><affiliation wicri:level="1"><nlm:aff id="A51">The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN</wicri:regionArea><wicri:noRegion>G12 0YN</wicri:noRegion></affiliation></author><author><name sortKey="Gonzalez Bosquet, Jesus" sort="Gonzalez Bosquet, Jesus" uniqKey="Gonzalez Bosquet J" first="Jesus" last="Gonzalez-Bosquet">Jesus Gonzalez-Bosquet</name><affiliation><nlm:aff id="A52">Department of Women's Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Goodman, Marc T" sort="Goodman, Marc T" uniqKey="Goodman M" first="Marc T." last="Goodman">Marc T. Goodman</name><affiliation><nlm:aff id="A53">Samuel Oschin Comprehensive Cancer Center Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA, 90048</nlm:aff><wicri:noCountry code="subfield">90048</wicri:noCountry></affiliation></author><author><name sortKey="Gore, Martin" sort="Gore, Martin" uniqKey="Gore M" first="Martin" last="Gore">Martin Gore</name><affiliation wicri:level="1"><nlm:aff id="A54">Gynecological Oncology Unit, The Royal Marsden Hospital, London, SW3 6JJ, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Gynecological Oncology Unit, The Royal Marsden Hospital, London, SW3 6JJ</wicri:regionArea><wicri:noRegion>SW3 6JJ</wicri:noRegion></affiliation></author><author><name sortKey="G Rski, Bohdan" sort="G Rski, Bohdan" uniqKey="G Rski B" first="Bohdan" last="G Rski">Bohdan G Rski</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A56">Department of Epidemiology and Biostatistics, Karolinska Istitutet, Stockholm, Sweden, 171-77</nlm:aff><wicri:noCountry code="subfield">171-77</wicri:noCountry></affiliation></author><author><name sortKey="Halle, Mari K" sort="Halle, Mari K" uniqKey="Halle M" first="Mari K." last="Halle">Mari K. Halle</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Harter, Philipp" sort="Harter, Philipp" uniqKey="Harter P" first="Philipp" last="Harter">Philipp Harter</name><affiliation wicri:level="1"><nlm:aff id="A40">Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden</wicri:regionArea><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen</wicri:regionArea><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Heitz, Florian" sort="Heitz, Florian" uniqKey="Heitz F" first="Florian" last="Heitz">Florian Heitz</name><affiliation wicri:level="1"><nlm:aff id="A40">Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden</wicri:regionArea><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen</wicri:regionArea><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation wicri:level="3"><nlm:aff id="A59">Clinics of Obstetrics and Gynaecology, Hannover Medical School, 30625, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Clinics of Obstetrics and Gynaecology, Hannover Medical School, 30625, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Hoatlin, Maureen" sort="Hoatlin, Maureen" uniqKey="Hoatlin M" first="Maureen" last="Hoatlin">Maureen Hoatlin</name><affiliation><nlm:aff id="A60">Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, OR, USA, 97239</nlm:aff><wicri:noCountry code="subfield">97239</wicri:noCountry></affiliation></author><author><name sortKey="H Gdall, Claus K" sort="H Gdall, Claus K" uniqKey="H Gdall C" first="Claus K." last="H Gdall">Claus K. H Gdall</name><affiliation wicri:level="1"><nlm:aff id="A61">The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100</wicri:regionArea><wicri:noRegion>2100</wicri:noRegion></affiliation></author><author><name sortKey="H Gdall, Estrid" sort="H Gdall, Estrid" uniqKey="H Gdall E" first="Estrid" last="H Gdall">Estrid H Gdall</name><affiliation><nlm:aff id="A62">Department of Pathology, Molecular Unit, Herlev Hospital, University of Copenhagen, Denmark, 2730</nlm:aff><wicri:noCountry code="subfield">2730</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:aff id="A63">Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Hosono, Satoyo" sort="Hosono, Satoyo" uniqKey="Hosono S" first="Satoyo" last="Hosono">Satoyo Hosono</name><affiliation wicri:level="1"><nlm:aff id="A64">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681</wicri:regionArea><wicri:noRegion>464-8681</wicri:noRegion></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Jensen, Allan" sort="Jensen, Allan" uniqKey="Jensen A" first="Allan" last="Jensen">Allan Jensen</name><affiliation wicri:level="3"><nlm:aff id="A63">Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Jim, Heather" sort="Jim, Heather" uniqKey="Jim H" first="Heather" last="Jim">Heather Jim</name><affiliation><nlm:aff id="A65">Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Kalli, Kimberly R" sort="Kalli, Kimberly R" uniqKey="Kalli K" first="Kimberly R." last="Kalli">Kimberly R. Kalli</name><affiliation><nlm:aff id="A66">Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name><affiliation><nlm:aff id="A67">Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA, 90048</nlm:aff><wicri:noCountry code="subfield">90048</wicri:noCountry></affiliation></author><author><name sortKey="Kaye, Stanley B" sort="Kaye, Stanley B" uniqKey="Kaye S" first="Stanley B." last="Kaye">Stanley B. Kaye</name><affiliation wicri:level="1"><nlm:aff id="A68">Section of Medicine, Institute of Cancer Research, Sutton, SM2 5NG, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Medicine, Institute of Cancer Research, Sutton, SM2 5NG</wicri:regionArea><wicri:noRegion>SM2 5NG</wicri:noRegion></affiliation></author><author><name sortKey="Kelemen, Linda E" sort="Kelemen, Linda E" uniqKey="Kelemen L" first="Linda E." last="Kelemen">Linda E. Kelemen</name><affiliation wicri:level="4"><nlm:aff id="A69">Department of Popluation Health Research, Alberta Health Services-Cancer Care, Calgary, Alberta, Canada and Departments of Medical Genetics and Oncology, University of Calgary, Calgary, AB, Canada, T2N 2T9</nlm:aff><orgName type="university">Université de Calgary</orgName><country>Canada</country><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Kiemeney, Lambertus A" sort="Kiemeney, Lambertus A" uniqKey="Kiemeney L" first="Lambertus A." last="Kiemeney">Lambertus A. Kiemeney</name><affiliation wicri:level="1"><nlm:aff id="A7">Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A8">Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX</wicri:regionArea><wicri:noRegion>1066CX</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A70">Department of Urology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Urology, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation></author><author><name sortKey="Kikkawa, Fumitaka" sort="Kikkawa, Fumitaka" uniqKey="Kikkawa F" first="Fumitaka" last="Kikkawa">Fumitaka Kikkawa</name><affiliation wicri:level="1"><nlm:aff id="A71">Department of Obsterics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Obsterics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550</wicri:regionArea><wicri:noRegion>466-8550</wicri:noRegion></affiliation></author><author><name sortKey="Konecny, Gottfried E" sort="Konecny, Gottfried E" uniqKey="Konecny G" first="Gottfried E." last="Konecny">Gottfried E. Konecny</name><affiliation><nlm:aff id="A47">Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA, 90095</nlm:aff><wicri:noCountry code="subfield">90095</wicri:noCountry></affiliation></author><author><name sortKey="Krakstad, Camilla" sort="Krakstad, Camilla" uniqKey="Krakstad C" first="Camilla" last="Krakstad">Camilla Krakstad</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Kjaer, Susanne Kruger" sort="Kjaer, Susanne Kruger" uniqKey="Kjaer S" first="Susanne Krüger" last="Kjaer">Susanne Krüger Kjaer</name><affiliation wicri:level="1"><nlm:aff id="A61">The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100</wicri:regionArea><wicri:noRegion>2100</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A63">Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Kupryjanczyk, Jolanta" sort="Kupryjanczyk, Jolanta" uniqKey="Kupryjanczyk J" first="Jolanta" last="Kupryjanczyk">Jolanta Kupryjanczyk</name><affiliation><nlm:aff id="A37">Department of Molecular Pathology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><nlm:aff id="A72">Vesalius Research Center, VIB, 3000, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center, VIB, 3000, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A73">Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Lambrechts, Sandrina" sort="Lambrechts, Sandrina" uniqKey="Lambrechts S" first="Sandrina" last="Lambrechts">Sandrina Lambrechts</name><affiliation><nlm:aff id="A38">Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium, 3000</nlm:aff><wicri:noCountry code="subfield">3000</wicri:noCountry></affiliation></author><author><name sortKey="Lancaster, Johnathan M" sort="Lancaster, Johnathan M" uniqKey="Lancaster J" first="Johnathan M." last="Lancaster">Johnathan M. Lancaster</name><affiliation><nlm:aff id="A52">Department of Women's Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Le, Nhu D" sort="Le, Nhu D" uniqKey="Le N" first="Nhu D." last="Le">Nhu D. Le</name><affiliation><nlm:aff id="A74">Cancer Control Research, BC Cancer Agency, Vancouver, BC, Canada, G12 0YN</nlm:aff><wicri:noCountry code="subfield">G12 0YN</wicri:noCountry></affiliation></author><author><name sortKey="Leminen, Arto" sort="Leminen, Arto" uniqKey="Leminen A" first="Arto" last="Leminen">Arto Leminen</name><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Levine, Douglas A" sort="Levine, Douglas A" uniqKey="Levine D" first="Douglas A." last="Levine">Douglas A. Levine</name><affiliation><nlm:aff id="A75">Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10021</nlm:aff><wicri:noCountry code="subfield">10021</wicri:noCountry></affiliation></author><author><name sortKey="Liang, Dong" sort="Liang, Dong" uniqKey="Liang D" first="Dong" last="Liang">Dong Liang</name><affiliation><nlm:aff id="A76">College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA, 77044</nlm:aff><wicri:noCountry code="subfield">77044</wicri:noCountry></affiliation></author><author><name sortKey="Lim, Boon Kiong" sort="Lim, Boon Kiong" uniqKey="Lim B" first="Boon Kiong" last="Lim">Boon Kiong Lim</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Jie" sort="Lin, Jie" uniqKey="Lin J" first="Jie" last="Lin">Jie Lin</name><affiliation><nlm:aff id="A78">Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation wicri:level="1"><nlm:aff id="A79">Department of Cancer Epidemiology and Prevention, The Maria Sklodowska-Curie Memorial Cancer Center, 02-781, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Cancer Epidemiology and Prevention, The Maria Sklodowska-Curie Memorial Cancer Center, 02-781, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Karen H" sort="Lu, Karen H" uniqKey="Lu K" first="Karen H." last="Lu">Karen H. Lu</name><affiliation><nlm:aff id="A80">Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation></author><author><name sortKey="Lubi Ski, Jan" sort="Lubi Ski, Jan" uniqKey="Lubi Ski J" first="Jan" last="Lubi Ski">Jan Lubi Ski</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Lurie, Galina" sort="Lurie, Galina" uniqKey="Lurie G" first="Galina" last="Lurie">Galina Lurie</name><affiliation><nlm:aff id="A81">Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA, 96813</nlm:aff><wicri:noCountry code="subfield">96813</wicri:noCountry></affiliation></author><author><name sortKey="Massuger, Leon F A G" sort="Massuger, Leon F A G" uniqKey="Massuger L" first="Leon F. A. G." last="Massuger">Leon F. A. G. Massuger</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation></author><author><name sortKey="Matsuo, Keitaro" sort="Matsuo, Keitaro" uniqKey="Matsuo K" first="Keitaro" last="Matsuo">Keitaro Matsuo</name><affiliation wicri:level="1"><nlm:aff id="A64">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681</wicri:regionArea><wicri:noRegion>464-8681</wicri:noRegion></affiliation></author><author><name sortKey="Mcguire, Valerie" sort="Mcguire, Valerie" uniqKey="Mcguire V" first="Valerie" last="Mcguire">Valerie Mcguire</name><affiliation><nlm:aff id="A83">Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford CA, USA, 94305</nlm:aff><wicri:noCountry code="subfield">94305</wicri:noCountry></affiliation></author><author><name sortKey="Mclaughlin, John R" sort="Mclaughlin, John R" uniqKey="Mclaughlin J" first="John R" last="Mclaughlin">John R. Mclaughlin</name><affiliation wicri:level="4"><nlm:aff id="A84">Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, ON, M5T 3M7, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, ON, M5T 3M7</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation><nlm:aff id="A85">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, M5G 1X5</nlm:aff><wicri:noCountry code="subfield">M5G 1X5</wicri:noCountry></affiliation></author><author><name sortKey="Menon, Usha" sort="Menon, Usha" uniqKey="Menon U" first="Usha" last="Menon">Usha Menon</name><affiliation wicri:level="1"><nlm:aff id="A49">Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU</wicri:regionArea><wicri:noRegion>NW1 2BU</wicri:noRegion></affiliation></author><author><name sortKey="Modugno, Francesmary" sort="Modugno, Francesmary" uniqKey="Modugno F" first="Francesmary" last="Modugno">Francesmary Modugno</name><affiliation><nlm:aff id="A78">Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation><affiliation><nlm:aff id="A80">Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation><affiliation><nlm:aff id="A86">Women's Cancer Research Program, Magee-Womens Research Institute and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA, 15213</nlm:aff><wicri:noCountry code="subfield">15213</wicri:noCountry></affiliation></author><author><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B." last="Moysich">Kirsten B. Moysich</name><affiliation><nlm:aff id="A87">Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA, 14263</nlm:aff><wicri:noCountry code="subfield">14263</wicri:noCountry></affiliation></author><author><name sortKey="Nakanishi, Toru" sort="Nakanishi, Toru" uniqKey="Nakanishi T" first="Toru" last="Nakanishi">Toru Nakanishi</name><affiliation wicri:level="1"><nlm:aff id="A88">Department of Gynecologic Oncology, Aichi Cancer Center Central Hospital, Nagoya, Aichi, Nagoya, 464-8681, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Gynecologic Oncology, Aichi Cancer Center Central Hospital, Nagoya, Aichi, Nagoya, 464-8681</wicri:regionArea><wicri:noRegion>464-8681</wicri:noRegion></affiliation></author><author><name sortKey="Narod, Steven A" sort="Narod, Steven A" uniqKey="Narod S" first="Steven A." last="Narod">Steven A. Narod</name><affiliation wicri:level="4"><nlm:aff id="A89">Women's College Research Institute, University of Toronto, Toronto, Ontario, Canada, M5G 1N8</nlm:aff><orgName type="university">Université de Toronto</orgName><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Nedergaard, Lotte" sort="Nedergaard, Lotte" uniqKey="Nedergaard L" first="Lotte" last="Nedergaard">Lotte Nedergaard</name><affiliation wicri:level="1"><nlm:aff id="A90">Department of Pathology, Rigshospitalet, University of Copenhagen, 2100, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Pathology, Rigshospitalet, University of Copenhagen, 2100</wicri:regionArea><wicri:noRegion>2100</wicri:noRegion></affiliation></author><author><name sortKey="Ness, Roberta B" sort="Ness, Roberta B" uniqKey="Ness R" first="Roberta B." last="Ness">Roberta B. Ness</name><affiliation><nlm:aff id="A91">The University of Texas School of Public Health, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation wicri:level="3"><nlm:aff id="A29">German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Noushmehr, Houtan" sort="Noushmehr, Houtan" uniqKey="Noushmehr H" first="Houtan" last="Noushmehr">Houtan Noushmehr</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Urology, Microbiology and Preventive Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90089</nlm:aff><orgName type="university">Université de Californie du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A92">USC Epigenome Center, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, 90089</nlm:aff><orgName type="university">Université de Californie du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Odunsi, Kunle" sort="Odunsi, Kunle" uniqKey="Odunsi K" first="Kunle" last="Odunsi">Kunle Odunsi</name><affiliation><nlm:aff id="A93">Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA, 14263</nlm:aff><wicri:noCountry code="subfield">14263</wicri:noCountry></affiliation></author><author><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H." last="Olson">Sara H. Olson</name><affiliation><nlm:aff id="A94">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10065</nlm:aff><wicri:noCountry code="subfield">10065</wicri:noCountry></affiliation></author><author><name sortKey="Orlow, Irene" sort="Orlow, Irene" uniqKey="Orlow I" first="Irene" last="Orlow">Irene Orlow</name><affiliation><nlm:aff id="A94">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10065</nlm:aff><wicri:noCountry code="subfield">10065</wicri:noCountry></affiliation></author><author><name sortKey="Paul, James" sort="Paul, James" uniqKey="Paul J" first="James" last="Paul">James Paul</name><affiliation wicri:level="1"><nlm:aff id="A51">The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN</wicri:regionArea><wicri:noRegion>G12 0YN</wicri:noRegion></affiliation></author><author><name sortKey="Pearce, Celeste L" sort="Pearce, Celeste L" uniqKey="Pearce C" first="Celeste L" last="Pearce">Celeste L. Pearce</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Pejovic, Tanja" sort="Pejovic, Tanja" uniqKey="Pejovic T" first="Tanja" last="Pejovic">Tanja Pejovic</name><affiliation><nlm:aff id="A95">Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA, 97239</nlm:aff><wicri:noCountry code="subfield">97239</wicri:noCountry></affiliation><affiliation><nlm:aff id="A96">Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA, 97239</nlm:aff><wicri:noCountry code="subfield">97239</wicri:noCountry></affiliation></author><author><name sortKey="Pelttari, Liisa M" sort="Pelttari, Liisa M" uniqKey="Pelttari L" first="Liisa M." last="Pelttari">Liisa M. Pelttari</name><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Pike, Malcolm C" sort="Pike, Malcolm C" uniqKey="Pike M" first="Malcolm C." last="Pike">Malcolm C. Pike</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation><affiliation><nlm:aff id="A94">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10065</nlm:aff><wicri:noCountry code="subfield">10065</wicri:noCountry></affiliation></author><author><name sortKey="Poole, Elizabeth M" sort="Poole, Elizabeth M" uniqKey="Poole E" first="Elizabeth M." last="Poole">Elizabeth M. Poole</name><affiliation><nlm:aff id="A97">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation><affiliation><nlm:aff id="A98">Channing Laboratory, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Raska, Paola" sort="Raska, Paola" uniqKey="Raska P" first="Paola" last="Raska">Paola Raska</name><affiliation><nlm:aff id="A18">Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA, 44195</nlm:aff><wicri:noCountry code="subfield">44195</wicri:noCountry></affiliation></author><author><name sortKey="Renner, Stefan P" sort="Renner, Stefan P" uniqKey="Renner S" first="Stefan P." last="Renner">Stefan P. Renner</name><affiliation wicri:level="1"><nlm:aff id="A19">University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054</wicri:regionArea><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion></affiliation></author><author><name sortKey="Risch, Harvey A" sort="Risch, Harvey A" uniqKey="Risch H" first="Harvey A." last="Risch">Harvey A. Risch</name><affiliation><nlm:aff id="A99">Department of Epidemiology and Public Health, Yale University School of Public Health and School of Medicine, New Haven, CT, USA, 06520</nlm:aff><wicri:noCountry code="subfield">06520</wicri:noCountry></affiliation></author><author><name sortKey="Rodriguez Rodriguez, Lorna" sort="Rodriguez Rodriguez, Lorna" uniqKey="Rodriguez Rodriguez L" first="Lorna" last="Rodriguez-Rodriguez">Lorna Rodriguez-Rodriguez</name><affiliation><nlm:aff id="A17">The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA, 08901</nlm:aff><wicri:noCountry code="subfield">08901</wicri:noCountry></affiliation></author><author><name sortKey="Rossing, Mary Anne" sort="Rossing, Mary Anne" uniqKey="Rossing M" first="Mary Anne" last="Rossing">Mary Anne Rossing</name><affiliation><nlm:aff id="A100">Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, 98109</nlm:aff><wicri:noCountry code="subfield">98109</wicri:noCountry></affiliation><affiliation wicri:level="4"><nlm:aff id="A101">Department of Epidemiology, University of Washington, Seattle, WA, USA, 98109</nlm:aff><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation wicri:level="3"><nlm:aff id="A29">German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Runnebaum, Ingo B" sort="Runnebaum, Ingo B" uniqKey="Runnebaum I" first="Ingo B." last="Runnebaum">Ingo B. Runnebaum</name><affiliation wicri:level="1"><nlm:aff id="A42">Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena</wicri:regionArea><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Rzepecka, Iwona K" sort="Rzepecka, Iwona K" uniqKey="Rzepecka I" first="Iwona K." last="Rzepecka">Iwona K. Rzepecka</name><affiliation><nlm:aff id="A37">Department of Molecular Pathology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Salvesen, Helga B" sort="Salvesen, Helga B" uniqKey="Salvesen H" first="Helga B." last="Salvesen">Helga B. Salvesen</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Schwaab, Ira" sort="Schwaab, Ira" uniqKey="Schwaab I" first="Ira" last="Schwaab">Ira Schwaab</name><affiliation wicri:level="1"><nlm:aff id="A102">Institut für Humangenetik Wiesbaden, 65187, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Humangenetik Wiesbaden, 65187, Wiesbaden</wicri:regionArea><wicri:noRegion>65187, Wiesbaden</wicri:noRegion><wicri:noRegion>65187, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="1"><nlm:aff id="A15">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053</wicri:regionArea><wicri:noRegion>Carlton VIC 3053</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea><wicri:noRegion>VIC 3010</wicri:noRegion></affiliation></author><author><name sortKey="Shridhar, Vijayalakshmi" sort="Shridhar, Vijayalakshmi" uniqKey="Shridhar V" first="Vijayalakshmi" last="Shridhar">Vijayalakshmi Shridhar</name><affiliation><nlm:aff id="A103">Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="A27">Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA, 37232</nlm:aff><wicri:noCountry code="subfield">37232</wicri:noCountry></affiliation></author><author><name sortKey="Shvetsov, Yurii B" sort="Shvetsov, Yurii B" uniqKey="Shvetsov Y" first="Yurii B." last="Shvetsov">Yurii B. Shvetsov</name><affiliation><nlm:aff id="A81">Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA, 96813</nlm:aff><wicri:noCountry code="subfield">96813</wicri:noCountry></affiliation></author><author><name sortKey="Sieh, Weiva" sort="Sieh, Weiva" uniqKey="Sieh W" first="Weiva" last="Sieh">Weiva Sieh</name><affiliation><nlm:aff id="A83">Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford CA, USA, 94305</nlm:aff><wicri:noCountry code="subfield">94305</wicri:noCountry></affiliation></author><author><name sortKey="Song, Honglin" sort="Song, Honglin" uniqKey="Song H" first="Honglin" last="Song">Honglin Song</name><affiliation wicri:level="4"><nlm:aff id="A3">Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation wicri:level="1"><nlm:aff id="A104">Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, VIC 3053</wicri:regionArea><wicri:noRegion>VIC 3053</wicri:noRegion></affiliation></author><author><name sortKey="Spiewankiewicz, Beata" sort="Spiewankiewicz, Beata" uniqKey="Spiewankiewicz B" first="Beata" last="Spiewankiewicz">Beata Spiewankiewicz</name><affiliation><nlm:aff id="A105">Department of Gynecologic Oncology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Stram, Daniel" sort="Stram, Daniel" uniqKey="Stram D" first="Daniel" last="Stram">Daniel Stram</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Sutphen, Rebecca" sort="Sutphen, Rebecca" uniqKey="Sutphen R" first="Rebecca" last="Sutphen">Rebecca Sutphen</name><affiliation wicri:level="4"><nlm:aff id="A106">Pediatrics Epidemiology Center, College of Medicine, University of South Florida, Tampa, FL, USA, 33612</nlm:aff><orgName type="university">Université de Floride du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Tampa</settlement><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Terry, Kathryn L" sort="Terry, Kathryn L" uniqKey="Terry K" first="Kathryn L." last="Terry">Kathryn L. Terry</name><affiliation><nlm:aff id="A36">Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Tessier, Daniel C" sort="Tessier, Daniel C" uniqKey="Tessier D" first="Daniel C." last="Tessier">Daniel C. Tessier</name><affiliation><nlm:aff id="A14">McGill University and Génome Québec Innovation Centre, Montréal (Québec) Canada, H3A 0G1</nlm:aff><wicri:noCountry code="subfield">H3A 0G1</wicri:noCountry></affiliation></author><author><name sortKey="Thompson, Pamela J" sort="Thompson, Pamela J" uniqKey="Thompson P" first="Pamela J." last="Thompson">Pamela J. Thompson</name><affiliation><nlm:aff id="A53">Samuel Oschin Comprehensive Cancer Center Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA, 90048</nlm:aff><wicri:noCountry code="subfield">90048</wicri:noCountry></affiliation></author><author><name sortKey="Tworoger, Shelley S" sort="Tworoger, Shelley S" uniqKey="Tworoger S" first="Shelley S." last="Tworoger">Shelley S. Tworoger</name><affiliation><nlm:aff id="A97">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation><affiliation><nlm:aff id="A98">Channing Laboratory, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Van Altena, Anne M" sort="Van Altena, Anne M" uniqKey="Van Altena A" first="Anne M." last="Van Altena">Anne M. Van Altena</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation></author><author><name sortKey="Vergote, Ignace" sort="Vergote, Ignace" uniqKey="Vergote I" first="Ignace" last="Vergote">Ignace Vergote</name><affiliation><nlm:aff id="A38">Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium, 3000</nlm:aff><wicri:noCountry code="subfield">3000</wicri:noCountry></affiliation></author><author><name sortKey="Vierkant, Robert A" sort="Vierkant, Robert A" uniqKey="Vierkant R" first="Robert A." last="Vierkant">Robert A. Vierkant</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Vincent, Daniel" sort="Vincent, Daniel" uniqKey="Vincent D" first="Daniel" last="Vincent">Daniel Vincent</name><affiliation><nlm:aff id="A14">McGill University and Génome Québec Innovation Centre, Montréal (Québec) Canada, H3A 0G1</nlm:aff><wicri:noCountry code="subfield">H3A 0G1</wicri:noCountry></affiliation></author><author><name sortKey="Vitonis, Allison F" sort="Vitonis, Allison F" uniqKey="Vitonis A" first="Allison F." last="Vitonis">Allison F. Vitonis</name><affiliation><nlm:aff id="A36">Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation wicri:level="4"><nlm:aff id="A107">Department of Obstetrics and Gynecology, University of Ulm, Ulm, 89081, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Ulm, Ulm, 89081</wicri:regionArea><wicri:noRegion>89081</wicri:noRegion><orgName type="university">Université d'Ulm</orgName><placeName><settlement type="city">Ulm</settlement><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region></placeName></affiliation></author><author><name sortKey="Weber, Rachel Palmieri" sort="Weber, Rachel Palmieri" uniqKey="Weber R" first="Rachel Palmieri" last="Weber">Rachel Palmieri Weber</name><affiliation><nlm:aff id="A108">Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation></author><author><name sortKey="Wentzensen, Nicolas" sort="Wentzensen, Nicolas" uniqKey="Wentzensen N" first="Nicolas" last="Wentzensen">Nicolas Wentzensen</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Whittemore, Alice S" sort="Whittemore, Alice S" uniqKey="Whittemore A" first="Alice S." last="Whittemore">Alice S. Whittemore</name><affiliation><nlm:aff id="A83">Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford CA, USA, 94305</nlm:aff><wicri:noCountry code="subfield">94305</wicri:noCountry></affiliation></author><author><name sortKey="Wik, Elisabeth" sort="Wik, Elisabeth" uniqKey="Wik E" first="Elisabeth" last="Wik">Elisabeth Wik</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Wilkens, Lynne R" sort="Wilkens, Lynne R" uniqKey="Wilkens L" first="Lynne R." last="Wilkens">Lynne R. Wilkens</name><affiliation><nlm:aff id="A81">Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA, 96813</nlm:aff><wicri:noCountry code="subfield">96813</wicri:noCountry></affiliation></author><author><name sortKey="Winterhoff, Boris" sort="Winterhoff, Boris" uniqKey="Winterhoff B" first="Boris" last="Winterhoff">Boris Winterhoff</name><affiliation><nlm:aff id="A109">Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Woo, Yin Ling" sort="Woo, Yin Ling" uniqKey="Woo Y" first="Yin Ling" last="Woo">Yin Ling Woo</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Anna H" sort="Wu, Anna H" uniqKey="Wu A" first="Anna H." last="Wu">Anna H. Wu</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation><nlm:aff id="A110">Shanghai Cancer Institute, Shanghai, China, 2200-25</nlm:aff><wicri:noCountry code="subfield">2200-25</wicri:noCountry></affiliation></author><author><name sortKey="Yang, Hannah P" sort="Yang, Hannah P" uniqKey="Yang H" first="Hannah P." last="Yang">Hannah P. Yang</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A27">Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA, 37232</nlm:aff><wicri:noCountry code="subfield">37232</wicri:noCountry></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation><nlm:aff id="A111">Department of Epidemiology, Center for Cancer Genetics Research and Prevention, School of Medicine, University of California Irvine, Irvine, California, USA, 92697</nlm:aff><wicri:noCountry code="subfield">92697</wicri:noCountry></affiliation></author><author><name sortKey="Zulkifli, Famida" sort="Zulkifli, Famida" uniqKey="Zulkifli F" first="Famida" last="Zulkifli">Famida Zulkifli</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Phelan, Catherine M" sort="Phelan, Catherine M" uniqKey="Phelan C" first="Catherine M." last="Phelan">Catherine M. Phelan</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Iversen, Edwin" sort="Iversen, Edwin" uniqKey="Iversen E" first="Edwin" last="Iversen">Edwin Iversen</name><affiliation><nlm:aff id="A112">Department of Statistical Science, Duke University, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation></author><author><name sortKey="Schildkraut, Joellen M" sort="Schildkraut, Joellen M" uniqKey="Schildkraut J" first="Joellen M." last="Schildkraut">Joellen M. Schildkraut</name><affiliation><nlm:aff id="A108">Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation><affiliation><nlm:aff id="A113">Cancer Prevention, Detection and Control Research Program, Duke Cancer Institute, Durham, North Carolina, USA, 27708-0251</nlm:aff><wicri:noCountry code="subfield">27708-0251</wicri:noCountry></affiliation></author><author><name sortKey="Berchuck, Andrew" sort="Berchuck, Andrew" uniqKey="Berchuck A" first="Andrew" last="Berchuck">Andrew Berchuck</name><affiliation><nlm:aff id="A114">Department of Obstetrics and Gynecology, Duke Comprehensive Cancer Center, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation></author><author><name sortKey="Fridley, Brooke L" sort="Fridley, Brooke L" uniqKey="Fridley B" first="Brooke L." last="Fridley">Brooke L. Fridley</name><affiliation><nlm:aff id="A115">Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA, 66160</nlm:aff><wicri:noCountry code="subfield">66160</wicri:noCountry></affiliation></author><author><name sortKey="Goode, Ellen L" sort="Goode, Ellen L" uniqKey="Goode E" first="Ellen L." last="Goode">Ellen L. Goode</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="4"><nlm:aff id="A11">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Monteiro, Alvaro N A" sort="Monteiro, Alvaro N A" uniqKey="Monteiro A" first="Alvaro N. A." last="Monteiro">Alvaro N. A. Monteiro</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Sellers, Thomas A" sort="Sellers, Thomas A" uniqKey="Sellers T" first="Thomas A." last="Sellers">Thomas A. Sellers</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Gayther, Simon A" sort="Gayther, Simon A" uniqKey="Gayther S" first="Simon A." last="Gayther">Simon A. Gayther</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23535648</idno><idno type="pmc">3709460</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709460</idno><idno type="RBID">PMC:3709460</idno><idno type="doi">10.1038/ncomms2613</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000B53</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000B53</idno><idno type="wicri:Area/Pmc/Curation">000B53</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000B53</idno><idno type="wicri:Area/Pmc/Checkpoint">000642</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000642</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31</title><author><name sortKey="Permuth Wey, Jennifer" sort="Permuth Wey, Jennifer" uniqKey="Permuth Wey J" first="Jennifer" last="Permuth-Wey">Jennifer Permuth-Wey</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Lawrenson, Kate" sort="Lawrenson, Kate" uniqKey="Lawrenson K" first="Kate" last="Lawrenson">Kate Lawrenson</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Shen, Howard C" sort="Shen, Howard C" uniqKey="Shen H" first="Howard C." last="Shen">Howard C. Shen</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Velkova, Aneliya" sort="Velkova, Aneliya" uniqKey="Velkova A" first="Aneliya" last="Velkova">Aneliya Velkova</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Tyrer, Jonathan P" sort="Tyrer, Jonathan P" uniqKey="Tyrer J" first="Jonathan P." last="Tyrer">Jonathan P. Tyrer</name><affiliation wicri:level="4"><nlm:aff id="A3">Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Chen, Zhihua" sort="Chen, Zhihua" uniqKey="Chen Z" first="Zhihua" last="Chen">Zhihua Chen</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Lin, Hui Yi" sort="Lin, Hui Yi" uniqKey="Lin H" first="Hui-Yi" last="Lin">Hui-Yi Lin</name><affiliation><nlm:aff id="A5">Department of Biostatistics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Chen, Y Ann" sort="Chen, Y Ann" uniqKey="Chen Y" first="Y. Ann" last="Chen">Y. Ann Chen</name><affiliation><nlm:aff id="A5">Department of Biostatistics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Tsai, Ya Yu" sort="Tsai, Ya Yu" uniqKey="Tsai Y" first="Ya-Yu" last="Tsai">Ya-Yu Tsai</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Qu, Xiaotao" sort="Qu, Xiaotao" uniqKey="Qu X" first="Xiaotao" last="Qu">Xiaotao Qu</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J." last="Ramus">Susan J. Ramus</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Karevan, Rod" sort="Karevan, Rod" uniqKey="Karevan R" first="Rod" last="Karevan">Rod Karevan</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Lee, Janet" sort="Lee, Janet" uniqKey="Lee J" first="Janet" last="Lee">Janet Lee</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Lee, Nathan" sort="Lee, Nathan" uniqKey="Lee N" first="Nathan" last="Lee">Nathan Lee</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Larson, Melissa C" sort="Larson, Melissa C" uniqKey="Larson M" first="Melissa C." last="Larson">Melissa C. Larson</name><affiliation><nlm:aff id="A6">Department of Health Science Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Aben, Katja K" sort="Aben, Katja K" uniqKey="Aben K" first="Katja K." last="Aben">Katja K. Aben</name><affiliation wicri:level="1"><nlm:aff id="A7">Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A8">Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX</wicri:regionArea><wicri:noRegion>1066CX</wicri:noRegion></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="A9">Department of Epidemiology, Director of Genetic Epidemiology Research Institute, UCI Center of Medicine, University of California Irvine, Irvine, CA, USA, 92697</nlm:aff><wicri:noCountry code="subfield">92697</wicri:noCountry></affiliation></author><author><name sortKey="Antonenkova, Natalia" sort="Antonenkova, Natalia" uniqKey="Antonenkova N" first="Natalia" last="Antonenkova">Natalia Antonenkova</name><affiliation wicri:level="1"><nlm:aff id="A10">Byelorussian Institute for Oncology and Medical Radiology Aleksandrov N.N., 223040, Minsk, Belarus</nlm:aff><country xml:lang="fr">Biélorussie</country><wicri:regionArea>Byelorussian Institute for Oncology and Medical Radiology Aleksandrov N.N., 223040, Minsk</wicri:regionArea><wicri:noRegion>Minsk</wicri:noRegion></affiliation></author><author><name sortKey="Antoniou, Antonis" sort="Antoniou, Antonis" uniqKey="Antoniou A" first="Antonis" last="Antoniou">Antonis Antoniou</name><affiliation wicri:level="4"><nlm:aff id="A11">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Armasu, Sebastian M" sort="Armasu, Sebastian M" uniqKey="Armasu S" first="Sebastian M." last="Armasu">Sebastian M. Armasu</name><affiliation><nlm:aff id="A6">Department of Health Science Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Bacot, Francois" sort="Bacot, Francois" uniqKey="Bacot F" first="François" last="Bacot">François Bacot</name><affiliation><nlm:aff id="A14">McGill University and Génome Québec Innovation Centre, Montréal (Québec) Canada, H3A 0G1</nlm:aff><wicri:noCountry code="subfield">H3A 0G1</wicri:noCountry></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="1"><nlm:aff id="A15">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053</wicri:regionArea><wicri:noRegion>Carlton VIC 3053</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea><wicri:noRegion>VIC 3010</wicri:noRegion></affiliation></author><author><name sortKey="Bandera, Elisa V" sort="Bandera, Elisa V" uniqKey="Bandera E" first="Elisa V." last="Bandera">Elisa V. Bandera</name><affiliation><nlm:aff id="A17">The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA, 08901</nlm:aff><wicri:noCountry code="subfield">08901</wicri:noCountry></affiliation></author><author><name sortKey="Barnholtz Sloan, Jill" sort="Barnholtz Sloan, Jill" uniqKey="Barnholtz Sloan J" first="Jill" last="Barnholtz-Sloan">Jill Barnholtz-Sloan</name><affiliation><nlm:aff id="A18">Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA, 44195</nlm:aff><wicri:noCountry code="subfield">44195</wicri:noCountry></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="1"><nlm:aff id="A19">University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054</wicri:regionArea><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion></affiliation></author><author><name sortKey="Birrer, Michael J" sort="Birrer, Michael J" uniqKey="Birrer M" first="Michael J." last="Birrer">Michael J. Birrer</name><affiliation><nlm:aff id="A20">Massachusetts General Hospital, Boston, MA, USA, 02114</nlm:aff><wicri:noCountry code="subfield">02114</wicri:noCountry></affiliation></author><author><name sortKey="Bloom, Greg" sort="Bloom, Greg" uniqKey="Bloom G" first="Greg" last="Bloom">Greg Bloom</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Bogdanova, Natalia" sort="Bogdanova, Natalia" uniqKey="Bogdanova N" first="Natalia" last="Bogdanova">Natalia Bogdanova</name><affiliation wicri:level="3"><nlm:aff id="A21">Gynaecology Research Unit, Hannover Medical School, Hannover, 30625, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover, 30625</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Brinton, Louise A" sort="Brinton, Louise A" uniqKey="Brinton L" first="Louise A." last="Brinton">Louise A. Brinton</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Brooks Wilson, Angela" sort="Brooks Wilson, Angela" uniqKey="Brooks Wilson A" first="Angela" last="Brooks-Wilson">Angela Brooks-Wilson</name><affiliation><nlm:aff id="A23">Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada, V5Z 1L3</nlm:aff><wicri:noCountry code="subfield">V5Z 1L3</wicri:noCountry></affiliation></author><author><name sortKey="Brown, Robert" sort="Brown, Robert" uniqKey="Brown R" first="Robert" last="Brown">Robert Brown</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ</wicri:regionArea><wicri:noRegion>SW7 2AZ</wicri:noRegion></affiliation></author><author><name sortKey="Butzow, Ralf" sort="Butzow, Ralf" uniqKey="Butzow R" first="Ralf" last="Butzow">Ralf Butzow</name><affiliation><nlm:aff id="A25">Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Cai, Qiuyin" sort="Cai, Qiuyin" uniqKey="Cai Q" first="Qiuyin" last="Cai">Qiuyin Cai</name><affiliation><nlm:aff id="A27">Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA, 37232</nlm:aff><wicri:noCountry code="subfield">37232</wicri:noCountry></affiliation></author><author><name sortKey="Campbell, Ian" sort="Campbell, Ian" uniqKey="Campbell I" first="Ian" last="Campbell">Ian Campbell</name><affiliation wicri:level="1"><nlm:aff id="A13">Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3002, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3002</wicri:regionArea><wicri:noRegion>VIC 3002</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Department of Pathology, University of Melbourne, Parkville, VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, University of Melbourne, Parkville, VIC 3053</wicri:regionArea><wicri:noRegion>VIC 3053</wicri:noRegion></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="3"><nlm:aff id="A29">German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Chanock, Stephen" sort="Chanock, Stephen" uniqKey="Chanock S" first="Stephen" last="Chanock">Stephen Chanock</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:aff id="A12">Queensland Institute of Medical Research, Brisbane QLD 4006, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane QLD 4006</wicri:regionArea><wicri:noRegion>Brisbane QLD 4006</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Jin Q" sort="Cheng, Jin Q" uniqKey="Cheng J" first="Jin Q." last="Cheng">Jin Q. Cheng</name><affiliation><nlm:aff id="A30">Department of Interdisciplinary Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Cicek, Mine S" sort="Cicek, Mine S" uniqKey="Cicek M" first="Mine S." last="Cicek">Mine S. Cicek</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Coetzee, Gerhard A" sort="Coetzee, Gerhard A" uniqKey="Coetzee G" first="Gerhard A." last="Coetzee">Gerhard A. Coetzee</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Urology, Microbiology and Preventive Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90089</nlm:aff><orgName type="university">Université de Californie du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cook, Linda S" sort="Cook, Linda S" uniqKey="Cook L" first="Linda S." last="Cook">Linda S. Cook</name><affiliation><nlm:aff id="A35">Division Epidemiology and Biostatistics, University of New Mexico, Albuquerque, NM, USA, 87131</nlm:aff><wicri:noCountry code="subfield">87131</wicri:noCountry></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation><nlm:aff id="A34">Department of Laboratory of Medicine and Pathology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Cramer, Daniel W" sort="Cramer, Daniel W" uniqKey="Cramer D" first="Daniel W." last="Cramer">Daniel W. Cramer</name><affiliation><nlm:aff id="A36">Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Cunningham, Julie M" sort="Cunningham, Julie M" uniqKey="Cunningham J" first="Julie M." last="Cunningham">Julie M. Cunningham</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Dansonka Mieszkowska, Agnieszka" sort="Dansonka Mieszkowska, Agnieszka" uniqKey="Dansonka Mieszkowska A" first="Agnieszka" last="Dansonka-Mieszkowska">Agnieszka Dansonka-Mieszkowska</name><affiliation><nlm:aff id="A37">Department of Molecular Pathology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Despierre, Evelyn" sort="Despierre, Evelyn" uniqKey="Despierre E" first="Evelyn" last="Despierre">Evelyn Despierre</name><affiliation><nlm:aff id="A38">Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium, 3000</nlm:aff><wicri:noCountry code="subfield">3000</wicri:noCountry></affiliation></author><author><name sortKey="Doherty, Jennifer A" sort="Doherty, Jennifer A" uniqKey="Doherty J" first="Jennifer A" last="Doherty">Jennifer A. Doherty</name><affiliation><nlm:aff id="A39">Section of Biostatistics and Epidemiology, The Geisel School of Medicine at Dartmouth, Lebanon, NH, USA, 03755</nlm:aff><wicri:noCountry code="subfield">03755</wicri:noCountry></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="3"><nlm:aff id="A21">Gynaecology Research Unit, Hannover Medical School, Hannover, 30625, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover, 30625</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Du Bois, Andreas" sort="Du Bois, Andreas" uniqKey="Du Bois A" first="Andreas" last="Du Bois">Andreas Du Bois</name><affiliation wicri:level="1"><nlm:aff id="A40">Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden</wicri:regionArea><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen</wicri:regionArea><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Durst, Matthias" sort="Durst, Matthias" uniqKey="Durst M" first="Matthias" last="Dürst">Matthias Dürst</name><affiliation wicri:level="1"><nlm:aff id="A42">Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena</wicri:regionArea><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation wicri:level="4"><nlm:aff id="A11">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><affiliation wicri:level="1"><nlm:aff id="A44">Faculty of Medicine, University of Southampton, University Hospital Southampton, SO17 1BJ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Faculty of Medicine, University of Southampton, University Hospital Southampton, SO17 1BJ</wicri:regionArea><wicri:noRegion>SO17 1BJ</wicri:noRegion></affiliation></author><author><name sortKey="Edwards, Robert" sort="Edwards, Robert" uniqKey="Edwards R" first="Robert" last="Edwards">Robert Edwards</name><affiliation><nlm:aff id="A45">Maggee Women's Hospital, Pittsburg, PA, USA, 15213</nlm:aff><wicri:noCountry code="subfield">15213</wicri:noCountry></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation wicri:level="3"><nlm:aff id="A46">Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation wicri:level="1"><nlm:aff id="A19">University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054</wicri:regionArea><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion></affiliation><affiliation><nlm:aff id="A47">Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA, 90095</nlm:aff><wicri:noCountry code="subfield">90095</wicri:noCountry></affiliation></author><author><name sortKey="Fenstermacher, David A" sort="Fenstermacher, David A" uniqKey="Fenstermacher D" first="David A." last="Fenstermacher">David A. Fenstermacher</name><affiliation><nlm:aff id="A4">Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Flanagan, James M" sort="Flanagan, James M" uniqKey="Flanagan J" first="James M." last="Flanagan">James M. Flanagan</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ</wicri:regionArea><wicri:noRegion>SW7 2AZ</wicri:noRegion></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="A48">Sections of Epidemiology and Genetics at the Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, UK, SW7 3RP</nlm:aff><wicri:noCountry code="subfield">SW7 3RP</wicri:noCountry></affiliation></author><author><name sortKey="Gentry Maharaj, Aleksandra" sort="Gentry Maharaj, Aleksandra" uniqKey="Gentry Maharaj A" first="Aleksandra" last="Gentry-Maharaj">Aleksandra Gentry-Maharaj</name><affiliation wicri:level="1"><nlm:aff id="A49">Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU</wicri:regionArea><wicri:noRegion>NW1 2BU</wicri:noRegion></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation wicri:level="1"><nlm:aff id="A15">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053</wicri:regionArea><wicri:noRegion>Carlton VIC 3053</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea><wicri:noRegion>VIC 3010</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC 3806, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC 3806</wicri:regionArea><wicri:noRegion>VIC 3806</wicri:noRegion></affiliation></author><author><name sortKey="Glasspool, Rosalind M" sort="Glasspool, Rosalind M" uniqKey="Glasspool R" first="Rosalind M." last="Glasspool">Rosalind M. Glasspool</name><affiliation wicri:level="1"><nlm:aff id="A51">The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN</wicri:regionArea><wicri:noRegion>G12 0YN</wicri:noRegion></affiliation></author><author><name sortKey="Gonzalez Bosquet, Jesus" sort="Gonzalez Bosquet, Jesus" uniqKey="Gonzalez Bosquet J" first="Jesus" last="Gonzalez-Bosquet">Jesus Gonzalez-Bosquet</name><affiliation><nlm:aff id="A52">Department of Women's Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Goodman, Marc T" sort="Goodman, Marc T" uniqKey="Goodman M" first="Marc T." last="Goodman">Marc T. Goodman</name><affiliation><nlm:aff id="A53">Samuel Oschin Comprehensive Cancer Center Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA, 90048</nlm:aff><wicri:noCountry code="subfield">90048</wicri:noCountry></affiliation></author><author><name sortKey="Gore, Martin" sort="Gore, Martin" uniqKey="Gore M" first="Martin" last="Gore">Martin Gore</name><affiliation wicri:level="1"><nlm:aff id="A54">Gynecological Oncology Unit, The Royal Marsden Hospital, London, SW3 6JJ, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Gynecological Oncology Unit, The Royal Marsden Hospital, London, SW3 6JJ</wicri:regionArea><wicri:noRegion>SW3 6JJ</wicri:noRegion></affiliation></author><author><name sortKey="G Rski, Bohdan" sort="G Rski, Bohdan" uniqKey="G Rski B" first="Bohdan" last="G Rski">Bohdan G Rski</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A56">Department of Epidemiology and Biostatistics, Karolinska Istitutet, Stockholm, Sweden, 171-77</nlm:aff><wicri:noCountry code="subfield">171-77</wicri:noCountry></affiliation></author><author><name sortKey="Halle, Mari K" sort="Halle, Mari K" uniqKey="Halle M" first="Mari K." last="Halle">Mari K. Halle</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Harter, Philipp" sort="Harter, Philipp" uniqKey="Harter P" first="Philipp" last="Harter">Philipp Harter</name><affiliation wicri:level="1"><nlm:aff id="A40">Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden</wicri:regionArea><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen</wicri:regionArea><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Heitz, Florian" sort="Heitz, Florian" uniqKey="Heitz F" first="Florian" last="Heitz">Florian Heitz</name><affiliation wicri:level="1"><nlm:aff id="A40">Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden</wicri:regionArea><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>65199, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen</wicri:regionArea><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>45136, Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation wicri:level="3"><nlm:aff id="A59">Clinics of Obstetrics and Gynaecology, Hannover Medical School, 30625, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Clinics of Obstetrics and Gynaecology, Hannover Medical School, 30625, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Hoatlin, Maureen" sort="Hoatlin, Maureen" uniqKey="Hoatlin M" first="Maureen" last="Hoatlin">Maureen Hoatlin</name><affiliation><nlm:aff id="A60">Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, OR, USA, 97239</nlm:aff><wicri:noCountry code="subfield">97239</wicri:noCountry></affiliation></author><author><name sortKey="H Gdall, Claus K" sort="H Gdall, Claus K" uniqKey="H Gdall C" first="Claus K." last="H Gdall">Claus K. H Gdall</name><affiliation wicri:level="1"><nlm:aff id="A61">The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100</wicri:regionArea><wicri:noRegion>2100</wicri:noRegion></affiliation></author><author><name sortKey="H Gdall, Estrid" sort="H Gdall, Estrid" uniqKey="H Gdall E" first="Estrid" last="H Gdall">Estrid H Gdall</name><affiliation><nlm:aff id="A62">Department of Pathology, Molecular Unit, Herlev Hospital, University of Copenhagen, Denmark, 2730</nlm:aff><wicri:noCountry code="subfield">2730</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:aff id="A63">Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Hosono, Satoyo" sort="Hosono, Satoyo" uniqKey="Hosono S" first="Satoyo" last="Hosono">Satoyo Hosono</name><affiliation wicri:level="1"><nlm:aff id="A64">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681</wicri:regionArea><wicri:noRegion>464-8681</wicri:noRegion></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Jensen, Allan" sort="Jensen, Allan" uniqKey="Jensen A" first="Allan" last="Jensen">Allan Jensen</name><affiliation wicri:level="3"><nlm:aff id="A63">Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Jim, Heather" sort="Jim, Heather" uniqKey="Jim H" first="Heather" last="Jim">Heather Jim</name><affiliation><nlm:aff id="A65">Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Kalli, Kimberly R" sort="Kalli, Kimberly R" uniqKey="Kalli K" first="Kimberly R." last="Kalli">Kimberly R. Kalli</name><affiliation><nlm:aff id="A66">Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name><affiliation><nlm:aff id="A67">Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA, 90048</nlm:aff><wicri:noCountry code="subfield">90048</wicri:noCountry></affiliation></author><author><name sortKey="Kaye, Stanley B" sort="Kaye, Stanley B" uniqKey="Kaye S" first="Stanley B." last="Kaye">Stanley B. Kaye</name><affiliation wicri:level="1"><nlm:aff id="A68">Section of Medicine, Institute of Cancer Research, Sutton, SM2 5NG, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Medicine, Institute of Cancer Research, Sutton, SM2 5NG</wicri:regionArea><wicri:noRegion>SM2 5NG</wicri:noRegion></affiliation></author><author><name sortKey="Kelemen, Linda E" sort="Kelemen, Linda E" uniqKey="Kelemen L" first="Linda E." last="Kelemen">Linda E. Kelemen</name><affiliation wicri:level="4"><nlm:aff id="A69">Department of Popluation Health Research, Alberta Health Services-Cancer Care, Calgary, Alberta, Canada and Departments of Medical Genetics and Oncology, University of Calgary, Calgary, AB, Canada, T2N 2T9</nlm:aff><orgName type="university">Université de Calgary</orgName><country>Canada</country><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Kiemeney, Lambertus A" sort="Kiemeney, Lambertus A" uniqKey="Kiemeney L" first="Lambertus A." last="Kiemeney">Lambertus A. Kiemeney</name><affiliation wicri:level="1"><nlm:aff id="A7">Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A8">Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX</wicri:regionArea><wicri:noRegion>1066CX</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A70">Department of Urology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Urology, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation></author><author><name sortKey="Kikkawa, Fumitaka" sort="Kikkawa, Fumitaka" uniqKey="Kikkawa F" first="Fumitaka" last="Kikkawa">Fumitaka Kikkawa</name><affiliation wicri:level="1"><nlm:aff id="A71">Department of Obsterics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Obsterics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550</wicri:regionArea><wicri:noRegion>466-8550</wicri:noRegion></affiliation></author><author><name sortKey="Konecny, Gottfried E" sort="Konecny, Gottfried E" uniqKey="Konecny G" first="Gottfried E." last="Konecny">Gottfried E. Konecny</name><affiliation><nlm:aff id="A47">Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA, 90095</nlm:aff><wicri:noCountry code="subfield">90095</wicri:noCountry></affiliation></author><author><name sortKey="Krakstad, Camilla" sort="Krakstad, Camilla" uniqKey="Krakstad C" first="Camilla" last="Krakstad">Camilla Krakstad</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Kjaer, Susanne Kruger" sort="Kjaer, Susanne Kruger" uniqKey="Kjaer S" first="Susanne Krüger" last="Kjaer">Susanne Krüger Kjaer</name><affiliation wicri:level="1"><nlm:aff id="A61">The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100</wicri:regionArea><wicri:noRegion>2100</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A63">Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Kupryjanczyk, Jolanta" sort="Kupryjanczyk, Jolanta" uniqKey="Kupryjanczyk J" first="Jolanta" last="Kupryjanczyk">Jolanta Kupryjanczyk</name><affiliation><nlm:aff id="A37">Department of Molecular Pathology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><nlm:aff id="A72">Vesalius Research Center, VIB, 3000, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center, VIB, 3000, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A73">Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Lambrechts, Sandrina" sort="Lambrechts, Sandrina" uniqKey="Lambrechts S" first="Sandrina" last="Lambrechts">Sandrina Lambrechts</name><affiliation><nlm:aff id="A38">Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium, 3000</nlm:aff><wicri:noCountry code="subfield">3000</wicri:noCountry></affiliation></author><author><name sortKey="Lancaster, Johnathan M" sort="Lancaster, Johnathan M" uniqKey="Lancaster J" first="Johnathan M." last="Lancaster">Johnathan M. Lancaster</name><affiliation><nlm:aff id="A52">Department of Women's Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Le, Nhu D" sort="Le, Nhu D" uniqKey="Le N" first="Nhu D." last="Le">Nhu D. Le</name><affiliation><nlm:aff id="A74">Cancer Control Research, BC Cancer Agency, Vancouver, BC, Canada, G12 0YN</nlm:aff><wicri:noCountry code="subfield">G12 0YN</wicri:noCountry></affiliation></author><author><name sortKey="Leminen, Arto" sort="Leminen, Arto" uniqKey="Leminen A" first="Arto" last="Leminen">Arto Leminen</name><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Levine, Douglas A" sort="Levine, Douglas A" uniqKey="Levine D" first="Douglas A." last="Levine">Douglas A. Levine</name><affiliation><nlm:aff id="A75">Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10021</nlm:aff><wicri:noCountry code="subfield">10021</wicri:noCountry></affiliation></author><author><name sortKey="Liang, Dong" sort="Liang, Dong" uniqKey="Liang D" first="Dong" last="Liang">Dong Liang</name><affiliation><nlm:aff id="A76">College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA, 77044</nlm:aff><wicri:noCountry code="subfield">77044</wicri:noCountry></affiliation></author><author><name sortKey="Lim, Boon Kiong" sort="Lim, Boon Kiong" uniqKey="Lim B" first="Boon Kiong" last="Lim">Boon Kiong Lim</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Jie" sort="Lin, Jie" uniqKey="Lin J" first="Jie" last="Lin">Jie Lin</name><affiliation><nlm:aff id="A78">Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation wicri:level="1"><nlm:aff id="A79">Department of Cancer Epidemiology and Prevention, The Maria Sklodowska-Curie Memorial Cancer Center, 02-781, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Cancer Epidemiology and Prevention, The Maria Sklodowska-Curie Memorial Cancer Center, 02-781, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Karen H" sort="Lu, Karen H" uniqKey="Lu K" first="Karen H." last="Lu">Karen H. Lu</name><affiliation><nlm:aff id="A80">Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation></author><author><name sortKey="Lubi Ski, Jan" sort="Lubi Ski, Jan" uniqKey="Lubi Ski J" first="Jan" last="Lubi Ski">Jan Lubi Ski</name><affiliation><nlm:aff id="A55">International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</nlm:aff><wicri:noCountry code="subfield">70-115</wicri:noCountry></affiliation></author><author><name sortKey="Lurie, Galina" sort="Lurie, Galina" uniqKey="Lurie G" first="Galina" last="Lurie">Galina Lurie</name><affiliation><nlm:aff id="A81">Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA, 96813</nlm:aff><wicri:noCountry code="subfield">96813</wicri:noCountry></affiliation></author><author><name sortKey="Massuger, Leon F A G" sort="Massuger, Leon F A G" uniqKey="Massuger L" first="Leon F. A. G." last="Massuger">Leon F. A. G. Massuger</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation></author><author><name sortKey="Matsuo, Keitaro" sort="Matsuo, Keitaro" uniqKey="Matsuo K" first="Keitaro" last="Matsuo">Keitaro Matsuo</name><affiliation wicri:level="1"><nlm:aff id="A64">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681</wicri:regionArea><wicri:noRegion>464-8681</wicri:noRegion></affiliation></author><author><name sortKey="Mcguire, Valerie" sort="Mcguire, Valerie" uniqKey="Mcguire V" first="Valerie" last="Mcguire">Valerie Mcguire</name><affiliation><nlm:aff id="A83">Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford CA, USA, 94305</nlm:aff><wicri:noCountry code="subfield">94305</wicri:noCountry></affiliation></author><author><name sortKey="Mclaughlin, John R" sort="Mclaughlin, John R" uniqKey="Mclaughlin J" first="John R" last="Mclaughlin">John R. Mclaughlin</name><affiliation wicri:level="4"><nlm:aff id="A84">Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, ON, M5T 3M7, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, ON, M5T 3M7</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation><nlm:aff id="A85">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, M5G 1X5</nlm:aff><wicri:noCountry code="subfield">M5G 1X5</wicri:noCountry></affiliation></author><author><name sortKey="Menon, Usha" sort="Menon, Usha" uniqKey="Menon U" first="Usha" last="Menon">Usha Menon</name><affiliation wicri:level="1"><nlm:aff id="A49">Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU</wicri:regionArea><wicri:noRegion>NW1 2BU</wicri:noRegion></affiliation></author><author><name sortKey="Modugno, Francesmary" sort="Modugno, Francesmary" uniqKey="Modugno F" first="Francesmary" last="Modugno">Francesmary Modugno</name><affiliation><nlm:aff id="A78">Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation><affiliation><nlm:aff id="A80">Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation><affiliation><nlm:aff id="A86">Women's Cancer Research Program, Magee-Womens Research Institute and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA, 15213</nlm:aff><wicri:noCountry code="subfield">15213</wicri:noCountry></affiliation></author><author><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B." last="Moysich">Kirsten B. Moysich</name><affiliation><nlm:aff id="A87">Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA, 14263</nlm:aff><wicri:noCountry code="subfield">14263</wicri:noCountry></affiliation></author><author><name sortKey="Nakanishi, Toru" sort="Nakanishi, Toru" uniqKey="Nakanishi T" first="Toru" last="Nakanishi">Toru Nakanishi</name><affiliation wicri:level="1"><nlm:aff id="A88">Department of Gynecologic Oncology, Aichi Cancer Center Central Hospital, Nagoya, Aichi, Nagoya, 464-8681, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Gynecologic Oncology, Aichi Cancer Center Central Hospital, Nagoya, Aichi, Nagoya, 464-8681</wicri:regionArea><wicri:noRegion>464-8681</wicri:noRegion></affiliation></author><author><name sortKey="Narod, Steven A" sort="Narod, Steven A" uniqKey="Narod S" first="Steven A." last="Narod">Steven A. Narod</name><affiliation wicri:level="4"><nlm:aff id="A89">Women's College Research Institute, University of Toronto, Toronto, Ontario, Canada, M5G 1N8</nlm:aff><orgName type="university">Université de Toronto</orgName><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Nedergaard, Lotte" sort="Nedergaard, Lotte" uniqKey="Nedergaard L" first="Lotte" last="Nedergaard">Lotte Nedergaard</name><affiliation wicri:level="1"><nlm:aff id="A90">Department of Pathology, Rigshospitalet, University of Copenhagen, 2100, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Pathology, Rigshospitalet, University of Copenhagen, 2100</wicri:regionArea><wicri:noRegion>2100</wicri:noRegion></affiliation></author><author><name sortKey="Ness, Roberta B" sort="Ness, Roberta B" uniqKey="Ness R" first="Roberta B." last="Ness">Roberta B. Ness</name><affiliation><nlm:aff id="A91">The University of Texas School of Public Health, Houston, TX, USA, 77030</nlm:aff><wicri:noCountry code="subfield">77030</wicri:noCountry></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation wicri:level="3"><nlm:aff id="A29">German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Noushmehr, Houtan" sort="Noushmehr, Houtan" uniqKey="Noushmehr H" first="Houtan" last="Noushmehr">Houtan Noushmehr</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Urology, Microbiology and Preventive Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90089</nlm:aff><orgName type="university">Université de Californie du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A92">USC Epigenome Center, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, 90089</nlm:aff><orgName type="university">Université de Californie du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Odunsi, Kunle" sort="Odunsi, Kunle" uniqKey="Odunsi K" first="Kunle" last="Odunsi">Kunle Odunsi</name><affiliation><nlm:aff id="A93">Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA, 14263</nlm:aff><wicri:noCountry code="subfield">14263</wicri:noCountry></affiliation></author><author><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H." last="Olson">Sara H. Olson</name><affiliation><nlm:aff id="A94">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10065</nlm:aff><wicri:noCountry code="subfield">10065</wicri:noCountry></affiliation></author><author><name sortKey="Orlow, Irene" sort="Orlow, Irene" uniqKey="Orlow I" first="Irene" last="Orlow">Irene Orlow</name><affiliation><nlm:aff id="A94">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10065</nlm:aff><wicri:noCountry code="subfield">10065</wicri:noCountry></affiliation></author><author><name sortKey="Paul, James" sort="Paul, James" uniqKey="Paul J" first="James" last="Paul">James Paul</name><affiliation wicri:level="1"><nlm:aff id="A51">The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN</wicri:regionArea><wicri:noRegion>G12 0YN</wicri:noRegion></affiliation></author><author><name sortKey="Pearce, Celeste L" sort="Pearce, Celeste L" uniqKey="Pearce C" first="Celeste L" last="Pearce">Celeste L. Pearce</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Pejovic, Tanja" sort="Pejovic, Tanja" uniqKey="Pejovic T" first="Tanja" last="Pejovic">Tanja Pejovic</name><affiliation><nlm:aff id="A95">Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA, 97239</nlm:aff><wicri:noCountry code="subfield">97239</wicri:noCountry></affiliation><affiliation><nlm:aff id="A96">Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA, 97239</nlm:aff><wicri:noCountry code="subfield">97239</wicri:noCountry></affiliation></author><author><name sortKey="Pelttari, Liisa M" sort="Pelttari, Liisa M" uniqKey="Pelttari L" first="Liisa M." last="Pelttari">Liisa M. Pelttari</name><affiliation><nlm:aff id="A26">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</nlm:aff><wicri:noCountry code="subfield">00530</wicri:noCountry></affiliation></author><author><name sortKey="Pike, Malcolm C" sort="Pike, Malcolm C" uniqKey="Pike M" first="Malcolm C." last="Pike">Malcolm C. Pike</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation><affiliation><nlm:aff id="A94">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10065</nlm:aff><wicri:noCountry code="subfield">10065</wicri:noCountry></affiliation></author><author><name sortKey="Poole, Elizabeth M" sort="Poole, Elizabeth M" uniqKey="Poole E" first="Elizabeth M." last="Poole">Elizabeth M. Poole</name><affiliation><nlm:aff id="A97">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation><affiliation><nlm:aff id="A98">Channing Laboratory, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Raska, Paola" sort="Raska, Paola" uniqKey="Raska P" first="Paola" last="Raska">Paola Raska</name><affiliation><nlm:aff id="A18">Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA, 44195</nlm:aff><wicri:noCountry code="subfield">44195</wicri:noCountry></affiliation></author><author><name sortKey="Renner, Stefan P" sort="Renner, Stefan P" uniqKey="Renner S" first="Stefan P." last="Renner">Stefan P. Renner</name><affiliation wicri:level="1"><nlm:aff id="A19">University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054</wicri:regionArea><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion><wicri:noRegion>91054</wicri:noRegion></affiliation></author><author><name sortKey="Risch, Harvey A" sort="Risch, Harvey A" uniqKey="Risch H" first="Harvey A." last="Risch">Harvey A. Risch</name><affiliation><nlm:aff id="A99">Department of Epidemiology and Public Health, Yale University School of Public Health and School of Medicine, New Haven, CT, USA, 06520</nlm:aff><wicri:noCountry code="subfield">06520</wicri:noCountry></affiliation></author><author><name sortKey="Rodriguez Rodriguez, Lorna" sort="Rodriguez Rodriguez, Lorna" uniqKey="Rodriguez Rodriguez L" first="Lorna" last="Rodriguez-Rodriguez">Lorna Rodriguez-Rodriguez</name><affiliation><nlm:aff id="A17">The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA, 08901</nlm:aff><wicri:noCountry code="subfield">08901</wicri:noCountry></affiliation></author><author><name sortKey="Rossing, Mary Anne" sort="Rossing, Mary Anne" uniqKey="Rossing M" first="Mary Anne" last="Rossing">Mary Anne Rossing</name><affiliation><nlm:aff id="A100">Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, 98109</nlm:aff><wicri:noCountry code="subfield">98109</wicri:noCountry></affiliation><affiliation wicri:level="4"><nlm:aff id="A101">Department of Epidemiology, University of Washington, Seattle, WA, USA, 98109</nlm:aff><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation wicri:level="3"><nlm:aff id="A29">German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Runnebaum, Ingo B" sort="Runnebaum, Ingo B" uniqKey="Runnebaum I" first="Ingo B." last="Runnebaum">Ingo B. Runnebaum</name><affiliation wicri:level="1"><nlm:aff id="A42">Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena</wicri:regionArea><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>07743, Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Rzepecka, Iwona K" sort="Rzepecka, Iwona K" uniqKey="Rzepecka I" first="Iwona K." last="Rzepecka">Iwona K. Rzepecka</name><affiliation><nlm:aff id="A37">Department of Molecular Pathology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Salvesen, Helga B" sort="Salvesen, Helga B" uniqKey="Salvesen H" first="Helga B." last="Salvesen">Helga B. Salvesen</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Schwaab, Ira" sort="Schwaab, Ira" uniqKey="Schwaab I" first="Ira" last="Schwaab">Ira Schwaab</name><affiliation wicri:level="1"><nlm:aff id="A102">Institut für Humangenetik Wiesbaden, 65187, Wiesbaden, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Humangenetik Wiesbaden, 65187, Wiesbaden</wicri:regionArea><wicri:noRegion>65187, Wiesbaden</wicri:noRegion><wicri:noRegion>65187, Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="1"><nlm:aff id="A15">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053</wicri:regionArea><wicri:noRegion>Carlton VIC 3053</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea><wicri:noRegion>VIC 3010</wicri:noRegion></affiliation></author><author><name sortKey="Shridhar, Vijayalakshmi" sort="Shridhar, Vijayalakshmi" uniqKey="Shridhar V" first="Vijayalakshmi" last="Shridhar">Vijayalakshmi Shridhar</name><affiliation><nlm:aff id="A103">Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="A27">Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA, 37232</nlm:aff><wicri:noCountry code="subfield">37232</wicri:noCountry></affiliation></author><author><name sortKey="Shvetsov, Yurii B" sort="Shvetsov, Yurii B" uniqKey="Shvetsov Y" first="Yurii B." last="Shvetsov">Yurii B. Shvetsov</name><affiliation><nlm:aff id="A81">Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA, 96813</nlm:aff><wicri:noCountry code="subfield">96813</wicri:noCountry></affiliation></author><author><name sortKey="Sieh, Weiva" sort="Sieh, Weiva" uniqKey="Sieh W" first="Weiva" last="Sieh">Weiva Sieh</name><affiliation><nlm:aff id="A83">Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford CA, USA, 94305</nlm:aff><wicri:noCountry code="subfield">94305</wicri:noCountry></affiliation></author><author><name sortKey="Song, Honglin" sort="Song, Honglin" uniqKey="Song H" first="Honglin" last="Song">Honglin Song</name><affiliation wicri:level="4"><nlm:aff id="A3">Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation wicri:level="1"><nlm:aff id="A104">Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, VIC 3053, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, VIC 3053</wicri:regionArea><wicri:noRegion>VIC 3053</wicri:noRegion></affiliation></author><author><name sortKey="Spiewankiewicz, Beata" sort="Spiewankiewicz, Beata" uniqKey="Spiewankiewicz B" first="Beata" last="Spiewankiewicz">Beata Spiewankiewicz</name><affiliation><nlm:aff id="A105">Department of Gynecologic Oncology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</nlm:aff><wicri:noCountry code="subfield">02-781</wicri:noCountry></affiliation></author><author><name sortKey="Stram, Daniel" sort="Stram, Daniel" uniqKey="Stram D" first="Daniel" last="Stram">Daniel Stram</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Sutphen, Rebecca" sort="Sutphen, Rebecca" uniqKey="Sutphen R" first="Rebecca" last="Sutphen">Rebecca Sutphen</name><affiliation wicri:level="4"><nlm:aff id="A106">Pediatrics Epidemiology Center, College of Medicine, University of South Florida, Tampa, FL, USA, 33612</nlm:aff><orgName type="university">Université de Floride du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Tampa</settlement><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Terry, Kathryn L" sort="Terry, Kathryn L" uniqKey="Terry K" first="Kathryn L." last="Terry">Kathryn L. Terry</name><affiliation><nlm:aff id="A36">Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Tessier, Daniel C" sort="Tessier, Daniel C" uniqKey="Tessier D" first="Daniel C." last="Tessier">Daniel C. Tessier</name><affiliation><nlm:aff id="A14">McGill University and Génome Québec Innovation Centre, Montréal (Québec) Canada, H3A 0G1</nlm:aff><wicri:noCountry code="subfield">H3A 0G1</wicri:noCountry></affiliation></author><author><name sortKey="Thompson, Pamela J" sort="Thompson, Pamela J" uniqKey="Thompson P" first="Pamela J." last="Thompson">Pamela J. Thompson</name><affiliation><nlm:aff id="A53">Samuel Oschin Comprehensive Cancer Center Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA, 90048</nlm:aff><wicri:noCountry code="subfield">90048</wicri:noCountry></affiliation></author><author><name sortKey="Tworoger, Shelley S" sort="Tworoger, Shelley S" uniqKey="Tworoger S" first="Shelley S." last="Tworoger">Shelley S. Tworoger</name><affiliation><nlm:aff id="A97">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation><affiliation><nlm:aff id="A98">Channing Laboratory, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Van Altena, Anne M" sort="Van Altena, Anne M" uniqKey="Van Altena A" first="Anne M." last="Van Altena">Anne M. Van Altena</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500</wicri:regionArea><wicri:noRegion>HB 6500</wicri:noRegion></affiliation></author><author><name sortKey="Vergote, Ignace" sort="Vergote, Ignace" uniqKey="Vergote I" first="Ignace" last="Vergote">Ignace Vergote</name><affiliation><nlm:aff id="A38">Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium, 3000</nlm:aff><wicri:noCountry code="subfield">3000</wicri:noCountry></affiliation></author><author><name sortKey="Vierkant, Robert A" sort="Vierkant, Robert A" uniqKey="Vierkant R" first="Robert A." last="Vierkant">Robert A. Vierkant</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Vincent, Daniel" sort="Vincent, Daniel" uniqKey="Vincent D" first="Daniel" last="Vincent">Daniel Vincent</name><affiliation><nlm:aff id="A14">McGill University and Génome Québec Innovation Centre, Montréal (Québec) Canada, H3A 0G1</nlm:aff><wicri:noCountry code="subfield">H3A 0G1</wicri:noCountry></affiliation></author><author><name sortKey="Vitonis, Allison F" sort="Vitonis, Allison F" uniqKey="Vitonis A" first="Allison F." last="Vitonis">Allison F. Vitonis</name><affiliation><nlm:aff id="A36">Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, 02115</nlm:aff><wicri:noCountry code="subfield">02115</wicri:noCountry></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation wicri:level="4"><nlm:aff id="A107">Department of Obstetrics and Gynecology, University of Ulm, Ulm, 89081, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Ulm, Ulm, 89081</wicri:regionArea><wicri:noRegion>89081</wicri:noRegion><orgName type="university">Université d'Ulm</orgName><placeName><settlement type="city">Ulm</settlement><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region></placeName></affiliation></author><author><name sortKey="Weber, Rachel Palmieri" sort="Weber, Rachel Palmieri" uniqKey="Weber R" first="Rachel Palmieri" last="Weber">Rachel Palmieri Weber</name><affiliation><nlm:aff id="A108">Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation></author><author><name sortKey="Wentzensen, Nicolas" sort="Wentzensen, Nicolas" uniqKey="Wentzensen N" first="Nicolas" last="Wentzensen">Nicolas Wentzensen</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Whittemore, Alice S" sort="Whittemore, Alice S" uniqKey="Whittemore A" first="Alice S." last="Whittemore">Alice S. Whittemore</name><affiliation><nlm:aff id="A83">Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford CA, USA, 94305</nlm:aff><wicri:noCountry code="subfield">94305</wicri:noCountry></affiliation></author><author><name sortKey="Wik, Elisabeth" sort="Wik, Elisabeth" uniqKey="Wik E" first="Elisabeth" last="Wik">Elisabeth Wik</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006</wicri:regionArea><wicri:noRegion>HB 5006</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, University of Bergen, 5006, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Wilkens, Lynne R" sort="Wilkens, Lynne R" uniqKey="Wilkens L" first="Lynne R." last="Wilkens">Lynne R. Wilkens</name><affiliation><nlm:aff id="A81">Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA, 96813</nlm:aff><wicri:noCountry code="subfield">96813</wicri:noCountry></affiliation></author><author><name sortKey="Winterhoff, Boris" sort="Winterhoff, Boris" uniqKey="Winterhoff B" first="Boris" last="Winterhoff">Boris Winterhoff</name><affiliation><nlm:aff id="A109">Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Woo, Yin Ling" sort="Woo, Yin Ling" uniqKey="Woo Y" first="Yin Ling" last="Woo">Yin Ling Woo</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Anna H" sort="Wu, Anna H" uniqKey="Wu A" first="Anna H." last="Wu">Anna H. Wu</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation><nlm:aff id="A110">Shanghai Cancer Institute, Shanghai, China, 2200-25</nlm:aff><wicri:noCountry code="subfield">2200-25</wicri:noCountry></affiliation></author><author><name sortKey="Yang, Hannah P" sort="Yang, Hannah P" uniqKey="Yang H" first="Hannah P." last="Yang">Hannah P. Yang</name><affiliation><nlm:aff id="A22">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</nlm:aff><wicri:noCountry code="subfield">20892</wicri:noCountry></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A27">Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA, 37232</nlm:aff><wicri:noCountry code="subfield">37232</wicri:noCountry></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation><nlm:aff id="A111">Department of Epidemiology, Center for Cancer Genetics Research and Prevention, School of Medicine, University of California Irvine, Irvine, California, USA, 92697</nlm:aff><wicri:noCountry code="subfield">92697</wicri:noCountry></affiliation></author><author><name sortKey="Zulkifli, Famida" sort="Zulkifli, Famida" uniqKey="Zulkifli F" first="Famida" last="Zulkifli">Famida Zulkifli</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</nlm:aff><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur</wicri:regionArea><wicri:noRegion>Federal Territory of Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Phelan, Catherine M" sort="Phelan, Catherine M" uniqKey="Phelan C" first="Catherine M." last="Phelan">Catherine M. Phelan</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Iversen, Edwin" sort="Iversen, Edwin" uniqKey="Iversen E" first="Edwin" last="Iversen">Edwin Iversen</name><affiliation><nlm:aff id="A112">Department of Statistical Science, Duke University, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation></author><author><name sortKey="Schildkraut, Joellen M" sort="Schildkraut, Joellen M" uniqKey="Schildkraut J" first="Joellen M." last="Schildkraut">Joellen M. Schildkraut</name><affiliation><nlm:aff id="A108">Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation><affiliation><nlm:aff id="A113">Cancer Prevention, Detection and Control Research Program, Duke Cancer Institute, Durham, North Carolina, USA, 27708-0251</nlm:aff><wicri:noCountry code="subfield">27708-0251</wicri:noCountry></affiliation></author><author><name sortKey="Berchuck, Andrew" sort="Berchuck, Andrew" uniqKey="Berchuck A" first="Andrew" last="Berchuck">Andrew Berchuck</name><affiliation><nlm:aff id="A114">Department of Obstetrics and Gynecology, Duke Comprehensive Cancer Center, Durham, NC, USA, 27708</nlm:aff><wicri:noCountry code="subfield">27708</wicri:noCountry></affiliation></author><author><name sortKey="Fridley, Brooke L" sort="Fridley, Brooke L" uniqKey="Fridley B" first="Brooke L." last="Fridley">Brooke L. Fridley</name><affiliation><nlm:aff id="A115">Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA, 66160</nlm:aff><wicri:noCountry code="subfield">66160</wicri:noCountry></affiliation></author><author><name sortKey="Goode, Ellen L" sort="Goode, Ellen L" uniqKey="Goode E" first="Ellen L." last="Goode">Ellen L. Goode</name><affiliation><nlm:aff id="A31">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</nlm:aff><wicri:noCountry code="subfield">55905</wicri:noCountry></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="4"><nlm:aff id="A11">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Monteiro, Alvaro N A" sort="Monteiro, Alvaro N A" uniqKey="Monteiro A" first="Alvaro N. A." last="Monteiro">Alvaro N. A. Monteiro</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Sellers, Thomas A" sort="Sellers, Thomas A" uniqKey="Sellers T" first="Thomas A." last="Sellers">Thomas A. Sellers</name><affiliation><nlm:aff id="A1">Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</nlm:aff><wicri:noCountry code="subfield">33612</wicri:noCountry></affiliation></author><author><name sortKey="Gayther, Simon A" sort="Gayther, Simon A" uniqKey="Gayther S" first="Simon A." last="Gayther">Simon A. Gayther</name><affiliation><nlm:aff id="A2">Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</nlm:aff><wicri:noCountry code="subfield">90033</wicri:noCountry></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3′ untranslated region at putative microRNA (miRNA) binding sites represent functional targets that influence EOC susceptibility. Here, we evaluate the association between 767 miRNA binding site single nucleotide polymorphisms (miRSNPs) and EOC risk in 18,174 EOC cases and 26,134 controls from 43 studies genotyped through the Collaborative Oncological Gene-environment Study. We identify several miRSNPs associated with invasive serous EOC risk (OR=1.12, <italic>P</italic>=10<sup>−8</sup>) mapping to an inversion polymorphism at 17q21.31. Additional genotyping of non-miRSNPs at 17q21.31 reveals stronger signals outside the inversion (<italic>P</italic>=10<sup>−10</sup>). Variation at 17q21.31 associates with neurological diseases, and our collaboration is the first to report an association with EOC susceptibility. An integrated molecular analysis in this region provides evidence for <italic>ARHGAP27</italic> and <italic>PLEKHM1</italic> as candidate EOC susceptibility genes.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Freedman, Ml" uniqKey="Freedman M">ML Freedman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dahiya, N" uniqKey="Dahiya N">N Dahiya</name></author><author><name sortKey="Morin, Pj" uniqKey="Morin P">PJ Morin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lytle, Jr" uniqKey="Lytle J">JR Lytle</name></author><author><name sortKey="Yario, Ta" uniqKey="Yario T">TA Yario</name></author><author><name sortKey="Steitz, Ja" uniqKey="Steitz J">JA Steitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, I" uniqKey="Lee I">I Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Permuth 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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101528555</journal-id><journal-id journal-id-type="pubmed-jr-id">37539</journal-id><journal-id journal-id-type="nlm-ta">Nat Commun</journal-id><journal-id journal-id-type="iso-abbrev">Nat Commun</journal-id><journal-title-group><journal-title>Nature communications</journal-title></journal-title-group><issn pub-type="epub">2041-1723</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23535648</article-id><article-id pub-id-type="pmc">3709460</article-id><article-id pub-id-type="doi">10.1038/ncomms2613</article-id><article-id pub-id-type="manuscript">NIHMS447293</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Permuth-Wey</surname><given-names>Jennifer</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Lawrenson</surname><given-names>Kate</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Shen</surname><given-names>Howard C.</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Velkova</surname><given-names>Aneliya</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Tyrer</surname><given-names>Jonathan P.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Zhihua</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Lin</surname><given-names>Hui-Yi</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Y. Ann</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Tsai</surname><given-names>Ya-Yu</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Qu</surname><given-names>Xiaotao</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Ramus</surname><given-names>Susan J.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Karevan</surname><given-names>Rod</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Lee</surname><given-names>Janet</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Lee</surname><given-names>Nathan</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Larson</surname><given-names>Melissa C.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Aben</surname><given-names>Katja K.</given-names></name><xref ref-type="aff" rid="A7">7</xref><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author"><name><surname>Anton-Culver</surname><given-names>Hoda</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Antonenkova</surname><given-names>Natalia</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Antoniou</surname><given-names>Antonis</given-names></name><xref ref-type="aff" rid="A11">11</xref></contrib><contrib contrib-type="author"><name><surname>Armasu</surname><given-names>Sebastian M.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><collab>Australian Cancer Study</collab><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><collab>Australian Ovarian Cancer Study</collab><xref ref-type="aff" rid="A12">12</xref><xref ref-type="aff" rid="A13">13</xref></contrib><contrib contrib-type="author"><name><surname>Bacot</surname><given-names>François</given-names></name><xref ref-type="aff" rid="A14">14</xref></contrib><contrib contrib-type="author"><name><surname>Baglietto</surname><given-names>Laura</given-names></name><xref ref-type="aff" rid="A15">15</xref><xref ref-type="aff" rid="A16">16</xref></contrib><contrib contrib-type="author"><name><surname>Bandera</surname><given-names>Elisa V.</given-names></name><xref ref-type="aff" rid="A17">17</xref></contrib><contrib contrib-type="author"><name><surname>Barnholtz-Sloan</surname><given-names>Jill</given-names></name><xref ref-type="aff" rid="A18">18</xref></contrib><contrib contrib-type="author"><name><surname>Beckmann</surname><given-names>Matthias W.</given-names></name><xref ref-type="aff" rid="A19">19</xref></contrib><contrib contrib-type="author"><name><surname>Birrer</surname><given-names>Michael J.</given-names></name><xref ref-type="aff" rid="A20">20</xref></contrib><contrib contrib-type="author"><name><surname>Bloom</surname><given-names>Greg</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Bogdanova</surname><given-names>Natalia</given-names></name><xref ref-type="aff" rid="A21">21</xref></contrib><contrib contrib-type="author"><name><surname>Brinton</surname><given-names>Louise A.</given-names></name><xref ref-type="aff" rid="A22">22</xref></contrib><contrib contrib-type="author"><name><surname>Brooks-Wilson</surname><given-names>Angela</given-names></name><xref ref-type="aff" rid="A23">23</xref></contrib><contrib contrib-type="author"><name><surname>Brown</surname><given-names>Robert</given-names></name><xref ref-type="aff" rid="A24">24</xref></contrib><contrib contrib-type="author"><name><surname>Butzow</surname><given-names>Ralf</given-names></name><xref ref-type="aff" rid="A25">25</xref><xref ref-type="aff" rid="A26">26</xref></contrib><contrib contrib-type="author"><name><surname>Cai</surname><given-names>Qiuyin</given-names></name><xref ref-type="aff" rid="A27">27</xref></contrib><contrib contrib-type="author"><name><surname>Campbell</surname><given-names>Ian</given-names></name><xref ref-type="aff" rid="A13">13</xref><xref ref-type="aff" rid="A28">28</xref></contrib><contrib contrib-type="author"><name><surname>Chang-Claude</surname><given-names>Jenny</given-names></name><xref ref-type="aff" rid="A29">29</xref></contrib><contrib contrib-type="author"><name><surname>Chanock</surname><given-names>Stephen</given-names></name><xref ref-type="aff" rid="A22">22</xref></contrib><contrib contrib-type="author"><name><surname>Chenevix-Trench</surname><given-names>Georgia</given-names></name><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><name><surname>Cheng</surname><given-names>Jin Q.</given-names></name><xref ref-type="aff" rid="A30">30</xref></contrib><contrib contrib-type="author"><name><surname>Cicek</surname><given-names>Mine S.</given-names></name><xref ref-type="aff" rid="A31">31</xref></contrib><contrib contrib-type="author"><name><surname>Coetzee</surname><given-names>Gerhard A.</given-names></name><xref ref-type="aff" rid="A32">32</xref></contrib><contrib contrib-type="author"><collab>Consortium of Investigators of Modifiers of BRCA1/2</collab><xref ref-type="aff" rid="A33">33</xref><xref ref-type="aff" rid="A34">34</xref></contrib><contrib contrib-type="author"><name><surname>Cook</surname><given-names>Linda S.</given-names></name><xref ref-type="aff" rid="A35">35</xref></contrib><contrib contrib-type="author"><name><surname>Couch</surname><given-names>Fergus J.</given-names></name><xref ref-type="aff" rid="A34">34</xref></contrib><contrib contrib-type="author"><name><surname>Cramer</surname><given-names>Daniel W.</given-names></name><xref ref-type="aff" rid="A36">36</xref></contrib><contrib contrib-type="author"><name><surname>Cunningham</surname><given-names>Julie M.</given-names></name><xref ref-type="aff" rid="A31">31</xref></contrib><contrib contrib-type="author"><name><surname>Dansonka-Mieszkowska</surname><given-names>Agnieszka</given-names></name><xref ref-type="aff" rid="A37">37</xref></contrib><contrib contrib-type="author"><name><surname>Despierre</surname><given-names>Evelyn</given-names></name><xref ref-type="aff" rid="A38">38</xref></contrib><contrib contrib-type="author"><name><surname>Doherty</surname><given-names>Jennifer A</given-names></name><xref ref-type="aff" rid="A39">39</xref></contrib><contrib 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contrib-type="author"><name><surname>Zulkifli</surname><given-names>Famida</given-names></name><xref ref-type="aff" rid="A77">77</xref></contrib><contrib contrib-type="author"><name><surname>Phelan</surname><given-names>Catherine M.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Iversen</surname><given-names>Edwin</given-names></name><xref ref-type="aff" rid="A112">112</xref></contrib><contrib contrib-type="author"><name><surname>Schildkraut</surname><given-names>Joellen M.</given-names></name><xref ref-type="aff" rid="A108">108</xref><xref ref-type="aff" rid="A113">113</xref></contrib><contrib contrib-type="author"><name><surname>Berchuck</surname><given-names>Andrew</given-names></name><xref ref-type="aff" rid="A114">114</xref></contrib><contrib contrib-type="author"><name><surname>Fridley</surname><given-names>Brooke L.</given-names></name><xref ref-type="aff" rid="A115">115</xref></contrib><contrib contrib-type="author"><name><surname>Goode</surname><given-names>Ellen L.</given-names></name><xref ref-type="aff" rid="A31">31</xref></contrib><contrib contrib-type="author"><name><surname>Pharoah</surname><given-names>Paul D. P.</given-names></name><xref ref-type="aff" rid="A11">11</xref><xref ref-type="aff" rid="A43">43</xref></contrib><contrib contrib-type="author"><name><surname>Monteiro</surname><given-names>Alvaro N.A.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Sellers</surname><given-names>Thomas A.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Gayther</surname><given-names>Simon A.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA, 33612</aff><aff id="A2"><label>2</label>Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90033</aff><aff id="A3"><label>3</label>Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</aff><aff id="A4"><label>4</label>Department of Biomedical Informatics, Moffitt Cancer Center, Tampa, FL, USA, 33612</aff><aff id="A5"><label>5</label>Department of Biostatistics, Moffitt Cancer Center, Tampa, FL, USA, 33612</aff><aff id="A6"><label>6</label>Department of Health Science Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA, 55905</aff><aff id="A7"><label>7</label>Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</aff><aff id="A8"><label>8</label>Comprehensive Cancer Center, the Netherlands, Utrecht, Amsterdam, 1066CX, The Netherlands</aff><aff id="A9"><label>9</label>Department of Epidemiology, Director of Genetic Epidemiology Research Institute, UCI Center of Medicine, University of California Irvine, Irvine, CA, USA, 92697</aff><aff id="A10"><label>10</label>Byelorussian Institute for Oncology and Medical Radiology Aleksandrov N.N., 223040, Minsk, Belarus</aff><aff id="A11"><label>11</label>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK</aff><aff id="A12"><label>12</label>Queensland Institute of Medical Research, Brisbane QLD 4006, Australia</aff><aff id="A13"><label>13</label>Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3002, Australia</aff><aff id="A14"><label>14</label>McGill University and Génome Québec Innovation Centre, Montréal (Québec) Canada, H3A 0G1</aff><aff id="A15"><label>15</label>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton VIC 3053, Australia</aff><aff id="A16"><label>16</label>Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, University of Melbourne, Melbourne, VIC 3010, Australia</aff><aff id="A17"><label>17</label>The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA, 08901</aff><aff id="A18"><label>18</label>Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA, 44195</aff><aff id="A19"><label>19</label>University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen, 91054, Germany</aff><aff id="A20"><label>20</label>Massachusetts General Hospital, Boston, MA, USA, 02114</aff><aff id="A21"><label>21</label>Gynaecology Research Unit, Hannover Medical School, Hannover, 30625, Germany</aff><aff id="A22"><label>22</label>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD, USA, 20892</aff><aff id="A23"><label>23</label>Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada, V5Z 1L3</aff><aff id="A24"><label>24</label>Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK</aff><aff id="A25"><label>25</label>Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland, 00530</aff><aff id="A26"><label>26</label>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland, 00530</aff><aff id="A27"><label>27</label>Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA, 37232</aff><aff id="A28"><label>28</label>Department of Pathology, University of Melbourne, Parkville, VIC 3053, Australia</aff><aff id="A29"><label>29</label>German Cancer Research Center, Division of Cancer Epidemiology, 69120, Heidelberg, Germany</aff><aff id="A30"><label>30</label>Department of Interdisciplinary Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</aff><aff id="A31"><label>31</label>Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA, 55905</aff><aff id="A32"><label>32</label>Department of Urology, Microbiology and Preventive Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, USA, 90089</aff><aff id="A33"><label>33</label>Cancer Research UK, Genetic Epidemiology Unit, Dept of Public Health & Primary Care, University of Cambridge, Strangeways Research Lab, Cambridge, CB1 8RN, UK</aff><aff id="A34"><label>34</label>Department of Laboratory of Medicine and Pathology, Mayo Clinic, Rochester, MN, USA, 55905</aff><aff id="A35"><label>35</label>Division Epidemiology and Biostatistics, University of New Mexico, Albuquerque, NM, USA, 87131</aff><aff id="A36"><label>36</label>Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, 02115</aff><aff id="A37"><label>37</label>Department of Molecular Pathology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</aff><aff id="A38"><label>38</label>Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium, 3000</aff><aff id="A39"><label>39</label>Section of Biostatistics and Epidemiology, The Geisel School of Medicine at Dartmouth, Lebanon, NH, USA, 03755</aff><aff id="A40"><label>40</label>Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Klinik Wiesbaden, 65199, Wiesbaden, Germany</aff><aff id="A41"><label>41</label>Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136, Essen, Germany</aff><aff id="A42"><label>42</label>Department of Gynecology and Obstetrics, Jena University Hospital, 07743, Jena, Germany</aff><aff id="A43"><label>43</label>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</aff><aff id="A44"><label>44</label>Faculty of Medicine, University of Southampton, University Hospital Southampton, SO17 1BJ, UK</aff><aff id="A45"><label>45</label>Maggee Women's Hospital, Pittsburg, PA, USA, 15213</aff><aff id="A46"><label>46</label>Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, 91054, Erlangen, Germany</aff><aff id="A47"><label>47</label>Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA, 90095</aff><aff id="A48"><label>48</label>Sections of Epidemiology and Genetics at the Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, UK, SW7 3RP</aff><aff id="A49"><label>49</label>Gynaecological Cancer Research Centre, UCL EGA Institute for Women's Health, London, NW1 2BU, United Kingdom</aff><aff id="A50"><label>50</label>Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC 3806, Australia</aff><aff id="A51"><label>51</label>The Beatson West of Scotland Cancer Centre, Glasgow, G12 0YN, UK</aff><aff id="A52"><label>52</label>Department of Women's Oncology, Moffitt Cancer Center, Tampa, FL, USA, 33612</aff><aff id="A53"><label>53</label>Samuel Oschin Comprehensive Cancer Center Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA, 90048</aff><aff id="A54"><label>54</label>Gynecological Oncology Unit, The Royal Marsden Hospital, London, SW3 6JJ, United Kingdom</aff><aff id="A55"><label>55</label>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland, 70-115</aff><aff id="A56"><label>56</label>Department of Epidemiology and Biostatistics, Karolinska Istitutet, Stockholm, Sweden, 171-77</aff><aff id="A57"><label>57</label>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, HB 5006, Norway</aff><aff id="A58"><label>58</label>Department of Clinical Medicine, University of Bergen, 5006, Bergen, Norway</aff><aff id="A59"><label>59</label>Clinics of Obstetrics and Gynaecology, Hannover Medical School, 30625, Hannover, Germany</aff><aff id="A60"><label>60</label>Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, OR, USA, 97239</aff><aff id="A61"><label>61</label>The Juliane Marie Centre, Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen, 2100, Denmark</aff><aff id="A62"><label>62</label>Department of Pathology, Molecular Unit, Herlev Hospital, University of Copenhagen, Denmark, 2730</aff><aff id="A63"><label>63</label>Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100, Copenhagen, Denmark</aff><aff id="A64"><label>64</label>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, 464-8681, Japan</aff><aff id="A65"><label>65</label>Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA, 33612</aff><aff id="A66"><label>66</label>Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA, 55905</aff><aff id="A67"><label>67</label>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA, 90048</aff><aff id="A68"><label>68</label>Section of Medicine, Institute of Cancer Research, Sutton, SM2 5NG, UK</aff><aff id="A69"><label>69</label>Department of Popluation Health Research, Alberta Health Services-Cancer Care, Calgary, Alberta, Canada and Departments of Medical Genetics and Oncology, University of Calgary, Calgary, AB, Canada, T2N 2T9</aff><aff id="A70"><label>70</label>Department of Urology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</aff><aff id="A71"><label>71</label>Department of Obsterics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550, Japan</aff><aff id="A72"><label>72</label>Vesalius Research Center, VIB, 3000, Leuven, Belgium</aff><aff id="A73"><label>73</label>Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000, Leuven, Belgium</aff><aff id="A74"><label>74</label>Cancer Control Research, BC Cancer Agency, Vancouver, BC, Canada, G12 0YN</aff><aff id="A75"><label>75</label>Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10021</aff><aff id="A76"><label>76</label>College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA, 77044</aff><aff id="A77"><label>77</label>Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia</aff><aff id="A78"><label>78</label>Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</aff><aff id="A79"><label>79</label>Department of Cancer Epidemiology and Prevention, The Maria Sklodowska-Curie Memorial Cancer Center, 02-781, Warsaw, Poland</aff><aff id="A80"><label>80</label>Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 77030</aff><aff id="A81"><label>81</label>Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA, 96813</aff><aff id="A82"><label>82</label>Department of Gynaecology, Radboud University Medical Centre, Nijmegen, HB 6500, Netherlands</aff><aff id="A83"><label>83</label>Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford CA, USA, 94305</aff><aff id="A84"><label>84</label>Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, ON, M5T 3M7, Canada</aff><aff id="A85"><label>85</label>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, M5G 1X5</aff><aff id="A86"><label>86</label>Women's Cancer Research Program, Magee-Womens Research Institute and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA, 15213</aff><aff id="A87"><label>87</label>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA, 14263</aff><aff id="A88"><label>88</label>Department of Gynecologic Oncology, Aichi Cancer Center Central Hospital, Nagoya, Aichi, Nagoya, 464-8681, Japan</aff><aff id="A89"><label>89</label>Women's College Research Institute, University of Toronto, Toronto, Ontario, Canada, M5G 1N8</aff><aff id="A90"><label>90</label>Department of Pathology, Rigshospitalet, University of Copenhagen, 2100, Denmark</aff><aff id="A91"><label>91</label>The University of Texas School of Public Health, Houston, TX, USA, 77030</aff><aff id="A92"><label>92</label>USC Epigenome Center, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, 90089</aff><aff id="A93"><label>93</label>Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA, 14263</aff><aff id="A94"><label>94</label>Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, 10065</aff><aff id="A95"><label>95</label>Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA, 97239</aff><aff id="A96"><label>96</label>Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA, 97239</aff><aff id="A97"><label>97</label>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA, 02115</aff><aff id="A98"><label>98</label>Channing Laboratory, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA, 02115</aff><aff id="A99"><label>99</label>Department of Epidemiology and Public Health, Yale University School of Public Health and School of Medicine, New Haven, CT, USA, 06520</aff><aff id="A100"><label>100</label>Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, 98109</aff><aff id="A101"><label>101</label>Department of Epidemiology, University of Washington, Seattle, WA, USA, 98109</aff><aff id="A102"><label>102</label>Institut für Humangenetik Wiesbaden, 65187, Wiesbaden, Germany</aff><aff id="A103"><label>103</label>Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA, 55905</aff><aff id="A104"><label>104</label>Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, VIC 3053, Australia</aff><aff id="A105"><label>105</label>Department of Gynecologic Oncology, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, 02-781</aff><aff id="A106"><label>106</label>Pediatrics Epidemiology Center, College of Medicine, University of South Florida, Tampa, FL, USA, 33612</aff><aff id="A107"><label>107</label>Department of Obstetrics and Gynecology, University of Ulm, Ulm, 89081, Germany</aff><aff id="A108"><label>108</label>Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA, 27708</aff><aff id="A109"><label>109</label>Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA, 55905</aff><aff id="A110"><label>110</label>Shanghai Cancer Institute, Shanghai, China, 2200-25</aff><aff id="A111"><label>111</label>Department of Epidemiology, Center for Cancer Genetics Research and Prevention, School of Medicine, University of California Irvine, Irvine, California, USA, 92697</aff><aff id="A112"><label>112</label>Department of Statistical Science, Duke University, Durham, NC, USA, 27708</aff><aff id="A113"><label>113</label>Cancer Prevention, Detection and Control Research Program, Duke Cancer Institute, Durham, North Carolina, USA, 27708-0251</aff><aff id="A114"><label>114</label>Department of Obstetrics and Gynecology, Duke Comprehensive Cancer Center, Durham, NC, USA, 27708</aff><aff id="A115"><label>115</label>Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA, 66160</aff><author-notes><corresp id="FN1">Correspondence: Jennifer Permuth-Wey, PhD, Moffitt Cancer Center, 12902 Magnolia Dr., MRC-CANT, Tampa, Florida 33612, <email>Jenny.Wey@moffitt.org</email> Telephone: 813-745-5744, Fax: 813-745-6525; Thomas A. Sellers, PhD, Moffitt Cancer Center, 12902 Magnolia Dr, Tampa, Florida 33612, <email>Thomas.Sellers@moffitt.org</email>, Telephone: 813-745-1315, Fax: 813-449-8126; Simon Gayther, PhD, University of Southern California/Keck School of Medicine, Harlyne Norris Research Tower 1450 Biggy Street Los Angeles, CA 90033, <email>gayther@usc.edu</email>, Telephone: 323 442-8112, Fax: 323 442-7787</corresp><fn id="FN2" fn-type="equal"><label>*</label><p>contributed equally to this manuscript</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>21</day><month>6</month><year>2013</year></pub-date><pub-date pub-type="ppub"><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>12</day><month>7</month><year>2013</year></pub-date><volume>4</volume><fpage>1627</fpage><lpage>1627</lpage><pmc-comment>elocation-id from pubmed: 10.1038/ncomms2613</pmc-comment>
<permissions><license><license-p>Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: <ext-link ext-link-type="uri" xlink:href="http://www.nature.com/authors/editorial_policies/license.html#terms">http://www.nature.com/authors/editorial_policies/license.html#terms</ext-link></license-p></license></permissions><abstract><p id="P1">Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3′ untranslated region at putative microRNA (miRNA) binding sites represent functional targets that influence EOC susceptibility. Here, we evaluate the association between 767 miRNA binding site single nucleotide polymorphisms (miRSNPs) and EOC risk in 18,174 EOC cases and 26,134 controls from 43 studies genotyped through the Collaborative Oncological Gene-environment Study. We identify several miRSNPs associated with invasive serous EOC risk (OR=1.12, <italic>P</italic>=10<sup>−8</sup>) mapping to an inversion polymorphism at 17q21.31. Additional genotyping of non-miRSNPs at 17q21.31 reveals stronger signals outside the inversion (<italic>P</italic>=10<sup>−10</sup>). Variation at 17q21.31 associates with neurological diseases, and our collaboration is the first to report an association with EOC susceptibility. An integrated molecular analysis in this region provides evidence for <italic>ARHGAP27</italic> and <italic>PLEKHM1</italic> as candidate EOC susceptibility genes.</p></abstract></article-meta></front><floats-group><fig id="F1" orientation="portrait" position="float"><label>Figure 1</label><caption><title>Regional association plot for genotyped and imputed SNPs at 17q21.31</title><p>The middle portion of the plot contains the region of the inversion polymorphism (ch 17: 43,624,578-44,525,051, hg build 37), with the four blue dots representing the candidate miRSNPs (rs4640231, rs1052587, and rs17574361) and the tagSNP, rs916793. rs1052587 in the 3′UTR of <italic>MAPT</italic> has the strongest signal (P=4.6×10<sup>−8</sup>) among the miRSNPs. The cluster on the left side of the plot (around 43.5 MB) contains highly correlated SNPs (r<sup>2</sup>=0.99), including three directly genotyped intronic SNPs, rs2077606 and rs17631303 in <italic>PLEKHM1</italic> (P=3.9 × 10<sup>−10</sup> and P=4.7 × 10<sup>−10</sup>, respectively), and rs12942666 in ARHGAP27 (P=1.0 × 10<sup>−9</sup>). The linkage disequilibrium between each plotted SNP and the top-ranked SNP in the region with the best clustering, rs12942666, is depicted by the color scheme; the deeper the color red, the stronger the correlation between the plotted SNP and rs12942666. The top miRSNP, rs1052587, is moderately correlated (r<sup>2</sup>=0.76) with rs2077606, rs17631303, and rs12942666 in our study population. (n=8,371 invasive serous cases and n= 23,491 controls, of European ancestry).</p></caption><graphic xlink:href="nihms447293f1"></graphic></fig><fig id="F2" orientation="portrait" position="float"><label>Figure 2</label><caption><title>Expression and methylation analyses at the 17q21.31 ovarian cancer susceptibility locus</title><p><bold>(a)</bold> Genomic map and LD structure. The location and approximate size of 17 known protein coding genes (grey) and one microRNA (blue) in the region are shown relative to the location of rs12942666. Orange indicates the location of the inversion polymorphism, and green indicates the region outside the inversion.</p><p><bold>(b)</bold> Gene expression (EOC and normal cell lines). Gene expression analysis in Epithelial Ovarian Cancer (EOC) cell lines (T; n=51) compared to normal ovarian surface epithelial cells (OSECs) and fallopian tube secretory epithelial cells (FTSEC) (N; n=73) (* p<0.05, **p<0.01, ***p<0.001).</p><p><bold>(c)</bold> Gene expression (Primary EOCs and Normal Tissue). Boxplots of The Cancer Genome Atlas (TCGA) Affymetrix U133A-array based gene expression in primary high-grade serous ovarian tumors (T; n=568) and normal fallopian tube tissues (N; n=8). Where data were not available in TCGA, gene expression data from the Gene Expression Omnibus series GSE18520 dataset containing 53 high-grade serous tumors and 10 normal ovarian tissues are shown (indicated by a red asterisk).</p><p><bold>(d)</bold> Methylation (Primary Tumors and Normal Tissue). Methylation analysis of 106 high-grade serous ovarian tumors compared to normal ovarian tissues (n=7). Methylation data were generated for CpG site(s) associated with each gene using the Illumina 450 methylation array. Pairwise analysis of methylation for an individual CpG for each gene is based on the CpG with most significant inverse relationship to gene expression (i.e. cis negative), for a subset of 43 tumors having available gene expression data. Statistically significant cis-negative probes are indicated by a red open circle.</p><p><bold>(e)</bold> Expression quantitative trait locus (eQTL) analysis (OSECs/FTSECs). eQTL analysis comparing expression for each gene to genotype for the most statistically significant SNP at 17q21.31 (rs12942666), for 73 normal OSEC/FTSEC lines. Data are presented as box plots comparing expression levels in cases carrying rare homozygotes/heterozygotes, with cases homozygous for the common allele.</p><p><bold>(f)</bold> Expression quantitative trait locus (eQTL) analysis (Primary EOCs). eQTL analysis comparing expression for each gene to genotype using level 3 gene expression profiling data from Agilent 244K custom arrays and level 2 genotype data from the Illumina 1M-Duo BeadChip for 568 high-grade serous ovarian cancer patients from TCGA. In all panels * p<0.05, **p<0.01, *** p<0.001. Grey X's indicate data not available. Here, genotype data for rs2077606 is used (rather than rs12942666) because rs12942666 was not genotyped in the TCGA dataset.</p><p><bold>(g)</bold> Methylation quantitative trait locus (mQTL) analysis (Primary EOCs). mQTL analysis showing methylation status in 227 high-grade serous EOCs relative to rs12942666 genotype.</p></caption><graphic xlink:href="nihms447293f2"></graphic></fig><fig id="F3" orientation="portrait" position="float"><label>Figure 3</label><caption><title>eQTL associations between the rs2077606 susceptibility SNP at 17q21</title><p><bold>(a)</bold> Analysis of the chromatin landscape at <italic>ARHGAP27</italic> and <italic>PLEKHM1</italic> in normal ovarian surface epithelial and fallopian tube secretory epithelial cells (OSECs/FTSECs) by formaldehyde assisted isolation of regulatory elements sequencing (FAIRE-seq). Alignment with ENCODE FAIRE-seq tracks (shown) and ChIP-seq tracks (not shown) from non-EOC related cell lines reveals open chromatin peaks corresponding to (a) promoters (b) CTCF insulator binding sites and (c) H3K4me3 signals, suggestive of a dynamic regulatory region. An H3K4me3 signal at a coding <italic>ARHGAP27</italic> mRNA variant (c) located between the genes is highly pronounced in OSEC/FTSEC, suggesting tissue-specific expression and function. Several of the top-ranking SNPs fall within transcription factor binding sites (TFFS) (<xref rid="SD1" ref-type="supplementary-material">Supplementary Table S2</xref>). rs12942666 did not coincide with TFBS, but tightly linked SNPs, rs12946900 and rs2077606 fell within predicted binding sites for SPIB and ZEB1, respectively.</p><p><bold>(b)</bold> We analyzed the expression of <italic>SPIB</italic> and <italic>ZEB1</italic> in primary high-grade serous tumors from TCGA and found (i) no significant change in SPIB expression but (ii) significant down-regulation of <italic>ZEB1</italic> in tumors compared to normal tissues. (iii) QPCR analysis of <italic>ZEB1</italic> expression in 73 OCPT and 50 EOC cell lines replicated the finding that <italic>ZEB1</italic> expression is lower in cancer cell lines compared to normal precursor tissues. (c) eQTL analysis in OSECs/FTSECs for different alleles of rs2077606. There was a (i) significant eQTL for <italic>ARHGAP27</italic>, with the minor (A) allele being associated with increased <italic>ARHGAP27</italic> expression (<italic>P</italic>=0.034), (ii) no evidence of an association between rs2077606 genotypes and <italic>ARHGAP27</italic> expression in lymphoblastoid cell lines suggesting this association may be tissue-specific. (iii) We observed a borderline significant eQTL association between <italic>ZEB1</italic> mRNA and rs2077606 in tumors from TCGA, with the minor risk allele also associated with lower expression.</p></caption><graphic xlink:href="nihms447293f3"></graphic></fig><table-wrap id="T1" position="float" orientation="landscape"><label>Table 1</label><caption><title>Tests of association by histological subtype for directly genotyped and imputed SNPs at 17q21.31 most strongly associated with invasive epithelial ovarian cancer risk among Europeans</title></caption><table frame="hsides" rules="groups"><thead><tr><th valign="middle" align="center" rowspan="1" colspan="1">SNP Major>minor allele allele</th><th valign="middle" align="center" rowspan="1" colspan="1">Coordinate<sup><xref rid="TFN2" ref-type="table-fn">a</xref></sup></th><th valign="middle" align="center" rowspan="1" colspan="1">MAF</th><th valign="middle" align="center" rowspan="1" colspan="1">Subtype</th><th valign="middle" align="center" rowspan="1" colspan="1">Number of cases (versus 23,491 controls)</th><th valign="middle" align="center" rowspan="1" colspan="1">Per-allele OR (95% CI)<sup><xref rid="TFN3" ref-type="table-fn">b</xref></sup></th><th valign="middle" align="left" rowspan="1" colspan="1">P-value</th></tr></thead><tbody><tr><td align="center" valign="middle" rowspan="1" colspan="1">rs1052587<sup><xref rid="TFN4" ref-type="table-fn">c</xref></sup> (T>C)</td><td align="center" valign="middle" rowspan="1" colspan="1">44102604</td><td align="center" valign="middle" rowspan="1" colspan="1">0.22</td><td align="center" valign="middle" rowspan="1" colspan="1">All Invasives</td><td align="center" valign="middle" rowspan="1" colspan="1">14,533</td><td align="center" valign="middle" rowspan="1" colspan="1">1.10 (1.06-1.13)</td><td align="left" valign="middle" rowspan="1" colspan="1">1.9 × 10<sup>−7</sup></td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Serous</td><td align="center" valign="middle" rowspan="1" colspan="1">8,371</td><td align="center" valign="middle" rowspan="1" colspan="1">1.12 (1.08-1.17)</td><td align="left" valign="middle" rowspan="1" colspan="1">4.6 × 10<sup>−8</sup></td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Endometrioid</td><td align="center" valign="middle" rowspan="1" colspan="1">2,068</td><td align="center" valign="middle" rowspan="1" colspan="1">1.11 (1.04-1.19)</td><td align="left" valign="middle" rowspan="1" colspan="1">5.2 × 10<sup>−3</sup></td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Clear Cell</td><td align="center" valign="middle" rowspan="1" colspan="1">1,025</td><td align="center" valign="middle" rowspan="1" colspan="1">0.98 (0.88-1.09)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.68</td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Mucinous</td><td align="center" valign="middle" rowspan="1" colspan="1">944</td><td align="center" valign="middle" rowspan="1" colspan="1">1.07 (0.96-1.20)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.22</td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1">rs12942666<sup><xref rid="TFN5" ref-type="table-fn">d</xref></sup> (A>G)</td><td align="center" valign="middle" rowspan="1" colspan="1">43499839</td><td align="center" valign="middle" rowspan="1" colspan="1">0.22</td><td align="center" valign="middle" rowspan="1" colspan="1">All Invasives</td><td align="center" valign="middle" rowspan="1" colspan="1">14,533</td><td align="center" valign="middle" rowspan="1" colspan="1">1.11 (1.07-1.15)</td><td align="left" valign="middle" rowspan="1" colspan="1">3.3 × 10<sup>−8</sup></td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Serous</td><td align="center" valign="middle" rowspan="1" colspan="1">8,371</td><td align="center" valign="middle" rowspan="1" colspan="1">1.15 (1.11-1.20)</td><td align="left" valign="middle" rowspan="1" colspan="1">1.0 × 10<sup>−9</sup></td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Endometrioid</td><td align="center" valign="middle" rowspan="1" colspan="1">2,068</td><td align="center" valign="middle" rowspan="1" colspan="1">1.10 (1.02-1.18)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.04</td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Clear Cell</td><td align="center" valign="middle" rowspan="1" colspan="1">1,025</td><td align="center" valign="middle" rowspan="1" colspan="1">1.04 (0.92-1.14)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.61</td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Mucinous</td><td align="center" valign="middle" rowspan="1" colspan="1">944</td><td align="center" valign="middle" rowspan="1" colspan="1">1.04 (0.92-1.16)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.55</td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1">rs2960000<sup><xref rid="TFN6" ref-type="table-fn">e</xref></sup> (T>C)</td><td align="center" valign="middle" rowspan="1" colspan="1">43534353</td><td align="center" valign="middle" rowspan="1" colspan="1">0.18</td><td align="center" valign="middle" rowspan="1" colspan="1">All Invasives</td><td align="center" valign="middle" rowspan="1" colspan="1">14,533</td><td align="center" valign="middle" rowspan="1" colspan="1">1.12 (1.08-1.16)</td><td align="left" valign="middle" rowspan="1" colspan="1">4.2 × 10<sup>−9</sup></td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Serous</td><td align="center" valign="middle" rowspan="1" colspan="1">8,371</td><td align="center" valign="middle" rowspan="1" colspan="1">1.16 (1.12-1.20)</td><td align="left" valign="middle" rowspan="1" colspan="1">3.3 × 10<sup>−10</sup></td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Endometrioid</td><td align="center" valign="middle" rowspan="1" colspan="1">2,068</td><td align="center" valign="middle" rowspan="1" colspan="1">1.12 (1.03-1.20)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.01</td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Clear Cell</td><td align="center" valign="middle" rowspan="1" colspan="1">1,025</td><td align="center" valign="middle" rowspan="1" colspan="1">1.05 (0.93-1.16)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.44</td></tr><tr><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1"></td><td align="center" valign="middle" rowspan="1" colspan="1">Mucinous</td><td align="center" valign="middle" rowspan="1" colspan="1">944</td><td align="center" valign="middle" rowspan="1" colspan="1">1.03 (0.90-1.15)</td><td align="left" valign="middle" rowspan="1" colspan="1">0.65</td></tr></tbody></table><table-wrap-foot><fn id="TFN1"><p>Abbreviations: MAF=minor allele frequency in controls; OR=Odds ratio; CI=Confidence intervals</p></fn><fn id="TFN2"><label>a</label><p>Genome build NCBI B37/human genome build 19 assembly.</p></fn><fn id="TFN3"><label>b</label><p>OR and 95% CI per copy of the minor allele, with adjustment for the first five eigenvalues from principal components analysis.</p></fn><fn id="TFN4"><label>c</label><p>rs1052587 is the most statistically significant miRNA binding site SNP among all invasives and serous; it resides in a putative miRNA binding site between microtubule-associated protein tau (<italic>MAPT</italic>) and miR- 34a-5p (chr 1:9134225-9134425).</p></fn><fn id="TFN5"><label>d</label><p>rs12942666 is a SNP at 17q21.31 that was directly genotyped as part of COGs; it is in strong linkage disequilibrium (r<sup>2</sup>=0.99) with two other 17q21.31 SNPs that were directly genotyped but had less optimal clustering: rs2077606 (P=3.9 × 10<sup>−10</sup> for the serous subtype) and rs17631303 (P=4.7×10<sup>−10</sup> for the serous subtype).</p></fn><fn id="TFN6"><label>e</label><p>rs2960000 represents the most statistically significant SNP at 17q21.31 (among all invasives) that was imputed from the 1000 genome Project reference panel with an R-squared quality metric of 95% or greater (<ext-link ext-link-type="uri" xlink:href="http://www.1000genomes.org/page.php">http://www.1000genomes.org/page.php</ext-link>).</p></fn></table-wrap-foot></table-wrap></floats-group></pmc><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Biélorussie</li><li>Canada</li><li>Danemark</li><li>Japon</li><li>Malaisie</li><li>Norvège</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Alberta</li><li>Angleterre</li><li>Angleterre de l'Est</li><li>Bade-Wurtemberg</li><li>Basse-Saxe</li><li>Bavière</li><li>Californie</li><li>District de Karlsruhe</li><li>District de Moyenne-Franconie</li><li>District de Tübingen</li><li>Floride</li><li>Hovedstaden</li><li>Ontario</li><li>Washington (État)</li></region><settlement><li>Calgary</li><li>Cambridge</li><li>Copenhague</li><li>Erlangen</li><li>Hanovre</li><li>Heidelberg</li><li>Los Angeles</li><li>Seattle</li><li>Tampa</li><li>Toronto</li><li>Ulm</li></settlement><orgName><li>Université d'Ulm</li><li>Université de Calgary</li><li>Université de Californie du Sud</li><li>Université de Cambridge</li><li>Université de Floride du Sud</li><li>Université de Toronto</li><li>Université de Washington</li></orgName></list><tree><noCountry><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><name sortKey="Armasu, Sebastian M" sort="Armasu, Sebastian M" uniqKey="Armasu S" first="Sebastian M." last="Armasu">Sebastian M. Armasu</name><name sortKey="Bacot, Francois" sort="Bacot, Francois" uniqKey="Bacot F" first="François" last="Bacot">François Bacot</name><name sortKey="Bandera, Elisa V" sort="Bandera, Elisa V" uniqKey="Bandera E" first="Elisa V." last="Bandera">Elisa V. Bandera</name><name sortKey="Barnholtz Sloan, Jill" sort="Barnholtz Sloan, Jill" uniqKey="Barnholtz Sloan J" first="Jill" last="Barnholtz-Sloan">Jill Barnholtz-Sloan</name><name sortKey="Berchuck, Andrew" sort="Berchuck, Andrew" uniqKey="Berchuck A" first="Andrew" last="Berchuck">Andrew Berchuck</name><name sortKey="Birrer, Michael J" sort="Birrer, Michael J" uniqKey="Birrer M" first="Michael J." last="Birrer">Michael J. Birrer</name><name sortKey="Bloom, Greg" sort="Bloom, Greg" uniqKey="Bloom G" first="Greg" last="Bloom">Greg Bloom</name><name sortKey="Brinton, Louise A" sort="Brinton, Louise A" uniqKey="Brinton L" first="Louise A." last="Brinton">Louise A. Brinton</name><name sortKey="Brooks Wilson, Angela" sort="Brooks Wilson, Angela" uniqKey="Brooks Wilson A" first="Angela" last="Brooks-Wilson">Angela Brooks-Wilson</name><name sortKey="Butzow, Ralf" sort="Butzow, Ralf" uniqKey="Butzow R" first="Ralf" last="Butzow">Ralf Butzow</name><name sortKey="Cai, Qiuyin" sort="Cai, Qiuyin" uniqKey="Cai Q" first="Qiuyin" last="Cai">Qiuyin Cai</name><name sortKey="Chanock, Stephen" sort="Chanock, Stephen" uniqKey="Chanock S" first="Stephen" last="Chanock">Stephen Chanock</name><name sortKey="Chen, Y Ann" sort="Chen, Y Ann" uniqKey="Chen Y" first="Y. Ann" last="Chen">Y. Ann Chen</name><name sortKey="Chen, Zhihua" sort="Chen, Zhihua" uniqKey="Chen Z" first="Zhihua" last="Chen">Zhihua Chen</name><name sortKey="Cheng, Jin Q" sort="Cheng, Jin Q" uniqKey="Cheng J" first="Jin Q." last="Cheng">Jin Q. Cheng</name><name sortKey="Cicek, Mine S" sort="Cicek, Mine S" uniqKey="Cicek M" first="Mine S." last="Cicek">Mine S. Cicek</name><name sortKey="Cook, Linda S" sort="Cook, Linda S" uniqKey="Cook L" first="Linda S." last="Cook">Linda S. Cook</name><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><name sortKey="Cramer, Daniel W" sort="Cramer, Daniel W" uniqKey="Cramer D" first="Daniel W." last="Cramer">Daniel W. Cramer</name><name sortKey="Cunningham, Julie M" sort="Cunningham, Julie M" uniqKey="Cunningham J" first="Julie M." last="Cunningham">Julie M. Cunningham</name><name sortKey="Dansonka Mieszkowska, Agnieszka" sort="Dansonka Mieszkowska, Agnieszka" uniqKey="Dansonka Mieszkowska A" first="Agnieszka" last="Dansonka-Mieszkowska">Agnieszka Dansonka-Mieszkowska</name><name sortKey="Despierre, Evelyn" sort="Despierre, Evelyn" uniqKey="Despierre E" first="Evelyn" last="Despierre">Evelyn Despierre</name><name sortKey="Doherty, Jennifer A" sort="Doherty, Jennifer A" uniqKey="Doherty J" first="Jennifer A" last="Doherty">Jennifer A. Doherty</name><name sortKey="Edwards, Robert" sort="Edwards, Robert" uniqKey="Edwards R" first="Robert" last="Edwards">Robert Edwards</name><name sortKey="Fenstermacher, David A" sort="Fenstermacher, David A" uniqKey="Fenstermacher D" first="David A." last="Fenstermacher">David A. Fenstermacher</name><name sortKey="Fridley, Brooke L" sort="Fridley, Brooke L" uniqKey="Fridley B" first="Brooke L." last="Fridley">Brooke L. Fridley</name><name sortKey="G Rski, Bohdan" sort="G Rski, Bohdan" uniqKey="G Rski B" first="Bohdan" last="G Rski">Bohdan G Rski</name><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><name sortKey="Gayther, Simon A" sort="Gayther, Simon A" uniqKey="Gayther S" first="Simon A." last="Gayther">Simon A. Gayther</name><name sortKey="Gonzalez Bosquet, Jesus" sort="Gonzalez Bosquet, Jesus" uniqKey="Gonzalez Bosquet J" first="Jesus" last="Gonzalez-Bosquet">Jesus Gonzalez-Bosquet</name><name sortKey="Goode, Ellen L" sort="Goode, Ellen L" uniqKey="Goode E" first="Ellen L." last="Goode">Ellen L. Goode</name><name sortKey="Goodman, Marc T" sort="Goodman, Marc T" uniqKey="Goodman M" first="Marc T." last="Goodman">Marc T. Goodman</name><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><name sortKey="Hoatlin, Maureen" sort="Hoatlin, Maureen" uniqKey="Hoatlin M" first="Maureen" last="Hoatlin">Maureen Hoatlin</name><name sortKey="Iversen, Edwin" sort="Iversen, Edwin" uniqKey="Iversen E" first="Edwin" last="Iversen">Edwin Iversen</name><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><name sortKey="Jim, Heather" sort="Jim, Heather" uniqKey="Jim H" first="Heather" last="Jim">Heather Jim</name><name sortKey="Kalli, Kimberly R" sort="Kalli, Kimberly R" uniqKey="Kalli K" first="Kimberly R." last="Kalli">Kimberly R. Kalli</name><name sortKey="Karevan, Rod" sort="Karevan, Rod" uniqKey="Karevan R" first="Rod" last="Karevan">Rod Karevan</name><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name><name sortKey="Konecny, Gottfried E" sort="Konecny, Gottfried E" uniqKey="Konecny G" first="Gottfried E." last="Konecny">Gottfried E. Konecny</name><name sortKey="Kupryjanczyk, Jolanta" sort="Kupryjanczyk, Jolanta" uniqKey="Kupryjanczyk J" first="Jolanta" last="Kupryjanczyk">Jolanta Kupryjanczyk</name><name sortKey="Lambrechts, Sandrina" sort="Lambrechts, Sandrina" uniqKey="Lambrechts S" first="Sandrina" last="Lambrechts">Sandrina Lambrechts</name><name sortKey="Lancaster, Johnathan M" sort="Lancaster, Johnathan M" uniqKey="Lancaster J" first="Johnathan M." last="Lancaster">Johnathan M. Lancaster</name><name sortKey="Larson, Melissa C" sort="Larson, Melissa C" uniqKey="Larson M" first="Melissa C." last="Larson">Melissa C. Larson</name><name sortKey="Lawrenson, Kate" sort="Lawrenson, Kate" uniqKey="Lawrenson K" first="Kate" last="Lawrenson">Kate Lawrenson</name><name sortKey="Le, Nhu D" sort="Le, Nhu D" uniqKey="Le N" first="Nhu D." last="Le">Nhu D. Le</name><name sortKey="Lee, Janet" sort="Lee, Janet" uniqKey="Lee J" first="Janet" last="Lee">Janet Lee</name><name sortKey="Lee, Nathan" sort="Lee, Nathan" uniqKey="Lee N" first="Nathan" last="Lee">Nathan Lee</name><name sortKey="Leminen, Arto" sort="Leminen, Arto" uniqKey="Leminen A" first="Arto" last="Leminen">Arto Leminen</name><name sortKey="Levine, Douglas A" sort="Levine, Douglas A" uniqKey="Levine D" first="Douglas A." last="Levine">Douglas A. Levine</name><name sortKey="Liang, Dong" sort="Liang, Dong" uniqKey="Liang D" first="Dong" last="Liang">Dong Liang</name><name sortKey="Lin, Hui Yi" sort="Lin, Hui Yi" uniqKey="Lin H" first="Hui-Yi" last="Lin">Hui-Yi Lin</name><name sortKey="Lin, Jie" sort="Lin, Jie" uniqKey="Lin J" first="Jie" last="Lin">Jie Lin</name><name sortKey="Lu, Karen H" sort="Lu, Karen H" uniqKey="Lu K" first="Karen H." last="Lu">Karen H. Lu</name><name sortKey="Lubi Ski, Jan" sort="Lubi Ski, Jan" uniqKey="Lubi Ski J" first="Jan" last="Lubi Ski">Jan Lubi Ski</name><name sortKey="Lurie, Galina" sort="Lurie, Galina" uniqKey="Lurie G" first="Galina" last="Lurie">Galina Lurie</name><name sortKey="Mcguire, Valerie" sort="Mcguire, Valerie" uniqKey="Mcguire V" first="Valerie" last="Mcguire">Valerie Mcguire</name><name sortKey="Modugno, Francesmary" sort="Modugno, Francesmary" uniqKey="Modugno F" first="Francesmary" last="Modugno">Francesmary Modugno</name><name sortKey="Monteiro, Alvaro N A" sort="Monteiro, Alvaro N A" uniqKey="Monteiro A" first="Alvaro N. A." last="Monteiro">Alvaro N. A. Monteiro</name><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B." last="Moysich">Kirsten B. Moysich</name><name sortKey="Ness, Roberta B" sort="Ness, Roberta B" uniqKey="Ness R" first="Roberta B." last="Ness">Roberta B. Ness</name><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><name sortKey="Odunsi, Kunle" sort="Odunsi, Kunle" uniqKey="Odunsi K" first="Kunle" last="Odunsi">Kunle Odunsi</name><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H." last="Olson">Sara H. Olson</name><name sortKey="Orlow, Irene" sort="Orlow, Irene" uniqKey="Orlow I" first="Irene" last="Orlow">Irene Orlow</name><name sortKey="Pearce, Celeste L" sort="Pearce, Celeste L" uniqKey="Pearce C" first="Celeste L" last="Pearce">Celeste L. Pearce</name><name sortKey="Pejovic, Tanja" sort="Pejovic, Tanja" uniqKey="Pejovic T" first="Tanja" last="Pejovic">Tanja Pejovic</name><name sortKey="Pelttari, Liisa M" sort="Pelttari, Liisa M" uniqKey="Pelttari L" first="Liisa M." last="Pelttari">Liisa M. Pelttari</name><name sortKey="Permuth Wey, Jennifer" sort="Permuth Wey, Jennifer" uniqKey="Permuth Wey J" first="Jennifer" last="Permuth-Wey">Jennifer Permuth-Wey</name><name sortKey="Phelan, Catherine M" sort="Phelan, Catherine M" uniqKey="Phelan C" first="Catherine M." last="Phelan">Catherine M. Phelan</name><name sortKey="Pike, Malcolm C" sort="Pike, Malcolm C" uniqKey="Pike M" first="Malcolm C." last="Pike">Malcolm C. Pike</name><name sortKey="Poole, Elizabeth M" sort="Poole, Elizabeth M" uniqKey="Poole E" first="Elizabeth M." last="Poole">Elizabeth M. Poole</name><name sortKey="Qu, Xiaotao" sort="Qu, Xiaotao" uniqKey="Qu X" first="Xiaotao" last="Qu">Xiaotao Qu</name><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J." last="Ramus">Susan J. 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