La maladie de Parkinson au Canada (serveur d'exploration)

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Psychomotor Behavior: A Practical Approach in Drosophila

Identifieur interne : 000071 ( Pmc/Checkpoint ); précédent : 000070; suivant : 000072

Psychomotor Behavior: A Practical Approach in Drosophila

Auteurs : Konstantin G. Iliadi [Canada] ; Oxana B. Gluscencova [Canada] ; Gabrielle L. Boulianne [Canada]

Source :

RBID : PMC:5005351

Abstract

Psychomotor behaviors are governed by fine relationships between physical activity and cognitive functions. Disturbances in psychomotor development and performance are a hallmark of many mental illnesses and often appear as observable and measurable behaviors. Here, we describe a new method called an “equilibrist test,” which can be used to quantify psychomotor learning and performance in Drosophila. We also show how this test can be used to quantify motor disturbances at relatively early stages in the development of neurodegenerative diseases.


Url:
DOI: 10.3389/fpsyt.2016.00153
PubMed: 27630583
PubMed Central: 5005351


Affiliations:


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PMC:5005351

Le document en format XML

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<publisher-name>Frontiers Media S.A.</publisher-name>
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</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27630583</article-id>
<article-id pub-id-type="pmc">5005351</article-id>
<article-id pub-id-type="doi">10.3389/fpsyt.2016.00153</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychiatry</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Psychomotor Behavior: A Practical Approach in
<italic>Drosophila</italic>
</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Iliadi</surname>
<given-names>Konstantin G.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
<uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/49850"></uri>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gluscencova</surname>
<given-names>Oxana B.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/362647"></uri>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Boulianne</surname>
<given-names>Gabrielle L.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
<uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/36244"></uri>
</contrib>
</contrib-group>
<aff id="aff1">
<sup>1</sup>
<institution>Program in Developmental and Stem Cell Biology, The Hospital For Sick Children</institution>
,
<addr-line>Toronto, ON</addr-line>
,
<country>Canada</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>Department of Molecular Genetics, University of Toronto</institution>
,
<addr-line>Toronto, ON</addr-line>
,
<country>Canada</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>Edited by: Frank Hirth, King’s College London, UK</p>
</fn>
<fn fn-type="edited-by">
<p>Reviewed by: Carlos M. Opazo, University of Melbourne, Australia; Bruno Van Swinderen, University of Queensland, Australia</p>
</fn>
<corresp content-type="corresp" id="cor1">*Correspondence: Konstantin G. Iliadi,
<email>iliadi@sickkids.ca</email>
; Gabrielle L. Boulianne,
<email>gboul@sickkids.ca</email>
</corresp>
<fn fn-type="other" id="fn001">
<p>Specialty section: This article was submitted to Molecular Psychiatry, a section of the journal Frontiers in Psychiatry</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>31</day>
<month>8</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="collection">
<year>2016</year>
</pub-date>
<volume>7</volume>
<elocation-id>153</elocation-id>
<history>
<date date-type="received">
<day>03</day>
<month>5</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>19</day>
<month>8</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright © 2016 Iliadi, Gluscencova and Boulianne.</copyright-statement>
<copyright-year>2016</copyright-year>
<copyright-holder>Iliadi, Gluscencova and Boulianne</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p>
</license>
</permissions>
<abstract>
<p>Psychomotor behaviors are governed by fine relationships between physical activity and cognitive functions. Disturbances in psychomotor development and performance are a hallmark of many mental illnesses and often appear as observable and measurable behaviors. Here, we describe a new method called an “equilibrist test,” which can be used to quantify psychomotor learning and performance in
<italic>Drosophila</italic>
. We also show how this test can be used to quantify motor disturbances at relatively early stages in the development of neurodegenerative diseases.</p>
</abstract>
<kwd-group>
<kwd>
<italic>Drosophila</italic>
</kwd>
<kwd>locomotion</kwd>
<kwd>psychomotor learning</kwd>
<kwd>neurodegeneration</kwd>
<kwd>behavior</kwd>
</kwd-group>
<funding-group>
<award-group>
<funding-source id="cn01">Canadian Institutes of Health Research
<named-content content-type="fundref-id">10.13039/501100000024</named-content>
</funding-source>
<award-id rid="cn01">FRN67130</award-id>
</award-group>
</funding-group>
<counts>
<fig-count count="6"></fig-count>
<table-count count="1"></table-count>
<equation-count count="0"></equation-count>
<ref-count count="31"></ref-count>
<page-count count="7"></page-count>
<word-count count="4487"></word-count>
</counts>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>Canada</li>
</country>
</list>
<tree>
<country name="Canada">
<noRegion>
<name sortKey="Iliadi, Konstantin G" sort="Iliadi, Konstantin G" uniqKey="Iliadi K" first="Konstantin G." last="Iliadi">Konstantin G. Iliadi</name>
</noRegion>
<name sortKey="Boulianne, Gabrielle L" sort="Boulianne, Gabrielle L" uniqKey="Boulianne G" first="Gabrielle L." last="Boulianne">Gabrielle L. Boulianne</name>
<name sortKey="Boulianne, Gabrielle L" sort="Boulianne, Gabrielle L" uniqKey="Boulianne G" first="Gabrielle L." last="Boulianne">Gabrielle L. Boulianne</name>
<name sortKey="Gluscencova, Oxana B" sort="Gluscencova, Oxana B" uniqKey="Gluscencova O" first="Oxana B." last="Gluscencova">Oxana B. Gluscencova</name>
</country>
</tree>
</affiliations>
</record>

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