Elucidating the structure of an infectious protein
Identifieur interne : 000018 ( Pmc/Checkpoint ); précédent : 000017; suivant : 000019Elucidating the structure of an infectious protein
Auteurs : Markus Zweckstetter [Allemagne] ; Jesús R. Requena [Espagne] ; Holger Wille [Canada]Source :
- PLoS Pathogens [ 1553-7366 ] ; 2017.
Url:
DOI: 10.1371/journal.ppat.1006229
PubMed: 28406976
PubMed Central: 5391083
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:5391083Le document en format XML
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<front><journal-meta><journal-id journal-id-type="nlm-ta">PLoS Pathog</journal-id>
<journal-id journal-id-type="iso-abbrev">PLoS Pathog</journal-id>
<journal-id journal-id-type="publisher-id">plos</journal-id>
<journal-id journal-id-type="pmc">plospath</journal-id>
<journal-title-group><journal-title>PLoS Pathogens</journal-title>
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<issn pub-type="ppub">1553-7366</issn>
<issn pub-type="epub">1553-7374</issn>
<publisher><publisher-name>Public Library of Science</publisher-name>
<publisher-loc>San Francisco, CA USA</publisher-loc>
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<article-meta><article-id pub-id-type="pmid">28406976</article-id>
<article-id pub-id-type="pmc">5391083</article-id>
<article-id pub-id-type="doi">10.1371/journal.ppat.1006229</article-id>
<article-id pub-id-type="publisher-id">PPATHOGENS-D-17-00037</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Pearls</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Biology and Life Sciences</subject>
<subj-group><subject>Zoology</subject>
<subj-group><subject>Animal Diseases</subject>
<subj-group><subject>Animal Prion Diseases</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Medicine and Health Sciences</subject>
<subj-group><subject>Infectious Diseases</subject>
<subj-group><subject>Prion Diseases</subject>
<subj-group><subject>Animal Prion Diseases</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Medicine and Health Sciences</subject>
<subj-group><subject>Infectious Diseases</subject>
<subj-group><subject>Zoonoses</subject>
<subj-group><subject>Prion Diseases</subject>
<subj-group><subject>Animal Prion Diseases</subject>
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</subj-group>
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</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Biology and Life Sciences</subject>
<subj-group><subject>Biochemistry</subject>
<subj-group><subject>Proteins</subject>
<subj-group><subject>Amyloid Proteins</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Research and Analysis Methods</subject>
<subj-group><subject>Crystallographic Techniques</subject>
<subj-group><subject>X-Ray Crystallography</subject>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Research and Analysis Methods</subject>
<subj-group><subject>Structural Characterization</subject>
<subj-group><subject>X-Ray Crystallography</subject>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Medicine and Health Sciences</subject>
<subj-group><subject>Infectious Diseases</subject>
<subj-group><subject>Prion Diseases</subject>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Medicine and Health Sciences</subject>
<subj-group><subject>Infectious Diseases</subject>
<subj-group><subject>Zoonoses</subject>
<subj-group><subject>Prion Diseases</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Biology and Life Sciences</subject>
<subj-group><subject>Molecular Biology</subject>
<subj-group><subject>Macromolecular Structure Analysis</subject>
<subj-group><subject>Protein Structure</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Biology and Life Sciences</subject>
<subj-group><subject>Biochemistry</subject>
<subj-group><subject>Proteins</subject>
<subj-group><subject>Protein Structure</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Medicine and Health Sciences</subject>
<subj-group><subject>Infectious Diseases</subject>
<subj-group><subject>Fungal Diseases</subject>
<subj-group><subject>Yeast Infections</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Biology and Life Sciences</subject>
<subj-group><subject>Biochemistry</subject>
<subj-group><subject>Proteins</subject>
<subj-group><subject>Cytoskeletal Proteins</subject>
<subj-group><subject>Microtubule-Associated Proteins</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
<subj-group subj-group-type="Discipline-v3"><subject>Biology and Life Sciences</subject>
<subj-group><subject>Cell Biology</subject>
<subj-group><subject>Cell Processes</subject>
<subj-group><subject>Cell Cycle and Cell Division</subject>
</subj-group>
</subj-group>
</subj-group>
</subj-group>
</article-categories>
<title-group><article-title>Elucidating the structure of an infectious protein</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Zweckstetter</surname>
<given-names>Markus</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff002"><sup>2</sup>
</xref>
<xref ref-type="aff" rid="aff003"><sup>3</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Requena</surname>
<given-names>Jesús R.</given-names>
</name>
<xref ref-type="aff" rid="aff004"><sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author"><contrib-id authenticated="true" contrib-id-type="orcid">http://orcid.org/0000-0001-5102-8706</contrib-id>
<name><surname>Wille</surname>
<given-names>Holger</given-names>
</name>
<xref ref-type="aff" rid="aff005"><sup>5</sup>
</xref>
<xref ref-type="aff" rid="aff006"><sup>6</sup>
</xref>
<xref ref-type="corresp" rid="cor001">*</xref>
</contrib>
</contrib-group>
<aff id="aff001"><label>1</label>
<addr-line>Deutsches Zentrum für Neurodegenerative Erkrankungen, Göttingen, Germany</addr-line>
</aff>
<aff id="aff002"><label>2</label>
<addr-line>Max Planck Institute for Biophysical Chemistry, Göttingen, Germany</addr-line>
</aff>
<aff id="aff003"><label>3</label>
<addr-line>University Medical Center Göttingen, University of Göttingen, Göttingen, Germany</addr-line>
</aff>
<aff id="aff004"><label>4</label>
<addr-line>CIMUS Biomedical Research Institute, University of Santiago de Compostela-IDIS, Santiago de Compostela, Spain</addr-line>
</aff>
<aff id="aff005"><label>5</label>
<addr-line>Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada</addr-line>
</aff>
<aff id="aff006"><label>6</label>
<addr-line>Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada</addr-line>
</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>True</surname>
<given-names>Heather L.</given-names>
</name>
<role>Editor</role>
<xref ref-type="aff" rid="edit1"></xref>
</contrib>
</contrib-group>
<aff id="edit1"><addr-line>Washington University School of Medicine, UNITED STATES</addr-line>
</aff>
<author-notes><fn fn-type="COI-statement" id="coi001"><p>The authors have declared that no competing interests exist.</p>
</fn>
<corresp id="cor001">* E-mail: <email>wille@ualberta.ca</email>
</corresp>
</author-notes>
<pub-date pub-type="epub"><day>13</day>
<month>4</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="collection"><month>4</month>
<year>2017</year>
</pub-date>
<volume>13</volume>
<issue>4</issue>
<elocation-id>e1006229</elocation-id>
<permissions><copyright-statement>© 2017 Zweckstetter et al</copyright-statement>
<copyright-year>2017</copyright-year>
<copyright-holder>Zweckstetter et al</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>
, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:href="ppat.1006229.pdf"></self-uri>
<funding-group><funding-statement>This work was supported by the Helmholtz-Alberta-Initiative on Neurodegenerative Disease Research (HAI-NDR SO-083), the Alberta Prion Research Institute (APRI 201100011, 201300012, and 201300024), the Alberta Livestock & Meat Agency (ALMA 2012A001R), EU FP7 222887 (Priority), and the Spanish Ministry of Industry and Competitiveness (BFU2013-48436-C2-1-P). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</funding-statement>
</funding-group>
<counts><fig-count count="1"></fig-count>
<table-count count="1"></table-count>
<page-count count="6"></page-count>
</counts>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Allemagne</li>
<li>Canada</li>
<li>Espagne</li>
</country>
<region><li>Basse-Saxe</li>
</region>
<settlement><li>Göttingen</li>
</settlement>
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<tree><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Zweckstetter, Markus" sort="Zweckstetter, Markus" uniqKey="Zweckstetter M" first="Markus" last="Zweckstetter">Markus Zweckstetter</name>
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<country name="Espagne"><noRegion><name sortKey="Requena, Jesus R" sort="Requena, Jesus R" uniqKey="Requena J" first="Jesús R." last="Requena">Jesús R. Requena</name>
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