Microelectrode recordings define the ventral posteromedial pallidotomy target
Identifieur interne : 000D49 ( PascalFrancis/Corpus ); précédent : 000D48; suivant : 000D50Microelectrode recordings define the ventral posteromedial pallidotomy target
Auteurs : A. M. Lozano ; W. D. Hutchison ; R. R. Tasker ; A. E. Lang ; F. Junn ; J. O. DostrovskySource :
- Stereotactic and functional neurosurgery [ 1011-6125 ] ; 1998.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
The benefits of stereotactic ventral posteromedial pallidotomy in the treatment of Parkinson's disease have been recently rediscovered. Optimal lesion location and lesion volume, however, have yet to be determined. Micro-electrode recording and microstimulation are carried out to determine an appropriate site for the placement of electrocoagulation lesions in the medial pallidum. The cellular activity of the globus pallidus is examined for characteristic firing patterns, mean firing rates, movement-evoked activity, and presence of tremor cells, laminae, and border zones. Microstimulation allows the identification of the adjacent optic tract by reports of visual sensation and of the internal capsule by sensorimotor responses. Lesions are centred at sites in the internal segment of the globus pallidus at least 3 mm from these structures, to avoid injury to them during pallidotomy.
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Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 99-0436209 INIST |
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ET : | Microelectrode recordings define the ventral posteromedial pallidotomy target |
AU : | LOZANO (A. M.); HUTCHISON (W. D.); TASKER (R. R.); LANG (A. E.); JUNN (F.); DOSTROVSKY (J. O.) |
AF : | Division of Neurosurgery, Department of Surgery, Toronto Hospital (Western Division)/Toronto/Canada (1 aut., 3 aut., 5 aut.); Department of Physiology and Faculty of Medicine, University of Toronto/Canada (2 aut., 6 aut.); Division of Neurology, Department of Medicine, Morton and Gloria Shulman Movement Disorders Centre, Toronto Hospital Neurological Centre and University of Toronto/Canada (4 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Stereotactic and functional neurosurgery; ISSN 1011-6125; Suisse; Da. 1998; Vol. 71; No. 4; Pp. 153-163; Bibl. 27 ref. |
LA : | Anglais |
EA : | The benefits of stereotactic ventral posteromedial pallidotomy in the treatment of Parkinson's disease have been recently rediscovered. Optimal lesion location and lesion volume, however, have yet to be determined. Micro-electrode recording and microstimulation are carried out to determine an appropriate site for the placement of electrocoagulation lesions in the medial pallidum. The cellular activity of the globus pallidus is examined for characteristic firing patterns, mean firing rates, movement-evoked activity, and presence of tremor cells, laminae, and border zones. Microstimulation allows the identification of the adjacent optic tract by reports of visual sensation and of the internal capsule by sensorimotor responses. Lesions are centred at sites in the internal segment of the globus pallidus at least 3 mm from these structures, to avoid injury to them during pallidotomy. |
CC : | 002B25J01 |
FD : | Parkinson maladie; Electrocoagulation; Pallidum; Ciblage; Microélectrode; Localisation; Traitement; Assistance technique; Adulte; Pallidotomie |
FG : | Homme; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Chirurgie stéréotaxique |
ED : | Parkinson disease; Electrocoagulation; Pallidum; Targeting; Microelectrode; Localization; Treatment; Technical assistance; Adult |
EG : | Human; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Stereotaxic surgery |
SD : | Parkinson enfermedad; Electrocoagulación; Pallidum; Blancado; Microeléctrodo; Localización; Tratamiento; Asistencia técnica; Adulto |
LO : | INIST-4980.354000086194550010 |
ID : | 99-0436209 |
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Pascal:99-0436209Le document en format XML
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<front><div type="abstract" xml:lang="en">The benefits of stereotactic ventral posteromedial pallidotomy in the treatment of Parkinson's disease have been recently rediscovered. Optimal lesion location and lesion volume, however, have yet to be determined. Micro-electrode recording and microstimulation are carried out to determine an appropriate site for the placement of electrocoagulation lesions in the medial pallidum. The cellular activity of the globus pallidus is examined for characteristic firing patterns, mean firing rates, movement-evoked activity, and presence of tremor cells, laminae, and border zones. Microstimulation allows the identification of the adjacent optic tract by reports of visual sensation and of the internal capsule by sensorimotor responses. Lesions are centred at sites in the internal segment of the globus pallidus at least 3 mm from these structures, to avoid injury to them during pallidotomy.</div>
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<ET>Microelectrode recordings define the ventral posteromedial pallidotomy target</ET>
<AU>LOZANO (A. M.); HUTCHISON (W. D.); TASKER (R. R.); LANG (A. E.); JUNN (F.); DOSTROVSKY (J. O.)</AU>
<AF>Division of Neurosurgery, Department of Surgery, Toronto Hospital (Western Division)/Toronto/Canada (1 aut., 3 aut., 5 aut.); Department of Physiology and Faculty of Medicine, University of Toronto/Canada (2 aut., 6 aut.); Division of Neurology, Department of Medicine, Morton and Gloria Shulman Movement Disorders Centre, Toronto Hospital Neurological Centre and University of Toronto/Canada (4 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Stereotactic and functional neurosurgery; ISSN 1011-6125; Suisse; Da. 1998; Vol. 71; No. 4; Pp. 153-163; Bibl. 27 ref.</SO>
<LA>Anglais</LA>
<EA>The benefits of stereotactic ventral posteromedial pallidotomy in the treatment of Parkinson's disease have been recently rediscovered. Optimal lesion location and lesion volume, however, have yet to be determined. Micro-electrode recording and microstimulation are carried out to determine an appropriate site for the placement of electrocoagulation lesions in the medial pallidum. The cellular activity of the globus pallidus is examined for characteristic firing patterns, mean firing rates, movement-evoked activity, and presence of tremor cells, laminae, and border zones. Microstimulation allows the identification of the adjacent optic tract by reports of visual sensation and of the internal capsule by sensorimotor responses. Lesions are centred at sites in the internal segment of the globus pallidus at least 3 mm from these structures, to avoid injury to them during pallidotomy.</EA>
<CC>002B25J01</CC>
<FD>Parkinson maladie; Electrocoagulation; Pallidum; Ciblage; Microélectrode; Localisation; Traitement; Assistance technique; Adulte; Pallidotomie</FD>
<FG>Homme; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Chirurgie stéréotaxique</FG>
<ED>Parkinson disease; Electrocoagulation; Pallidum; Targeting; Microelectrode; Localization; Treatment; Technical assistance; Adult</ED>
<EG>Human; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Stereotaxic surgery</EG>
<SD>Parkinson enfermedad; Electrocoagulación; Pallidum; Blancado; Microeléctrodo; Localización; Tratamiento; Asistencia técnica; Adulto</SD>
<LO>INIST-4980.354000086194550010</LO>
<ID>99-0436209</ID>
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