Genome-wide scan for Parkinson's disease: The genePD Study
Identifieur interne : 000C10 ( PascalFrancis/Corpus ); précédent : 000C09; suivant : 000C11Genome-wide scan for Parkinson's disease: The genePD Study
Auteurs : A. L. Destefano ; L. I. Golbe ; M. H. Mark ; A. M. Lazzarini ; N. E. Maher ; M. Saint-Hilaire ; R. G. Feldman ; M. Guttman ; R. L. Watts ; O. Suchowersky ; A. L. Lafontaine ; N. Labelle ; M. F. Lew ; C. H. Waters ; J. H. Growdon ; C. Singer ; L. J. Currie ; G. F. Wooten ; P. Vieregge ; P. P. Pramstaller ; C. Klein ; J. P. Hubble ; M. Stacy ; E. Montgomery ; M. E. Macdonald ; J. F. Gusella ; R. H. MyersSource :
- Neurology [ 0028-3878 ] ; 2001.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Article abstract-A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine β-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
pA |
|
---|
Format Inist (serveur)
NO : | PASCAL 02-0020721 INIST |
---|---|
ET : | Genome-wide scan for Parkinson's disease: The genePD Study |
AU : | DESTEFANO (A. L.); GOLBE (L. I.); MARK (M. H.); LAZZARINI (A. M.); MAHER (N. E.); SAINT-HILAIRE (M.); FELDMAN (R. G.); GUTTMAN (M.); WATTS (R. L.); SUCHOWERSKY (O.); LAFONTAINE (A. L.); LABELLE (N.); LEW (M. F.); WATERS (C. H.); GROWDON (J. H.); SINGER (C.); CURRIE (L. J.); WOOTEN (G. F.); VIEREGGE (P.); PRAMSTALLER (P. P.); KLEIN (C.); HUBBLE (J. P.); STACY (M.); MONTGOMERY (E.); MACDONALD (M. E.); GUSELLA (J. F.); MYERS (R. H.) |
AF : | Department of Neurology, Boston University Schools of Medicine and of Public Health/Boston, MA/Etats-Unis (1 aut., 5 aut., 6 aut., 7 aut., 27 aut.); Department of Epidemiology and Biostatistics, Boston University Schools of Medicine and of Public Health/Boston, MA/Etats-Unis (1 aut.); Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School/New Brunswick/Etats-Unis (2 aut., 3 aut., 4 aut.); Division of Neurology, Department of Medicine, University of Toronto,/Ontario/Etats-Unis (8 aut.); Department of Neurology, Emory University School of Medicine/Atlanta, GA/Etats-Unis (9 aut.); Departments of Clinical Neurosciences and Medical Genetics, University of Calgary/Alberta/Canada (10 aut., 11 aut., 12 aut.); Department of Neurology, University of Southern California/Los Angeles/Etats-Unis (13 aut., 14 aut.); Department of Neurology, Massachusetts General Hospital, Harvard Medical School/Boston, MA/Etats-Unis (15 aut., 25 aut., 26 aut.); Department of Neurology, University of Miami/FL/Etats-Unis (16 aut.); Department of Neurology, University of Virginia Health System/Charlottesville/Etats-Unis (17 aut., 18 aut.); Department of Neurology, Medical University of Lübeck/Allemagne (19 aut., 21 aut.); Department of Neurology, General Regional Hospital Bolzano/Italie (20 aut.); Department of Neurology, Ohio State University/Columbus/Etats-Unis (22 aut.); Department of Neurology, Barrow Clinic/Phoenix, AZ/Etats-Unis (23 aut.); Departments of Neurology and Neuroscience, Cleveland Clinic Foundation/OH/Etats-Unis (24 aut.) |
DT : | Publication en série; Courte communication, note brève; Niveau analytique |
SO : | Neurology; ISSN 0028-3878; Coden NEURAI; Etats-Unis; Da. 2001; Vol. 57; No. 6; Pp. 1124-1126; Bibl. 10 ref. |
LA : | Anglais |
EA : | Article abstract-A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine β-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others. |
CC : | 002B17G |
FD : | Parkinson maladie; Idiopathique; Liaison génétique; Chromosome C9; Etude familiale; Exploration; Homme |
FG : | Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Génétique |
ED : | Parkinson disease; Idiopathic; Linkage; Chromosome C9; Family study; Exploration; Human |
EG : | Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Genetics |
SD : | Parkinson enfermedad; Idiopático; Ligamiento genético; Cromosoma C9; Estudio familiar; Exploración; Hombre |
LO : | INIST-6345.354000099211080390 |
ID : | 02-0020721 |
Links to Exploration step
Pascal:02-0020721Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Genome-wide scan for Parkinson's disease: The genePD Study</title>
<author><name sortKey="Destefano, A L" sort="Destefano, A L" uniqKey="Destefano A" first="A. L." last="Destefano">A. L. Destefano</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>Department of Epidemiology and Biostatistics, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Golbe, L I" sort="Golbe, L I" uniqKey="Golbe L" first="L. I." last="Golbe">L. I. Golbe</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School</s1>
<s2>New Brunswick</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Mark, M H" sort="Mark, M H" uniqKey="Mark M" first="M. H." last="Mark">M. H. Mark</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School</s1>
<s2>New Brunswick</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lazzarini, A M" sort="Lazzarini, A M" uniqKey="Lazzarini A" first="A. M." last="Lazzarini">A. M. Lazzarini</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School</s1>
<s2>New Brunswick</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Maher, N E" sort="Maher, N E" uniqKey="Maher N" first="N. E." last="Maher">N. E. Maher</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Saint Hilaire, M" sort="Saint Hilaire, M" uniqKey="Saint Hilaire M" first="M." last="Saint-Hilaire">M. Saint-Hilaire</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Feldman, R G" sort="Feldman, R G" uniqKey="Feldman R" first="R. G." last="Feldman">R. G. Feldman</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Guttman, M" sort="Guttman, M" uniqKey="Guttman M" first="M." last="Guttman">M. Guttman</name>
<affiliation><inist:fA14 i1="04"><s1>Division of Neurology, Department of Medicine, University of Toronto,</s1>
<s2>Ontario</s2>
<s3>USA</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Watts, R L" sort="Watts, R L" uniqKey="Watts R" first="R. L." last="Watts">R. L. Watts</name>
<affiliation><inist:fA14 i1="05"><s1>Department of Neurology, Emory University School of Medicine</s1>
<s2>Atlanta, GA</s2>
<s3>USA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Suchowersky, O" sort="Suchowersky, O" uniqKey="Suchowersky O" first="O." last="Suchowersky">O. Suchowersky</name>
<affiliation><inist:fA14 i1="06"><s1>Departments of Clinical Neurosciences and Medical Genetics, University of Calgary</s1>
<s2>Alberta</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lafontaine, A L" sort="Lafontaine, A L" uniqKey="Lafontaine A" first="A. L." last="Lafontaine">A. L. Lafontaine</name>
<affiliation><inist:fA14 i1="06"><s1>Departments of Clinical Neurosciences and Medical Genetics, University of Calgary</s1>
<s2>Alberta</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Labelle, N" sort="Labelle, N" uniqKey="Labelle N" first="N." last="Labelle">N. Labelle</name>
<affiliation><inist:fA14 i1="06"><s1>Departments of Clinical Neurosciences and Medical Genetics, University of Calgary</s1>
<s2>Alberta</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lew, M F" sort="Lew, M F" uniqKey="Lew M" first="M. F." last="Lew">M. F. Lew</name>
<affiliation><inist:fA14 i1="07"><s1>Department of Neurology, University of Southern California</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Waters, C H" sort="Waters, C H" uniqKey="Waters C" first="C. H." last="Waters">C. H. Waters</name>
<affiliation><inist:fA14 i1="07"><s1>Department of Neurology, University of Southern California</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Growdon, J H" sort="Growdon, J H" uniqKey="Growdon J" first="J. H." last="Growdon">J. H. Growdon</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Massachusetts General Hospital, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
<sZ>25 aut.</sZ>
<sZ>26 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Singer, C" sort="Singer, C" uniqKey="Singer C" first="C." last="Singer">C. Singer</name>
<affiliation><inist:fA14 i1="09"><s1>Department of Neurology, University of Miami</s1>
<s2>FL</s2>
<s3>USA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Currie, L J" sort="Currie, L J" uniqKey="Currie L" first="L. J." last="Currie">L. J. Currie</name>
<affiliation><inist:fA14 i1="10"><s1>Department of Neurology, University of Virginia Health System</s1>
<s2>Charlottesville</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Wooten, G F" sort="Wooten, G F" uniqKey="Wooten G" first="G. F." last="Wooten">G. F. Wooten</name>
<affiliation><inist:fA14 i1="10"><s1>Department of Neurology, University of Virginia Health System</s1>
<s2>Charlottesville</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Vieregge, P" sort="Vieregge, P" uniqKey="Vieregge P" first="P." last="Vieregge">P. Vieregge</name>
<affiliation><inist:fA14 i1="11"><s1>Department of Neurology, Medical University of Lübeck</s1>
<s3>DEU</s3>
<sZ>19 aut.</sZ>
<sZ>21 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Pramstaller, P P" sort="Pramstaller, P P" uniqKey="Pramstaller P" first="P. P." last="Pramstaller">P. P. Pramstaller</name>
<affiliation><inist:fA14 i1="12"><s1>Department of Neurology, General Regional Hospital Bolzano</s1>
<s3>ITA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Klein, C" sort="Klein, C" uniqKey="Klein C" first="C." last="Klein">C. Klein</name>
<affiliation><inist:fA14 i1="11"><s1>Department of Neurology, Medical University of Lübeck</s1>
<s3>DEU</s3>
<sZ>19 aut.</sZ>
<sZ>21 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Hubble, J P" sort="Hubble, J P" uniqKey="Hubble J" first="J. P." last="Hubble">J. P. Hubble</name>
<affiliation><inist:fA14 i1="13"><s1>Department of Neurology, Ohio State University</s1>
<s2>Columbus</s2>
<s3>USA</s3>
<sZ>22 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Stacy, M" sort="Stacy, M" uniqKey="Stacy M" first="M." last="Stacy">M. Stacy</name>
<affiliation><inist:fA14 i1="14"><s1>Department of Neurology, Barrow Clinic</s1>
<s2>Phoenix, AZ</s2>
<s3>USA</s3>
<sZ>23 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Montgomery, E" sort="Montgomery, E" uniqKey="Montgomery E" first="E." last="Montgomery">E. Montgomery</name>
<affiliation><inist:fA14 i1="15"><s1>Departments of Neurology and Neuroscience, Cleveland Clinic Foundation</s1>
<s2>OH</s2>
<s3>USA</s3>
<sZ>24 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Macdonald, M E" sort="Macdonald, M E" uniqKey="Macdonald M" first="M. E." last="Macdonald">M. E. Macdonald</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Massachusetts General Hospital, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
<sZ>25 aut.</sZ>
<sZ>26 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Gusella, J F" sort="Gusella, J F" uniqKey="Gusella J" first="J. F." last="Gusella">J. F. Gusella</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Massachusetts General Hospital, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
<sZ>25 aut.</sZ>
<sZ>26 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Myers, R H" sort="Myers, R H" uniqKey="Myers R" first="R. H." last="Myers">R. H. Myers</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">02-0020721</idno>
<date when="2001">2001</date>
<idno type="stanalyst">PASCAL 02-0020721 INIST</idno>
<idno type="RBID">Pascal:02-0020721</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000C10</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Genome-wide scan for Parkinson's disease: The genePD Study</title>
<author><name sortKey="Destefano, A L" sort="Destefano, A L" uniqKey="Destefano A" first="A. L." last="Destefano">A. L. Destefano</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>Department of Epidemiology and Biostatistics, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Golbe, L I" sort="Golbe, L I" uniqKey="Golbe L" first="L. I." last="Golbe">L. I. Golbe</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School</s1>
<s2>New Brunswick</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Mark, M H" sort="Mark, M H" uniqKey="Mark M" first="M. H." last="Mark">M. H. Mark</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School</s1>
<s2>New Brunswick</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lazzarini, A M" sort="Lazzarini, A M" uniqKey="Lazzarini A" first="A. M." last="Lazzarini">A. M. Lazzarini</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School</s1>
<s2>New Brunswick</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Maher, N E" sort="Maher, N E" uniqKey="Maher N" first="N. E." last="Maher">N. E. Maher</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Saint Hilaire, M" sort="Saint Hilaire, M" uniqKey="Saint Hilaire M" first="M." last="Saint-Hilaire">M. Saint-Hilaire</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Feldman, R G" sort="Feldman, R G" uniqKey="Feldman R" first="R. G." last="Feldman">R. G. Feldman</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Guttman, M" sort="Guttman, M" uniqKey="Guttman M" first="M." last="Guttman">M. Guttman</name>
<affiliation><inist:fA14 i1="04"><s1>Division of Neurology, Department of Medicine, University of Toronto,</s1>
<s2>Ontario</s2>
<s3>USA</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Watts, R L" sort="Watts, R L" uniqKey="Watts R" first="R. L." last="Watts">R. L. Watts</name>
<affiliation><inist:fA14 i1="05"><s1>Department of Neurology, Emory University School of Medicine</s1>
<s2>Atlanta, GA</s2>
<s3>USA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Suchowersky, O" sort="Suchowersky, O" uniqKey="Suchowersky O" first="O." last="Suchowersky">O. Suchowersky</name>
<affiliation><inist:fA14 i1="06"><s1>Departments of Clinical Neurosciences and Medical Genetics, University of Calgary</s1>
<s2>Alberta</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lafontaine, A L" sort="Lafontaine, A L" uniqKey="Lafontaine A" first="A. L." last="Lafontaine">A. L. Lafontaine</name>
<affiliation><inist:fA14 i1="06"><s1>Departments of Clinical Neurosciences and Medical Genetics, University of Calgary</s1>
<s2>Alberta</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Labelle, N" sort="Labelle, N" uniqKey="Labelle N" first="N." last="Labelle">N. Labelle</name>
<affiliation><inist:fA14 i1="06"><s1>Departments of Clinical Neurosciences and Medical Genetics, University of Calgary</s1>
<s2>Alberta</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lew, M F" sort="Lew, M F" uniqKey="Lew M" first="M. F." last="Lew">M. F. Lew</name>
<affiliation><inist:fA14 i1="07"><s1>Department of Neurology, University of Southern California</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Waters, C H" sort="Waters, C H" uniqKey="Waters C" first="C. H." last="Waters">C. H. Waters</name>
<affiliation><inist:fA14 i1="07"><s1>Department of Neurology, University of Southern California</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Growdon, J H" sort="Growdon, J H" uniqKey="Growdon J" first="J. H." last="Growdon">J. H. Growdon</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Massachusetts General Hospital, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
<sZ>25 aut.</sZ>
<sZ>26 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Singer, C" sort="Singer, C" uniqKey="Singer C" first="C." last="Singer">C. Singer</name>
<affiliation><inist:fA14 i1="09"><s1>Department of Neurology, University of Miami</s1>
<s2>FL</s2>
<s3>USA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Currie, L J" sort="Currie, L J" uniqKey="Currie L" first="L. J." last="Currie">L. J. Currie</name>
<affiliation><inist:fA14 i1="10"><s1>Department of Neurology, University of Virginia Health System</s1>
<s2>Charlottesville</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Wooten, G F" sort="Wooten, G F" uniqKey="Wooten G" first="G. F." last="Wooten">G. F. Wooten</name>
<affiliation><inist:fA14 i1="10"><s1>Department of Neurology, University of Virginia Health System</s1>
<s2>Charlottesville</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Vieregge, P" sort="Vieregge, P" uniqKey="Vieregge P" first="P." last="Vieregge">P. Vieregge</name>
<affiliation><inist:fA14 i1="11"><s1>Department of Neurology, Medical University of Lübeck</s1>
<s3>DEU</s3>
<sZ>19 aut.</sZ>
<sZ>21 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Pramstaller, P P" sort="Pramstaller, P P" uniqKey="Pramstaller P" first="P. P." last="Pramstaller">P. P. Pramstaller</name>
<affiliation><inist:fA14 i1="12"><s1>Department of Neurology, General Regional Hospital Bolzano</s1>
<s3>ITA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Klein, C" sort="Klein, C" uniqKey="Klein C" first="C." last="Klein">C. Klein</name>
<affiliation><inist:fA14 i1="11"><s1>Department of Neurology, Medical University of Lübeck</s1>
<s3>DEU</s3>
<sZ>19 aut.</sZ>
<sZ>21 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Hubble, J P" sort="Hubble, J P" uniqKey="Hubble J" first="J. P." last="Hubble">J. P. Hubble</name>
<affiliation><inist:fA14 i1="13"><s1>Department of Neurology, Ohio State University</s1>
<s2>Columbus</s2>
<s3>USA</s3>
<sZ>22 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Stacy, M" sort="Stacy, M" uniqKey="Stacy M" first="M." last="Stacy">M. Stacy</name>
<affiliation><inist:fA14 i1="14"><s1>Department of Neurology, Barrow Clinic</s1>
<s2>Phoenix, AZ</s2>
<s3>USA</s3>
<sZ>23 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Montgomery, E" sort="Montgomery, E" uniqKey="Montgomery E" first="E." last="Montgomery">E. Montgomery</name>
<affiliation><inist:fA14 i1="15"><s1>Departments of Neurology and Neuroscience, Cleveland Clinic Foundation</s1>
<s2>OH</s2>
<s3>USA</s3>
<sZ>24 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Macdonald, M E" sort="Macdonald, M E" uniqKey="Macdonald M" first="M. E." last="Macdonald">M. E. Macdonald</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Massachusetts General Hospital, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
<sZ>25 aut.</sZ>
<sZ>26 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Gusella, J F" sort="Gusella, J F" uniqKey="Gusella J" first="J. F." last="Gusella">J. F. Gusella</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Massachusetts General Hospital, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
<sZ>25 aut.</sZ>
<sZ>26 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Myers, R H" sort="Myers, R H" uniqKey="Myers R" first="R. H." last="Myers">R. H. Myers</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Neurology</title>
<title level="j" type="abbreviated">Neurology</title>
<idno type="ISSN">0028-3878</idno>
<imprint><date when="2001">2001</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Neurology</title>
<title level="j" type="abbreviated">Neurology</title>
<idno type="ISSN">0028-3878</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chromosome C9</term>
<term>Exploration</term>
<term>Family study</term>
<term>Human</term>
<term>Idiopathic</term>
<term>Linkage</term>
<term>Parkinson disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term>
<term>Idiopathique</term>
<term>Liaison génétique</term>
<term>Chromosome C9</term>
<term>Etude familiale</term>
<term>Exploration</term>
<term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Article abstract-A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine β-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0028-3878</s0>
</fA01>
<fA02 i1="01"><s0>NEURAI</s0>
</fA02>
<fA03 i2="1"><s0>Neurology</s0>
</fA03>
<fA05><s2>57</s2>
</fA05>
<fA06><s2>6</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Genome-wide scan for Parkinson's disease: The genePD Study</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>DESTEFANO (A. L.)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>GOLBE (L. I.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>MARK (M. H.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>LAZZARINI (A. M.)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>MAHER (N. E.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>SAINT-HILAIRE (M.)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>FELDMAN (R. G.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>GUTTMAN (M.)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>WATTS (R. L.)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>SUCHOWERSKY (O.)</s1>
</fA11>
<fA11 i1="11" i2="1"><s1>LAFONTAINE (A. L.)</s1>
</fA11>
<fA11 i1="12" i2="1"><s1>LABELLE (N.)</s1>
</fA11>
<fA11 i1="13" i2="1"><s1>LEW (M. F.)</s1>
</fA11>
<fA11 i1="14" i2="1"><s1>WATERS (C. H.)</s1>
</fA11>
<fA11 i1="15" i2="1"><s1>GROWDON (J. H.)</s1>
</fA11>
<fA11 i1="16" i2="1"><s1>SINGER (C.)</s1>
</fA11>
<fA11 i1="17" i2="1"><s1>CURRIE (L. J.)</s1>
</fA11>
<fA11 i1="18" i2="1"><s1>WOOTEN (G. F.)</s1>
</fA11>
<fA11 i1="19" i2="1"><s1>VIEREGGE (P.)</s1>
</fA11>
<fA11 i1="20" i2="1"><s1>PRAMSTALLER (P. P.)</s1>
</fA11>
<fA11 i1="21" i2="1"><s1>KLEIN (C.)</s1>
</fA11>
<fA11 i1="22" i2="1"><s1>HUBBLE (J. P.)</s1>
</fA11>
<fA11 i1="23" i2="1"><s1>STACY (M.)</s1>
</fA11>
<fA11 i1="24" i2="1"><s1>MONTGOMERY (E.)</s1>
</fA11>
<fA11 i1="25" i2="1"><s1>MACDONALD (M. E.)</s1>
</fA11>
<fA11 i1="26" i2="1"><s1>GUSELLA (J. F.)</s1>
</fA11>
<fA11 i1="27" i2="1"><s1>MYERS (R. H.)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Neurology, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>27 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Department of Epidemiology and Biostatistics, Boston University Schools of Medicine and of Public Health</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School</s1>
<s2>New Brunswick</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Division of Neurology, Department of Medicine, University of Toronto,</s1>
<s2>Ontario</s2>
<s3>USA</s3>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Department of Neurology, Emory University School of Medicine</s1>
<s2>Atlanta, GA</s2>
<s3>USA</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Departments of Clinical Neurosciences and Medical Genetics, University of Calgary</s1>
<s2>Alberta</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</fA14>
<fA14 i1="07"><s1>Department of Neurology, University of Southern California</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
<sZ>14 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>Department of Neurology, Massachusetts General Hospital, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
<sZ>25 aut.</sZ>
<sZ>26 aut.</sZ>
</fA14>
<fA14 i1="09"><s1>Department of Neurology, University of Miami</s1>
<s2>FL</s2>
<s3>USA</s3>
<sZ>16 aut.</sZ>
</fA14>
<fA14 i1="10"><s1>Department of Neurology, University of Virginia Health System</s1>
<s2>Charlottesville</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</fA14>
<fA14 i1="11"><s1>Department of Neurology, Medical University of Lübeck</s1>
<s3>DEU</s3>
<sZ>19 aut.</sZ>
<sZ>21 aut.</sZ>
</fA14>
<fA14 i1="12"><s1>Department of Neurology, General Regional Hospital Bolzano</s1>
<s3>ITA</s3>
<sZ>20 aut.</sZ>
</fA14>
<fA14 i1="13"><s1>Department of Neurology, Ohio State University</s1>
<s2>Columbus</s2>
<s3>USA</s3>
<sZ>22 aut.</sZ>
</fA14>
<fA14 i1="14"><s1>Department of Neurology, Barrow Clinic</s1>
<s2>Phoenix, AZ</s2>
<s3>USA</s3>
<sZ>23 aut.</sZ>
</fA14>
<fA14 i1="15"><s1>Departments of Neurology and Neuroscience, Cleveland Clinic Foundation</s1>
<s2>OH</s2>
<s3>USA</s3>
<sZ>24 aut.</sZ>
</fA14>
<fA20><s1>1124-1126</s1>
</fA20>
<fA21><s1>2001</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>6345</s2>
<s5>354000099211080390</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2002 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>10 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>02-0020721</s0>
</fA47>
<fA60><s1>P</s1>
<s3>CC</s3>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Neurology</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Article abstract-A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine β-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17G</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Parkinson maladie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Parkinson enfermedad</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Idiopathique</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Idiopathic</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Idiopático</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Liaison génétique</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Linkage</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Ligamiento genético</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Chromosome C9</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Chromosome C9</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Cromosoma C9</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Etude familiale</s0>
<s5>16</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Family study</s0>
<s5>16</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Estudio familiar</s0>
<s5>16</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Exploration</s0>
<s5>17</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Exploration</s0>
<s5>17</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Exploración</s0>
<s5>17</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Homme</s0>
<s5>20</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Human</s0>
<s5>20</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Hombre</s0>
<s5>20</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Génétique</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Genetics</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Genética</s0>
<s5>45</s5>
</fC07>
<fN21><s1>007</s1>
</fN21>
</pA>
</standard>
<server><NO>PASCAL 02-0020721 INIST</NO>
<ET>Genome-wide scan for Parkinson's disease: The genePD Study</ET>
<AU>DESTEFANO (A. L.); GOLBE (L. I.); MARK (M. H.); LAZZARINI (A. M.); MAHER (N. E.); SAINT-HILAIRE (M.); FELDMAN (R. G.); GUTTMAN (M.); WATTS (R. L.); SUCHOWERSKY (O.); LAFONTAINE (A. L.); LABELLE (N.); LEW (M. F.); WATERS (C. H.); GROWDON (J. H.); SINGER (C.); CURRIE (L. J.); WOOTEN (G. F.); VIEREGGE (P.); PRAMSTALLER (P. P.); KLEIN (C.); HUBBLE (J. P.); STACY (M.); MONTGOMERY (E.); MACDONALD (M. E.); GUSELLA (J. F.); MYERS (R. H.)</AU>
<AF>Department of Neurology, Boston University Schools of Medicine and of Public Health/Boston, MA/Etats-Unis (1 aut., 5 aut., 6 aut., 7 aut., 27 aut.); Department of Epidemiology and Biostatistics, Boston University Schools of Medicine and of Public Health/Boston, MA/Etats-Unis (1 aut.); Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School/New Brunswick/Etats-Unis (2 aut., 3 aut., 4 aut.); Division of Neurology, Department of Medicine, University of Toronto,/Ontario/Etats-Unis (8 aut.); Department of Neurology, Emory University School of Medicine/Atlanta, GA/Etats-Unis (9 aut.); Departments of Clinical Neurosciences and Medical Genetics, University of Calgary/Alberta/Canada (10 aut., 11 aut., 12 aut.); Department of Neurology, University of Southern California/Los Angeles/Etats-Unis (13 aut., 14 aut.); Department of Neurology, Massachusetts General Hospital, Harvard Medical School/Boston, MA/Etats-Unis (15 aut., 25 aut., 26 aut.); Department of Neurology, University of Miami/FL/Etats-Unis (16 aut.); Department of Neurology, University of Virginia Health System/Charlottesville/Etats-Unis (17 aut., 18 aut.); Department of Neurology, Medical University of Lübeck/Allemagne (19 aut., 21 aut.); Department of Neurology, General Regional Hospital Bolzano/Italie (20 aut.); Department of Neurology, Ohio State University/Columbus/Etats-Unis (22 aut.); Department of Neurology, Barrow Clinic/Phoenix, AZ/Etats-Unis (23 aut.); Departments of Neurology and Neuroscience, Cleveland Clinic Foundation/OH/Etats-Unis (24 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Neurology; ISSN 0028-3878; Coden NEURAI; Etats-Unis; Da. 2001; Vol. 57; No. 6; Pp. 1124-1126; Bibl. 10 ref.</SO>
<LA>Anglais</LA>
<EA>Article abstract-A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine β-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others.</EA>
<CC>002B17G</CC>
<FD>Parkinson maladie; Idiopathique; Liaison génétique; Chromosome C9; Etude familiale; Exploration; Homme</FD>
<FG>Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Génétique</FG>
<ED>Parkinson disease; Idiopathic; Linkage; Chromosome C9; Family study; Exploration; Human</ED>
<EG>Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Genetics</EG>
<SD>Parkinson enfermedad; Idiopático; Ligamiento genético; Cromosoma C9; Estudio familiar; Exploración; Hombre</SD>
<LO>INIST-6345.354000099211080390</LO>
<ID>02-0020721</ID>
</server>
</inist>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C10 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000C10 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Canada |area= ParkinsonCanadaV1 |flux= PascalFrancis |étape= Corpus |type= RBID |clé= Pascal:02-0020721 |texte= Genome-wide scan for Parkinson's disease: The genePD Study }}
This area was generated with Dilib version V0.6.29. |