The role of dopamine in reward and pleasure behaviour : review of data from preclinical research
Identifieur interne : 000903 ( PascalFrancis/Corpus ); précédent : 000902; suivant : 000904The role of dopamine in reward and pleasure behaviour : review of data from preclinical research
Auteurs : R. A. Bressan ; J. A. CrippaSource :
- Acta psychiatrica scandinavica. Supplementum [ 0065-1591 ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Objective: The purpose of this article is to review some of the basic aspects of the dopaminergic system and its role in reward and pleasure behaviour. We also discuss the association between dopamine and unpleasant symptoms that are commonly found in neuropsychiatric disorders and may also be side-effects of neuroleptic drugs. Method: A computer-based search of the literature, augmented by extensive bibliography-guided article reviews, were used to find basic information on the dopamine and the reward systems, and symptoms such as dysphoria, anhedonia and depression. Results: Central dopaminergic neurotransmission is complex, having multiple actions at each level of the mesocorticolimbic reward pathway. The role of dopamine in the reward process was classically associated with the ability to experience pleasure; recent data suggest a more motivational role. Dysfunction of the dopamine transmission in the reward circuit is associated with symptoms such as anhedonia, apathy and dysphoria found in several neuropsychiatric disorders, including Parkinson's disease, depression, drug addiction, and neuroleptic-induced dysphoria. Conclusion: Viewing the dysfunctions of the reward pathways within a broader spectrum and exploring its complex relations with the dopaminergic transmission may help understand the pathophysiology of these neuropsychiatric disorders and lead to a rational development of novel treatments.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
|
|---|
Format Inist (serveur)
| NO : | PASCAL 05-0303487 INIST |
|---|---|
| ET : | The role of dopamine in reward and pleasure behaviour : review of data from preclinical research |
| AU : | BRESSAN (R. A.); CRIPPA (J. A.); AWAD (A. George); NABER (Dieter) |
| AF : | Interdisciplinary Lab of Neuroimaging and Cognition (LiNC), Department of Psychiatry, Federal University of Sao Paulo (UNIFESP)/Sao Paulo, SP/Brésil (1 aut.); Department of Neurology, Psychiatry and Psychological Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (USP-RP)/Sao Paulo, SP/Brésil (2 aut.); Department of Psychiatry and the Institute of Medical Science, University of Toronto/Toronto/Canada (1 aut.); Humber River Regional Hospital/Toronto/Canada (1 aut.); Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University of Hamburg/20246 Hamburg/Allemagne (2 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | Acta psychiatrica scandinavica. Supplementum; ISSN 0065-1591; Coden ASSUA6; Royaume-Uni; Da. 2005; Vol. 111; No. 427; Pp. 14-21; Bibl. 62 ref. |
| LA : | Anglais |
| EA : | Objective: The purpose of this article is to review some of the basic aspects of the dopaminergic system and its role in reward and pleasure behaviour. We also discuss the association between dopamine and unpleasant symptoms that are commonly found in neuropsychiatric disorders and may also be side-effects of neuroleptic drugs. Method: A computer-based search of the literature, augmented by extensive bibliography-guided article reviews, were used to find basic information on the dopamine and the reward systems, and symptoms such as dysphoria, anhedonia and depression. Results: Central dopaminergic neurotransmission is complex, having multiple actions at each level of the mesocorticolimbic reward pathway. The role of dopamine in the reward process was classically associated with the ability to experience pleasure; recent data suggest a more motivational role. Dysfunction of the dopamine transmission in the reward circuit is associated with symptoms such as anhedonia, apathy and dysphoria found in several neuropsychiatric disorders, including Parkinson's disease, depression, drug addiction, and neuroleptic-induced dysphoria. Conclusion: Viewing the dysfunctions of the reward pathways within a broader spectrum and exploring its complex relations with the dopaminergic transmission may help understand the pathophysiology of these neuropsychiatric disorders and lead to a rational development of novel treatments. |
| CC : | 002B18C07A; 002A26C05 |
| FD : | Dopamine; Récompense; Comportement; Article synthèse; Plaisir déplaisir; Etat dépressif; Homme; Dysphorie |
| FG : | Catécholamine; Neurotransmetteur; Trouble humeur |
| ED : | Dopamine; Reward; Behavior; Review; Pleasure unpleasure; Depression; Human; Dysphoria |
| EG : | Catecholamine; Neurotransmitter; Mood disorder |
| SD : | Dopamina; Recompensa; Conducta; Artículo síntesis; Placer disgusto; Estado depresivo; Hombre |
| LO : | INIST-3204B.354000125399700020 |
| ID : | 05-0303487 |
Links to Exploration step
Pascal:05-0303487Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">The role of dopamine in reward and pleasure behaviour : review of data from preclinical research</title><author><name sortKey="Bressan, R A" sort="Bressan, R A" uniqKey="Bressan R" first="R. A." last="Bressan">R. A. Bressan</name><affiliation><inist:fA14 i1="01"><s1>Interdisciplinary Lab of Neuroimaging and Cognition (LiNC), Department of Psychiatry, Federal University of Sao Paulo (UNIFESP)</s1><s2>Sao Paulo, SP</s2><s3>BRA</s3><sZ>1 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Crippa, J A" sort="Crippa, J A" uniqKey="Crippa J" first="J. A." last="Crippa">J. A. Crippa</name><affiliation><inist:fA14 i1="02"><s1>Department of Neurology, Psychiatry and Psychological Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (USP-RP)</s1><s2>Sao Paulo, SP</s2><s3>BRA</s3><sZ>2 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">05-0303487</idno><date when="2005">2005</date><idno type="stanalyst">PASCAL 05-0303487 INIST</idno><idno type="RBID">Pascal:05-0303487</idno><idno type="wicri:Area/PascalFrancis/Corpus">000903</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">The role of dopamine in reward and pleasure behaviour : review of data from preclinical research</title><author><name sortKey="Bressan, R A" sort="Bressan, R A" uniqKey="Bressan R" first="R. A." last="Bressan">R. A. Bressan</name><affiliation><inist:fA14 i1="01"><s1>Interdisciplinary Lab of Neuroimaging and Cognition (LiNC), Department of Psychiatry, Federal University of Sao Paulo (UNIFESP)</s1><s2>Sao Paulo, SP</s2><s3>BRA</s3><sZ>1 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Crippa, J A" sort="Crippa, J A" uniqKey="Crippa J" first="J. A." last="Crippa">J. A. Crippa</name><affiliation><inist:fA14 i1="02"><s1>Department of Neurology, Psychiatry and Psychological Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (USP-RP)</s1><s2>Sao Paulo, SP</s2><s3>BRA</s3><sZ>2 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">Acta psychiatrica scandinavica. Supplementum</title><title level="j" type="abbreviated">Acta psychiatr. scand., Suppl.</title><idno type="ISSN">0065-1591</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Acta psychiatrica scandinavica. Supplementum</title><title level="j" type="abbreviated">Acta psychiatr. scand., Suppl.</title><idno type="ISSN">0065-1591</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Behavior</term><term>Depression</term><term>Dopamine</term><term>Dysphoria</term><term>Human</term><term>Pleasure unpleasure</term><term>Review</term><term>Reward</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Dopamine</term><term>Récompense</term><term>Comportement</term><term>Article synthèse</term><term>Plaisir déplaisir</term><term>Etat dépressif</term><term>Homme</term><term>Dysphorie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: The purpose of this article is to review some of the basic aspects of the dopaminergic system and its role in reward and pleasure behaviour. We also discuss the association between dopamine and unpleasant symptoms that are commonly found in neuropsychiatric disorders and may also be side-effects of neuroleptic drugs. Method: A computer-based search of the literature, augmented by extensive bibliography-guided article reviews, were used to find basic information on the dopamine and the reward systems, and symptoms such as dysphoria, anhedonia and depression. Results: Central dopaminergic neurotransmission is complex, having multiple actions at each level of the mesocorticolimbic reward pathway. The role of dopamine in the reward process was classically associated with the ability to experience pleasure; recent data suggest a more motivational role. Dysfunction of the dopamine transmission in the reward circuit is associated with symptoms such as anhedonia, apathy and dysphoria found in several neuropsychiatric disorders, including Parkinson's disease, depression, drug addiction, and neuroleptic-induced dysphoria. Conclusion: Viewing the dysfunctions of the reward pathways within a broader spectrum and exploring its complex relations with the dopaminergic transmission may help understand the pathophysiology of these neuropsychiatric disorders and lead to a rational development of novel treatments.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0065-1591</s0></fA01><fA02 i1="01"><s0>ASSUA6</s0></fA02><fA03 i2="1"><s0>Acta psychiatr. scand., Suppl.</s0></fA03><fA05><s2>111</s2></fA05><fA06><s2>427</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>The role of dopamine in reward and pleasure behaviour : review of data from preclinical research</s1></fA08><fA09 i1="01" i2="1" l="ENG"><s1>Neuroleptic dysphoria and subjective experiences in schizophrenia - revisiting the concept 50 years later</s1></fA09><fA11 i1="01" i2="1"><s1>BRESSAN (R. A.)</s1></fA11><fA11 i1="02" i2="1"><s1>CRIPPA (J. A.)</s1></fA11><fA12 i1="01" i2="1"><s1>AWAD (A. George)</s1><s9>ed.</s9></fA12><fA12 i1="02" i2="1"><s1>NABER (Dieter)</s1><s9>ed.</s9></fA12><fA14 i1="01"><s1>Interdisciplinary Lab of Neuroimaging and Cognition (LiNC), Department of Psychiatry, Federal University of Sao Paulo (UNIFESP)</s1><s2>Sao Paulo, SP</s2><s3>BRA</s3><sZ>1 aut.</sZ></fA14><fA14 i1="02"><s1>Department of Neurology, Psychiatry and Psychological Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (USP-RP)</s1><s2>Sao Paulo, SP</s2><s3>BRA</s3><sZ>2 aut.</sZ></fA14><fA15 i1="01"><s1>Department of Psychiatry and the Institute of Medical Science, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ></fA15><fA15 i1="02"><s1>Humber River Regional Hospital</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ></fA15><fA15 i1="03"><s1>Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University of Hamburg</s1><s2>20246 Hamburg</s2><s3>DEU</s3><sZ>2 aut.</sZ></fA15><fA20><s1>14-21</s1></fA20><fA21><s1>2005</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>3204B</s2><s5>354000125399700020</s5></fA43><fA44><s0>0000</s0><s1>© 2005 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>62 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>05-0303487</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Acta psychiatrica scandinavica. Supplementum</s0></fA64><fA66 i1="01"><s0>GBR</s0></fA66><fC01 i1="01" l="ENG"><s0>Objective: The purpose of this article is to review some of the basic aspects of the dopaminergic system and its role in reward and pleasure behaviour. We also discuss the association between dopamine and unpleasant symptoms that are commonly found in neuropsychiatric disorders and may also be side-effects of neuroleptic drugs. Method: A computer-based search of the literature, augmented by extensive bibliography-guided article reviews, were used to find basic information on the dopamine and the reward systems, and symptoms such as dysphoria, anhedonia and depression. Results: Central dopaminergic neurotransmission is complex, having multiple actions at each level of the mesocorticolimbic reward pathway. The role of dopamine in the reward process was classically associated with the ability to experience pleasure; recent data suggest a more motivational role. Dysfunction of the dopamine transmission in the reward circuit is associated with symptoms such as anhedonia, apathy and dysphoria found in several neuropsychiatric disorders, including Parkinson's disease, depression, drug addiction, and neuroleptic-induced dysphoria. Conclusion: Viewing the dysfunctions of the reward pathways within a broader spectrum and exploring its complex relations with the dopaminergic transmission may help understand the pathophysiology of these neuropsychiatric disorders and lead to a rational development of novel treatments.</s0></fC01><fC02 i1="01" i2="X"><s0>002B18C07A</s0></fC02><fC02 i1="02" i2="X"><s0>002A26C05</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Dopamine</s0><s2>NK</s2><s2>FR</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Dopamine</s0><s2>NK</s2><s2>FR</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Dopamina</s0><s2>NK</s2><s2>FR</s2><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Récompense</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Reward</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Recompensa</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Comportement</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Behavior</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Conducta</s0><s5>03</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Article synthèse</s0><s5>04</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Review</s0><s5>04</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Artículo síntesis</s0><s5>04</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Plaisir déplaisir</s0><s5>05</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Pleasure unpleasure</s0><s5>05</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Placer disgusto</s0><s5>05</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Etat dépressif</s0><s5>06</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Depression</s0><s5>06</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Estado depresivo</s0><s5>06</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Homme</s0><s5>18</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Human</s0><s5>18</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Hombre</s0><s5>18</s5></fC03><fC03 i1="08" i2="X" l="FRE"><s0>Dysphorie</s0><s4>CD</s4><s5>96</s5></fC03><fC03 i1="08" i2="X" l="ENG"><s0>Dysphoria</s0><s4>CD</s4><s5>96</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Catécholamine</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Catecholamine</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Catecolamina</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Neurotransmetteur</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Neurotransmitter</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Neurotransmisor</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Trouble humeur</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Mood disorder</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Trastorno humor</s0><s5>39</s5></fC07><fN21><s1>213</s1></fN21></pA></standard><server><NO>PASCAL 05-0303487 INIST</NO><ET>The role of dopamine in reward and pleasure behaviour : review of data from preclinical research</ET><AU>BRESSAN (R. A.); CRIPPA (J. A.); AWAD (A. George); NABER (Dieter)</AU><AF>Interdisciplinary Lab of Neuroimaging and Cognition (LiNC), Department of Psychiatry, Federal University of Sao Paulo (UNIFESP)/Sao Paulo, SP/Brésil (1 aut.); Department of Neurology, Psychiatry and Psychological Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (USP-RP)/Sao Paulo, SP/Brésil (2 aut.); Department of Psychiatry and the Institute of Medical Science, University of Toronto/Toronto/Canada (1 aut.); Humber River Regional Hospital/Toronto/Canada (1 aut.); Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University of Hamburg/20246 Hamburg/Allemagne (2 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>Acta psychiatrica scandinavica. Supplementum; ISSN 0065-1591; Coden ASSUA6; Royaume-Uni; Da. 2005; Vol. 111; No. 427; Pp. 14-21; Bibl. 62 ref.</SO><LA>Anglais</LA><EA>Objective: The purpose of this article is to review some of the basic aspects of the dopaminergic system and its role in reward and pleasure behaviour. We also discuss the association between dopamine and unpleasant symptoms that are commonly found in neuropsychiatric disorders and may also be side-effects of neuroleptic drugs. Method: A computer-based search of the literature, augmented by extensive bibliography-guided article reviews, were used to find basic information on the dopamine and the reward systems, and symptoms such as dysphoria, anhedonia and depression. Results: Central dopaminergic neurotransmission is complex, having multiple actions at each level of the mesocorticolimbic reward pathway. The role of dopamine in the reward process was classically associated with the ability to experience pleasure; recent data suggest a more motivational role. Dysfunction of the dopamine transmission in the reward circuit is associated with symptoms such as anhedonia, apathy and dysphoria found in several neuropsychiatric disorders, including Parkinson's disease, depression, drug addiction, and neuroleptic-induced dysphoria. Conclusion: Viewing the dysfunctions of the reward pathways within a broader spectrum and exploring its complex relations with the dopaminergic transmission may help understand the pathophysiology of these neuropsychiatric disorders and lead to a rational development of novel treatments.</EA><CC>002B18C07A; 002A26C05</CC><FD>Dopamine; Récompense; Comportement; Article synthèse; Plaisir déplaisir; Etat dépressif; Homme; Dysphorie</FD><FG>Catécholamine; Neurotransmetteur; Trouble humeur</FG><ED>Dopamine; Reward; Behavior; Review; Pleasure unpleasure; Depression; Human; Dysphoria</ED><EG>Catecholamine; Neurotransmitter; Mood disorder</EG><SD>Dopamina; Recompensa; Conducta; Artículo síntesis; Placer disgusto; Estado depresivo; Hombre</SD><LO>INIST-3204B.354000125399700020</LO><ID>05-0303487</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000903 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000903 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:05-0303487
|texte= The role of dopamine in reward and pleasure behaviour : review of data from preclinical research
}}
| This area was generated with Dilib version V0.6.29. |  |