La maladie de Parkinson au Canada (serveur d'exploration)

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Intact encoding, impaired consolidation in procedural learning in Parkinson's disease

Identifieur interne : 000741 ( PascalFrancis/Corpus ); précédent : 000740; suivant : 000742

Intact encoding, impaired consolidation in procedural learning in Parkinson's disease

Auteurs : Henri Cohen ; Emmanuelle Pourcher

Source :

RBID : Pascal:07-0276680

Descripteurs français

English descriptors

Abstract

Idiopathic Parkinson's disease (IPD) patients and matched healthy participants were compared on a non-motor procedural task involving semantically related inverted word pairs, and 3 months later to determine the extent of skill consolidation. IPD patients were found to acquire new procedural skills necessary to read these inverted words, thus indicating that they are not impaired in all types of procedural learning. However, results on post-tests 3 months later, revealed significant group differences with IPD subjects showing little off-line learning relative to the controls. This suggests that a dopamine (DA)-deafferented neural system is not consolidated in the same way that a normally DA-innervated system is, and that impaired maintenance of procedures and routines may place IPD patients in a situation of constant relearning of embedded strategies in motor and non-motor domains.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A08 01  1  ENG  @1 Intact encoding, impaired consolidation in procedural learning in Parkinson's disease
A11 01  1    @1 COHEN (Henri)
A11 02  1    @1 POURCHER (Emmanuelle)
A14 01      @1 Cognitive Neuroscience Center, Université du Québec à Montréal and Laboratoire Psychologie et Neurosciences Cognitives, CNRS-Paris Descartes, Stn. Centre-Ville, PB 8888 @2 Montréal, QC, H3C 3P8 @3 CAN @Z 1 aut.
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C01 01    ENG  @0 Idiopathic Parkinson's disease (IPD) patients and matched healthy participants were compared on a non-motor procedural task involving semantically related inverted word pairs, and 3 months later to determine the extent of skill consolidation. IPD patients were found to acquire new procedural skills necessary to read these inverted words, thus indicating that they are not impaired in all types of procedural learning. However, results on post-tests 3 months later, revealed significant group differences with IPD subjects showing little off-line learning relative to the controls. This suggests that a dopamine (DA)-deafferented neural system is not consolidated in the same way that a normally DA-innervated system is, and that impaired maintenance of procedures and routines may place IPD patients in a situation of constant relearning of embedded strategies in motor and non-motor domains.
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Format Inist (serveur)

NO : PASCAL 07-0276680 INIST
ET : Intact encoding, impaired consolidation in procedural learning in Parkinson's disease
AU : COHEN (Henri); POURCHER (Emmanuelle)
AF : Cognitive Neuroscience Center, Université du Québec à Montréal and Laboratoire Psychologie et Neurosciences Cognitives, CNRS-Paris Descartes, Stn. Centre-Ville, PB 8888/Montréal, QC, H3C 3P8/Canada (1 aut.); Quebec Memory and Motor Skills Disorders Research Center, Clinique Sainte Anne/Québec/Canada (1 aut., 2 aut.)
DT : Publication en série; Niveau analytique
SO : Experimental brain research; ISSN 0014-4819; Coden EXBRAP; Allemagne; Da. 2007; Vol. 179; No. 4; Pp. 703-708; Bibl. 1/2 p.
LA : Anglais
EA : Idiopathic Parkinson's disease (IPD) patients and matched healthy participants were compared on a non-motor procedural task involving semantically related inverted word pairs, and 3 months later to determine the extent of skill consolidation. IPD patients were found to acquire new procedural skills necessary to read these inverted words, thus indicating that they are not impaired in all types of procedural learning. However, results on post-tests 3 months later, revealed significant group differences with IPD subjects showing little off-line learning relative to the controls. This suggests that a dopamine (DA)-deafferented neural system is not consolidated in the same way that a normally DA-innervated system is, and that impaired maintenance of procedures and routines may place IPD patients in a situation of constant relearning of embedded strategies in motor and non-motor domains.
CC : 002B17G; 002A26C04
FD : Apprentissage; Idiopathique; Stratégie; Parkinson maladie; Homme
FG : Processus acquisition; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Système nerveux pathologie
ED : Learning; Idiopathic; Strategy; Parkinson disease; Human
EG : Acquisition process; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases
SD : Aprendizaje; Idiopático; Estrategia; Parkinson enfermedad; Hombre
LO : INIST-12535.354000149651990160
ID : 07-0276680

Links to Exploration step

Pascal:07-0276680

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Data generation: Thu May 4 22:20:19 2017. Site generation: Fri Dec 23 23:17:26 2022