Diagnosis and management of Parkinson's disease dementia
Identifieur interne : 000626 ( PascalFrancis/Corpus ); précédent : 000625; suivant : 000627Diagnosis and management of Parkinson's disease dementia
Auteurs : W. Poewe ; S. Gauthier ; D. Aarsland ; J. B. Leverenz ; P. Barone ; D. Weintraub ; E. Tolosa ; B. DuboisSource :
- International journal of clinical practice : (Esher) [ 1368-5031 ] ; 2008.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Parkinson's disease (PD) has long been considered predominantly a motor disorder. However, its frequent association with dementia, which contributes significantly to the morbidity and mortality of the condition, is gaining increasing recognition. PD dementia (PDD) has a unique clinical profile and neuropathology, distinct from Alzheimer's disease (AD). Cholinergic deficits, a feature of both AD and PDD, underlie the rationale for cholinesterase inhibitor therapy in both conditions. In clinical practice, it is important that PDD should be recognised and appropriately treated. This review aims to outline the recently proposed clinical diagnostic criteria for PDD and to summarise the guidelines/recommendations published since 2006 on the use of cholinesterase inhibitors in the management of PDD. Although the cholinesterase inhibitor rivastigmine has recently been approved for the management of PDD, there remains a need for the development of novel therapies that can affect key mechanisms of the disease or prevent/delay patients with PD and mild cognitive impairment from progressing to PDD.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 08-0445025 INIST |
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ET : | Diagnosis and management of Parkinson's disease dementia |
AU : | POEWE (W.); GAUTHIER (S.); AARSLAND (D.); LEVERENZ (J. B.); BARONE (P.); WEINTRAUB (D.); TOLOSA (E.); DUBOIS (B.) |
AF : | Department of Neurology, Medical University Innsbruck/Innsbruck/Autriche (1 aut.); Alzheimer's Disease Research Unit, McGill Centre for Studies in Aging, Douglas Mental Health University Institute/Montréal, QC/Canada (2 aut.); Norweigen Centre for Movement Disorders, Stavenger University Hospital/Stavenger/Norvège (3 aut.); Institute of Clinical Medicine, University of Bergen/Bergen/Norvège (3 aut.); Mental Illness and Parkinson's Disease Research Education and Clinical Centers, VA-PSHCS, and Departments of Neurology and Psychiatry and Behavioral Sciences, University of Washington/Seattle, WA/Etats-Unis (4 aut.); Dipartimento di Scienze Neurologiche, Università Federico II di Napoli/Naples/Italie (5 aut.); Department of Psychiatry, University of Pennsylvania/Philadelphia, PA/Etats-Unis (6 aut.); Parkinson's Disease and Movement Disorders Unit, Institut Clinic de Neurociencies, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clinic de Barcelona, Institut d'lnvestigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona/Barcelona/Espagne (7 aut.); INSERM.UPMC UMRS 610, Federation of Neurology, Salpêtrière Hospital; University of Paris/Paris/France (8 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | International journal of clinical practice : (Esher); ISSN 1368-5031; Royaume-Uni; Da. 2008; Vol. 62; No. 10; Pp. 1581-1587; Bibl. 47 ref. |
LA : | Anglais |
EA : | Parkinson's disease (PD) has long been considered predominantly a motor disorder. However, its frequent association with dementia, which contributes significantly to the morbidity and mortality of the condition, is gaining increasing recognition. PD dementia (PDD) has a unique clinical profile and neuropathology, distinct from Alzheimer's disease (AD). Cholinergic deficits, a feature of both AD and PDD, underlie the rationale for cholinesterase inhibitor therapy in both conditions. In clinical practice, it is important that PDD should be recognised and appropriately treated. This review aims to outline the recently proposed clinical diagnostic criteria for PDD and to summarise the guidelines/recommendations published since 2006 on the use of cholinesterase inhibitors in the management of PDD. Although the cholinesterase inhibitor rivastigmine has recently been approved for the management of PDD, there remains a need for the development of novel therapies that can affect key mechanisms of the disease or prevent/delay patients with PD and mild cognitive impairment from progressing to PDD. |
CC : | 002B01; 002B17G |
FD : | Maladie de Parkinson; Diagnostic; Conduite à tenir; Démence; Médecine |
FG : | Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Pathologie du système nerveux |
ED : | Parkinson disease; Diagnosis; Clinical management; Dementia; Medicine |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases |
SD : | Parkinson enfermedad; Diagnóstico; Actitud médica; Demencia; Medicina |
LO : | INIST-15561.354000185233900160 |
ID : | 08-0445025 |
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Pascal:08-0445025Le document en format XML
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<front><div type="abstract" xml:lang="en">Parkinson's disease (PD) has long been considered predominantly a motor disorder. However, its frequent association with dementia, which contributes significantly to the morbidity and mortality of the condition, is gaining increasing recognition. PD dementia (PDD) has a unique clinical profile and neuropathology, distinct from Alzheimer's disease (AD). Cholinergic deficits, a feature of both AD and PDD, underlie the rationale for cholinesterase inhibitor therapy in both conditions. In clinical practice, it is important that PDD should be recognised and appropriately treated. This review aims to outline the recently proposed clinical diagnostic criteria for PDD and to summarise the guidelines/recommendations published since 2006 on the use of cholinesterase inhibitors in the management of PDD. Although the cholinesterase inhibitor rivastigmine has recently been approved for the management of PDD, there remains a need for the development of novel therapies that can affect key mechanisms of the disease or prevent/delay patients with PD and mild cognitive impairment from progressing to PDD.</div>
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</fC07>
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<s5>41</s5>
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<server><NO>PASCAL 08-0445025 INIST</NO>
<ET>Diagnosis and management of Parkinson's disease dementia</ET>
<AU>POEWE (W.); GAUTHIER (S.); AARSLAND (D.); LEVERENZ (J. B.); BARONE (P.); WEINTRAUB (D.); TOLOSA (E.); DUBOIS (B.)</AU>
<AF>Department of Neurology, Medical University Innsbruck/Innsbruck/Autriche (1 aut.); Alzheimer's Disease Research Unit, McGill Centre for Studies in Aging, Douglas Mental Health University Institute/Montréal, QC/Canada (2 aut.); Norweigen Centre for Movement Disorders, Stavenger University Hospital/Stavenger/Norvège (3 aut.); Institute of Clinical Medicine, University of Bergen/Bergen/Norvège (3 aut.); Mental Illness and Parkinson's Disease Research Education and Clinical Centers, VA-PSHCS, and Departments of Neurology and Psychiatry and Behavioral Sciences, University of Washington/Seattle, WA/Etats-Unis (4 aut.); Dipartimento di Scienze Neurologiche, Università Federico II di Napoli/Naples/Italie (5 aut.); Department of Psychiatry, University of Pennsylvania/Philadelphia, PA/Etats-Unis (6 aut.); Parkinson's Disease and Movement Disorders Unit, Institut Clinic de Neurociencies, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clinic de Barcelona, Institut d'lnvestigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona/Barcelona/Espagne (7 aut.); INSERM.UPMC UMRS 610, Federation of Neurology, Salpêtrière Hospital; University of Paris/Paris/France (8 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>International journal of clinical practice : (Esher); ISSN 1368-5031; Royaume-Uni; Da. 2008; Vol. 62; No. 10; Pp. 1581-1587; Bibl. 47 ref.</SO>
<LA>Anglais</LA>
<EA>Parkinson's disease (PD) has long been considered predominantly a motor disorder. However, its frequent association with dementia, which contributes significantly to the morbidity and mortality of the condition, is gaining increasing recognition. PD dementia (PDD) has a unique clinical profile and neuropathology, distinct from Alzheimer's disease (AD). Cholinergic deficits, a feature of both AD and PDD, underlie the rationale for cholinesterase inhibitor therapy in both conditions. In clinical practice, it is important that PDD should be recognised and appropriately treated. This review aims to outline the recently proposed clinical diagnostic criteria for PDD and to summarise the guidelines/recommendations published since 2006 on the use of cholinesterase inhibitors in the management of PDD. Although the cholinesterase inhibitor rivastigmine has recently been approved for the management of PDD, there remains a need for the development of novel therapies that can affect key mechanisms of the disease or prevent/delay patients with PD and mild cognitive impairment from progressing to PDD.</EA>
<CC>002B01; 002B17G</CC>
<FD>Maladie de Parkinson; Diagnostic; Conduite à tenir; Démence; Médecine</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Pathologie du système nerveux</FG>
<ED>Parkinson disease; Diagnosis; Clinical management; Dementia; Medicine</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases</EG>
<SD>Parkinson enfermedad; Diagnóstico; Actitud médica; Demencia; Medicina</SD>
<LO>INIST-15561.354000185233900160</LO>
<ID>08-0445025</ID>
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