ParkinsonCanadaV1, PascalFrancis, Corpus, bibRecord, 000312

Proprioceptive impairment and postural orientation control in Parkinson's disease

Identifieur interne : 000312 ( PascalFrancis/Corpus ); précédent : 000311; suivant : 000313

Proprioceptive impairment and postural orientation control in Parkinson's disease

Auteurs : Marianne Vaugoyeau ; Hussein Hakam ; Jean-Philippe Azulay

Source :

Human movement science [ 0167-9457 ] ; 2011.

RBID : Pascal:11-0280268

Descripteurs français

Pascal (Inist)
- Proprioception, Posture, Orientation, Homme, Maladie de Parkinson.

English descriptors

KwdEn :
- Human, Orientation, Parkinson disease, Posture, Proprioception.

Abstract

Impairment of postural control is a common consequence of Parkinson's disease (PD). Increasing evidences demonstrate that the pathophysiology of postural disorders in PD includes deficits in proprioceptive processing and integration. However, the nature of these deficits has not been thoroughly examined. We propose to establish a link between proprioceptive impairments and postural deficits in PD using two different experimental approaches manipulating proprioceptive information. In the first one, the subjects stood on a platform that tilted slowly with oscillatory angular movements in the frontal or sagittal planes. The amplitude and frequency of these movements were kept below the semicircular canal perception threshold. Subjects were asked to maintain vertical body posture with and without vision. The orientations of body segments were analyzed. In the second one, the postural control was tested using the tendon-vibration method, which is known to generate illusory movement sensations and postural reactions. Vibrations were applied to ankle muscles. The subject's whole-body motor responses were analyzed from center of pressure displacements. In the first experiment, the parkinsonian patients (PP) were unable to maintain the vertical trunk orientation without vision. Their performances with vision improved, without fully reaching the level of control subjects (CS). In the second experiment, the postural reactions of the PP were similar to those of the CS at the beginning of the perturbation and increased drastically at the end of the perturbation's period as compared to those of CS and could induce fall. These results will bring new concepts to the sensorimotor postural control, to the physiopathology of posture, equilibrium and falls in PD and to the role of basal ganglia pathways in proprioception integration. Nevertheless, in order to assess precisely the role played by sensorimotor integration deficits in postural impairments in PD, further studies establishing the links between clinical features and abnormalities are now required.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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C01	`01`		`ENG`	@0 Impairment of postural control is a common consequence of Parkinson's disease (PD). Increasing evidences demonstrate that the pathophysiology of postural disorders in PD includes deficits in proprioceptive processing and integration. However, the nature of these deficits has not been thoroughly examined. We propose to establish a link between proprioceptive impairments and postural deficits in PD using two different experimental approaches manipulating proprioceptive information. In the first one, the subjects stood on a platform that tilted slowly with oscillatory angular movements in the frontal or sagittal planes. The amplitude and frequency of these movements were kept below the semicircular canal perception threshold. Subjects were asked to maintain vertical body posture with and without vision. The orientations of body segments were analyzed. In the second one, the postural control was tested using the tendon-vibration method, which is known to generate illusory movement sensations and postural reactions. Vibrations were applied to ankle muscles. The subject's whole-body motor responses were analyzed from center of pressure displacements. In the first experiment, the parkinsonian patients (PP) were unable to maintain the vertical trunk orientation without vision. Their performances with vision improved, without fully reaching the level of control subjects (CS). In the second experiment, the postural reactions of the PP were similar to those of the CS at the beginning of the perturbation and increased drastically at the end of the perturbation's period as compared to those of CS and could induce fall. These results will bring new concepts to the sensorimotor postural control, to the physiopathology of posture, equilibrium and falls in PD and to the role of basal ganglia pathways in proprioception integration. Nevertheless, in order to assess precisely the role played by sensorimotor integration deficits in postural impairments in PD, further studies establishing the links between clinical features and abnormalities are now required.
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Format Inist (serveur)

NO :	PASCAL 11-0280268 INIST
ET :	Proprioceptive impairment and postural orientation control in Parkinson's disease
AU :	VAUGOYEAU (Marianne); HAKAM (Hussein); AZULAY (Jean-Philippe); SCHIEPPATI (Marco); SCHMID (Micaela)
AF :	CNRS - Universite Provence, Site Saint Charles, DPA-UMR 6149, Pôle 3C, Case B, 3 Place Victor Hugo/13331 Marseille/France (1 aut., 2 aut., 3 aut.); Department of Clinical Neurosciences, Movement Disorders Unit, hôpital de la Timone, 264, rue Saint-Pierre/13385 Marseille/France (2 aut., 3 aut.); Department of Experimental Medicine, Università degli Studi di Pavia, Via Forlanini 8/27100 Pavia/Italie (1 aut., 2 aut.); CSAM (Centro Studi Attività Motorie), Fondazione Salvatore Maugeri (IRCCS), Via Maugeri 10/27100 Pavia/Italie (1 aut., 2 aut.)
DT :	Publication en série; Congrès; Niveau analytique
SO :	Human movement science; ISSN 0167-9457; Coden HMSCDO; Pays-Bas; Da. 2011; Vol. 30; No. 2; Pp. 405-414; Bibl. 1 p.1/2
LA :	Anglais
EA :	Impairment of postural control is a common consequence of Parkinson's disease (PD). Increasing evidences demonstrate that the pathophysiology of postural disorders in PD includes deficits in proprioceptive processing and integration. However, the nature of these deficits has not been thoroughly examined. We propose to establish a link between proprioceptive impairments and postural deficits in PD using two different experimental approaches manipulating proprioceptive information. In the first one, the subjects stood on a platform that tilted slowly with oscillatory angular movements in the frontal or sagittal planes. The amplitude and frequency of these movements were kept below the semicircular canal perception threshold. Subjects were asked to maintain vertical body posture with and without vision. The orientations of body segments were analyzed. In the second one, the postural control was tested using the tendon-vibration method, which is known to generate illusory movement sensations and postural reactions. Vibrations were applied to ankle muscles. The subject's whole-body motor responses were analyzed from center of pressure displacements. In the first experiment, the parkinsonian patients (PP) were unable to maintain the vertical trunk orientation without vision. Their performances with vision improved, without fully reaching the level of control subjects (CS). In the second experiment, the postural reactions of the PP were similar to those of the CS at the beginning of the perturbation and increased drastically at the end of the perturbation's period as compared to those of CS and could induce fall. These results will bring new concepts to the sensorimotor postural control, to the physiopathology of posture, equilibrium and falls in PD and to the role of basal ganglia pathways in proprioception integration. Nevertheless, in order to assess precisely the role played by sensorimotor integration deficits in postural impairments in PD, further studies establishing the links between clinical features and abnormalities are now required.
CC :	002A24
FD :	Proprioception; Posture; Orientation; Homme; Maladie de Parkinson
FG :	Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Pathologie du système nerveux
ED :	Proprioception; Posture; Orientation; Human; Parkinson disease
EG :	Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases
SD :	Propiocepción; Postura; Orientación; Hombre; Parkinson enfermedad
LO :	INIST-19996.354000191571490190
ID :	11-0280268

Links to Exploration step

Pascal:11-0280268

Le document en format XML

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<front><div type="abstract" xml:lang="en">Impairment of postural control is a common consequence of Parkinson's disease (PD). Increasing evidences demonstrate that the pathophysiology of postural disorders in PD includes deficits in proprioceptive processing and integration. However, the nature of these deficits has not been thoroughly examined. We propose to establish a link between proprioceptive impairments and postural deficits in PD using two different experimental approaches manipulating proprioceptive information. In the first one, the subjects stood on a platform that tilted slowly with oscillatory angular movements in the frontal or sagittal planes. The amplitude and frequency of these movements were kept below the semicircular canal perception threshold. Subjects were asked to maintain vertical body posture with and without vision. The orientations of body segments were analyzed. In the second one, the postural control was tested using the tendon-vibration method, which is known to generate illusory movement sensations and postural reactions. Vibrations were applied to ankle muscles. The subject's whole-body motor responses were analyzed from center of pressure displacements. In the first experiment, the parkinsonian patients (PP) were unable to maintain the vertical trunk orientation without vision. Their performances with vision improved, without fully reaching the level of control subjects (CS). In the second experiment, the postural reactions of the PP were similar to those of the CS at the beginning of the perturbation and increased drastically at the end of the perturbation's period as compared to those of CS and could induce fall. These results will bring new concepts to the sensorimotor postural control, to the physiopathology of posture, equilibrium and falls in PD and to the role of basal ganglia pathways in proprioception integration. Nevertheless, in order to assess precisely the role played by sensorimotor integration deficits in postural impairments in PD, further studies establishing the links between clinical features and abnormalities are now required.</div>
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<s5>01</s5>
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<fC03 i1="01" i2="X" l="SPA"><s0>Propiocepción</s0>
<s5>01</s5>
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<s5>02</s5>
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<s5>02</s5>
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<s5>03</s5>
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<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Orientación</s0>
<s5>03</s5>
</fC03>
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<s5>04</s5>
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<s5>04</s5>
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<s5>09</s5>
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<s5>20</s5>
</fC07>
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</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>21</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>21</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>22</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>22</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>22</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Pathologie du   système nerveux central</s0>
<s5>23</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>23</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>23</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Pathologie du   système nerveux</s0>
<s5>24</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>24</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>24</s5>
</fC07>
<fN21><s1>185</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
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<pR><fA30 i1="01" i2="1" l="ENG"><s1>ISPGR Satellite PreConference</s1>
<s2>19</s2>
<s3>Pavia ITA</s3>
<s4>2009-06-09</s4>
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<server><NO>PASCAL 11-0280268 INIST</NO>
<ET>Proprioceptive impairment and postural orientation control in Parkinson's disease</ET>
<AU>VAUGOYEAU (Marianne); HAKAM (Hussein); AZULAY (Jean-Philippe); SCHIEPPATI (Marco); SCHMID (Micaela)</AU>
<AF>CNRS - Universite Provence, Site Saint Charles, DPA-UMR 6149, Pôle 3C, Case B, 3 Place Victor Hugo/13331 Marseille/France (1 aut., 2 aut., 3 aut.); Department of Clinical Neurosciences, Movement Disorders Unit, hôpital de la Timone, 264, rue Saint-Pierre/13385 Marseille/France (2 aut., 3 aut.); Department of Experimental Medicine, Università degli Studi di Pavia, Via Forlanini 8/27100 Pavia/Italie (1 aut., 2 aut.); CSAM (Centro Studi Attività Motorie), Fondazione Salvatore Maugeri (IRCCS), Via Maugeri 10/27100 Pavia/Italie (1 aut., 2 aut.)</AF>
<DT>Publication en série; Congrès; Niveau analytique</DT>
<SO>Human movement science; ISSN 0167-9457; Coden HMSCDO; Pays-Bas; Da. 2011; Vol. 30; No. 2; Pp. 405-414; Bibl. 1 p.1/2</SO>
<LA>Anglais</LA>
<EA>Impairment of postural control is a common consequence of Parkinson's disease (PD). Increasing evidences demonstrate that the pathophysiology of postural disorders in PD includes deficits in proprioceptive processing and integration. However, the nature of these deficits has not been thoroughly examined. We propose to establish a link between proprioceptive impairments and postural deficits in PD using two different experimental approaches manipulating proprioceptive information. In the first one, the subjects stood on a platform that tilted slowly with oscillatory angular movements in the frontal or sagittal planes. The amplitude and frequency of these movements were kept below the semicircular canal perception threshold. Subjects were asked to maintain vertical body posture with and without vision. The orientations of body segments were analyzed. In the second one, the postural control was tested using the tendon-vibration method, which is known to generate illusory movement sensations and postural reactions. Vibrations were applied to ankle muscles. The subject's whole-body motor responses were analyzed from center of pressure displacements. In the first experiment, the parkinsonian patients (PP) were unable to maintain the vertical trunk orientation without vision. Their performances with vision improved, without fully reaching the level of control subjects (CS). In the second experiment, the postural reactions of the PP were similar to those of the CS at the beginning of the perturbation and increased drastically at the end of the perturbation's period as compared to those of CS and could induce fall. These results will bring new concepts to the sensorimotor postural control, to the physiopathology of posture, equilibrium and falls in PD and to the role of basal ganglia pathways in proprioception integration. Nevertheless, in order to assess precisely the role played by sensorimotor integration deficits in postural impairments in PD, further studies establishing the links between clinical features and abnormalities are now required.</EA>
<CC>002A24</CC>
<FD>Proprioception; Posture; Orientation; Homme; Maladie de Parkinson</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du   système nerveux central; Pathologie du   système nerveux</FG>
<ED>Proprioception; Posture; Orientation; Human; Parkinson disease</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases</EG>
<SD>Propiocepción; Postura; Orientación; Hombre; Parkinson enfermedad</SD>
<LO>INIST-19996.354000191571490190</LO>
<ID>11-0280268</ID>
</server>
</inist>
</record>

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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

Proprioceptive impairment and postural orientation control in Parkinson's disease

Proprioceptive impairment and postural orientation control in Parkinson's disease

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