The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia
Identifieur interne : 000151 ( PascalFrancis/Corpus ); précédent : 000150; suivant : 000152The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia
Auteurs : Wei-Ju Lee ; Chia-Fen Tsai ; Serge Gauthier ; Shuu-Jiun Wang ; Jong-Ling FuhSource :
- International psychogeriatrics [ 1041-6102 ] ; 2012.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: Neuropsychiatric symptoms (NPS) are common in patients with dementia associated with Parkinson's disease (PDD). The relationship between cognition and NPS in PDD has not been well studied. Methods: Patients diagnosed with PDD were assessed for cognitive function and NPS. The instruments used were the Neuropsychiatric Inventory (NPI), Mini-Mental State Examination (MMSE), and semantic verbal fluency according to the recommendation of the Movement Disorder Society Task Force. Results: We evaluated 127 PDD patients (76 males/51 females; mean age 77 ± 6.3 years). Their mean MMSE score was 17 ±6.5 and the mean NPI score was 19 ± 20.4. The most prevalent NPI items were anxiety (57.5%), sleep problems (53.5%), and apathy (52.0%). Principal component factor analysis revealed that 12 items formed three factors, namely "mood and psychosis" (delusion, hallucination, agitation, depression, anxiety, apathy, and irritability), "vegetative" (sleep and appetite problems), and "frontal" (euphoria, disinhibition, and aberrant motor behavior). Symptoms of hallucination were significantly associated with MMSE score, even after controlling for the confounding variables. Conclusion: NPS are common and diverse among patients with PDD. Three specific subgroups of NPS were identified. Hallucination was significantly correlated with cognitive impairment, and could be a predictor of cognition in PDD patients.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
|
|---|
Format Inist (serveur)
| NO : | PASCAL 12-0453703 INIST |
|---|---|
| ET : | The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia |
| AU : | LEE (Wei-Ju); TSAI (Chia-Fen); GAUTHIER (Serge); WANG (Shuu-Jiun); FUH (Jong-Ling) |
| AF : | Department of Neurology, Taichung Veterans General Hospital/Taichung/Taïwan (1 aut.); Faculty of Medicine, National Yang-Ming University Schools of Medicine/Taipei/Taïwan (1 aut., 2 aut., 4 aut., 5 aut.); Institute of Clinical Medicine, National Yang-Ming University Schools of Medicine/Taipei/Taïwan (1 aut.); Department of Psychiatry, Taipei Veterans General Hospital/Taipei/Taïwan (2 aut.); Institute of Brain Science, National Yang-Ming University Schools of Medicine/Taipei/Taïwan (2 aut.); Department of Neurology and Neurosurgery, Psychiatry, Medicine, McGill University/Montreal, Quebec/Canada (3 aut.); Department of Neurology, Neurological Institute, Taipei Veterans General Hospital/Taipei/Taïwan (4 aut., 5 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | International psychogeriatrics; ISSN 1041-6102; Royaume-Uni; Da. 2012; Vol. 24; No. 12; Pp. 1980-1987; Bibl. 1 p.1/4 |
| LA : | Anglais |
| EA : | Background: Neuropsychiatric symptoms (NPS) are common in patients with dementia associated with Parkinson's disease (PDD). The relationship between cognition and NPS in PDD has not been well studied. Methods: Patients diagnosed with PDD were assessed for cognitive function and NPS. The instruments used were the Neuropsychiatric Inventory (NPI), Mini-Mental State Examination (MMSE), and semantic verbal fluency according to the recommendation of the Movement Disorder Society Task Force. Results: We evaluated 127 PDD patients (76 males/51 females; mean age 77 ± 6.3 years). Their mean MMSE score was 17 ±6.5 and the mean NPI score was 19 ± 20.4. The most prevalent NPI items were anxiety (57.5%), sleep problems (53.5%), and apathy (52.0%). Principal component factor analysis revealed that 12 items formed three factors, namely "mood and psychosis" (delusion, hallucination, agitation, depression, anxiety, apathy, and irritability), "vegetative" (sleep and appetite problems), and "frontal" (euphoria, disinhibition, and aberrant motor behavior). Symptoms of hallucination were significantly associated with MMSE score, even after controlling for the confounding variables. Conclusion: NPS are common and diverse among patients with PDD. Three specific subgroups of NPS were identified. Hallucination was significantly correlated with cognitive impairment, and could be a predictor of cognition in PDD patients. |
| CC : | 002B18E; 002B18C13; 002B17G; 002B17A01 |
| FD : | Trouble cognitif; Trouble psychiatrique; Neuropsychiatrie; Symptomatologie; Maladie de Parkinson; Démence; Cognition; Analyse factorielle; Homme; Personne âgée |
| FG : | Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Pathologie du système nerveux |
| ED : | Cognitive disorder; Mental disorder; Neuropsychiatry; Symptomatology; Parkinson disease; Dementia; Cognition; Factor analysis; Human; Elderly |
| EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases |
| SD : | Trastorno cognitivo; Trastorno psiquiátrico; Neurosiquiatría; Sintomatología; Parkinson enfermedad; Demencia; Cognición; Análisis factorial; Hombre; Anciano |
| LO : | INIST-26959.354000505424230110 |
| ID : | 12-0453703 |
Links to Exploration step
Pascal:12-0453703Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia</title><author><name sortKey="Lee, Wei Ju" sort="Lee, Wei Ju" uniqKey="Lee W" first="Wei-Ju" last="Lee">Wei-Ju Lee</name><affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Taichung Veterans General Hospital</s1><s2>Taichung</s2><s3>TWN</s3><sZ>1 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="03"><s1>Institute of Clinical Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Tsai, Chia Fen" sort="Tsai, Chia Fen" uniqKey="Tsai C" first="Chia-Fen" last="Tsai">Chia-Fen Tsai</name><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="04"><s1>Department of Psychiatry, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>2 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="05"><s1>Institute of Brain Science, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>2 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation><inist:fA14 i1="06"><s1>Department of Neurology and Neurosurgery, Psychiatry, Medicine, McGill University</s1><s2>Montreal, Quebec</s2><s3>CAN</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Wang, Shuu Jiun" sort="Wang, Shuu Jiun" uniqKey="Wang S" first="Shuu-Jiun" last="Wang">Shuu-Jiun Wang</name><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="07"><s1>Department of Neurology, Neurological Institute, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Fuh, Jong Ling" sort="Fuh, Jong Ling" uniqKey="Fuh J" first="Jong-Ling" last="Fuh">Jong-Ling Fuh</name><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="07"><s1>Department of Neurology, Neurological Institute, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0453703</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0453703 INIST</idno><idno type="RBID">Pascal:12-0453703</idno><idno type="wicri:Area/PascalFrancis/Corpus">000151</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia</title><author><name sortKey="Lee, Wei Ju" sort="Lee, Wei Ju" uniqKey="Lee W" first="Wei-Ju" last="Lee">Wei-Ju Lee</name><affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Taichung Veterans General Hospital</s1><s2>Taichung</s2><s3>TWN</s3><sZ>1 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="03"><s1>Institute of Clinical Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Tsai, Chia Fen" sort="Tsai, Chia Fen" uniqKey="Tsai C" first="Chia-Fen" last="Tsai">Chia-Fen Tsai</name><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="04"><s1>Department of Psychiatry, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>2 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="05"><s1>Institute of Brain Science, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>2 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation><inist:fA14 i1="06"><s1>Department of Neurology and Neurosurgery, Psychiatry, Medicine, McGill University</s1><s2>Montreal, Quebec</s2><s3>CAN</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Wang, Shuu Jiun" sort="Wang, Shuu Jiun" uniqKey="Wang S" first="Shuu-Jiun" last="Wang">Shuu-Jiun Wang</name><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="07"><s1>Department of Neurology, Neurological Institute, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Fuh, Jong Ling" sort="Fuh, Jong Ling" uniqKey="Fuh J" first="Jong-Ling" last="Fuh">Jong-Ling Fuh</name><affiliation><inist:fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation><affiliation><inist:fA14 i1="07"><s1>Department of Neurology, Neurological Institute, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">International psychogeriatrics</title><title level="j" type="abbreviated">Int. psychogeriatr.</title><idno type="ISSN">1041-6102</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">International psychogeriatrics</title><title level="j" type="abbreviated">Int. psychogeriatr.</title><idno type="ISSN">1041-6102</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cognition</term><term>Cognitive disorder</term><term>Dementia</term><term>Elderly</term><term>Factor analysis</term><term>Human</term><term>Mental disorder</term><term>Neuropsychiatry</term><term>Parkinson disease</term><term>Symptomatology</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Trouble cognitif</term><term>Trouble psychiatrique</term><term>Neuropsychiatrie</term><term>Symptomatologie</term><term>Maladie de Parkinson</term><term>Démence</term><term>Cognition</term><term>Analyse factorielle</term><term>Homme</term><term>Personne âgée</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Neuropsychiatric symptoms (NPS) are common in patients with dementia associated with Parkinson's disease (PDD). The relationship between cognition and NPS in PDD has not been well studied. Methods: Patients diagnosed with PDD were assessed for cognitive function and NPS. The instruments used were the Neuropsychiatric Inventory (NPI), Mini-Mental State Examination (MMSE), and semantic verbal fluency according to the recommendation of the Movement Disorder Society Task Force. Results: We evaluated 127 PDD patients (76 males/51 females; mean age 77 ± 6.3 years). Their mean MMSE score was 17 ±6.5 and the mean NPI score was 19 ± 20.4. The most prevalent NPI items were anxiety (57.5%), sleep problems (53.5%), and apathy (52.0%). Principal component factor analysis revealed that 12 items formed three factors, namely "mood and psychosis" (delusion, hallucination, agitation, depression, anxiety, apathy, and irritability), "vegetative" (sleep and appetite problems), and "frontal" (euphoria, disinhibition, and aberrant motor behavior). Symptoms of hallucination were significantly associated with MMSE score, even after controlling for the confounding variables. Conclusion: NPS are common and diverse among patients with PDD. Three specific subgroups of NPS were identified. Hallucination was significantly correlated with cognitive impairment, and could be a predictor of cognition in PDD patients.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>1041-6102</s0></fA01><fA03 i2="1"><s0>Int. psychogeriatr.</s0></fA03><fA05><s2>24</s2></fA05><fA06><s2>12</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia</s1></fA08><fA11 i1="01" i2="1"><s1>LEE (Wei-Ju)</s1></fA11><fA11 i1="02" i2="1"><s1>TSAI (Chia-Fen)</s1></fA11><fA11 i1="03" i2="1"><s1>GAUTHIER (Serge)</s1></fA11><fA11 i1="04" i2="1"><s1>WANG (Shuu-Jiun)</s1></fA11><fA11 i1="05" i2="1"><s1>FUH (Jong-Ling)</s1></fA11><fA14 i1="01"><s1>Department of Neurology, Taichung Veterans General Hospital</s1><s2>Taichung</s2><s3>TWN</s3><sZ>1 aut.</sZ></fA14><fA14 i1="02"><s1>Faculty of Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></fA14><fA14 i1="03"><s1>Institute of Clinical Medicine, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>1 aut.</sZ></fA14><fA14 i1="04"><s1>Department of Psychiatry, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>2 aut.</sZ></fA14><fA14 i1="05"><s1>Institute of Brain Science, National Yang-Ming University Schools of Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>2 aut.</sZ></fA14><fA14 i1="06"><s1>Department of Neurology and Neurosurgery, Psychiatry, Medicine, McGill University</s1><s2>Montreal, Quebec</s2><s3>CAN</s3><sZ>3 aut.</sZ></fA14><fA14 i1="07"><s1>Department of Neurology, Neurological Institute, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>4 aut.</sZ><sZ>5 aut.</sZ></fA14><fA20><s1>1980-1987</s1></fA20><fA21><s1>2012</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>26959</s2><s5>354000505424230110</s5></fA43><fA44><s0>0000</s0><s1>© 2012 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>1 p.1/4</s0></fA45><fA47 i1="01" i2="1"><s0>12-0453703</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>International psychogeriatrics</s0></fA64><fA66 i1="01"><s0>GBR</s0></fA66><fC01 i1="01" l="ENG"><s0>Background: Neuropsychiatric symptoms (NPS) are common in patients with dementia associated with Parkinson's disease (PDD). The relationship between cognition and NPS in PDD has not been well studied. Methods: Patients diagnosed with PDD were assessed for cognitive function and NPS. The instruments used were the Neuropsychiatric Inventory (NPI), Mini-Mental State Examination (MMSE), and semantic verbal fluency according to the recommendation of the Movement Disorder Society Task Force. Results: We evaluated 127 PDD patients (76 males/51 females; mean age 77 ± 6.3 years). Their mean MMSE score was 17 ±6.5 and the mean NPI score was 19 ± 20.4. The most prevalent NPI items were anxiety (57.5%), sleep problems (53.5%), and apathy (52.0%). Principal component factor analysis revealed that 12 items formed three factors, namely "mood and psychosis" (delusion, hallucination, agitation, depression, anxiety, apathy, and irritability), "vegetative" (sleep and appetite problems), and "frontal" (euphoria, disinhibition, and aberrant motor behavior). Symptoms of hallucination were significantly associated with MMSE score, even after controlling for the confounding variables. Conclusion: NPS are common and diverse among patients with PDD. Three specific subgroups of NPS were identified. Hallucination was significantly correlated with cognitive impairment, and could be a predictor of cognition in PDD patients.</s0></fC01><fC02 i1="01" i2="X"><s0>002B18E</s0></fC02><fC02 i1="02" i2="X"><s0>002B18C13</s0></fC02><fC02 i1="03" i2="X"><s0>002B17G</s0></fC02><fC02 i1="04" i2="X"><s0>002B17A01</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Trouble cognitif</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Cognitive disorder</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Trastorno cognitivo</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Trouble psychiatrique</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Mental disorder</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Trastorno psiquiátrico</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Neuropsychiatrie</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Neuropsychiatry</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Neurosiquiatría</s0><s5>03</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Symptomatologie</s0><s5>04</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Symptomatology</s0><s5>04</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Sintomatología</s0><s5>04</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Maladie de Parkinson</s0><s2>NM</s2><s5>05</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Parkinson disease</s0><s2>NM</s2><s5>05</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Parkinson enfermedad</s0><s2>NM</s2><s5>05</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Démence</s0><s5>06</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Dementia</s0><s5>06</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Demencia</s0><s5>06</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Cognition</s0><s5>07</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Cognition</s0><s5>07</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Cognición</s0><s5>07</s5></fC03><fC03 i1="08" i2="X" l="FRE"><s0>Analyse factorielle</s0><s5>08</s5></fC03><fC03 i1="08" i2="X" l="ENG"><s0>Factor analysis</s0><s5>08</s5></fC03><fC03 i1="08" i2="X" l="SPA"><s0>Análisis factorial</s0><s5>08</s5></fC03><fC03 i1="09" i2="X" l="FRE"><s0>Homme</s0><s5>18</s5></fC03><fC03 i1="09" i2="X" l="ENG"><s0>Human</s0><s5>18</s5></fC03><fC03 i1="09" i2="X" l="SPA"><s0>Hombre</s0><s5>18</s5></fC03><fC03 i1="10" i2="X" l="FRE"><s0>Personne âgée</s0><s5>19</s5></fC03><fC03 i1="10" i2="X" l="ENG"><s0>Elderly</s0><s5>19</s5></fC03><fC03 i1="10" i2="X" l="SPA"><s0>Anciano</s0><s5>19</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Syndrome extrapyramidal</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0><s5>39</s5></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Pathologie du système nerveux central</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0><s5>40</s5></fC07><fC07 i1="05" i2="X" l="FRE"><s0>Pathologie du système nerveux</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>41</s5></fC07><fN21><s1>353</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard><server><NO>PASCAL 12-0453703 INIST</NO><ET>The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia</ET><AU>LEE (Wei-Ju); TSAI (Chia-Fen); GAUTHIER (Serge); WANG (Shuu-Jiun); FUH (Jong-Ling)</AU><AF>Department of Neurology, Taichung Veterans General Hospital/Taichung/Taïwan (1 aut.); Faculty of Medicine, National Yang-Ming University Schools of Medicine/Taipei/Taïwan (1 aut., 2 aut., 4 aut., 5 aut.); Institute of Clinical Medicine, National Yang-Ming University Schools of Medicine/Taipei/Taïwan (1 aut.); Department of Psychiatry, Taipei Veterans General Hospital/Taipei/Taïwan (2 aut.); Institute of Brain Science, National Yang-Ming University Schools of Medicine/Taipei/Taïwan (2 aut.); Department of Neurology and Neurosurgery, Psychiatry, Medicine, McGill University/Montreal, Quebec/Canada (3 aut.); Department of Neurology, Neurological Institute, Taipei Veterans General Hospital/Taipei/Taïwan (4 aut., 5 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>International psychogeriatrics; ISSN 1041-6102; Royaume-Uni; Da. 2012; Vol. 24; No. 12; Pp. 1980-1987; Bibl. 1 p.1/4</SO><LA>Anglais</LA><EA>Background: Neuropsychiatric symptoms (NPS) are common in patients with dementia associated with Parkinson's disease (PDD). The relationship between cognition and NPS in PDD has not been well studied. Methods: Patients diagnosed with PDD were assessed for cognitive function and NPS. The instruments used were the Neuropsychiatric Inventory (NPI), Mini-Mental State Examination (MMSE), and semantic verbal fluency according to the recommendation of the Movement Disorder Society Task Force. Results: We evaluated 127 PDD patients (76 males/51 females; mean age 77 ± 6.3 years). Their mean MMSE score was 17 ±6.5 and the mean NPI score was 19 ± 20.4. The most prevalent NPI items were anxiety (57.5%), sleep problems (53.5%), and apathy (52.0%). Principal component factor analysis revealed that 12 items formed three factors, namely "mood and psychosis" (delusion, hallucination, agitation, depression, anxiety, apathy, and irritability), "vegetative" (sleep and appetite problems), and "frontal" (euphoria, disinhibition, and aberrant motor behavior). Symptoms of hallucination were significantly associated with MMSE score, even after controlling for the confounding variables. Conclusion: NPS are common and diverse among patients with PDD. Three specific subgroups of NPS were identified. Hallucination was significantly correlated with cognitive impairment, and could be a predictor of cognition in PDD patients.</EA><CC>002B18E; 002B18C13; 002B17G; 002B17A01</CC><FD>Trouble cognitif; Trouble psychiatrique; Neuropsychiatrie; Symptomatologie; Maladie de Parkinson; Démence; Cognition; Analyse factorielle; Homme; Personne âgée</FD><FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Pathologie du système nerveux</FG><ED>Cognitive disorder; Mental disorder; Neuropsychiatry; Symptomatology; Parkinson disease; Dementia; Cognition; Factor analysis; Human; Elderly</ED><EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases</EG><SD>Trastorno cognitivo; Trastorno psiquiátrico; Neurosiquiatría; Sintomatología; Parkinson enfermedad; Demencia; Cognición; Análisis factorial; Hombre; Anciano</SD><LO>INIST-26959.354000505424230110</LO><ID>12-0453703</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000151 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000151 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:12-0453703
|texte= The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia
}}
| This area was generated with Dilib version V0.6.29. |  |