ParkinsonCanadaV1, PascalFrancis, Corpus, bibRecord, 000049

Motor planning in Parkinson's disease patients experiencing freezing of gait: The influence of cognitive load when approaching obstacles

Identifieur interne : 000049 ( PascalFrancis/Corpus ); précédent : 000048; suivant : 000050

Motor planning in Parkinson's disease patients experiencing freezing of gait: The influence of cognitive load when approaching obstacles

Auteurs : Frederico Pieruccini-Faria ; Jeffery A. Jones ; Quincy J. Almeida

Source :

Brain and cognition : (Print) [ 0278-2626 ] ; 2014.

RBID : Francis:14-0158947

Descripteurs français

Pascal (Inist)
- Planification, Maladie de Parkinson, Allure, Charge mentale, Tâche concurrente, Cognition, Mouvement corporel, Homme.

English descriptors

KwdEn :
- Body movement, Cognition, Concurrent task, Gait, Human, Mental load, Parkinson disease, Planning.

Abstract

Freezing of gait (FOG) in Parkinson's disease (PD) is typically assumed to be a pure motor deficit, although it is important to consider how an abrupt loss of gait automaticity might be associated with an overloaded central resource capacity. If resource capacity limits are a factor underlying FOG, then obstacle crossing may be particularly sensitive to dual task effects in eliciting FOG. Participants performed a dual task (auditory digit monitoring) in order to increase cognitive load during obstacle crossing. Forty-two non-demented participants (14 PD patients with FOG, 13 PD who do not freeze, and 14 age-matched healthy control participants) were required to walk and step over a horizontal obstacle set at 15% of the participants' height. Kinematic data were split into two phases of their approach: early (farthest away from the obstacle), and late (just prior to the obstacle). Interestingly, step length variability and step time variability increased when PD patients with FOG performed the dual task, but only in the late phase prior to the obstacle (i.e. when closest to the obstacle). Additionally, immediately after crossing, freezers landed the lead foot abnormally close to the obstacle regardless of dual task condition, and also contacted the obstacle more frequently (planning errors). Strength of the dual task effect was associated with low general cognitive status, declined executive function, and inappropriate spatial planning, but only in the PD-FOG group. This study is the first to demonstrate that cognitive load differentially impacts planning of the final steps needed to avoid an obstacle in PD patients with freezing, but not non-freezers or healthy controls, suggesting specific neural networks associated with FOG behaviours.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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Format Inist (serveur)

NO :	FRANCIS 14-0158947 INIST
ET :	Motor planning in Parkinson's disease patients experiencing freezing of gait: The influence of cognitive load when approaching obstacles
AU :	PIERUCCINI-FARIA (Frederico); JONES (Jeffery A.); ALMEIDA (Quincy J.)
AF :	Sun Life Financial Movement Disorders Research & Rehabilitation Centre, Wilfrid Laurier University/Waterloo, Ontario N2L 3C5/Canada (1 aut., 2 aut., 3 aut.); Psychology Department, Wilfrid Laurier University/Waterloo, Ontario N2L 3C5/Canada (1 aut., 2 aut.); Laurier Centre for Cognitive Neuroscience, Wilfrid Laurier University/Waterloo, Ontario N2L 3C5/Canada (2 aut.)
DT :	Publication en série; Niveau analytique
SO :	Brain and cognition : (Print); ISSN 0278-2626; Coden BRCOEI; Pays-Bas; Da. 2014; Vol. 87; Pp. 76-85; Bibl. 3/4 p.
LA :	Anglais
EA :	Freezing of gait (FOG) in Parkinson's disease (PD) is typically assumed to be a pure motor deficit, although it is important to consider how an abrupt loss of gait automaticity might be associated with an overloaded central resource capacity. If resource capacity limits are a factor underlying FOG, then obstacle crossing may be particularly sensitive to dual task effects in eliciting FOG. Participants performed a dual task (auditory digit monitoring) in order to increase cognitive load during obstacle crossing. Forty-two non-demented participants (14 PD patients with FOG, 13 PD who do not freeze, and 14 age-matched healthy control participants) were required to walk and step over a horizontal obstacle set at 15% of the participants' height. Kinematic data were split into two phases of their approach: early (farthest away from the obstacle), and late (just prior to the obstacle). Interestingly, step length variability and step time variability increased when PD patients with FOG performed the dual task, but only in the late phase prior to the obstacle (i.e. when closest to the obstacle). Additionally, immediately after crossing, freezers landed the lead foot abnormally close to the obstacle regardless of dual task condition, and also contacted the obstacle more frequently (planning errors). Strength of the dual task effect was associated with low general cognitive status, declined executive function, and inappropriate spatial planning, but only in the PD-FOG group. This study is the first to demonstrate that cognitive load differentially impacts planning of the final steps needed to avoid an obstacle in PD patients with freezing, but not non-freezers or healthy controls, suggesting specific neural networks associated with FOG behaviours.
CC :	770D03M; 770B04D
FD :	Planification; Maladie de Parkinson; Allure; Charge mentale; Tâche concurrente; Cognition; Mouvement corporel; Homme
FG :	Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Pathologie du système nerveux; Motricité
ED :	Planning; Parkinson disease; Gait; Mental load; Concurrent task; Cognition; Body movement; Human
EG :	Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases; Motricity
SD :	Planificación; Parkinson enfermedad; Marcha; Carga mental; Tarea concurrente; Cognición; Movimiento corporal; Hombre
LO :	INIST-19677.354000502769070100
ID :	14-0158947

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Francis:14-0158947

Le document en format XML

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<front><div type="abstract" xml:lang="en">Freezing of gait (FOG) in Parkinson's disease (PD) is typically assumed to be a pure motor deficit, although it is important to consider how an abrupt loss of gait automaticity might be associated with an overloaded central resource capacity. If resource capacity limits are a factor underlying FOG, then obstacle crossing may be particularly sensitive to dual task effects in eliciting FOG. Participants performed a dual task (auditory digit monitoring) in order to increase cognitive load during obstacle crossing. Forty-two non-demented participants (14 PD patients with FOG, 13 PD who do not freeze, and 14 age-matched healthy control participants) were required to walk and step over a horizontal obstacle set at 15% of the participants' height. Kinematic data were split into two phases of their approach: early (farthest away from the obstacle), and late (just prior to the obstacle). Interestingly, step length variability and step time variability increased when PD patients with FOG performed the dual task, but only in the late phase prior to the obstacle (i.e. when closest to the obstacle). Additionally, immediately after crossing, freezers landed the lead foot abnormally close to the obstacle regardless of dual task condition, and also contacted the obstacle more frequently (planning errors). Strength of the dual task effect was associated with low general cognitive status, declined executive function, and inappropriate spatial planning, but only in the PD-FOG group. This study is the first to demonstrate that cognitive load differentially impacts planning of the final steps needed to avoid an obstacle in PD patients with freezing, but not non-freezers or healthy controls, suggesting specific neural networks associated with FOG behaviours.</div>
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</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Allure</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Gait</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Marcha</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Charge mentale</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Mental load</s0>
<s5>04</s5>
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<s5>04</s5>
</fC03>
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<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Concurrent task</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Tarea concurrente</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Cognition</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Cognition</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Cognición</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Mouvement corporel</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Body movement</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Movimiento corporal</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Homme</s0>
<s5>18</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Human</s0>
<s5>18</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Hombre</s0>
<s5>18</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Syndrome extrapyramidal</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Pathologie du   système nerveux central</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Pathologie du   système nerveux</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Motricité</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Motricity</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Motricidad</s0>
<s5>42</s5>
</fC07>
<fN21><s1>202</s1>
</fN21>
</pA>
</standard>
<server><NO>FRANCIS 14-0158947 INIST</NO>
<ET>Motor planning in Parkinson's disease patients experiencing freezing of gait: The influence of cognitive load when approaching obstacles</ET>
<AU>PIERUCCINI-FARIA (Frederico); JONES (Jeffery A.); ALMEIDA (Quincy J.)</AU>
<AF>Sun Life Financial Movement Disorders Research & Rehabilitation Centre, Wilfrid Laurier University/Waterloo, Ontario N2L 3C5/Canada (1 aut., 2 aut., 3 aut.); Psychology Department, Wilfrid Laurier University/Waterloo, Ontario N2L 3C5/Canada (1 aut., 2 aut.); Laurier Centre for Cognitive Neuroscience, Wilfrid Laurier University/Waterloo, Ontario N2L 3C5/Canada (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Brain and cognition : (Print); ISSN 0278-2626; Coden BRCOEI; Pays-Bas; Da. 2014; Vol. 87; Pp. 76-85; Bibl. 3/4 p.</SO>
<LA>Anglais</LA>
<EA>Freezing of gait (FOG) in Parkinson's disease (PD) is typically assumed to be a pure motor deficit, although it is important to consider how an abrupt loss of gait automaticity might be associated with an overloaded central resource capacity. If resource capacity limits are a factor underlying FOG, then obstacle crossing may be particularly sensitive to dual task effects in eliciting FOG. Participants performed a dual task (auditory digit monitoring) in order to increase cognitive load during obstacle crossing. Forty-two non-demented participants (14 PD patients with FOG, 13 PD who do not freeze, and 14 age-matched healthy control participants) were required to walk and step over a horizontal obstacle set at 15% of the participants' height. Kinematic data were split into two phases of their approach: early (farthest away from the obstacle), and late (just prior to the obstacle). Interestingly, step length variability and step time variability increased when PD patients with FOG performed the dual task, but only in the late phase prior to the obstacle (i.e. when closest to the obstacle). Additionally, immediately after crossing, freezers landed the lead foot abnormally close to the obstacle regardless of dual task condition, and also contacted the obstacle more frequently (planning errors). Strength of the dual task effect was associated with low general cognitive status, declined executive function, and inappropriate spatial planning, but only in the PD-FOG group. This study is the first to demonstrate that cognitive load differentially impacts planning of the final steps needed to avoid an obstacle in PD patients with freezing, but not non-freezers or healthy controls, suggesting specific neural networks associated with FOG behaviours.</EA>
<CC>770D03M; 770B04D</CC>
<FD>Planification; Maladie de Parkinson; Allure; Charge mentale; Tâche concurrente; Cognition; Mouvement corporel; Homme</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du   système nerveux central; Pathologie du   système nerveux; Motricité</FG>
<ED>Planning; Parkinson disease; Gait; Mental load; Concurrent task; Cognition; Body movement; Human</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Nervous system diseases; Motricity</EG>
<SD>Planificación; Parkinson enfermedad; Marcha; Carga mental; Tarea concurrente; Cognición; Movimiento corporal; Hombre</SD>
<LO>INIST-19677.354000502769070100</LO>
<ID>14-0158947</ID>
</server>
</inist>
</record>

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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

Motor planning in Parkinson's disease patients experiencing freezing of gait: The influence of cognitive load when approaching obstacles

Motor planning in Parkinson's disease patients experiencing freezing of gait: The influence of cognitive load when approaching obstacles

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