ParkinsonCanadaV1, PascalFrancis, Checkpoint, bibRecord, 000752

Anatomy and physiology of the basal Ganglia : Implications for deep brain stimulation for Parkinson's disease

Identifieur interne : 000752 ( PascalFrancis/Checkpoint ); précédent : 000751; suivant : 000753

Anatomy and physiology of the basal Ganglia : Implications for deep brain stimulation for Parkinson's disease

Auteurs : Brian H. Kopell [États-Unis] ; Ali R. Rezai [États-Unis] ; JIN WOO CHANG [Corée du Sud] ; Jerrold L. Vitek [États-Unis]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:06-0363505

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinson maladie, Anatomie, Physiologie, Noyau gris central, Stimulation cérébrale profonde.
Wicri :
- topic : Anatomie.

English descriptors

KwdEn :
- Anatomy, Basal ganglion, Deep brain stimulation, Nervous system diseases, Parkinson disease, Physiology.

Abstract

Central to surgical management of movement disorders is an understanding of the anatomy and physiology of the basal ganglia. The basal ganglia have been a target for neuromodulation surgery since Russell Meyers' pioneering works in the late 1930s. With the development of deep brain stimulation as the gold standard of surgical intervention for movement disorders, there has been a concomitant evolution in the understanding of the role the basal ganglia plays in the genesis of normal and abnormal motor behaviors. The fundamental concept of the cortico-striato-pallido-thalamocortical loop will be explored in the context of deep brain stimulation. The current targets for deep brain stimulation for Parkinson's disease, the subthalamic nucleus, the globus pallidus internus, and the ventral intermediate nucleus, will be discussed in the framework of the current physiological and anatomical models of Parkinson's disease (PD). Finally, the current understandings of the mechanisms underpinning the beneficial effects of deep brain stimulation for PD will be discussed.

Affiliations:

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Pascal:06-0363505

Le document en format XML

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<front><div type="abstract" xml:lang="en">Central to surgical management of movement disorders is an understanding of the anatomy and physiology of the basal ganglia. The basal ganglia have been a target for neuromodulation surgery since Russell Meyers' pioneering works in the late 1930s. With the development of deep brain stimulation as the gold standard of surgical intervention for movement disorders, there has been a concomitant evolution in the understanding of the role the basal ganglia plays in the genesis of normal and abnormal motor behaviors. The fundamental concept of the cortico-striato-pallido-thalamocortical loop will be explored in the context of deep brain stimulation. The current targets for deep brain stimulation for Parkinson's disease, the subthalamic nucleus, the globus pallidus internus, and the ventral intermediate nucleus, will be discussed in the framework of the current physiological and anatomical models of Parkinson's disease (PD). Finally, the current understandings of the mechanisms underpinning the beneficial effects of deep brain stimulation for PD will be discussed.</div>
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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

Anatomy and physiology of the basal Ganglia : Implications for deep brain stimulation for Parkinson's disease

Anatomy and physiology of the basal Ganglia : Implications for deep brain stimulation for Parkinson's disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri