ParkinsonCanadaV1, PascalFrancis, Checkpoint, bibRecord, 000122

Risk of Arrhythmia and Sudden Death in Patients With Asymptomatic Preexcitation: A Meta-Analysis

Identifieur interne : 000122 ( PascalFrancis/Checkpoint ); précédent : 000121; suivant : 000123

Risk of Arrhythmia and Sudden Death in Patients With Asymptomatic Preexcitation: A Meta-Analysis

Auteurs : Manoj N. Obeyesekere [Canada] ; Peter Leong-Sit [Canada] ; David Massel [Canada] ; Jaimie Manlucu [Canada] ; Simon Modi [Canada] ; Andrew D. Krahn [Canada] ; Allan C. Skanes [Canada] ; Raymond Yee [Canada] ; Lorne J. Gula [Canada] ; George J. Klein [Canada]

Source :

Circulation : (New York, N.Y.) [ 0009-7322 ] ; 2012.

RBID : Pascal:12-0229220

Descripteurs français

Pascal (Inist)
- Trouble du rythme cardiaque, Mort subite, Arrêt cardiocirculatoire, Syndrome de Wolff-Parkinson-White, Pathologie de l'appareil circulatoire, Facteur risque, Homme, Asymptomatique, Brutal, Tachycardie, Arrêt cardiorespiratoire.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Arrhythmia, Asymptomatic, Cardiocirculatory arrest, Cardiovascular disease, Human, Risk factor, Sudden, Sudden death, Tachycardia, Wolff-Parkinson-White syndrome.

Abstract

Background-The incidence of sudden cardiac death (SCD) and the management of this risk in patients with asymptomatic preexcitation remain controversial. The purpose of this meta-analysis was to define the incidence of SCD and supraventricular tachycardia in patients with asymptomatic Wolff-Parkinson-White ECG pattern. Methods and Results-We performed a systematic search of prospective, retrospective, randomized, or cohort English-language studies in EMBASE and Medline through February 2011. Studies reporting asymptomatic patients with preexcitation who did not undergo ablation were included. Twenty studies involving 1869 patients met our inclusion criteria. Participants were primarily male with a mean age ranging from 7 to 43 years. Ten SCDs were reported involving 11 722 person-years of follow-up. Seven studies originated from Italy and reported 9 SCDs. The risk of SCD is estimated at 1.25 per 1000 person-years (95% confidence interval [CI], 0.57-2.19). A total of 156 supraventricular tachycardias were reported involving 9884 person-years from 18 studies. The risk of supraventricular tachycardia was 16 (95% CI, 10-24) events per 1000 person-years of follow-up. Children had numerically higher SCD (1.93 [95% CI, 0.57-4.1] versus 0.86 [95% CI, 0.28-1.75]; P=0.07) and supraventricular tachycardia (20 [95% CI, 12-31] versus 14 [95% CI, 6-25]; P=0.38) event rates compared with adults. Conclusion-The low incidence of SCD and low risk of supraventricular tachycardia argue against routine invasive management in most asymptomatic patients with the Wolff-Parkinson-White ECG pattern.

Affiliations:

Canada

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Le document en format XML

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<series><title level="j" type="main">Circulation : (New York, N.Y.)</title>
<title level="j" type="abbreviated">Circulation : (N. Y. N.Y.)</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Arrhythmia</term>
<term>Asymptomatic</term>
<term>Cardiocirculatory arrest</term>
<term>Cardiovascular disease</term>
<term>Human</term>
<term>Risk factor</term>
<term>Sudden</term>
<term>Sudden death</term>
<term>Tachycardia</term>
<term>Wolff-Parkinson-White syndrome</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Trouble du rythme cardiaque</term>
<term>Mort subite</term>
<term>Arrêt cardiocirculatoire</term>
<term>Syndrome de Wolff-Parkinson-White</term>
<term>Pathologie de l'appareil circulatoire</term>
<term>Facteur risque</term>
<term>Homme</term>
<term>Asymptomatique</term>
<term>Brutal</term>
<term>Tachycardie</term>
<term>Arrêt cardiorespiratoire</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
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<front><div type="abstract" xml:lang="en">Background-The incidence of sudden cardiac death (SCD) and the management of this risk in patients with asymptomatic preexcitation remain controversial. The purpose of this meta-analysis was to define the incidence of SCD and supraventricular tachycardia in patients with asymptomatic Wolff-Parkinson-White ECG pattern. Methods and Results-We performed a systematic search of prospective, retrospective, randomized, or cohort English-language studies in EMBASE and Medline through February 2011. Studies reporting asymptomatic patients with preexcitation who did not undergo ablation were included. Twenty studies involving 1869 patients met our inclusion criteria. Participants were primarily male with a mean age ranging from 7 to 43 years. Ten SCDs were reported involving 11 722 person-years of follow-up. Seven studies originated from Italy and reported 9 SCDs. The risk of SCD is estimated at 1.25 per 1000 person-years (95% confidence interval [CI], 0.57-2.19). A total of 156 supraventricular tachycardias were reported involving 9884 person-years from 18 studies. The risk of supraventricular tachycardia was 16 (95% CI, 10-24) events per 1000 person-years of follow-up. Children had numerically higher SCD (1.93 [95% CI, 0.57-4.1] versus 0.86 [95% CI, 0.28-1.75]; P=0.07) and supraventricular tachycardia (20 [95% CI, 12-31] versus 14 [95% CI, 6-25]; P=0.38) event rates compared with adults. Conclusion-The low incidence of SCD and low risk of supraventricular tachycardia argue against routine invasive management in most asymptomatic patients with the Wolff-Parkinson-White ECG pattern.</div>
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<fA11 i1="02" i2="1"><s1>LEONG-SIT (Peter)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>MASSEL (David)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>MANLUCU (Jaimie)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>MODI (Simon)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>KRAHN (Andrew D.)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>SKANES (Allan C.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>YEE (Raymond)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>GULA (Lorne J.)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>KLEIN (George J.)</s1>
</fA11>
<fA14 i1="01"><s1>University of Western Ontario, Division of Cardiology</s1>
<s2>London, Ontario</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</fA14>
<fA20><s1>2308-2315</s1>
</fA20>
<fA21><s1>2012</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>5907</s2>
<s5>354000507909230060</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2012 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>45 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>12-0229220</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Circulation : (New York, N.Y.)</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Background-The incidence of sudden cardiac death (SCD) and the management of this risk in patients with asymptomatic preexcitation remain controversial. The purpose of this meta-analysis was to define the incidence of SCD and supraventricular tachycardia in patients with asymptomatic Wolff-Parkinson-White ECG pattern. Methods and Results-We performed a systematic search of prospective, retrospective, randomized, or cohort English-language studies in EMBASE and Medline through February 2011. Studies reporting asymptomatic patients with preexcitation who did not undergo ablation were included. Twenty studies involving 1869 patients met our inclusion criteria. Participants were primarily male with a mean age ranging from 7 to 43 years. Ten SCDs were reported involving 11 722 person-years of follow-up. Seven studies originated from Italy and reported 9 SCDs. The risk of SCD is estimated at 1.25 per 1000 person-years (95% confidence interval [CI], 0.57-2.19). A total of 156 supraventricular tachycardias were reported involving 9884 person-years from 18 studies. The risk of supraventricular tachycardia was 16 (95% CI, 10-24) events per 1000 person-years of follow-up. Children had numerically higher SCD (1.93 [95% CI, 0.57-4.1] versus 0.86 [95% CI, 0.28-1.75]; P=0.07) and supraventricular tachycardia (20 [95% CI, 12-31] versus 14 [95% CI, 6-25]; P=0.38) event rates compared with adults. Conclusion-The low incidence of SCD and low risk of supraventricular tachycardia argue against routine invasive management in most asymptomatic patients with the Wolff-Parkinson-White ECG pattern.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B12B03</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B12A03</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Trouble du rythme cardiaque</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Arrhythmia</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Arritmia</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Mort subite</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Sudden death</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Muerte súbita</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Arrêt cardiocirculatoire</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Cardiocirculatory arrest</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Paro cardiocirculatorio</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Syndrome de Wolff-Parkinson-White</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Wolff-Parkinson-White syndrome</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Wolff-Parkinson-White síndrome</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Pathologie de l'appareil circulatoire</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Cardiovascular disease</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Aparato circulatorio patología</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Facteur risque</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Risk factor</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Factor riesgo</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Homme</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Human</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Hombre</s0>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Asymptomatique</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Asymptomatic</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Asintomático</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Brutal</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Sudden</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Súbito</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Tachycardie</s0>
<s5>13</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Tachycardia</s0>
<s5>13</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Taquicardia</s0>
<s5>13</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Arrêt cardiorespiratoire</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Cardiopathie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Heart disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Cardiopatía</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Trouble de la conduction</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Conduction disorder</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Trastorno conducción</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Trouble de l'excitabilité</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Excitability disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Trastorno excitabilidad</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Syndrome de préexcitation ventriculaire</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Ventricular preexcitation syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Preexcitación ventricular síndrome</s0>
<s5>40</s5>
</fC07>
<fN21><s1>177</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations><list><country><li>Canada</li>
</country>
</list>
<tree><country name="Canada"><noRegion><name sortKey="Obeyesekere, Manoj N" sort="Obeyesekere, Manoj N" uniqKey="Obeyesekere M" first="Manoj N." last="Obeyesekere">Manoj N. Obeyesekere</name>
</noRegion>
<name sortKey="Gula, Lorne J" sort="Gula, Lorne J" uniqKey="Gula L" first="Lorne J." last="Gula">Lorne J. Gula</name>
<name sortKey="Klein, George J" sort="Klein, George J" uniqKey="Klein G" first="George J." last="Klein">George J. Klein</name>
<name sortKey="Krahn, Andrew D" sort="Krahn, Andrew D" uniqKey="Krahn A" first="Andrew D." last="Krahn">Andrew D. Krahn</name>
<name sortKey="Leong Sit, Peter" sort="Leong Sit, Peter" uniqKey="Leong Sit P" first="Peter" last="Leong-Sit">Peter Leong-Sit</name>
<name sortKey="Manlucu, Jaimie" sort="Manlucu, Jaimie" uniqKey="Manlucu J" first="Jaimie" last="Manlucu">Jaimie Manlucu</name>
<name sortKey="Massel, David" sort="Massel, David" uniqKey="Massel D" first="David" last="Massel">David Massel</name>
<name sortKey="Modi, Simon" sort="Modi, Simon" uniqKey="Modi S" first="Simon" last="Modi">Simon Modi</name>
<name sortKey="Skanes, Allan C" sort="Skanes, Allan C" uniqKey="Skanes A" first="Allan C." last="Skanes">Allan C. Skanes</name>
<name sortKey="Yee, Raymond" sort="Yee, Raymond" uniqKey="Yee R" first="Raymond" last="Yee">Raymond Yee</name>
</country>
</tree>
</affiliations>
</record>

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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

Risk of Arrhythmia and Sudden Death in Patients With Asymptomatic Preexcitation: A Meta-Analysis

Risk of Arrhythmia and Sudden Death in Patients With Asymptomatic Preexcitation: A Meta-Analysis

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