Neural overlap between resting state and self-relevant activity in human subcallosal cingulate cortex - Single unit recording in an intracranial study
Identifieur interne : 000009 ( PascalFrancis/Checkpoint ); précédent : 000008; suivant : 000010Neural overlap between resting state and self-relevant activity in human subcallosal cingulate cortex - Single unit recording in an intracranial study
Auteurs : Nir Lipsman [Canada] ; Takashi Nakao [Japon] ; Noriaki Kanayama [Japon] ; Joachim K. Krauss [Allemagne] ; Adam Anderson [Canada] ; Peter Giacobbe [Canada] ; Clement Hamani [Canada] ; William D. Hutchison [Canada] ; Jonathan O. Dostrousky [Canada] ; Thilo Womelsdorf [Canada] ; Andres M. Lozano [Canada] ; Georg Northoff [Canada, Taïwan, République populaire de Chine]Source :
- Cortex : (Testo stampato) [ 0010-9452 ] ; 2014.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
High activity of the default mode network (DMN) has been proposed to be central in processing self-relevant events. Thus far, this hypothesis of DMN function has not been tested directly using neurophysiological techniques. To test for the link between frontal midline DMN activity and self-relevant processing we measured neuronal activity (single-neurons' firing rates) in human subcallosal cingulate cortex (SCC) in the course of Deep Brain Stimulation surgery. We find that firing rates in SCC did not change during the presentation of specifically self-relevant stimuli when compared to the preceding pre-stimulus resting state level. In contrast, we observed significant changes in firing rates during other names in SCC. Such rest-self overlap seems to be specific for SCC since increase in firing rates in response to self-relevant stimuli were observed in another region, the subthalamic nucleus, in a group of Parkinson patients receiving deep brain stimulation surgery. These results suggest specific relationship between resting state and self-related activity, rest-self overlap, in specifically SCC as core region of the default-mode network.
Affiliations:
- Allemagne, Canada, Japon, République populaire de Chine, Taïwan
- Basse-Saxe, Ontario, Zhejiang
- Hangzhou, Hanovre, Toronto
- Université de Toronto
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000006
- to stream PascalFrancis, to step Corpus: 000046
- to stream PascalFrancis, to step Curation: 000C12
Links to Exploration step
Pascal:14-0278836Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Neural overlap between resting state and self-relevant activity in human subcallosal cingulate cortex - Single unit recording in an intracranial study</title><author><name sortKey="Lipsman, Nir" sort="Lipsman, Nir" uniqKey="Lipsman N" first="Nir" last="Lipsman">Nir Lipsman</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Division of Neurosurgery, Toronto Western Hospital, University of Toronto</s1><s3>CAN</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Nakao, Takashi" sort="Nakao, Takashi" uniqKey="Nakao T" first="Takashi" last="Nakao">Takashi Nakao</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Institute of Biomedical & Health Sciences, Hiroshima University</s1><s3>JPN</s3><sZ>2 aut.</sZ></inist:fA14><country>Japon</country><wicri:noRegion>Institute of Biomedical & Health Sciences, Hiroshima University</wicri:noRegion></affiliation></author><author><name sortKey="Kanayama, Noriaki" sort="Kanayama, Noriaki" uniqKey="Kanayama N" first="Noriaki" last="Kanayama">Noriaki Kanayama</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Graduate School of Arts and Sciences, Department of General Systems Studies, University of Tokyo</s1><s3>JPN</s3><sZ>3 aut.</sZ></inist:fA14><country>Japon</country><wicri:noRegion>Graduate School of Arts and Sciences, Department of General Systems Studies, University of Tokyo</wicri:noRegion></affiliation></author><author><name sortKey="Krauss, Joachim K" sort="Krauss, Joachim K" uniqKey="Krauss J" first="Joachim K." last="Krauss">Joachim K. Krauss</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurosurgery, Medizinische Hochschule</s1><s2>Hannover</s2><s3>DEU</s3><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Anderson, Adam" sort="Anderson, Adam" uniqKey="Anderson A" first="Adam" last="Anderson">Adam Anderson</name><affiliation wicri:level="4"><inist:fA14 i1="05"><s1>Department of Psychology, University of Toronto</s1><s3>CAN</s3><sZ>5 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Giacobbe, Peter" sort="Giacobbe, Peter" uniqKey="Giacobbe P" first="Peter" last="Giacobbe">Peter Giacobbe</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Division of Psychiatry, Toronto General Hospital, University of Toronto</s1><s3>CAN</s3><sZ>6 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Hamani, Clement" sort="Hamani, Clement" uniqKey="Hamani C" first="Clement" last="Hamani">Clement Hamani</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Division of Neurosurgery, Toronto Western Hospital, University of Toronto</s1><s3>CAN</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D." last="Hutchison">William D. Hutchison</name><affiliation wicri:level="4"><inist:fA14 i1="07"><s1>Department of Physiology, University of Toronto</s1><s3>CAN</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Dostrousky, Jonathan O" sort="Dostrousky, Jonathan O" uniqKey="Dostrousky J" first="Jonathan O." last="Dostrousky">Jonathan O. Dostrousky</name><affiliation wicri:level="4"><inist:fA14 i1="07"><s1>Department of Physiology, University of Toronto</s1><s3>CAN</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Womelsdorf, Thilo" sort="Womelsdorf, Thilo" uniqKey="Womelsdorf T" first="Thilo" last="Womelsdorf">Thilo Womelsdorf</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Biology, York University</s1><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Department of Biology, York University</wicri:noRegion></affiliation></author><author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M." last="Lozano">Andres M. Lozano</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Division of Neurosurgery, Toronto Western Hospital, University of Toronto</s1><s3>CAN</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Northoff, Georg" sort="Northoff, Georg" uniqKey="Northoff G" first="Georg" last="Northoff">Georg Northoff</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Psychiatry, University of Ottawa Institute of Mental Health Research</s1><s3>CAN</s3><sZ>12 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Department of Psychiatry, University of Ottawa Institute of Mental Health Research</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Taipei Medical University, Graduate Institute of Humanities in Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>12 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>Taipei</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Taipei Medical University-Shuang Ho Hospital, Brain and Consciousness Research Center</s1><s2>New Taipei City</s2><s3>TWN</s3><sZ>12 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>New Taipei City</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Centre for Cognition and Brain Disorders (CBBD), Normal University Hangzhou</s1><s2>Hangzhou</s2><s3>CHN</s3><sZ>12 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">14-0278836</idno><date when="2014">2014</date><idno type="stanalyst">PASCAL 14-0278836 INIST</idno><idno type="RBID">Pascal:14-0278836</idno><idno type="wicri:Area/PascalFrancis/Corpus">000006</idno><idno type="stanalyst">FRANCIS 14-0278836 INIST</idno><idno type="wicri:Area/PascalFrancis/Corpus">000046</idno><idno type="wicri:Area/PascalFrancis/Curation">000C12</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000009</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000009</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Neural overlap between resting state and self-relevant activity in human subcallosal cingulate cortex - Single unit recording in an intracranial study</title><author><name sortKey="Lipsman, Nir" sort="Lipsman, Nir" uniqKey="Lipsman N" first="Nir" last="Lipsman">Nir Lipsman</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Division of Neurosurgery, Toronto Western Hospital, University of Toronto</s1><s3>CAN</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Nakao, Takashi" sort="Nakao, Takashi" uniqKey="Nakao T" first="Takashi" last="Nakao">Takashi Nakao</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Institute of Biomedical & Health Sciences, Hiroshima University</s1><s3>JPN</s3><sZ>2 aut.</sZ></inist:fA14><country>Japon</country><wicri:noRegion>Institute of Biomedical & Health Sciences, Hiroshima University</wicri:noRegion></affiliation></author><author><name sortKey="Kanayama, Noriaki" sort="Kanayama, Noriaki" uniqKey="Kanayama N" first="Noriaki" last="Kanayama">Noriaki Kanayama</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Graduate School of Arts and Sciences, Department of General Systems Studies, University of Tokyo</s1><s3>JPN</s3><sZ>3 aut.</sZ></inist:fA14><country>Japon</country><wicri:noRegion>Graduate School of Arts and Sciences, Department of General Systems Studies, University of Tokyo</wicri:noRegion></affiliation></author><author><name sortKey="Krauss, Joachim K" sort="Krauss, Joachim K" uniqKey="Krauss J" first="Joachim K." last="Krauss">Joachim K. Krauss</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurosurgery, Medizinische Hochschule</s1><s2>Hannover</s2><s3>DEU</s3><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Anderson, Adam" sort="Anderson, Adam" uniqKey="Anderson A" first="Adam" last="Anderson">Adam Anderson</name><affiliation wicri:level="4"><inist:fA14 i1="05"><s1>Department of Psychology, University of Toronto</s1><s3>CAN</s3><sZ>5 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Giacobbe, Peter" sort="Giacobbe, Peter" uniqKey="Giacobbe P" first="Peter" last="Giacobbe">Peter Giacobbe</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Division of Psychiatry, Toronto General Hospital, University of Toronto</s1><s3>CAN</s3><sZ>6 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Hamani, Clement" sort="Hamani, Clement" uniqKey="Hamani C" first="Clement" last="Hamani">Clement Hamani</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Division of Neurosurgery, Toronto Western Hospital, University of Toronto</s1><s3>CAN</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D." last="Hutchison">William D. Hutchison</name><affiliation wicri:level="4"><inist:fA14 i1="07"><s1>Department of Physiology, University of Toronto</s1><s3>CAN</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Dostrousky, Jonathan O" sort="Dostrousky, Jonathan O" uniqKey="Dostrousky J" first="Jonathan O." last="Dostrousky">Jonathan O. Dostrousky</name><affiliation wicri:level="4"><inist:fA14 i1="07"><s1>Department of Physiology, University of Toronto</s1><s3>CAN</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Womelsdorf, Thilo" sort="Womelsdorf, Thilo" uniqKey="Womelsdorf T" first="Thilo" last="Womelsdorf">Thilo Womelsdorf</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Biology, York University</s1><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Department of Biology, York University</wicri:noRegion></affiliation></author><author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M." last="Lozano">Andres M. Lozano</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Division of Neurosurgery, Toronto Western Hospital, University of Toronto</s1><s3>CAN</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Northoff, Georg" sort="Northoff, Georg" uniqKey="Northoff G" first="Georg" last="Northoff">Georg Northoff</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Psychiatry, University of Ottawa Institute of Mental Health Research</s1><s3>CAN</s3><sZ>12 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Department of Psychiatry, University of Ottawa Institute of Mental Health Research</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Taipei Medical University, Graduate Institute of Humanities in Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>12 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>Taipei</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Taipei Medical University-Shuang Ho Hospital, Brain and Consciousness Research Center</s1><s2>New Taipei City</s2><s3>TWN</s3><sZ>12 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>New Taipei City</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Centre for Cognition and Brain Disorders (CBBD), Normal University Hangzhou</s1><s2>Hangzhou</s2><s3>CHN</s3><sZ>12 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Cortex : (Testo stampato)</title><title level="j" type="abbreviated">Cortex : (Testo stamp.)</title><idno type="ISSN">0010-9452</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Cortex : (Testo stampato)</title><title level="j" type="abbreviated">Cortex : (Testo stamp.)</title><idno type="ISSN">0010-9452</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cingulate cortex</term><term>Deep brain stimulation</term><term>Default mode network</term><term>Human</term><term>Intracerebral</term><term>Rest</term><term>Self</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Repos</term><term>Soi</term><term>Intracérébral</term><term>Cortex cingulaire</term><term>Homme</term><term>Réseau du mode par défaut</term><term>Stimulation cérébrale profonde</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">High activity of the default mode network (DMN) has been proposed to be central in processing self-relevant events. Thus far, this hypothesis of DMN function has not been tested directly using neurophysiological techniques. To test for the link between frontal midline DMN activity and self-relevant processing we measured neuronal activity (single-neurons' firing rates) in human subcallosal cingulate cortex (SCC) in the course of Deep Brain Stimulation surgery. We find that firing rates in SCC did not change during the presentation of specifically self-relevant stimuli when compared to the preceding pre-stimulus resting state level. In contrast, we observed significant changes in firing rates during other names in SCC. Such rest-self overlap seems to be specific for SCC since increase in firing rates in response to self-relevant stimuli were observed in another region, the subthalamic nucleus, in a group of Parkinson patients receiving deep brain stimulation surgery. These results suggest specific relationship between resting state and self-related activity, rest-self overlap, in specifically SCC as core region of the default-mode network.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0010-9452</s0></fA01><fA02 i1="01"><s0>CRTXAZ</s0></fA02><fA03 i2="1"><s0>Cortex : (Testo stamp.)</s0></fA03><fA05><s2>60</s2></fA05><fA08 i1="01" i2="1" l="ENG"><s1>Neural overlap between resting state and self-relevant activity in human subcallosal cingulate cortex - Single unit recording in an intracranial study</s1></fA08><fA09 i1="01" i2="1" l="ENG"><s1>WHAT DOES HUMAN INTRACEREBRAL RECORDING TELL US ABOUT EMOTIONS?</s1></fA09><fA11 i1="01" i2="1"><s1>LIPSMAN (Nir)</s1></fA11><fA11 i1="02" i2="1"><s1>NAKAO (Takashi)</s1></fA11><fA11 i1="03" i2="1"><s1>KANAYAMA (Noriaki)</s1></fA11><fA11 i1="04" i2="1"><s1>KRAUSS (Joachim K.)</s1></fA11><fA11 i1="05" i2="1"><s1>ANDERSON (Adam)</s1></fA11><fA11 i1="06" i2="1"><s1>GIACOBBE (Peter)</s1></fA11><fA11 i1="07" i2="1"><s1>HAMANI (Clement)</s1></fA11><fA11 i1="08" i2="1"><s1>HUTCHISON (William D.)</s1></fA11><fA11 i1="09" i2="1"><s1>DOSTROUSKY (Jonathan O.)</s1></fA11><fA11 i1="10" i2="1"><s1>WOMELSDORF (Thilo)</s1></fA11><fA11 i1="11" i2="1"><s1>LOZANO (Andres M.)</s1></fA11><fA11 i1="12" i2="1"><s1>NORTHOFF (Georg)</s1></fA11><fA12 i1="01" i2="1"><s1>PERON (Julie)</s1><s9>ed.</s9></fA12><fA12 i1="02" i2="1"><s1>GRANDJEAN (Didier)</s1><s9>ed.</s9></fA12><fA14 i1="01"><s1>Division of Neurosurgery, Toronto Western Hospital, University of Toronto</s1><s3>CAN</s3><sZ>1 aut.</sZ><sZ>7 aut.</sZ><sZ>11 aut.</sZ></fA14><fA14 i1="02"><s1>Institute of Biomedical & Health Sciences, Hiroshima University</s1><s3>JPN</s3><sZ>2 aut.</sZ></fA14><fA14 i1="03"><s1>Graduate School of Arts and Sciences, Department of General Systems Studies, University of Tokyo</s1><s3>JPN</s3><sZ>3 aut.</sZ></fA14><fA14 i1="04"><s1>Department of Neurosurgery, Medizinische Hochschule</s1><s2>Hannover</s2><s3>DEU</s3><sZ>4 aut.</sZ></fA14><fA14 i1="05"><s1>Department of Psychology, University of Toronto</s1><s3>CAN</s3><sZ>5 aut.</sZ></fA14><fA14 i1="06"><s1>Division of Psychiatry, Toronto General Hospital, University of Toronto</s1><s3>CAN</s3><sZ>6 aut.</sZ></fA14><fA14 i1="07"><s1>Department of Physiology, University of Toronto</s1><s3>CAN</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ></fA14><fA14 i1="08"><s1>Department of Biology, York University</s1><s3>CAN</s3><sZ>10 aut.</sZ></fA14><fA14 i1="09"><s1>Department of Psychiatry, University of Ottawa Institute of Mental Health Research</s1><s3>CAN</s3><sZ>12 aut.</sZ></fA14><fA14 i1="10"><s1>Taipei Medical University, Graduate Institute of Humanities in Medicine</s1><s2>Taipei</s2><s3>TWN</s3><sZ>12 aut.</sZ></fA14><fA14 i1="11"><s1>Taipei Medical University-Shuang Ho Hospital, Brain and Consciousness Research Center</s1><s2>New Taipei City</s2><s3>TWN</s3><sZ>12 aut.</sZ></fA14><fA14 i1="12"><s1>Centre for Cognition and Brain Disorders (CBBD), Normal University Hangzhou</s1><s2>Hangzhou</s2><s3>CHN</s3><sZ>12 aut.</sZ></fA14><fA15 i1="01"><s1>Neuroscience of Emotion and Affective Dynamics' Laboratory, Department of Psychology and Swiss Center for Affective Sciences, Campus Biotech, University of Geneva</s1> <s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></fA15><fA20><s1>139-144</s1></fA20><fA21><s1>2014</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>4814</s2><s5>354000502694640100</s5></fA43><fA44><s0>0000</s0><s1>© 2014 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>1 p.1/4</s0></fA45><fA47 i1="01" i2="1"><s0>14-0278836</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Cortex : (Testo stampato)</s0></fA64><fA66 i1="01"><s0>GBR</s0></fA66><fC01 i1="01" l="ENG"><s0>High activity of the default mode network (DMN) has been proposed to be central in processing self-relevant events. Thus far, this hypothesis of DMN function has not been tested directly using neurophysiological techniques. To test for the link between frontal midline DMN activity and self-relevant processing we measured neuronal activity (single-neurons' firing rates) in human subcallosal cingulate cortex (SCC) in the course of Deep Brain Stimulation surgery. We find that firing rates in SCC did not change during the presentation of specifically self-relevant stimuli when compared to the preceding pre-stimulus resting state level. In contrast, we observed significant changes in firing rates during other names in SCC. Such rest-self overlap seems to be specific for SCC since increase in firing rates in response to self-relevant stimuli were observed in another region, the subthalamic nucleus, in a group of Parkinson patients receiving deep brain stimulation surgery. These results suggest specific relationship between resting state and self-related activity, rest-self overlap, in specifically SCC as core region of the default-mode network.</s0></fC01><fC02 i1="01" i2="X"><s0>002A26C07</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Repos</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Rest</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Descanso</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Soi</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Self</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Si mismo</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Intracérébral</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Intracerebral</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Intracerebral</s0><s5>03</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Cortex cingulaire</s0><s5>04</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Cingulate cortex</s0><s5>04</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Corteza cingular</s0><s5>04</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Homme</s0><s5>18</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Human</s0><s5>18</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Hombre</s0><s5>18</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Réseau du mode par défaut</s0><s4>CD</s4><s5>96</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Default mode network</s0><s4>CD</s4><s5>96</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Red por defecto</s0><s4>CD</s4><s5>96</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Stimulation cérébrale profonde</s0><s4>CD</s4><s5>97</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Deep brain stimulation</s0><s4>CD</s4><s5>97</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Estimulación cerebral profunda</s0><s4>CD</s4><s5>97</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Encéphale</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Encephalon</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux central</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Central nervous system</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervioso central</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Traitement</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Treatment</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Tratamiento</s0><s5>39</s5></fC07><fN21><s1>349</s1></fN21></pA></standard></inist><affiliations><list><country><li>Allemagne</li><li>Canada</li><li>Japon</li><li>République populaire de Chine</li><li>Taïwan</li></country><region><li>Basse-Saxe</li><li>Ontario</li><li>Zhejiang</li></region><settlement><li>Hangzhou</li><li>Hanovre</li><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><region name="Ontario"><name sortKey="Lipsman, Nir" sort="Lipsman, Nir" uniqKey="Lipsman N" first="Nir" last="Lipsman">Nir Lipsman</name></region><name sortKey="Anderson, Adam" sort="Anderson, Adam" uniqKey="Anderson A" first="Adam" last="Anderson">Adam Anderson</name><name sortKey="Dostrousky, Jonathan O" sort="Dostrousky, Jonathan O" uniqKey="Dostrousky J" first="Jonathan O." last="Dostrousky">Jonathan O. Dostrousky</name><name sortKey="Giacobbe, Peter" sort="Giacobbe, Peter" uniqKey="Giacobbe P" first="Peter" last="Giacobbe">Peter Giacobbe</name><name sortKey="Hamani, Clement" sort="Hamani, Clement" uniqKey="Hamani C" first="Clement" last="Hamani">Clement Hamani</name><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D." last="Hutchison">William D. Hutchison</name><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M." last="Lozano">Andres M. Lozano</name><name sortKey="Northoff, Georg" sort="Northoff, Georg" uniqKey="Northoff G" first="Georg" last="Northoff">Georg Northoff</name><name sortKey="Womelsdorf, Thilo" sort="Womelsdorf, Thilo" uniqKey="Womelsdorf T" first="Thilo" last="Womelsdorf">Thilo Womelsdorf</name></country><country name="Japon"><noRegion><name sortKey="Nakao, Takashi" sort="Nakao, Takashi" uniqKey="Nakao T" first="Takashi" last="Nakao">Takashi Nakao</name></noRegion><name sortKey="Kanayama, Noriaki" sort="Kanayama, Noriaki" uniqKey="Kanayama N" first="Noriaki" last="Kanayama">Noriaki Kanayama</name></country><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Krauss, Joachim K" sort="Krauss, Joachim K" uniqKey="Krauss J" first="Joachim K." last="Krauss">Joachim K. Krauss</name></region></country><country name="Taïwan"><noRegion><name sortKey="Northoff, Georg" sort="Northoff, Georg" uniqKey="Northoff G" first="Georg" last="Northoff">Georg Northoff</name></noRegion><name sortKey="Northoff, Georg" sort="Northoff, Georg" uniqKey="Northoff G" first="Georg" last="Northoff">Georg Northoff</name></country><country name="République populaire de Chine"><region name="Zhejiang"><name sortKey="Northoff, Georg" sort="Northoff, Georg" uniqKey="Northoff G" first="Georg" last="Northoff">Georg Northoff</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PascalFrancis/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000009 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Checkpoint/biblio.hfd -nk 000009 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= PascalFrancis
|étape= Checkpoint
|type= RBID
|clé= Pascal:14-0278836
|texte= Neural overlap between resting state and self-relevant activity in human subcallosal cingulate cortex - Single unit recording in an intracranial study
}}
| This area was generated with Dilib version V0.6.29. |  |