La maladie de Parkinson au Canada (serveur d'exploration)

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Factors associated with the development of impulse compulsive disorders in Parkinson patients.

Identifieur interne : 001363 ( Ncbi/Merge ); précédent : 001362; suivant : 001364

Factors associated with the development of impulse compulsive disorders in Parkinson patients.

Auteurs : Abdul Qayyum Rana [Canada] ; Wasim Mansoor ; Syed Hussaini ; Abdullah Al Mosabbir ; Maniza Rahman ; Labiba Rahman

Source :

RBID : pubmed:23336737

Descripteurs français

English descriptors

Abstract

The aim of this study is to identify the prevalence of impulse compulsive disorder (ICD) in Parkinson's disease (PD) patients and to study potential associative factors that may be related to the onset of ICD while on parkinsonian medications.

DOI: 10.3109/00207454.2013.768243
PubMed: 23336737

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pubmed:23336737

Le document en format XML

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<name sortKey="Rana, Abdul Qayyum" sort="Rana, Abdul Qayyum" uniqKey="Rana A" first="Abdul Qayyum" last="Rana">Abdul Qayyum Rana</name>
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<nlm:affiliation>Parkinson's Clinic of Eastern Toronto and Movement Disorders Center, Toronto, ON, Canada. ranaaq@yahoo.com</nlm:affiliation>
<country xml:lang="fr">Canada</country>
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<wicri:noRegion>ON</wicri:noRegion>
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<name sortKey="Mansoor, Wasim" sort="Mansoor, Wasim" uniqKey="Mansoor W" first="Wasim" last="Mansoor">Wasim Mansoor</name>
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<name sortKey="Hussaini, Syed" sort="Hussaini, Syed" uniqKey="Hussaini S" first="Syed" last="Hussaini">Syed Hussaini</name>
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<name sortKey="Al Mosabbir, Abdullah" sort="Al Mosabbir, Abdullah" uniqKey="Al Mosabbir A" first="Abdullah" last="Al Mosabbir">Abdullah Al Mosabbir</name>
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<term>Disruptive, Impulse Control, and Conduct Disorders (chemically induced)</term>
<term>Disruptive, Impulse Control, and Conduct Disorders (complications)</term>
<term>Disruptive, Impulse Control, and Conduct Disorders (epidemiology)</term>
<term>Dopamine Agonists (administration & dosage)</term>
<term>Dopamine Agonists (adverse effects)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (epidemiology)</term>
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<term>Parkinson Disease</term>
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<term>Age of Onset</term>
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<div type="abstract" xml:lang="en">The aim of this study is to identify the prevalence of impulse compulsive disorder (ICD) in Parkinson's disease (PD) patients and to study potential associative factors that may be related to the onset of ICD while on parkinsonian medications.</div>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The aim of this study is to identify the prevalence of impulse compulsive disorder (ICD) in Parkinson's disease (PD) patients and to study potential associative factors that may be related to the onset of ICD while on parkinsonian medications.</AbstractText>
<AbstractText Label="METHOD" NlmCategory="METHODS">The study was conducted in two parts. In Part A, the prevalence of ICD in 140 PD patients was first assessed, followed by identifying any common variables that may be associated with the development of ICD. Finally, using a detailed chart review, Part B of the study examined the prevalence of ICD in all patients who presented with identical risk factors gathered in Part A.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of the 140 patients, 8 patients developed symptoms of ICD. Seven of these patients were found to have five common variables that included gender (males), stages 1-2 of PD, young onset of PD, maximum dosage of the drug and the use of dopamine agonists (DAs). Of the 140 patients, 22 patients fit the above-mentioned five criteria and of those 22 patients, 33% developed symptoms of ICD.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The use of DA therapy in the treatment of PD patients should be carefully monitored, especially in younger male patients who exhibit early signs of parkinsonian symptoms. As such, it is crucial for physicians to adjust DA dosages while also seeking alternative treatments to avoid the risk of ICD while on DAs.</AbstractText>
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