ParkinsonCanadaV1, Ncbi, Merge, bibRecord, 000543

Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis.

Identifieur interne : 000543 ( Ncbi/Merge ); précédent : 000542; suivant : 000544

Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis.

Auteurs : Mahyar Etminan [Canada] ; Sudeep S. Gill ; Ali Samii

Source :

The Lancet. Neurology [ 1474-4422 ] ; 2005.

RBID : pubmed:15907740

English descriptors

KwdEn :
- Ascorbic Acid (therapeutic use), Carotenoids (therapeutic use), Humans, Parkinson Disease (diet therapy), Parkinson Disease (epidemiology), Parkinson Disease (prevention & control), Risk Factors, Vitamin E (therapeutic use), beta Carotene (therapeutic use).
MESH :
- chemical , therapeutic use : Ascorbic Acid, Carotenoids, Vitamin E, beta Carotene.
- diet therapy : Parkinson Disease.
- epidemiology : Parkinson Disease.
- prevention & control : Parkinson Disease.
- Humans, Risk Factors.

Abstract

We studied the effect of vitamin C, vitamin E, and beta carotene intake on the risk of Parkinson's disease (PD). We did a systematic review and meta-analysis of observational studies published between 1966 and March 2005 searching MEDLINE, EMBASE, and the Cochrane Library. Eight studies were identified (six case-control, one cohort, and one cross-sectional). We found that dietary intake of vitamin E protects against PD. This protective influence was seen with both moderate intake (relative risk 0.81, 95% CI 0.67-0.98) and high intake (0.78, 0.57-1.06) of vitamin E, although the possible benefit associated with high intake of vitamin E was not significant. The studies did not suggest any protective effects associated with vitamin C or beta carotene. We conclude that dietary vitamin E may have a neuroprotective effect attenuating the risk of PD. These results require confirmation in randomised controlled trials.

DOI: 10.1016/S1474-4422(05)70097-1
PubMed: 15907740

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pubmed:15907740

Le document en format XML

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La maladie de Parkinson au Canada (serveur d'exploration)

Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis.

Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis.

Source :

English descriptors

Abstract

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