Patterns of Longitudinal Neural Activity Linked to Different Cognitive Profiles in Parkinson's Disease
Identifieur interne : 002164 ( Ncbi/Curation ); précédent : 002163; suivant : 002165Patterns of Longitudinal Neural Activity Linked to Different Cognitive Profiles in Parkinson's Disease
Auteurs : Atsuko Nagano-Saito [Canada] ; Mohamed S. Al-Azzawi [Canada] ; Alexandru Hanganu [Canada] ; Clotilde Degroot [Canada] ; Béatriz Mejia-Constain [Canada] ; Christophe Bedetti [Canada] ; Anne-Louise Lafontaine [Canada] ; Valérie Soland [Canada] ; Sylvain Chouinard [Canada] ; Oury Monchi [Canada]Source :
- Frontiers in Aging Neuroscience [ 1663-4365 ] ; 2016.
Abstract
Mild cognitive impairment in Parkinson's disease (PD) has been linked with functional brain changes. Previously, using functional magnetic resonance imaging (fMRI), we reported reduced cortico-striatal activity in patients with PD who also had mild cognitive impairment (MCI) vs. those who did not (non-MCI). We followed up these patients to investigate the longitudinal effect on the neural activity. Twenty-four non-demented patients with Parkinson's disease (non-MCI: 12, MCI: 12) were included in the study. Each participant underwent two fMRIs while performing the Wisconsin Card Sorting Task 20 months apart. The non-MCI patients recruited the usual cognitive corticostriatal loop at the first and second sessions (Time 1 and Time 2, respectively). However, decreased activity was observed in the cerebellum and occipital area and increased activity was observed in the medial prefrontal cortex and parietal lobe during planning set-shift at Time 2. Increased activity in the precuneus was also demonstrated while executing set-shifts at Time 2. The MCI patients revealed more activity in the frontal, parietal and occipital lobes during planning set-shifts, and in the parietal and occipital lobes, precuneus, and cerebellum, during executing set-shift at Time 2. Analysis regrouping of both groups of PD patients revealed that hippocampal and thalamic activity at Time 1 was associated with less cognitive decline over time. Our results reveal that functional alteration along the time-points differed between the non-MCI and MCI patients. They also underline the importance of preserving thalamic and hippocampal function with respect to cognitive decline over time.
Url:
DOI: 10.3389/fnagi.2016.00275
PubMed: 27932974
PubMed Central: 5120116
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000962
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000962
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000083
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000120
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000120
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000120
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :002164
Links to Exploration step
PMC:5120116Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Patterns of Longitudinal Neural Activity Linked to Different Cognitive Profiles in Parkinson's Disease</title>
<author><name sortKey="Nagano Saito, Atsuko" sort="Nagano Saito, Atsuko" uniqKey="Nagano Saito A" first="Atsuko" last="Nagano-Saito">Atsuko Nagano-Saito</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Al Azzawi, Mohamed S" sort="Al Azzawi, Mohamed S" uniqKey="Al Azzawi M" first="Mohamed S." last="Al-Azzawi">Mohamed S. Al-Azzawi</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hanganu, Alexandru" sort="Hanganu, Alexandru" uniqKey="Hanganu A" first="Alexandru" last="Hanganu">Alexandru Hanganu</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Departments of Clinical Neurosciences and Radiology, University of Calgary</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Hotchkiss Brain Institute</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Degroot, Clotilde" sort="Degroot, Clotilde" uniqKey="Degroot C" first="Clotilde" last="Degroot">Clotilde Degroot</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mejia Constain, Beatriz" sort="Mejia Constain, Beatriz" uniqKey="Mejia Constain B" first="Béatriz" last="Mejia-Constain">Béatriz Mejia-Constain</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bedetti, Christophe" sort="Bedetti, Christophe" uniqKey="Bedetti C" first="Christophe" last="Bedetti">Christophe Bedetti</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lafontaine, Anne Louise" sort="Lafontaine, Anne Louise" uniqKey="Lafontaine A" first="Anne-Louise" last="Lafontaine">Anne-Louise Lafontaine</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Neurology and Neurosurgery, McGill University</institution>
<country>Montreal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Soland, Valerie" sort="Soland, Valerie" uniqKey="Soland V" first="Valérie" last="Soland">Valérie Soland</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Centre Hospitalier de l'Université de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chouinard, Sylvain" sort="Chouinard, Sylvain" uniqKey="Chouinard S" first="Sylvain" last="Chouinard">Sylvain Chouinard</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Centre Hospitalier de l'Université de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Departments of Clinical Neurosciences and Radiology, University of Calgary</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Hotchkiss Brain Institute</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Neurology and Neurosurgery, McGill University</institution>
<country>Montreal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27932974</idno>
<idno type="pmc">5120116</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120116</idno>
<idno type="RBID">PMC:5120116</idno>
<idno type="doi">10.3389/fnagi.2016.00275</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000962</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000962</idno>
<idno type="wicri:Area/Pmc/Curation">000962</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000962</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000083</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000083</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">000120</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000120</idno>
<idno type="wicri:Area/PubMed/Curation">000120</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000120</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000120</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000120</idno>
<idno type="wicri:Area/Ncbi/Merge">002164</idno>
<idno type="wicri:Area/Ncbi/Curation">002164</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Patterns of Longitudinal Neural Activity Linked to Different Cognitive Profiles in Parkinson's Disease</title>
<author><name sortKey="Nagano Saito, Atsuko" sort="Nagano Saito, Atsuko" uniqKey="Nagano Saito A" first="Atsuko" last="Nagano-Saito">Atsuko Nagano-Saito</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Al Azzawi, Mohamed S" sort="Al Azzawi, Mohamed S" uniqKey="Al Azzawi M" first="Mohamed S." last="Al-Azzawi">Mohamed S. Al-Azzawi</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hanganu, Alexandru" sort="Hanganu, Alexandru" uniqKey="Hanganu A" first="Alexandru" last="Hanganu">Alexandru Hanganu</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Departments of Clinical Neurosciences and Radiology, University of Calgary</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Hotchkiss Brain Institute</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Degroot, Clotilde" sort="Degroot, Clotilde" uniqKey="Degroot C" first="Clotilde" last="Degroot">Clotilde Degroot</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mejia Constain, Beatriz" sort="Mejia Constain, Beatriz" uniqKey="Mejia Constain B" first="Béatriz" last="Mejia-Constain">Béatriz Mejia-Constain</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bedetti, Christophe" sort="Bedetti, Christophe" uniqKey="Bedetti C" first="Christophe" last="Bedetti">Christophe Bedetti</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lafontaine, Anne Louise" sort="Lafontaine, Anne Louise" uniqKey="Lafontaine A" first="Anne-Louise" last="Lafontaine">Anne-Louise Lafontaine</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Neurology and Neurosurgery, McGill University</institution>
<country>Montreal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Soland, Valerie" sort="Soland, Valerie" uniqKey="Soland V" first="Valérie" last="Soland">Valérie Soland</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Centre Hospitalier de l'Université de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chouinard, Sylvain" sort="Chouinard, Sylvain" uniqKey="Chouinard S" first="Sylvain" last="Chouinard">Sylvain Chouinard</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Centre Hospitalier de l'Université de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal</institution>
<country>Montréal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Departments of Clinical Neurosciences and Radiology, University of Calgary</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Hotchkiss Brain Institute</institution>
<country>Calgary, AB, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Neurology and Neurosurgery, McGill University</institution>
<country>Montreal, QC, Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea></wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Frontiers in Aging Neuroscience</title>
<idno type="eISSN">1663-4365</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Mild cognitive impairment in Parkinson's disease (PD) has been linked with functional brain changes. Previously, using functional magnetic resonance imaging (fMRI), we reported reduced cortico-striatal activity in patients with PD who also had mild cognitive impairment (MCI) vs. those who did not (non-MCI). We followed up these patients to investigate the longitudinal effect on the neural activity. Twenty-four non-demented patients with Parkinson's disease (non-MCI: 12, MCI: 12) were included in the study. Each participant underwent two fMRIs while performing the Wisconsin Card Sorting Task 20 months apart. The non-MCI patients recruited the usual cognitive corticostriatal loop at the first and second sessions (Time 1 and Time 2, respectively). However, decreased activity was observed in the cerebellum and occipital area and increased activity was observed in the medial prefrontal cortex and parietal lobe during planning set-shift at Time 2. Increased activity in the precuneus was also demonstrated while executing set-shifts at Time 2. The MCI patients revealed more activity in the frontal, parietal and occipital lobes during planning set-shifts, and in the parietal and occipital lobes, precuneus, and cerebellum, during executing set-shift at Time 2. Analysis regrouping of both groups of PD patients revealed that hippocampal and thalamic activity at Time 1 was associated with less cognitive decline over time. Our results reveal that functional alteration along the time-points differed between the non-MCI and MCI patients. They also underline the importance of preserving thalamic and hippocampal function with respect to cognitive decline over time.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Amboni, M" uniqKey="Amboni M">M. Amboni</name>
</author>
<author><name sortKey="Tessitore, A" uniqKey="Tessitore A">A. Tessitore</name>
</author>
<author><name sortKey="Esposito, F" uniqKey="Esposito F">F. Esposito</name>
</author>
<author><name sortKey="Santangelo, G" uniqKey="Santangelo G">G. Santangelo</name>
</author>
<author><name sortKey="Picillo, M" uniqKey="Picillo M">M. Picillo</name>
</author>
<author><name sortKey="Vitale, C" uniqKey="Vitale C">C. Vitale</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Baggio, H C" uniqKey="Baggio H">H. C. Baggio</name>
</author>
<author><name sortKey="Segura, B" uniqKey="Segura B">B. Segura</name>
</author>
<author><name sortKey="Sala Llonch, R" uniqKey="Sala Llonch R">R. Sala-Llonch</name>
</author>
<author><name sortKey="Marti, M J" uniqKey="Marti M">M. J. Marti</name>
</author>
<author><name sortKey="Valldeoriola, F" uniqKey="Valldeoriola F">F. Valldeoriola</name>
</author>
<author><name sortKey="Compta, Y" uniqKey="Compta Y">Y. Compta</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Behrens, T E" uniqKey="Behrens T">T. E. Behrens</name>
</author>
<author><name sortKey="Johansen Berg, H" uniqKey="Johansen Berg H">H. Johansen-Berg</name>
</author>
<author><name sortKey="Woolrich, M W" uniqKey="Woolrich M">M. W. Woolrich</name>
</author>
<author><name sortKey="Smith, S M" uniqKey="Smith S">S. M. Smith</name>
</author>
<author><name sortKey="Wheeler Kingshott, C A" uniqKey="Wheeler Kingshott C">C. A. Wheeler-Kingshott</name>
</author>
<author><name sortKey="Boulby, P A" uniqKey="Boulby P">P. A. Boulby</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bernier, P M" uniqKey="Bernier P">P. M. Bernier</name>
</author>
<author><name sortKey="Grafton, S T" uniqKey="Grafton S">S. T. Grafton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Binkofski, F" uniqKey="Binkofski F">F. Binkofski</name>
</author>
<author><name sortKey="Buxbaum, L J" uniqKey="Buxbaum L">L. J. Buxbaum</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bohnen, N I" uniqKey="Bohnen N">N. I. Bohnen</name>
</author>
<author><name sortKey="Minoshima, S" uniqKey="Minoshima S">S. Minoshima</name>
</author>
<author><name sortKey="Giordani, B" uniqKey="Giordani B">B. Giordani</name>
</author>
<author><name sortKey="Frey, K A" uniqKey="Frey K">K. A. Frey</name>
</author>
<author><name sortKey="Kuhl, D E" uniqKey="Kuhl D">D. E. Kuhl</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Burgess, P W" uniqKey="Burgess P">P. W. Burgess</name>
</author>
<author><name sortKey="Shallice, T" uniqKey="Shallice T">T. Shallice</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Carbon, M" uniqKey="Carbon M">M. Carbon</name>
</author>
<author><name sortKey="Reetz, K" uniqKey="Reetz K">K. Reetz</name>
</author>
<author><name sortKey="Ghilardi, M F" uniqKey="Ghilardi M">M. F. Ghilardi</name>
</author>
<author><name sortKey="Dhawan, V" uniqKey="Dhawan V">V. Dhawan</name>
</author>
<author><name sortKey="Eidelberg, D" uniqKey="Eidelberg D">D. Eidelberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, F X" uniqKey="Chen F">F. X. Chen</name>
</author>
<author><name sortKey="Kang, D Z" uniqKey="Kang D">D. Z. Kang</name>
</author>
<author><name sortKey="Chen, F Y" uniqKey="Chen F">F. Y. Chen</name>
</author>
<author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name>
</author>
<author><name sortKey="Wu, G" uniqKey="Wu G">G. Wu</name>
</author>
<author><name sortKey="Li, X" uniqKey="Li X">X. Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Collins, D L" uniqKey="Collins D">D. L. Collins</name>
</author>
<author><name sortKey="Neelin, P" uniqKey="Neelin P">P. Neelin</name>
</author>
<author><name sortKey="Peters, T M" uniqKey="Peters T">T. M. Peters</name>
</author>
<author><name sortKey="Evans, A C" uniqKey="Evans A">A. C. Evans</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Culbertson, C W" uniqKey="Culbertson C">C. W. Culbertson</name>
</author>
<author><name sortKey="Zillmer, E A" uniqKey="Zillmer E">E. A. Zillmer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dalrymple Alford, J C" uniqKey="Dalrymple Alford J">J. C. Dalrymple-Alford</name>
</author>
<author><name sortKey="Livingston, L" uniqKey="Livingston L">L. Livingston</name>
</author>
<author><name sortKey="Macaskill, M R" uniqKey="Macaskill M">M. R. Macaskill</name>
</author>
<author><name sortKey="Graham, C" uniqKey="Graham C">C. Graham</name>
</author>
<author><name sortKey="Melzer, T R" uniqKey="Melzer T">T. R. Melzer</name>
</author>
<author><name sortKey="Porter, R J" uniqKey="Porter R">R. J. Porter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ekman, U" uniqKey="Ekman U">U. Ekman</name>
</author>
<author><name sortKey="Eriksson, J" uniqKey="Eriksson J">J. Eriksson</name>
</author>
<author><name sortKey="Forsgren, L" uniqKey="Forsgren L">L. Forsgren</name>
</author>
<author><name sortKey="Domellof, M E" uniqKey="Domellof M">M. E. Domellöf</name>
</author>
<author><name sortKey="Elgh, E" uniqKey="Elgh E">E. Elgh</name>
</author>
<author><name sortKey="Lundquist, A" uniqKey="Lundquist A">A. Lundquist</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ekman, U" uniqKey="Ekman U">U. Ekman</name>
</author>
<author><name sortKey="Eriksson, J" uniqKey="Eriksson J">J. Eriksson</name>
</author>
<author><name sortKey="Forsgren, L" uniqKey="Forsgren L">L. Forsgren</name>
</author>
<author><name sortKey="Mo, S J" uniqKey="Mo S">S. J. Mo</name>
</author>
<author><name sortKey="Riklund, K" uniqKey="Riklund K">K. Riklund</name>
</author>
<author><name sortKey="Nyberg, L" uniqKey="Nyberg L">L. Nyberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Euston, D R" uniqKey="Euston D">D. R. Euston</name>
</author>
<author><name sortKey="Gruber, A J" uniqKey="Gruber A">A. J. Gruber</name>
</author>
<author><name sortKey="Mcnaughton, B L" uniqKey="Mcnaughton B">B. L. Mcnaughton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Foltynie, T" uniqKey="Foltynie T">T. Foltynie</name>
</author>
<author><name sortKey="Brayne, C E" uniqKey="Brayne C">C. E. Brayne</name>
</author>
<author><name sortKey="Robbins, T W" uniqKey="Robbins T">T. W. Robbins</name>
</author>
<author><name sortKey="Barker, R A" uniqKey="Barker R">R. A. Barker</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Golden, C J" uniqKey="Golden C">C. J. Golden</name>
</author>
<author><name sortKey="Freshwater, S M" uniqKey="Freshwater S">S. M. Freshwater</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Goldman, J G" uniqKey="Goldman J">J. G. Goldman</name>
</author>
<author><name sortKey="Holden, S" uniqKey="Holden S">S. Holden</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hanganu, A" uniqKey="Hanganu A">A. Hanganu</name>
</author>
<author><name sortKey="Bedetti, C" uniqKey="Bedetti C">C. Bedetti</name>
</author>
<author><name sortKey="Degroot, C" uniqKey="Degroot C">C. Degroot</name>
</author>
<author><name sortKey="Mejia Constain, B" uniqKey="Mejia Constain B">B. Mejia-Constain</name>
</author>
<author><name sortKey="Lafontaine, A L" uniqKey="Lafontaine A">A. L. Lafontaine</name>
</author>
<author><name sortKey="Soland, V" uniqKey="Soland V">V. Soland</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hanganu, A" uniqKey="Hanganu A">A. Hanganu</name>
</author>
<author><name sortKey="Bedetti, C" uniqKey="Bedetti C">C. Bedetti</name>
</author>
<author><name sortKey="Jubault, T" uniqKey="Jubault T">T. Jubault</name>
</author>
<author><name sortKey="Gagnon, J F" uniqKey="Gagnon J">J. F. Gagnon</name>
</author>
<author><name sortKey="Mejia Constain, B" uniqKey="Mejia Constain B">B. Mejia-Constain</name>
</author>
<author><name sortKey="Degroot, C" uniqKey="Degroot C">C. Degroot</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Herkenham, M" uniqKey="Herkenham M">M. Herkenham</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hooper, H E" uniqKey="Hooper H">H. E. Hooper</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hughes, A J" uniqKey="Hughes A">A. J. Hughes</name>
</author>
<author><name sortKey="Daniel, S E" uniqKey="Daniel S">S. E. Daniel</name>
</author>
<author><name sortKey="Kilford, L" uniqKey="Kilford L">L. Kilford</name>
</author>
<author><name sortKey="Lees, A J" uniqKey="Lees A">A. J. Lees</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Joanette, Y" uniqKey="Joanette Y">Y. Joanette</name>
</author>
<author><name sortKey="Ska, B" uniqKey="Ska B">B. Ska</name>
</author>
<author><name sortKey="Cote, H" uniqKey="Cote H">H. Côté</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jubault, T" uniqKey="Jubault T">T. Jubault</name>
</author>
<author><name sortKey="Brambati, S M" uniqKey="Brambati S">S. M. Brambati</name>
</author>
<author><name sortKey="Degroot, C" uniqKey="Degroot C">C. Degroot</name>
</author>
<author><name sortKey="Kullmann, B" uniqKey="Kullmann B">B. Kullmann</name>
</author>
<author><name sortKey="Strafella, A P" uniqKey="Strafella A">A. P. Strafella</name>
</author>
<author><name sortKey="Lafontaine, A L" uniqKey="Lafontaine A">A. L. Lafontaine</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kaplan, E" uniqKey="Kaplan E">E. Kaplan</name>
</author>
<author><name sortKey="Goodglass, H" uniqKey="Goodglass H">H. Goodglass</name>
</author>
<author><name sortKey="Weintraub, S" uniqKey="Weintraub S">S. Weintraub</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Laird, A R" uniqKey="Laird A">A. R. Laird</name>
</author>
<author><name sortKey="Eickhoff, S B" uniqKey="Eickhoff S">S. B. Eickhoff</name>
</author>
<author><name sortKey="Li, K" uniqKey="Li K">K. Li</name>
</author>
<author><name sortKey="Robin, D A" uniqKey="Robin D">D. A. Robin</name>
</author>
<author><name sortKey="Glahn, D C" uniqKey="Glahn D">D. C. Glahn</name>
</author>
<author><name sortKey="Fox, P T" uniqKey="Fox P">P. T. Fox</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lewis, S J" uniqKey="Lewis S">S. J. Lewis</name>
</author>
<author><name sortKey="Dove, A" uniqKey="Dove A">A. Dove</name>
</author>
<author><name sortKey="Robbins, T W" uniqKey="Robbins T">T. W. Robbins</name>
</author>
<author><name sortKey="Barker, R A" uniqKey="Barker R">R. A. Barker</name>
</author>
<author><name sortKey="Owen, A M" uniqKey="Owen A">A. M. Owen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Litvan, I" uniqKey="Litvan I">I. Litvan</name>
</author>
<author><name sortKey="Goldman, J G" uniqKey="Goldman J">J. G. Goldman</name>
</author>
<author><name sortKey="Troster, A I" uniqKey="Troster A">A. I. Tröster</name>
</author>
<author><name sortKey="Schmand, B A" uniqKey="Schmand B">B. A. Schmand</name>
</author>
<author><name sortKey="Weintraub, D" uniqKey="Weintraub D">D. Weintraub</name>
</author>
<author><name sortKey="Petersen, R C" uniqKey="Petersen R">R. C. Petersen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Margulies, D S" uniqKey="Margulies D">D. S. Margulies</name>
</author>
<author><name sortKey="Vincent, J L" uniqKey="Vincent J">J. L. Vincent</name>
</author>
<author><name sortKey="Kelly, C" uniqKey="Kelly C">C. Kelly</name>
</author>
<author><name sortKey="Lohmann, G" uniqKey="Lohmann G">G. Lohmann</name>
</author>
<author><name sortKey="Uddin, L Q" uniqKey="Uddin L">L. Q. Uddin</name>
</author>
<author><name sortKey="Biswal, B B" uniqKey="Biswal B">B. B. Biswal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Martinu, K" uniqKey="Martinu K">K. Martinu</name>
</author>
<author><name sortKey="Monchi, O" uniqKey="Monchi O">O. Monchi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Monchi, O" uniqKey="Monchi O">O. Monchi</name>
</author>
<author><name sortKey="Petrides, M" uniqKey="Petrides M">M. Petrides</name>
</author>
<author><name sortKey="Doyon, J" uniqKey="Doyon J">J. Doyon</name>
</author>
<author><name sortKey="Postuma, R B" uniqKey="Postuma R">R. B. Postuma</name>
</author>
<author><name sortKey="Worsley, K" uniqKey="Worsley K">K. Worsley</name>
</author>
<author><name sortKey="Dagher, A" uniqKey="Dagher A">A. Dagher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Monchi, O" uniqKey="Monchi O">O. Monchi</name>
</author>
<author><name sortKey="Petrides, M" uniqKey="Petrides M">M. Petrides</name>
</author>
<author><name sortKey="Mejia Constain, B" uniqKey="Mejia Constain B">B. Mejia-Constain</name>
</author>
<author><name sortKey="Strafella, A P" uniqKey="Strafella A">A. P. Strafella</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Monchi, O" uniqKey="Monchi O">O. Monchi</name>
</author>
<author><name sortKey="Petrides, M" uniqKey="Petrides M">M. Petrides</name>
</author>
<author><name sortKey="Petre, V" uniqKey="Petre V">V. Petre</name>
</author>
<author><name sortKey="Worsley, K" uniqKey="Worsley K">K. Worsley</name>
</author>
<author><name sortKey="Dagher, A" uniqKey="Dagher A">A. Dagher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nagano Saito, A" uniqKey="Nagano Saito A">A. Nagano-Saito</name>
</author>
<author><name sortKey="Habak, C" uniqKey="Habak C">C. Habak</name>
</author>
<author><name sortKey="Mejia Constain, B" uniqKey="Mejia Constain B">B. Mejía-Constaín</name>
</author>
<author><name sortKey="Degroot, C" uniqKey="Degroot C">C. Degroot</name>
</author>
<author><name sortKey="Monetta, L" uniqKey="Monetta L">L. Monetta</name>
</author>
<author><name sortKey="Jubault, T" uniqKey="Jubault T">T. Jubault</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nagano Saito, A" uniqKey="Nagano Saito A">A. Nagano-Saito</name>
</author>
<author><name sortKey="Kato, T" uniqKey="Kato T">T. Kato</name>
</author>
<author><name sortKey="Arahata, Y" uniqKey="Arahata Y">Y. Arahata</name>
</author>
<author><name sortKey="Washimi, Y" uniqKey="Washimi Y">Y. Washimi</name>
</author>
<author><name sortKey="Nakamura, A" uniqKey="Nakamura A">A. Nakamura</name>
</author>
<author><name sortKey="Abe, Y" uniqKey="Abe Y">Y. Abe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nagano Saito, A" uniqKey="Nagano Saito A">A. Nagano-Saito</name>
</author>
<author><name sortKey="Leyton, M" uniqKey="Leyton M">M. Leyton</name>
</author>
<author><name sortKey="Monchi, O" uniqKey="Monchi O">O. Monchi</name>
</author>
<author><name sortKey="Goldberg, Y K" uniqKey="Goldberg Y">Y. K. Goldberg</name>
</author>
<author><name sortKey="He, Y" uniqKey="He Y">Y. He</name>
</author>
<author><name sortKey="Dagher, A" uniqKey="Dagher A">A. Dagher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nagano Saito, A" uniqKey="Nagano Saito A">A. Nagano-Saito</name>
</author>
<author><name sortKey="Washimi, Y" uniqKey="Washimi Y">Y. Washimi</name>
</author>
<author><name sortKey="Arahata, Y" uniqKey="Arahata Y">Y. Arahata</name>
</author>
<author><name sortKey="Kachi, T" uniqKey="Kachi T">T. Kachi</name>
</author>
<author><name sortKey="Lerch, J P" uniqKey="Lerch J">J. P. Lerch</name>
</author>
<author><name sortKey="Evans, A C" uniqKey="Evans A">A. C. Evans</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nakao, T" uniqKey="Nakao T">T. Nakao</name>
</author>
<author><name sortKey="Ohira, H" uniqKey="Ohira H">H. Ohira</name>
</author>
<author><name sortKey="Northoff, G" uniqKey="Northoff G">G. Northoff</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nasreddine, Z S" uniqKey="Nasreddine Z">Z. S. Nasreddine</name>
</author>
<author><name sortKey="Phillips, N A" uniqKey="Phillips N">N. A. Phillips</name>
</author>
<author><name sortKey="Bedirian, V" uniqKey="Bedirian V">V. Bédirian</name>
</author>
<author><name sortKey="Charbonneau, S" uniqKey="Charbonneau S">S. Charbonneau</name>
</author>
<author><name sortKey="Whitehead, V" uniqKey="Whitehead V">V. Whitehead</name>
</author>
<author><name sortKey="Collin, I" uniqKey="Collin I">I. Collin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Reitan, R M" uniqKey="Reitan R">R. M. Reitan</name>
</author>
<author><name sortKey="Wolfson, D" uniqKey="Wolfson D">D. Wolfson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rizzolatti, G" uniqKey="Rizzolatti G">G. Rizzolatti</name>
</author>
<author><name sortKey="Matelli, M" uniqKey="Matelli M">M. Matelli</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schmidt, M" uniqKey="Schmidt M">M. Schmidt</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shulman, K I" uniqKey="Shulman K">K. I. Shulman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shulman, K I" uniqKey="Shulman K">K. I. Shulman</name>
</author>
<author><name sortKey="Pushkar Gold, D" uniqKey="Pushkar Gold D">D. Pushkar Gold</name>
</author>
<author><name sortKey="Cohen, C A" uniqKey="Cohen C">C. A. Cohen</name>
</author>
<author><name sortKey="Zucchero, C A" uniqKey="Zucchero C">C. A. Zucchero</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vertes, R P" uniqKey="Vertes R">R. P. Vertes</name>
</author>
<author><name sortKey="Hoover, W B" uniqKey="Hoover W">W. B. Hoover</name>
</author>
<author><name sortKey="Do Valle, A C" uniqKey="Do Valle A">A. C. Do Valle</name>
</author>
<author><name sortKey="Sherman, A" uniqKey="Sherman A">A. Sherman</name>
</author>
<author><name sortKey="Rodriguez, J J" uniqKey="Rodriguez J">J. J. Rodriguez</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vogt, B A" uniqKey="Vogt B">B. A. Vogt</name>
</author>
<author><name sortKey="Vogt, L J" uniqKey="Vogt L">L. J. Vogt</name>
</author>
<author><name sortKey="Perl, D P" uniqKey="Perl D">D. P. Perl</name>
</author>
<author><name sortKey="Hof, P R" uniqKey="Hof P">P. R. Hof</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wechsler, D" uniqKey="Wechsler D">D. Wechsler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wechsler, D" uniqKey="Wechsler D">D. Wechsler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Witjas, T" uniqKey="Witjas T">T. Witjas</name>
</author>
<author><name sortKey="Kaphan, E" uniqKey="Kaphan E">E. Kaphan</name>
</author>
<author><name sortKey="Azulay, J" uniqKey="Azulay J">J. Azulay</name>
</author>
<author><name sortKey="Blin, O" uniqKey="Blin O">O. Blin</name>
</author>
<author><name sortKey="Ceccaldi, M" uniqKey="Ceccaldi M">M. Ceccaldi</name>
</author>
<author><name sortKey="Pouget, J" uniqKey="Pouget J">J. Pouget</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Worsley, K J" uniqKey="Worsley K">K. J. Worsley</name>
</author>
<author><name sortKey="Liao, C H" uniqKey="Liao C">C. H. Liao</name>
</author>
<author><name sortKey="Aston, J" uniqKey="Aston J">J. Aston</name>
</author>
<author><name sortKey="Petre, V" uniqKey="Petre V">V. Petre</name>
</author>
<author><name sortKey="Duncan, G H" uniqKey="Duncan G">G. H. Duncan</name>
</author>
<author><name sortKey="Morales, F" uniqKey="Morales F">F. Morales</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wouterlood, F G" uniqKey="Wouterlood F">F. G. Wouterlood</name>
</author>
<author><name sortKey="Saldana, E" uniqKey="Saldana E">E. Saldana</name>
</author>
<author><name sortKey="Witter, M P" uniqKey="Witter M">M. P. Witter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zijdenbos, A P" uniqKey="Zijdenbos A">A. P. Zijdenbos</name>
</author>
<author><name sortKey="Forghani, R" uniqKey="Forghani R">R. Forghani</name>
</author>
<author><name sortKey="Evans, A C" uniqKey="Evans A">A. C. Evans</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002164 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 002164 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Canada |area= ParkinsonCanadaV1 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:5120116 |texte= Patterns of Longitudinal Neural Activity Linked to Different Cognitive Profiles in Parkinson's Disease }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:27932974" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a ParkinsonCanadaV1
This area was generated with Dilib version V0.6.29. |