DETECT--a density estimation tool for enzyme classification and its application to Plasmodium falciparum.
Identifieur interne : 000C73 ( Ncbi/Curation ); précédent : 000C72; suivant : 000C74DETECT--a density estimation tool for enzyme classification and its application to Plasmodium falciparum.
Auteurs : Stacy S. Hung [Canada] ; James Wasmuth ; Christopher Sanford ; John ParkinsonSource :
- Bioinformatics (Oxford, England) [ 1367-4811 ] ; 2010.
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Enzymes.
- chemical , classification : Enzymes.
- chemical , genetics : Enzymes, Proteins.
- genetics : Plasmodium falciparum.
- metabolism : Plasmodium falciparum.
- methods : Genomics.
- Databases, Protein, Sequence Alignment, Software.
Abstract
A major challenge in genomics is the accurate annotation of component genes. Enzymes are typically predicted using homology-based search methods, where the membership of a protein to an enzyme family is based on single-sequence comparisons. As such, these methods are often error-prone and lack useful measures of reliability for the prediction.
DOI: 10.1093/bioinformatics/btq266
PubMed: 20513663
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000D26
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000D26
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000D26
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000C73
Links to Exploration step
pubmed:20513663Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">DETECT--a density estimation tool for enzyme classification and its application to Plasmodium falciparum.</title><author><name sortKey="Hung, Stacy S" sort="Hung, Stacy S" uniqKey="Hung S" first="Stacy S" last="Hung">Stacy S. Hung</name><affiliation wicri:level="1"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 15-704 MaRS TMDT East, 101 College Street, Toronto, ON M5G 1L7, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 15-704 MaRS TMDT East, 101 College Street, Toronto, ON M5G 1L7</wicri:regionArea><wicri:noRegion>ON M5G 1L7</wicri:noRegion></affiliation></author><author><name sortKey="Wasmuth, James" sort="Wasmuth, James" uniqKey="Wasmuth J" first="James" last="Wasmuth">James Wasmuth</name></author><author><name sortKey="Sanford, Christopher" sort="Sanford, Christopher" uniqKey="Sanford C" first="Christopher" last="Sanford">Christopher Sanford</name></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:20513663</idno><idno type="pmid">20513663</idno><idno type="doi">10.1093/bioinformatics/btq266</idno><idno type="wicri:Area/PubMed/Corpus">000D26</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D26</idno><idno type="wicri:Area/PubMed/Curation">000D26</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000D26</idno><idno type="wicri:Area/PubMed/Checkpoint">000D26</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000D26</idno><idno type="wicri:Area/Ncbi/Merge">000C73</idno><idno type="wicri:Area/Ncbi/Curation">000C73</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">DETECT--a density estimation tool for enzyme classification and its application to Plasmodium falciparum.</title><author><name sortKey="Hung, Stacy S" sort="Hung, Stacy S" uniqKey="Hung S" first="Stacy S" last="Hung">Stacy S. Hung</name><affiliation wicri:level="1"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 15-704 MaRS TMDT East, 101 College Street, Toronto, ON M5G 1L7, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 15-704 MaRS TMDT East, 101 College Street, Toronto, ON M5G 1L7</wicri:regionArea><wicri:noRegion>ON M5G 1L7</wicri:noRegion></affiliation></author><author><name sortKey="Wasmuth, James" sort="Wasmuth, James" uniqKey="Wasmuth J" first="James" last="Wasmuth">James Wasmuth</name></author><author><name sortKey="Sanford, Christopher" sort="Sanford, Christopher" uniqKey="Sanford C" first="Christopher" last="Sanford">Christopher Sanford</name></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name></author></analytic><series><title level="j">Bioinformatics (Oxford, England)</title><idno type="eISSN">1367-4811</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Databases, Protein</term><term>Enzymes (chemistry)</term><term>Enzymes (classification)</term><term>Enzymes (genetics)</term><term>Genomics (methods)</term><term>Plasmodium falciparum (genetics)</term><term>Plasmodium falciparum (metabolism)</term><term>Proteins (genetics)</term><term>Sequence Alignment</term><term>Software</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Enzymes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="classification" xml:lang="en"><term>Enzymes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Enzymes</term><term>Proteins</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Plasmodium falciparum</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Plasmodium falciparum</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Genomics</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Databases, Protein</term><term>Sequence Alignment</term><term>Software</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A major challenge in genomics is the accurate annotation of component genes. Enzymes are typically predicted using homology-based search methods, where the membership of a protein to an enzyme family is based on single-sequence comparisons. As such, these methods are often error-prone and lack useful measures of reliability for the prediction.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C73 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000C73 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= pubmed:20513663
|texte= DETECT--a density estimation tool for enzyme classification and its application to Plasmodium falciparum.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:20513663" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |