Deep brain stimulation effects on memory.
Identifieur interne : 001299 ( Ncbi/Checkpoint ); précédent : 001298; suivant : 001300Deep brain stimulation effects on memory.
Auteurs : A W Laxton [Canada] ; T. Sankar ; A M Lozano ; C. HamaniSource :
- Journal of neurosurgical sciences [ 0390-5616 ] ; 2012.
English descriptors
- KwdEn :
- MESH :
- methods : Deep Brain Stimulation.
- physiology : Memory.
- physiopathology : Parkinson Disease, Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Humans.
Abstract
As the population of many countries ages, disorders of cognition and memory-such as Alzheimer's Disease (AD) and dementia associated with Parkinson's Disease-will become a major societal burden. At present, few effective medical therapies against these conditions are available. Deep brain stimulation (DBS) may be a potential therapeutic option, because it can directly target and modulate the activity of structures implicated in circuits subserving memory function. In this article, we review the scientific literature to address some of the mechanisms by which DBS may impact memory and cognition. We then summarize the results of recent clinical experience with DBS in AD and Parkinsonian dementia.
PubMed: 23111294
Affiliations:
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pubmed:23111294Le document en format XML
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Sankar</name></author><author><name sortKey="Lozano, A M" sort="Lozano, A M" uniqKey="Lozano A" first="A M" last="Lozano">A M Lozano</name></author><author><name sortKey="Hamani, C" sort="Hamani, C" uniqKey="Hamani C" first="C" last="Hamani">C. Hamani</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="RBID">pubmed:23111294</idno><idno type="pmid">23111294</idno><idno type="wicri:Area/PubMed/Corpus">000A06</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A06</idno><idno type="wicri:Area/PubMed/Curation">000A06</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A06</idno><idno type="wicri:Area/PubMed/Checkpoint">000A06</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A06</idno><idno type="wicri:Area/Ncbi/Merge">001299</idno><idno type="wicri:Area/Ncbi/Curation">001299</idno><idno type="wicri:Area/Ncbi/Checkpoint">001299</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Deep brain stimulation effects on memory.</title><author><name sortKey="Laxton, A W" sort="Laxton, A W" uniqKey="Laxton A" first="A W" last="Laxton">A W Laxton</name><affiliation wicri:level="4"><nlm:affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Sankar, T" sort="Sankar, T" uniqKey="Sankar T" first="T" last="Sankar">T. Sankar</name></author><author><name sortKey="Lozano, A M" sort="Lozano, A M" uniqKey="Lozano A" first="A M" last="Lozano">A M Lozano</name></author><author><name sortKey="Hamani, C" sort="Hamani, C" uniqKey="Hamani C" first="C" last="Hamani">C. Hamani</name></author></analytic><series><title level="j">Journal of neurosurgical sciences</title><idno type="ISSN">0390-5616</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Deep Brain Stimulation (methods)</term><term>Humans</term><term>Memory (physiology)</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (therapy)</term><term>Subthalamic Nucleus (physiopathology)</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Memory</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">As the population of many countries ages, disorders of cognition and memory-such as Alzheimer's Disease (AD) and dementia associated with Parkinson's Disease-will become a major societal burden. At present, few effective medical therapies against these conditions are available. Deep brain stimulation (DBS) may be a potential therapeutic option, because it can directly target and modulate the activity of structures implicated in circuits subserving memory function. In this article, we review the scientific literature to address some of the mechanisms by which DBS may impact memory and cognition. We then summarize the results of recent clinical experience with DBS in AD and Parkinsonian dementia.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Hamani, C" sort="Hamani, C" uniqKey="Hamani C" first="C" last="Hamani">C. Hamani</name><name sortKey="Lozano, A M" sort="Lozano, A M" uniqKey="Lozano A" first="A M" last="Lozano">A M Lozano</name><name sortKey="Sankar, T" sort="Sankar, T" uniqKey="Sankar T" first="T" last="Sankar">T. Sankar</name></noCountry><country name="Canada"><region name="Ontario"><name sortKey="Laxton, A W" sort="Laxton, A W" uniqKey="Laxton A" first="A W" last="Laxton">A W Laxton</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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