Botulinum toxin A as treatment for drooling saliva in PD.
Identifieur interne : 000069 ( Ncbi/Checkpoint ); précédent : 000068; suivant : 000070Botulinum toxin A as treatment for drooling saliva in PD.
Auteurs : P K Pal [Canada] ; D B Calne ; S. Calne ; J K TsuiSource :
- Neurology [ 0028-3878 ] ; 2000.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Botulinum Toxins, Type A (therapeutic use), Female, Humans, Injections, Male, Middle Aged, Parkinson Disease (complications), Parotid Gland (drug effects), Parotid Gland (secretion), Saliva (drug effects), Saliva (secretion), Sialorrhea (drug therapy), Sialorrhea (etiology), Treatment Outcome.
- MESH :
- chemical , therapeutic use : Botulinum Toxins, Type A.
- complications : Parkinson Disease.
- drug effects : Parotid Gland, Saliva.
- drug therapy : Sialorrhea.
- etiology : Sialorrhea.
- secretion : Parotid Gland, Saliva.
- Aged, Aged, 80 and over, Female, Humans, Injections, Male, Middle Aged, Treatment Outcome.
Abstract
The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease.
PubMed: 10636161
Affiliations:
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pubmed:10636161Le document en format XML
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Calne</name></author><author><name sortKey="Tsui, J K" sort="Tsui, J K" uniqKey="Tsui J" first="J K" last="Tsui">J K Tsui</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2000">2000</date><idno type="RBID">pubmed:10636161</idno><idno type="pmid">10636161</idno><idno type="wicri:Area/PubMed/Corpus">001667</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001667</idno><idno type="wicri:Area/PubMed/Curation">001667</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001667</idno><idno type="wicri:Area/PubMed/Checkpoint">001667</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001667</idno><idno type="wicri:Area/Ncbi/Merge">000069</idno><idno type="wicri:Area/Ncbi/Curation">000069</idno><idno type="wicri:Area/Ncbi/Checkpoint">000069</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Botulinum toxin A as treatment for drooling saliva in PD.</title><author><name sortKey="Pal, P K" sort="Pal, P K" uniqKey="Pal P" first="P K" last="Pal">P K Pal</name><affiliation wicri:level="1"><nlm:affiliation>Neurodegenerative Disorders Centre, UBC Hospital, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Neurodegenerative Disorders Centre, UBC Hospital, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Calne, D B" sort="Calne, D B" uniqKey="Calne D" first="D B" last="Calne">D B Calne</name></author><author><name sortKey="Calne, S" sort="Calne, S" uniqKey="Calne S" first="S" last="Calne">S. Calne</name></author><author><name sortKey="Tsui, J K" sort="Tsui, J K" uniqKey="Tsui J" first="J K" last="Tsui">J K Tsui</name></author></analytic><series><title level="j">Neurology</title><idno type="ISSN">0028-3878</idno><imprint><date when="2000" type="published">2000</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Botulinum Toxins, Type A (therapeutic use)</term><term>Female</term><term>Humans</term><term>Injections</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (complications)</term><term>Parotid Gland (drug effects)</term><term>Parotid Gland (secretion)</term><term>Saliva (drug effects)</term><term>Saliva (secretion)</term><term>Sialorrhea (drug therapy)</term><term>Sialorrhea (etiology)</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Botulinum Toxins, Type A</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Parotid Gland</term><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Sialorrhea</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Sialorrhea</term></keywords><keywords scheme="MESH" qualifier="secretion" xml:lang="en"><term>Parotid Gland</term><term>Saliva</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Injections</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Calne, D B" sort="Calne, D B" uniqKey="Calne D" first="D B" last="Calne">D B Calne</name><name sortKey="Calne, S" sort="Calne, S" uniqKey="Calne S" first="S" last="Calne">S. Calne</name><name sortKey="Tsui, J K" sort="Tsui, J K" uniqKey="Tsui J" first="J K" last="Tsui">J K Tsui</name></noCountry><country name="Canada"><noRegion><name sortKey="Pal, P K" sort="Pal, P K" uniqKey="Pal P" first="P K" last="Pal">P K Pal</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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