Frontal and parietal lobe dysfunction in depression: delayed alternation and tactile learning deficits.
Identifieur interne : 004867 ( Main/Merge ); précédent : 004866; suivant : 004868Frontal and parietal lobe dysfunction in depression: delayed alternation and tactile learning deficits.
Auteurs : M. Freedman [Canada]Source :
- Neuropsychologia [ 0028-3932 ] ; 1994.
English descriptors
- KwdEn :
- Aged, Alzheimer Disease (physiopathology), Depressive Disorder (etiology), Depressive Disorder (physiopathology), Diagnosis, Differential, Frontal Lobe (physiopathology), Humans, Learning Disorders (etiology), Middle Aged, Parietal Lobe (physiopathology), Parkinson Disease (physiopathology), Space Perception, Touch.
- MESH :
- etiology : Depressive Disorder, Learning Disorders.
- physiopathology : Alzheimer Disease, Depressive Disorder, Frontal Lobe, Parietal Lobe, Parkinson Disease.
- Aged, Diagnosis, Differential, Humans, Middle Aged, Space Perception, Touch.
Abstract
To evaluate frontal and parietal lobe involvement in depression, behavioral tests sensitive to damage in these regions were administered to depressed patients over age 50. Delayed alternation (DA), delayed response and object alternation were used to assess dorsolateral frontal and orbitofrontal function. Tactile learning problems (TOL and TRL) assessed parietal lobe integrity. Depressed patients were significantly impaired on DA, TOL and TRL, suggesting spatial memory (DA) and tactile learning deficits. The functional neuroanatomy underlying these deficits may share features with Parkinson's and Alzheimer's diseases.
PubMed: 7969863
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pubmed:7969863Le document en format XML
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