La maladie de Parkinson au Canada (serveur d'exploration)

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Oscillatory activity in the globus pallidus internus: comparison between Parkinson's disease and dystonia.

Identifieur interne : 001185 ( Main/Merge ); précédent : 001184; suivant : 001186

Oscillatory activity in the globus pallidus internus: comparison between Parkinson's disease and dystonia.

Auteurs : Moran Weinberger [Canada] ; William D. Hutchison ; Mahan Alavi ; Mojgan Hodaie ; Andres M. Lozano ; Elena Moro ; Jonathan O. Dostrovsky

Source :

RBID : pubmed:21843964

English descriptors

Abstract

Deep brain stimulation in the globus pallidus internus (GPi) is used to alleviate the motor symptoms of both Parkinson's disease (PD) and dystonia. We tested the hypothesis that PD and dystonia are characterized by different temporal patterns of synchronized oscillations in the GPi, and that the dopaminergic loss in PD makes the basal ganglia more susceptible to oscillatory activity.

DOI: 10.1016/j.clinph.2011.07.029
PubMed: 21843964

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pubmed:21843964

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