Globus pallidus dopamine and Parkinson motor subtypes: clinical and brain biochemical correlation.
Identifieur interne : 002189 ( Main/Exploration ); précédent : 002188; suivant : 002190Globus pallidus dopamine and Parkinson motor subtypes: clinical and brain biochemical correlation.
Auteurs : A H Rajput [Canada] ; H H Sitte ; A. Rajput ; M E Fenton ; C. Pifl ; O. HornykiewiczSource :
- Neurology [ 1526-632X ] ; 2008.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Brain Chemistry (physiology), Dopamine (metabolism), Female, Globus Pallidus (chemistry), Globus Pallidus (metabolism), Globus Pallidus (pathology), Humans, Male, Middle Aged, Motor Skills Disorders (classification), Motor Skills Disorders (metabolism), Motor Skills Disorders (pathology), Parkinson Disease (classification), Parkinson Disease (metabolism), Parkinson Disease (pathology).
- MESH :
- chemical , metabolism : Dopamine.
- chemistry : Globus Pallidus.
- classification : Motor Skills Disorders, Parkinson Disease.
- metabolism : Globus Pallidus, Motor Skills Disorders, Parkinson Disease.
- pathology : Globus Pallidus, Motor Skills Disorders, Parkinson Disease.
- physiology : Brain Chemistry.
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged.
Abstract
Patients with Parkinson disease (PD) may be akinetic/rigid, be tremor dominant, or have comparable severity of these motor symptoms (classic). The pathophysiologic basis of different PD phenotypes is unknown. This study assessed pallidal and striatal dopamine level patterns in different motor subgroups of PD and normal control brains.
DOI: 10.1212/01.wnl.0000285082.18969.3a
PubMed: 18172064
Affiliations:
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Le document en format XML
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Rajput</name></author><author><name sortKey="Fenton, M E" sort="Fenton, M E" uniqKey="Fenton M" first="M E" last="Fenton">M E Fenton</name></author><author><name sortKey="Pifl, C" sort="Pifl, C" uniqKey="Pifl C" first="C" last="Pifl">C. Pifl</name></author><author><name sortKey="Hornykiewicz, O" sort="Hornykiewicz, O" uniqKey="Hornykiewicz O" first="O" last="Hornykiewicz">O. 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Rajput</name></author><author><name sortKey="Fenton, M E" sort="Fenton, M E" uniqKey="Fenton M" first="M E" last="Fenton">M E Fenton</name></author><author><name sortKey="Pifl, C" sort="Pifl, C" uniqKey="Pifl C" first="C" last="Pifl">C. Pifl</name></author><author><name sortKey="Hornykiewicz, O" sort="Hornykiewicz, O" uniqKey="Hornykiewicz O" first="O" last="Hornykiewicz">O. Hornykiewicz</name></author></analytic><series><title level="j">Neurology</title><idno type="eISSN">1526-632X</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Brain Chemistry (physiology)</term><term>Dopamine (metabolism)</term><term>Female</term><term>Globus Pallidus (chemistry)</term><term>Globus Pallidus (metabolism)</term><term>Globus Pallidus (pathology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Motor Skills Disorders (classification)</term><term>Motor Skills Disorders (metabolism)</term><term>Motor Skills Disorders (pathology)</term><term>Parkinson Disease (classification)</term><term>Parkinson Disease (metabolism)</term><term>Parkinson Disease (pathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Dopamine</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Globus Pallidus</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Motor Skills Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Globus Pallidus</term><term>Motor Skills Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Globus Pallidus</term><term>Motor Skills Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Brain Chemistry</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Patients with Parkinson disease (PD) may be akinetic/rigid, be tremor dominant, or have comparable severity of these motor symptoms (classic). The pathophysiologic basis of different PD phenotypes is unknown. This study assessed pallidal and striatal dopamine level patterns in different motor subgroups of PD and normal control brains.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Fenton, M E" sort="Fenton, M E" uniqKey="Fenton M" first="M E" last="Fenton">M E Fenton</name><name sortKey="Hornykiewicz, O" sort="Hornykiewicz, O" uniqKey="Hornykiewicz O" first="O" last="Hornykiewicz">O. Hornykiewicz</name><name sortKey="Pifl, C" sort="Pifl, C" uniqKey="Pifl C" first="C" last="Pifl">C. Pifl</name><name sortKey="Rajput, A" sort="Rajput, A" uniqKey="Rajput A" first="A" last="Rajput">A. Rajput</name><name sortKey="Sitte, H H" sort="Sitte, H H" uniqKey="Sitte H" first="H H" last="Sitte">H H Sitte</name></noCountry><country name="Canada"><noRegion><name sortKey="Rajput, A H" sort="Rajput, A H" uniqKey="Rajput A" first="A H" last="Rajput">A H Rajput</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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