Neonatal enzymic development in the interpeduncular nucleus and surrounding ventral tegmentum
Identifieur interne : 005355 ( Main/Exploration ); précédent : 005354; suivant : 005356Neonatal enzymic development in the interpeduncular nucleus and surrounding ventral tegmentum
Auteurs : E. G. Mcgeer [Canada] ; J. Parkinson [Canada] ; P. L. Mcgeer [Canada]Source :
- Experimental Neurology [ 0014-4886 ] ; 1976.
Abstract
Choline acetyltransferase, tyrosine hydroxylase, glutamic acid decarboxylase, and acetylcholinesterase activities were measured in the combined interpeduncular nucleus and surrounding tegmentum in rats from 3 to 30 days of age. At 3 days choline acetyltransferase activity is 5% and glutamic acid decarboxylase activity is 24% of the activities at 30 days and both show significant linear correlations with age. Tyrosine hydroxylase and acetylcholinesterase at 3 days are each > 70% of the corresponding activity at 30 days and neither shows a significant linear correlation with age. Results are compared with similar data for rat neostriatum.
Url:
DOI: 10.1016/0014-4886(76)90286-7
Affiliations:
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<front><div type="abstract" xml:lang="en">Choline acetyltransferase, tyrosine hydroxylase, glutamic acid decarboxylase, and acetylcholinesterase activities were measured in the combined interpeduncular nucleus and surrounding tegmentum in rats from 3 to 30 days of age. At 3 days choline acetyltransferase activity is 5% and glutamic acid decarboxylase activity is 24% of the activities at 30 days and both show significant linear correlations with age. Tyrosine hydroxylase and acetylcholinesterase at 3 days are each > 70% of the corresponding activity at 30 days and neither shows a significant linear correlation with age. Results are compared with similar data for rat neostriatum.</div>
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