A dissociation between real and simulated movements in Parkinson's disease
Identifieur interne : 002D52 ( Main/Exploration ); précédent : 002D51; suivant : 002D53A dissociation between real and simulated movements in Parkinson's disease
Auteurs : Victor Frak [Canada] ; Henri Cohen [Canada] ; Emmanuelle Pourcher [Canada]Source :
- Neuroreport : (Oxford) [ 0959-4965 ] ; 2004.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- MESH :
- physiology : Imagination, Motor Activity, Movement.
- physiopathology : Parkinson Disease.
- Female, Hand Strength, Humans, Male, Middle Aged.
Abstract
Subcortical lesions have been simultaneously implicated in both real and simulated movement deficits. However, the analysis of the simulated opposition axis in precision grasping reveals that, in individuals with idiopathic bilateral Parkinson's disease motor imagery is impaired and that execution of overt movements is spared. This constitutes the first lesion observation congruent with the anatomical and functional dichotomy between real and simulated movements seen in experimental studies. These results underline the modality-specific nature of motor imagery and show that subcortical damage differentially impacts on motor activity.
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Subcortical lesions have been simultaneously implicated in both real and simulated movement deficits. However, the analysis of the simulated opposition axis in precision grasping reveals that, in individuals with idiopathic bilateral Parkinson's disease motor imagery is impaired and that execution of overt movements is spared. This constitutes the first lesion observation congruent with the anatomical and functional dichotomy between real and simulated movements seen in experimental studies. These results underline the modality-specific nature of motor imagery and show that subcortical damage differentially impacts on motor activity.</div>
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