ParkinsonCanadaV1, Main, Exploration, bibRecord, 000559

Recruitment strategies and patient selection in clinical trials for Parkinson's disease: Going viral and keeping science and ethics at the highest standards.

Identifieur interne : 000559 ( Main/Exploration ); précédent : 000558; suivant : 000560

Recruitment strategies and patient selection in clinical trials for Parkinson's disease: Going viral and keeping science and ethics at the highest standards.

Auteurs : Marina Picillo [Italie] ; Nancy Kou [Canada] ; Paolo Barone [Italie] ; Alfonso Fasano [Canada]

Source :

Parkinsonism & related disorders [ 1873-5126 ] ; 2015.

RBID : pubmed:26228079

English descriptors

KwdEn :
- Clinical Trials as Topic (ethics), Clinical Trials as Topic (standards), Humans, Internet (trends), Parkinson Disease (therapy), Patient Selection.
MESH :
- ethics : Clinical Trials as Topic.
- standards : Clinical Trials as Topic.
- therapy : Parkinson Disease.
- trends : Internet.
- Humans, Patient Selection.

Abstract

Enrollment of an adequate number of suitable candidates is a critical component of good quality randomized controlled trials (RCTs). Parkinson's disease (PD) is a highly heterogeneous disease and recruiting a large and homogeneous sample of patients is often challenging. Further, PD patients are often elderly, cognitively impaired and disabled, thus requiring the assistance from their caregivers for participation in RCTs. Only a limited number of studies have explored the effectiveness of recruitment strategies and PD patient selection in clinical trials. We aim to review the four crucial recruitment components of RCTs (i.e. infrastructure, nature of the research, recruiter characteristics and participant characteristics) with particular implications in PD, and to explore strategies to improve recruitment and patient selection in RCTs in PD.

DOI: 10.1016/j.parkreldis.2015.07.018
PubMed: 26228079

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Enrollment of an adequate number of suitable candidates is a critical component of good quality randomized controlled trials (RCTs). Parkinson's disease (PD) is a highly heterogeneous disease and recruiting a large and homogeneous sample of patients is often challenging. Further, PD patients are often elderly, cognitively impaired and disabled, thus requiring the assistance from their caregivers for participation in RCTs. Only a limited number of studies have explored the effectiveness of recruitment strategies and PD patient selection in clinical trials. We aim to review the four crucial recruitment components of RCTs (i.e. infrastructure, nature of the research, recruiter characteristics and participant characteristics) with particular implications in PD, and to explore strategies to improve recruitment and patient selection in RCTs in PD.</div>
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La maladie de Parkinson au Canada (serveur d'exploration)

Recruitment strategies and patient selection in clinical trials for Parkinson's disease: Going viral and keeping science and ethics at the highest standards.

Recruitment strategies and patient selection in clinical trials for Parkinson's disease: Going viral and keeping science and ethics at the highest standards.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.