Movement disorders.
Identifieur interne : 000278 ( Main/Exploration ); précédent : 000277; suivant : 000279Movement disorders.
Auteurs : A Jon Stoessl [Canada] ; Martin J. Mckeown [Canada]Source :
- Handbook of clinical neurology [ 0072-9752 ] ; 2016.
English descriptors
- KwdEn :
- MESH :
- classification : Movement Disorders, Neuroimaging.
- diagnostic imaging : Movement Disorders.
- methods : Neuroimaging.
- Humans, Image Processing, Computer-Assisted.
Abstract
Movement disorders can be hypokinetic (e.g., parkinsonism), hyperkinetic, or dystonic in nature and commonly arise from altered function in nuclei of the basal ganglia or their connections. As obvious structural changes are often limited, standard imaging plays less of a role than in other neurologic disorders. However, structural imaging is indicated where clinical presentation is atypical, particularly if the disorder is abrupt in onset or remains strictly unilateral. More recent advances in magnetic resonance imaging (MRI) may allow for differentiation between Parkinson's disease and atypical forms of parkinsonism. Functional imaging can assess regional cerebral blood flow (functional MRI (fMRI), positron emission tomography (PET), or single-photon emission computed tomography (SPECT)), cerebral glucose metabolism (PET), neurochemical and neuroreceptor status (PET and SPECT), and pathologic processes such as inflammation or abnormal protein deposition (PET) (Table 49.1). Cerebral blood flow can be assessed at rest, during the performance of motor or cognitive tasks, or in response to a variety of stimuli. In appropriate situations, the correct imaging modality and/or combination of modalities can be used to detect early disease or even preclinical disease, and to monitor disease progression and the effects of disease-modifying interventions. Various approaches are reviewed here.
DOI: 10.1016/B978-0-444-53486-6.00049-1
PubMed: 27430452
Affiliations:
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Le document en format XML
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Mckeown</name><affiliation wicri:level="1"><nlm:affiliation>Pacific Parkinson's Research Centre and Division of Neurology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia and Vancouver Coastal Health, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Pacific Parkinson's Research Centre and Division of Neurology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia and Vancouver Coastal Health, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27430452</idno><idno type="pmid">27430452</idno><idno type="doi">10.1016/B978-0-444-53486-6.00049-1</idno><idno type="wicri:Area/PubMed/Corpus">000326</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000326</idno><idno type="wicri:Area/PubMed/Curation">000326</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000326</idno><idno type="wicri:Area/PubMed/Checkpoint">000326</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000326</idno><idno type="wicri:Area/Ncbi/Merge">002031</idno><idno type="wicri:Area/Ncbi/Curation">002031</idno><idno type="wicri:Area/Ncbi/Checkpoint">002031</idno><idno type="wicri:Area/Main/Merge">000279</idno><idno type="wicri:Area/Main/Curation">000278</idno><idno type="wicri:Area/Main/Exploration">000278</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Movement disorders.</title><author><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A Jon" last="Stoessl">A Jon Stoessl</name><affiliation wicri:level="1"><nlm:affiliation>Pacific Parkinson's Research Centre and Division of Neurology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia and Vancouver Coastal Health, Vancouver, BC, Canada. Electronic address: jstoessl@mail.ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Pacific Parkinson's Research Centre and Division of Neurology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia and Vancouver Coastal Health, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Mckeown, Martin J" sort="Mckeown, Martin J" uniqKey="Mckeown M" first="Martin J" last="Mckeown">Martin J. Mckeown</name><affiliation wicri:level="1"><nlm:affiliation>Pacific Parkinson's Research Centre and Division of Neurology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia and Vancouver Coastal Health, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Pacific Parkinson's Research Centre and Division of Neurology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia and Vancouver Coastal Health, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author></analytic><series><title level="j">Handbook of clinical neurology</title><idno type="ISSN">0072-9752</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Movement Disorders (classification)</term><term>Movement Disorders (diagnostic imaging)</term><term>Neuroimaging (classification)</term><term>Neuroimaging (methods)</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Movement Disorders</term><term>Neuroimaging</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Movement Disorders</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Neuroimaging</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Image Processing, Computer-Assisted</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Movement disorders can be hypokinetic (e.g., parkinsonism), hyperkinetic, or dystonic in nature and commonly arise from altered function in nuclei of the basal ganglia or their connections. As obvious structural changes are often limited, standard imaging plays less of a role than in other neurologic disorders. However, structural imaging is indicated where clinical presentation is atypical, particularly if the disorder is abrupt in onset or remains strictly unilateral. More recent advances in magnetic resonance imaging (MRI) may allow for differentiation between Parkinson's disease and atypical forms of parkinsonism. Functional imaging can assess regional cerebral blood flow (functional MRI (fMRI), positron emission tomography (PET), or single-photon emission computed tomography (SPECT)), cerebral glucose metabolism (PET), neurochemical and neuroreceptor status (PET and SPECT), and pathologic processes such as inflammation or abnormal protein deposition (PET) (Table 49.1). Cerebral blood flow can be assessed at rest, during the performance of motor or cognitive tasks, or in response to a variety of stimuli. In appropriate situations, the correct imaging modality and/or combination of modalities can be used to detect early disease or even preclinical disease, and to monitor disease progression and the effects of disease-modifying interventions. Various approaches are reviewed here.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A Jon" last="Stoessl">A Jon Stoessl</name></noRegion><name sortKey="Mckeown, Martin J" sort="Mckeown, Martin J" uniqKey="Mckeown M" first="Martin J" last="Mckeown">Martin J. Mckeown</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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