A randomized, controlled, multicentre trial comparing pegvisomant alone with combination therapy of pegvisomant and long‐acting octreotide in patients with acromegaly
Identifieur interne : 002048 ( Main/Curation ); précédent : 002047; suivant : 002049A randomized, controlled, multicentre trial comparing pegvisomant alone with combination therapy of pegvisomant and long‐acting octreotide in patients with acromegaly
Auteurs : Peter J. Trainer [Royaume-Uni] ; Shereen Ezzat [Canada] ; Gwyn A. D Ouza [Royaume-Uni] ; Gary Layton [Royaume-Uni] ; Christian J. Strasburger [Allemagne]Source :
- Clinical Endocrinology [ 0300-0664 ] ; 2009-10.
Abstract
Objective For patients with acromegaly who are suboptimally controlled on long‐acting octreotide (LAR), treatment options are to switch to pegvisomant monotherapy (PM) or add pegvisomant to LAR (P‐LAR). Our objective was to evaluate if the safety and efficacy of these regimens differ.
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DOI: 10.1111/j.1365-2265.2009.03620.x
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<front><div type="abstract">Objective For patients with acromegaly who are suboptimally controlled on long‐acting octreotide (LAR), treatment options are to switch to pegvisomant monotherapy (PM) or add pegvisomant to LAR (P‐LAR). Our objective was to evaluate if the safety and efficacy of these regimens differ.</div>
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