Human herpes virus 6 and multiple sclerosis
Identifieur interne : 001857 ( Istex/Curation ); précédent : 001856; suivant : 001858Human herpes virus 6 and multiple sclerosis
Auteurs : F. G. A. Moore ; C. Wolfson [Canada]Source :
- Acta Neurologica Scandinavica [ 0001-6314 ] ; 2002-08.
English descriptors
Abstract
Objectives – To systematically review the published evidence for a relationship between human herpes virus 6 (HHV‐6) and multiple sclerosis (MS). Materials and methods – The medical literature was searched using MEDLINE and the Cochrane database. Retrieved studies are presented according to the experimental technique(s) used. The studies are rated for quality using a priori defined criteria. Results – Twenty‐eight studies were retrieved. A total of 12 different experimental techniques were used. Four of these techniques provided evidence for a relationship between HHV‐6 and MS, but none were able to show a causative relationship. Conclusions – The available literature provides some support for a relationship between HHV‐6 and MS. The limitations of the available studies and directions for future research are discussed.
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DOI: 10.1034/j.1600-0404.2002.01251.x
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F. G. A. Moore<affiliation><mods:affiliation>Department of Neurology, McGill University, Montreal, Quebec, Canada,</mods:affiliation>
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Objectives – To systematically review the published evidence for a relationship between human herpes virus 6 (HHV‐6) and multiple sclerosis (MS). Materials and methods – The medical literature was searched using MEDLINE and the Cochrane database. Retrieved studies are presented according to the experimental technique(s) used. The studies are rated for quality using a priori defined criteria. Results – Twenty‐eight studies were retrieved. A total of 12 different experimental techniques were used. Four of these techniques provided evidence for a relationship between HHV‐6 and MS, but none were able to show a causative relationship. Conclusions – The available literature provides some support for a relationship between HHV‐6 and MS. The limitations of the available studies and directions for future research are discussed.</div>
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