Neurodegenerative diseases and risk factors: A literature review
Identifieur interne : 001140 ( Istex/Corpus ); précédent : 001139; suivant : 001141Neurodegenerative diseases and risk factors: A literature review
Auteurs : Jean-François Emard ; Jean-Pierre Thouez ; Denis GauvreauSource :
- Social Science & Medicine [ 0277-9536 ] ; 1995.
Abstract
Degenerative diseases of the central nervous system are significant causes of mortality among elderly people in industrialized countries. For the most part, the causes of these diseases are unknown. It is also very difficult to diagnose this type of disease quickly and accurately. This article reviews the epidemiological research on the principal neurodegenerative disorders, focusing on geographical, hereditary and viral and toxicological exposure correlates. We look in particular at the effect of exposure to toxins as well as the effect that deficiencies of elements such as calcium and selenium could have on the development of these neurological diseases. We also consider the possible protectionist effect of some variables on the development of certain neurological diseases.
Url:
DOI: 10.1016/0277-9536(94)00138-J
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Il est, en outre, difficile de diagnostiquer plusieurs de ces affections de façon rapide et précise. Cet article fait la revue de la littérature en ce qui concerne la recherche épidémiologique sur les principaux désordres neurodégénératifs, notamment sur l'épidémiologie géographique, l'hérédité, ainsi que sur les questions relatives à l'exposition du type viral et toxique. Nous nous interrogeons sur les effets d'une exposition à certaines toxines ou d'une exposition à des concentrations déficitaires d'éléments comme le calcium et le sélénium dans le risque de développer un désordre du type neurodégénératif. Nous nous interrogeons également sur les effets protectionistes possibles de certains éléments dans le risque d'atteinte d'une maladie neurodégénérative.</p></abstract><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>neurodegenerative diseases</term></item><item><term>epidemiology</term></item><item><term>Alzheimer's disease</term></item><item><term>risk factors</term></item><item><term>environment</term></item></list></keywords></textClass><textClass xml:lang="fr"><keywords scheme="keyword"><list><head>Mots-clé</head><item><term>maladies neurodégénératives</term></item><item><term>épidémiologie</term></item><item><term>maladie d'Alzheimer</term></item><item><term>facteurs de risque</term></item><item><term>environnement</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1995">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api-v5.istex.fr/document/87D03FA850AEE413A4CEB07DC03DD8AAFDA3280E/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>SSM</jid><aid>9400138J</aid><ce:pii>0277-9536(94)00138-J</ce:pii><ce:doi>10.1016/0277-9536(94)00138-J</ce:doi><ce:copyright type="unknown" year="1995"></ce:copyright></item-info><head><ce:title>Neurodegenerative diseases and risk factors: A literature review</ce:title><ce:author-group><ce:author><ce:given-name>Jean-François</ce:given-name><ce:surname>Emard</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Jean-Pierre</ce:given-name><ce:surname>Thouez</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Denis</ce:given-name><ce:surname>Gauvreau</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>1</ce:label><ce:textfn>Projet IMAGE, Centre Hospitalier Côte-des-Neiges, 4565, chemin de la Reine-Marie, Montréal, Québec, Canada H3W 1W5</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>2</ce:label><ce:textfn>Département de Géographie, Université de Montréal, C.P. 6128, Succursale A Montréal, Québec, Canada H3C 3J7</ce:textfn></ce:affiliation></ce:author-group><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Degenerative diseases of the central nervous system are significant causes of mortality among elderly people in industrialized countries. For the most part, the causes of these diseases are unknown. It is also very difficult to diagnose this type of disease quickly and accurately. This article reviews the epidemiological research on the principal neurodegenerative disorders, focusing on geographical, hereditary and viral and toxicological exposure correlates. We look in particular at the effect of exposure to toxins as well as the effect that deficiencies of elements such as calcium and selenium could have on the development of these neurological diseases. We also consider the possible protectionist effect of some variables on the development of certain neurological diseases.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:abstract xml:lang="fr"><ce:section-title>Résumé</ce:section-title><ce:abstract-sec><ce:simple-para>Les maladies dégénératives du système nerveux central sont reconnues comme une cause de mortalité importante chez les personnes âgées des pays industrialisés. Les causes de ces maladies demeurent, pour la plupart, encore inconnues. Il est, en outre, difficile de diagnostiquer plusieurs de ces affections de façon rapide et précise. Cet article fait la revue de la littérature en ce qui concerne la recherche épidémiologique sur les principaux désordres neurodégénératifs, notamment sur l'épidémiologie géographique, l'hérédité, ainsi que sur les questions relatives à l'exposition du type viral et toxique. Nous nous interrogeons sur les effets d'une exposition à certaines toxines ou d'une exposition à des concentrations déficitaires d'éléments comme le calcium et le sélénium dans le risque de développer un désordre du type neurodégénératif. Nous nous interrogeons également sur les effets protectionistes possibles de certains éléments dans le risque d'atteinte d'une maladie neurodégénérative.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>neurodegenerative diseases</ce:text></ce:keyword><ce:keyword><ce:text>epidemiology</ce:text></ce:keyword><ce:keyword><ce:text>Alzheimer's disease</ce:text></ce:keyword><ce:keyword><ce:text>risk factors</ce:text></ce:keyword><ce:keyword><ce:text>environment</ce:text></ce:keyword></ce:keywords><ce:keywords xml:lang="fr"><ce:section-title>Mots-clé</ce:section-title><ce:keyword><ce:text>maladies neurodégénératives</ce:text></ce:keyword><ce:keyword><ce:text>épidémiologie</ce:text></ce:keyword><ce:keyword><ce:text>maladie d'Alzheimer</ce:text></ce:keyword><ce:keyword><ce:text>facteurs de risque</ce:text></ce:keyword><ce:keyword><ce:text>environnement</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Neurodegenerative diseases and risk factors: A literature review</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Neurodegenerative diseases and risk factors: A literature review</title></titleInfo><name type="personal"><namePart type="given">Jean-François</namePart><namePart type="family">Emard</namePart><affiliation>Projet IMAGE, Centre Hospitalier Côte-des-Neiges, 4565, chemin de la Reine-Marie, Montréal, Québec, Canada H3W 1W5</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jean-Pierre</namePart><namePart type="family">Thouez</namePart><affiliation>Département de Géographie, Université de Montréal, C.P. 6128, Succursale A Montréal, Québec, Canada H3C 3J7</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Denis</namePart><namePart type="family">Gauvreau</namePart><affiliation>Projet IMAGE, Centre Hospitalier Côte-des-Neiges, 4565, chemin de la Reine-Marie, Montréal, Québec, Canada H3W 1W5</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1995</dateIssued><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Degenerative diseases of the central nervous system are significant causes of mortality among elderly people in industrialized countries. 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Il est, en outre, difficile de diagnostiquer plusieurs de ces affections de façon rapide et précise. Cet article fait la revue de la littérature en ce qui concerne la recherche épidémiologique sur les principaux désordres neurodégénératifs, notamment sur l'épidémiologie géographique, l'hérédité, ainsi que sur les questions relatives à l'exposition du type viral et toxique. Nous nous interrogeons sur les effets d'une exposition à certaines toxines ou d'une exposition à des concentrations déficitaires d'éléments comme le calcium et le sélénium dans le risque de développer un désordre du type neurodégénératif. 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