La maladie de Parkinson au Canada (serveur d'exploration)

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Deep brain stimulation: Neuropsychological and neuropsychiatric issues

Identifieur interne : 001135 ( Istex/Corpus ); précédent : 001134; suivant : 001136

Deep brain stimulation: Neuropsychological and neuropsychiatric issues

Auteurs : Valerie Voon ; Cynthia Kubu ; Paul Krack ; Jean-Luc Houeto ; Alexander I. Tröster

Source :

RBID : ISTEX:7E8B648429424846CEF91F3874527BDBFE1C265F

English descriptors

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor, cognitive, neuropsychiatric, autonomic, and other nonmotor symptoms. The efficacy of deep brain stimulation (DBS) for the motor symptoms of advanced PD is well established. However, the effects of DBS on the cognitive and neuropsychiatric symptoms are less clear. The neuropsychiatric aspects of DBS for PD have recently been of considerable clinical and pathophysiological interest. As a companion to the preoperative and postoperative sections of the DBS consensus articles, this article reviews the published literature on the cognitive and neuropsychiatric aspects of DBS for PD. The majority of the observed neuropsychiatric symptoms are transient, treatable, and potentially preventable. Outcome studies, methodological issues, pathophysiology, and preoperative and postoperative management of the cognitive and neuropsychiatric aspects and complications of DBS for PD are discussed. © 2006 Movement Disorder Society

Url:
DOI: 10.1002/mds.20963

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ISTEX:7E8B648429424846CEF91F3874527BDBFE1C265F

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<abstract lang="en">Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor, cognitive, neuropsychiatric, autonomic, and other nonmotor symptoms. The efficacy of deep brain stimulation (DBS) for the motor symptoms of advanced PD is well established. However, the effects of DBS on the cognitive and neuropsychiatric symptoms are less clear. The neuropsychiatric aspects of DBS for PD have recently been of considerable clinical and pathophysiological interest. As a companion to the preoperative and postoperative sections of the DBS consensus articles, this article reviews the published literature on the cognitive and neuropsychiatric aspects of DBS for PD. The majority of the observed neuropsychiatric symptoms are transient, treatable, and potentially preventable. Outcome studies, methodological issues, pathophysiology, and preoperative and postoperative management of the cognitive and neuropsychiatric aspects and complications of DBS for PD are discussed. © 2006 Movement Disorder Society</abstract>
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<identifier type="ISSN">0885-3185</identifier>
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<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
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<date>2006</date>
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