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Heat recovery ventilators prevent respiratory disorders in Inuit children

Identifieur interne : 000F50 ( Istex/Corpus ); précédent : 000F49; suivant : 000F51

Heat recovery ventilators prevent respiratory disorders in Inuit children

Auteurs : T. Kovesi ; C. Zaloum ; C. Stocco ; D. Fugler ; R. E. Dales ; A. Ni ; N. Barrowman ; N. L. Gilbert ; J. D. Miller

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RBID : ISTEX:908CAC060283F717AAF081D3B84432194F1834AD

English descriptors

Abstract

Abstract  Inuit infants have high rates of reported hospitalization for respiratory infection, associated with overcrowding and reduced ventilation. We performed a randomized, double‐blind, placebo controlled trial to determine whether home heat recovery ventilators (HRV) would improve ventilation and reduce the risk of respiratory illnesses in young Inuit children. Inuit children under 6 years of age living in several communities in Nunavut, Canada were randomized to receive an active or placebo HRV. We monitored respiratory symptoms, health center encounters, and indoor air quality for 6 months. HRVs were placed in 68 homes, and 51 houses could be analyzed. Subjects had a mean age of 26.8 months. Active HRVs brought indoor carbon dioxide concentrations to within recommended concentrations. Relative humidity was also reduced. Use of HRV, compared with placebo, was associated with a progressive fall in the odds ratio for reported wheeze of 12.3% per week (95%CI 1.9–21.6%, P = 0.022). Rates of reported rhinitis were significantly lower in the HRV group than the placebo group in month 1 (odds ratio 0.20, 95%CI 0.058–0.69, P = 0.011) and in month 4 (odds ratio 0.24, 95%CI 0.054–0.90, P = 0.035). There were no significant reductions in the number of health center encounters, and there were no hospitalizations. Use of HRVs was associated with in improvement in air quality and reductions in reported respiratory symptoms in Inuit children.

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DOI: 10.1111/j.1600-0668.2009.00615.x

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ISTEX:908CAC060283F717AAF081D3B84432194F1834AD

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<div type="abstract">Abstract  Inuit infants have high rates of reported hospitalization for respiratory infection, associated with overcrowding and reduced ventilation. We performed a randomized, double‐blind, placebo controlled trial to determine whether home heat recovery ventilators (HRV) would improve ventilation and reduce the risk of respiratory illnesses in young Inuit children. Inuit children under 6 years of age living in several communities in Nunavut, Canada were randomized to receive an active or placebo HRV. We monitored respiratory symptoms, health center encounters, and indoor air quality for 6 months. HRVs were placed in 68 homes, and 51 houses could be analyzed. Subjects had a mean age of 26.8 months. Active HRVs brought indoor carbon dioxide concentrations to within recommended concentrations. Relative humidity was also reduced. Use of HRV, compared with placebo, was associated with a progressive fall in the odds ratio for reported wheeze of 12.3% per week (95%CI 1.9–21.6%, P = 0.022). Rates of reported rhinitis were significantly lower in the HRV group than the placebo group in month 1 (odds ratio 0.20, 95%CI 0.058–0.69, P = 0.011) and in month 4 (odds ratio 0.24, 95%CI 0.054–0.90, P = 0.035). There were no significant reductions in the number of health center encounters, and there were no hospitalizations. Use of HRVs was associated with in improvement in air quality and reductions in reported respiratory symptoms in Inuit children.</div>
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<p>Abstract  Inuit infants have high rates of reported hospitalization for respiratory infection, associated with overcrowding and reduced ventilation. We performed a randomized, double‐blind, placebo controlled trial to determine whether home heat recovery ventilators (HRV) would improve ventilation and reduce the risk of respiratory illnesses in young Inuit children. Inuit children under 6 years of age living in several communities in Nunavut, Canada were randomized to receive an active or placebo HRV. We monitored respiratory symptoms, health center encounters, and indoor air quality for 6 months. HRVs were placed in 68 homes, and 51 houses could be analyzed. Subjects had a mean age of 26.8 months. Active HRVs brought indoor carbon dioxide concentrations to within recommended concentrations. Relative humidity was also reduced. Use of HRV, compared with placebo, was associated with a progressive fall in the odds ratio for reported wheeze of 12.3% per week (95%CI 1.9–21.6%, P = 0.022). Rates of reported rhinitis were significantly lower in the HRV group than the placebo group in month 1 (odds ratio 0.20, 95%CI 0.058–0.69, P = 0.011) and in month 4 (odds ratio 0.24, 95%CI 0.054–0.90, P = 0.035). There were no significant reductions in the number of health center encounters, and there were no hospitalizations. Use of HRVs was associated with in improvement in air quality and reductions in reported respiratory symptoms in Inuit children.</p>
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<p>Reduced ventilation is common in the houses of Inuit children in arctic Canada, and is associated with an increased risk of respiratory infection. Installation of HRV brings indoor carbon dioxide concentration, as a marker of adequate ventilation, to within recommended concentrations, although relative humidity is also reduced. Installation of HRV is associated with improvements in indoor air quality, and a reduced risk of wheezing and rhinitis not associated with cold air exposure in young Inuit children. Further research is required to explore traditional Inuit cultural attitudes about air movement in dwellings.</p>
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<title type="main" sort="INDOOR AIR">Indoor Air</title>
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<copyright>© 2009 John Wiley & Sons A/S</copyright>
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<correspondenceTo>T. Kovesi
Paediatric Respirologist
Children’s Hospital of Eastern Ontario
401 Smyth Rd.
Ottawa, ON K1H 8L1
Canada
Tel.: 613‐737‐7600 ext. 2868
Fax: 613‐738‐4886
e‐mail:
<email>kovesi@cheo.on.ca</email>
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<unparsedEditorialHistory>Received for review 20 February 2009. Accepted for publication 27 June 2009.</unparsedEditorialHistory>
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<title type="main">Heat recovery ventilators prevent respiratory disorders in Inuit children</title>
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<b>Kovesi et al.</b>
</title>
<title type="short">
<b>Nunavut heat recovery ventilator trial</b>
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<personName>
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<unparsedAffiliation>Air Health Effects Division, Health Canada, Ottawa, ON, Canada</unparsedAffiliation>
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<unparsedAffiliation>Policy and Research, Canada Mortgage and Housing Corporation, Ottawa, ON, Canada</unparsedAffiliation>
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<unparsedAffiliation>Department of Medicine, Ottawa Hospital, Ottawa, ON, Canada</unparsedAffiliation>
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<unparsedAffiliation>Biostatistics and Epidemiology Division, Health Canada, Ottawa, ON, Canada</unparsedAffiliation>
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<unparsedAffiliation>Department of Chemistry, Carleton University, Ottawa, ON, Canada</unparsedAffiliation>
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<keyword xml:id="k1">Respiratory Tract Infections</keyword>
<keyword xml:id="k2">Ventilation</keyword>
<keyword xml:id="k3">Child</keyword>
<keyword xml:id="k4">Preschool</keyword>
<keyword xml:id="k5">Inuits</keyword>
<keyword xml:id="k6">Wheezing</keyword>
<keyword xml:id="k7">Bronchiolitis</keyword>
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<p>
<b>Abstract </b>
Inuit infants have high rates of reported hospitalization for respiratory infection, associated with overcrowding and reduced ventilation. We performed a randomized, double‐blind, placebo controlled trial to determine whether home heat recovery ventilators (HRV) would improve ventilation and reduce the risk of respiratory illnesses in young Inuit children. Inuit children under 6 years of age living in several communities in Nunavut, Canada were randomized to receive an active or placebo HRV. We monitored respiratory symptoms, health center encounters, and indoor air quality for 6 months. HRVs were placed in 68 homes, and 51 houses could be analyzed. Subjects had a mean age of 26.8 months. Active HRVs brought indoor carbon dioxide concentrations to within recommended concentrations. Relative humidity was also reduced. Use of HRV, compared with placebo, was associated with a progressive fall in the odds ratio for reported wheeze of 12.3% per week (95%CI 1.9–21.6%,
<i>P </i>
= 0.022). Rates of reported rhinitis were significantly lower in the HRV group than the placebo group in month 1 (odds ratio 0.20, 95%CI 0.058–0.69,
<i>P </i>
= 0.011) and in month 4 (odds ratio 0.24, 95%CI 0.054–0.90,
<i>P </i>
= 0.035). There were no significant reductions in the number of health center encounters, and there were no hospitalizations. Use of HRVs was associated with in improvement in air quality and reductions in reported respiratory symptoms in Inuit children.</p>
</section>
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<title type="main">Practical Implications</title>
<p>Reduced ventilation is common in the houses of Inuit children in arctic Canada, and is associated with an increased risk of respiratory infection. Installation of HRV brings indoor carbon dioxide concentration, as a marker of adequate ventilation, to within recommended concentrations, although relative humidity is also reduced. Installation of HRV is associated with improvements in indoor air quality, and a reduced risk of wheezing and rhinitis not associated with cold air exposure in young Inuit children. Further research is required to explore traditional Inuit cultural attitudes about air movement in dwellings.</p>
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<namePart type="family">Stocco</namePart>
<affiliation>Air Health Effects Division, Health Canada, Ottawa, ON, Canada</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">D.</namePart>
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<abstract>Abstract  Inuit infants have high rates of reported hospitalization for respiratory infection, associated with overcrowding and reduced ventilation. We performed a randomized, double‐blind, placebo controlled trial to determine whether home heat recovery ventilators (HRV) would improve ventilation and reduce the risk of respiratory illnesses in young Inuit children. Inuit children under 6 years of age living in several communities in Nunavut, Canada were randomized to receive an active or placebo HRV. We monitored respiratory symptoms, health center encounters, and indoor air quality for 6 months. HRVs were placed in 68 homes, and 51 houses could be analyzed. Subjects had a mean age of 26.8 months. Active HRVs brought indoor carbon dioxide concentrations to within recommended concentrations. Relative humidity was also reduced. Use of HRV, compared with placebo, was associated with a progressive fall in the odds ratio for reported wheeze of 12.3% per week (95%CI 1.9–21.6%, P = 0.022). Rates of reported rhinitis were significantly lower in the HRV group than the placebo group in month 1 (odds ratio 0.20, 95%CI 0.058–0.69, P = 0.011) and in month 4 (odds ratio 0.24, 95%CI 0.054–0.90, P = 0.035). There were no significant reductions in the number of health center encounters, and there were no hospitalizations. Use of HRVs was associated with in improvement in air quality and reductions in reported respiratory symptoms in Inuit children.</abstract>
<abstract>Reduced ventilation is common in the houses of Inuit children in arctic Canada, and is associated with an increased risk of respiratory infection. Installation of HRV brings indoor carbon dioxide concentration, as a marker of adequate ventilation, to within recommended concentrations, although relative humidity is also reduced. Installation of HRV is associated with improvements in indoor air quality, and a reduced risk of wheezing and rhinitis not associated with cold air exposure in young Inuit children. Further research is required to explore traditional Inuit cultural attitudes about air movement in dwellings.</abstract>
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<topic>Respiratory Tract Infections</topic>
<topic>Ventilation</topic>
<topic>Child</topic>
<topic>Preschool</topic>
<topic>Inuits</topic>
<topic>Wheezing</topic>
<topic>Bronchiolitis</topic>
<topic>Pneumonia</topic>
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