Neural and neuroendocrine functions of dopamine
Identifieur interne : 002937 ( Istex/Checkpoint ); précédent : 002936; suivant : 002938Neural and neuroendocrine functions of dopamine
Auteurs : T. L. Sourkes [Canada]Source :
- Psychoneuroendocrinology [ 0306-4530 ] ; 1975.
Abstract
1. The functions of dopamine (3-hydroxytyramine) in the central nervous system are described. 2. The best understood of these is in relation to the extrapyramidal system. The example of striatal function is adduced on the bases of (a) the high concentration of dopamine in that structure and (b) presence of this amine in the terminations of fibres originating in the substantia nigra. 3. Dopamine-containing fibres with terminals in the hypothalamus play a role in regulating secretion of growth hormone releasing factor and, perhaps, others. Other monoamines seem to be similarly related to other releasing factors (RFs). 4. Our new understanding of the neurochemistry of the monoamines has aided in clarifying the neural pathways that regulate the anterior pituitary gland.
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DOI: 10.1016/0306-4530(75)90024-4
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