PROMOTING ACCESS TO INNOVATION FOR FRAIL OLD PERSONS: IAGG (INTERNATIONAL ASSOCIATION OF GERONTOLOGY AND GERIATRICS), WHO (WORLD HEALTH ORGANIZATION) AND SFGG (SOCIETE FRANCAISE DE GERIATRIE ET DE GERONTOLOGIE) WORKSHOP - ATHENS JANUARY 20-21, 2012
Identifieur interne : 000399 ( Main/Exploration ); précédent : 000398; suivant : 000400PROMOTING ACCESS TO INNOVATION FOR FRAIL OLD PERSONS: IAGG (INTERNATIONAL ASSOCIATION OF GERONTOLOGY AND GERIATRICS), WHO (WORLD HEALTH ORGANIZATION) AND SFGG (SOCIETE FRANCAISE DE GERIATRIE ET DE GERONTOLOGIE) WORKSHOP - ATHENS JANUARY 20-21, 2012
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Abstract
Frailty tends to be considered as a major risk for adverse outcomes in older persons, but some important aspects remain matter of debate. Objectives: The purpose of this paper is to present expert's positions on the main aspects of the frailty syndrome in the older persons. Participants: Workshop organized by International Association of Gerontology and Geriatrics (IAGG), World Health Organization (WHO) and Société Française de Gériatrie et de Gérontologie (SFGG). Results: Frailty is widely recognized as an important risk factor for adverse health outcomes in older persons. This can be of particular value in evaluating non-disabled older persons with chronic diseases but today no operational definition has been established. Nutritional status, mobility, activity, strength, endurance, cognition, and mood have been proposed as markers of frailty. Another approach calculates a multidimensional score ranging from "very fit" to "severely frail," but it is difficult to apply into the medical practice. Frailty appears to be secondary to multiple conditions using multiple pathways leading to a vulnerability to a stressor. Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.), as well as social factors (isolation, financial situation) are involved in the vulnerability process. In clinical practice, detection of frailty is of major interest in oncology because of the high prevalence of cancer in older persons and the bad tolerance of the drug therapies. Presence of frailty should also be taken into account in the definition of the cardiovascular risks in the older population. The experts of the workshop have listed the points reached an agreement and those must to be a priority for improving understanding and use of frailty syndrome in practice. Conclusion: Frailty in older adults is a syndrome corresponding to a vulnerability to a stressor. Diagnostic tools have been developed but none can integrate at the same time the large spectrum of factors and the simplicity asked by the clinical practice. An agreement with an international common definition is necessary to develop screening and to reduce the morbidity in older persons.
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">PROMOTING ACCESS TO INNOVATION FOR FRAIL OLD PERSONS: IAGG (INTERNATIONAL ASSOCIATION OF GERONTOLOGY AND GERIATRICS), WHO (WORLD HEALTH ORGANIZATION) AND SFGG (SOCIETE FRANCAISE DE GERIATRIE ET DE GERONTOLOGIE) WORKSHOP - ATHENS JANUARY 20-21, 2012</title><author><name sortKey="Berrut, G" uniqKey="Berrut G">G. Berrut</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Pôle Hospitalo-Universitaire de Gérontologie Clinique, CHU Nantes</s1><s2>Nantes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Andrieu, S" uniqKey="Andrieu S">S. Andrieu</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Gérontopole, Service de Santé Publique, CHU de Toulouse</s1><s3>FRA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>CHU de Toulouse</wicri:noRegion><wicri:noRegion>Gérontopole, Service de Santé Publique, CHU de Toulouse</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM 1027</s1><s2>Toulouse</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ><sZ>34 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="De Carvalho, I Araujo" uniqKey="De Carvalho I">I. Araujo De Carvalho</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Gender, Women and Health, World Health Organization (WHO)</s1><s2>Geneva</s2><s3>CHE</s3><sZ>3 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Baeyens, J P" uniqKey="Baeyens J">J. P. Baeyens</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Geriatric Medicine, Damiaan General Hospital</s1><s2>Ostend</s2><s3>BEL</s3><sZ>4 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Ostend</wicri:noRegion></affiliation></author><author><name sortKey="Bergman, H" uniqKey="Bergman H">H. Bergman</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Department of Family Medicine, Mc Gill University</s1><s2>Montreal</s2><s3>CAN</s3><sZ>5 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Cassim, B" uniqKey="Cassim B">B. Cassim</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Geriatrics, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal</s1><s2>Durban</s2><s3>ZAF</s3><sZ>6 aut.</sZ></inist:fA14><country>Afrique du Sud</country><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Cerreta, F" uniqKey="Cerreta F">F. Cerreta</name><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>European Medicines Agency (EMA)</s1><s2>London</s2><s3>GBR</s3><sZ>7 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Cesari, M" uniqKey="Cesari M">M. Cesari</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Gérontopole, Service de Santé Publique, CHU de Toulouse</s1><s3>FRA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>CHU de Toulouse</wicri:noRegion><wicri:noRegion>Gérontopole, Service de Santé Publique, CHU de Toulouse</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM 1027</s1><s2>Toulouse</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ><sZ>34 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Cha, H B" uniqKey="Cha H">H. B. Cha</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Social Welfare, Hallym University</s1><s2>Chuncheon, Gangwon-do</s2><s3>KOR</s3><sZ>9 aut.</sZ></inist:fA14><country>Corée du Sud</country><wicri:noRegion>Chuncheon, Gangwon-do</wicri:noRegion></affiliation></author><author><name sortKey="Chen, L K" uniqKey="Chen L">L. K. Chen</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Center for Geriatrics and Gerontology, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>10 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Cherubini, A" uniqKey="Cherubini A">A. Cherubini</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Geriatrics, IRCCS-INRCA</s1><s2>Ancona</s2><s3>ITA</s3><sZ>11 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Ancona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, Policlinico Santa Maria della Misericordia, University of Perugia Medical School</s1><s2>Perrugia</s2><s3>ITA</s3><sZ>11 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Perrugia</wicri:noRegion></affiliation></author><author><name sortKey="Chou, M Y" uniqKey="Chou M">M. Y. Chou</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Geriatric Medicine Center, Kaohsiung Veterans General Hospital</s1><s2>Kaohsiung City</s2><s3>TWN</s3><sZ>12 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>Kaohsiung City</wicri:noRegion></affiliation></author><author><name sortKey="Cruz Jentoft, A J" uniqKey="Cruz Jentoft A">A. J. Cruz-Jentoft</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Geriatric Department, Hospital Universitario Ramón y Cajal</s1><s2>Madrid</s2><s3>ESP</s3><sZ>13 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Madrid</wicri:noRegion></affiliation></author><author><name sortKey="De Decker, L" uniqKey="De Decker L">L. De Decker</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Pôle Hospitalo-Universitaire de Gérontologie Clinique, CHU Nantes</s1><s2>Nantes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Du, P" uniqKey="Du P">P. Du</name><affiliation wicri:level="3"><inist:fA14 i1="15"><s1>Academic Research Office, Remnin University</s1><s2>Beijing</s2><s3>CHN</s3><sZ>15 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Forette, B" uniqKey="Forette B">B. Forette</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Hôpital Sainte Perrine</s1><s2>Paris</s2><s3>FRA</s3><sZ>16 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Forette, F" uniqKey="Forette F">F. Forette</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>ILC-International Longevity Center</s1><s2>Paris</s2><s3>FRA</s3><sZ>17 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Franco, A" uniqKey="Franco A">A. Franco</name><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Département de Médecine Gériatrique, CHU de Nice</s1><s2>Nice</s2><s3>FRA</s3><sZ>18 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Provence-Alpes-Côte d'Azur</region><settlement type="city">Nice</settlement></placeName></affiliation></author><author><name sortKey="Guimaraes, R" uniqKey="Guimaraes R">R. Guimaraes</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>School of Health Sciences</s1><s2>Brasília</s2><s3>BRA</s3><sZ>19 aut.</sZ></inist:fA14><country>Brésil</country><wicri:noRegion>School of Health Sciences</wicri:noRegion></affiliation></author><author><name sortKey="Gutierrez Robledo, L M" uniqKey="Gutierrez Robledo L">L. M. Gutierrez-Robledo</name><affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Institute Nacional de Geriatría</s1><s2>Mexico City</s2><s3>MEX</s3><sZ>20 aut.</sZ></inist:fA14><country>Mexique</country><wicri:noRegion>Institute Nacional de Geriatría</wicri:noRegion></affiliation></author><author><name sortKey="Jauregui, J" uniqKey="Jauregui J">J. Jauregui</name><affiliation wicri:level="1"><inist:fA14 i1="21"><s1>Hospital Italiano</s1><s2>Buenos Aires</s2><s3>ARG</s3><sZ>21 aut.</sZ></inist:fA14><country>Argentine</country><wicri:noRegion>Hospital Italiano</wicri:noRegion></affiliation></author><author><name sortKey="Khavinson, V" uniqKey="Khavinson V">V. Khavinson</name><affiliation wicri:level="1"><inist:fA14 i1="22"><s1>St Petersburg Institute of Bioregulation and Gerontology</s1><s2>St Petersburg</s2><s3>RUS</s3><sZ>22 aut.</sZ></inist:fA14><country>Russie</country><wicri:noRegion>St Petersburg Institute of Bioregulation and Gerontology</wicri:noRegion></affiliation></author><author><name sortKey="Lee, W J" uniqKey="Lee W">W. J. Lee</name><affiliation wicri:level="1"><inist:fA14 i1="23"><s1>Division of Geriatric Medicine, Taipei Veterans General Hospital, Yuanshan Branch</s1><s2>I-Lan</s2><s3>TWN</s3><sZ>23 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>I-Lan</wicri:noRegion></affiliation></author><author><name sortKey="Peng, L N" uniqKey="Peng L">L. N. Peng</name><affiliation wicri:level="1"><inist:fA14 i1="24"><s1>Division of Geriatric Medicine, Center for Geriatrics and Gerontology, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>24 aut.</sZ></inist:fA14><country>Taïwan</country><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Perret Guillaume, C" uniqKey="Perret Guillaume C">C. Perret-Guillaume</name><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>Département de Médecine Gériatrique, CHU de Nancy, Vandoeuvre les Nancy</s1><s3>FRA</s3><sZ>25 aut.</sZ><sZ>35 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région" nuts="2">Lorraine</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Petrovic, M" uniqKey="Petrovic M">M. Petrovic</name></author><author><name sortKey="Retornaz, F" uniqKey="Retornaz F">F. Retornaz</name></author><author><name sortKey="Rockwood, K" uniqKey="Rockwood K">K. Rockwood</name></author><author><name sortKey="Rodriguez Manas, L" uniqKey="Rodriguez Manas L">L. Rodriguez-Manas</name></author><author><name sortKey="Sieber, C" uniqKey="Sieber C">C. Sieber</name></author><author><name sortKey="Spatharakis, G" uniqKey="Spatharakis G">G. Spatharakis</name></author><author><name sortKey="Theou, O" uniqKey="Theou O">O. Theou</name></author><author><name sortKey="Topinkova, E" uniqKey="Topinkova E">E. Topinkova</name></author><author><name sortKey="Vellas, B" uniqKey="Vellas B">B. Vellas</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>INSERM 1027</s1><s2>Toulouse</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ><sZ>34 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Benetos, A" uniqKey="Benetos A">A. Benetos</name><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>Département de Médecine Gériatrique, CHU de Nancy, Vandoeuvre les Nancy</s1><s3>FRA</s3><sZ>25 aut.</sZ><sZ>35 aut.</sZ></inist:fA14><country>France</country><placeName><region type="région" nuts="2">Lorraine</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="inist">13-0332737</idno><date when="2013">2013</date><idno type="stanalyst">PASCAL 13-0332737 INIST</idno><idno type="RBID">Pascal:13-0332737</idno><idno type="wicri:Area/Main/Corpus">000421</idno><idno type="wicri:Area/Main/Curation">002450</idno><idno type="wicri:Area/Main/Exploration">000399</idno></publicationStmt><seriesStmt><idno type="ISSN">1279-7707</idno><title level="j" type="abbreviated">J. nutr. health aging</title><title level="j" type="main">The Journal of nutrition, health & aging</title></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Accessibility</term><term>Association</term><term>Diagnosis</term><term>Geriatrics</term><term>Metabolic diseases</term><term>WHO</term><term>Workshop</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Accessibilité</term><term>Association</term><term>Gériatrie</term><term>OMS</term><term>Atelier</term><term>Diagnostic</term><term>Maladie métabolique</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Association</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Frailty tends to be considered as a major risk for adverse outcomes in older persons, but some important aspects remain matter of debate. Objectives: The purpose of this paper is to present expert's positions on the main aspects of the frailty syndrome in the older persons. Participants: Workshop organized by International Association of Gerontology and Geriatrics (IAGG), World Health Organization (WHO) and Société Française de Gériatrie et de Gérontologie (SFGG). Results: Frailty is widely recognized as an important risk factor for adverse health outcomes in older persons. This can be of particular value in evaluating non-disabled older persons with chronic diseases but today no operational definition has been established. Nutritional status, mobility, activity, strength, endurance, cognition, and mood have been proposed as markers of frailty. Another approach calculates a multidimensional score ranging from "very fit" to "severely frail," but it is difficult to apply into the medical practice. Frailty appears to be secondary to multiple conditions using multiple pathways leading to a vulnerability to a stressor. Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.), as well as social factors (isolation, financial situation) are involved in the vulnerability process. In clinical practice, detection of frailty is of major interest in oncology because of the high prevalence of cancer in older persons and the bad tolerance of the drug therapies. Presence of frailty should also be taken into account in the definition of the cardiovascular risks in the older population. The experts of the workshop have listed the points reached an agreement and those must to be a priority for improving understanding and use of frailty syndrome in practice. Conclusion: Frailty in older adults is a syndrome corresponding to a vulnerability to a stressor. Diagnostic tools have been developed but none can integrate at the same time the large spectrum of factors and the simplicity asked by the clinical practice. An agreement with an international common definition is necessary to develop screening and to reduce the morbidity in older persons.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>1279-7707</s0></fA01><fA03 i2="1"><s0>J. nutr. health aging</s0></fA03><fA05><s2>17</s2></fA05><fA06><s2>8</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>PROMOTING ACCESS TO INNOVATION FOR FRAIL OLD PERSONS: IAGG (INTERNATIONAL ASSOCIATION OF GERONTOLOGY AND GERIATRICS), WHO (WORLD HEALTH ORGANIZATION) AND SFGG (SOCIETE FRANCAISE DE GERIATRIE ET DE GERONTOLOGIE) WORKSHOP - ATHENS JANUARY 20-21, 2012</s1></fA08><fA11 i1="01" i2="1"><s1>BERRUT (G.)</s1></fA11><fA11 i1="02" i2="1"><s1>ANDRIEU (S.)</s1></fA11><fA11 i1="03" i2="1"><s1>DE CARVALHO (I. Araujo)</s1></fA11><fA11 i1="04" i2="1"><s1>BAEYENS (J. P.)</s1></fA11><fA11 i1="05" i2="1"><s1>BERGMAN (H.)</s1></fA11><fA11 i1="06" i2="1"><s1>CASSIM (B.)</s1></fA11><fA11 i1="07" i2="1"><s1>CERRETA (F.)</s1></fA11><fA11 i1="08" i2="1"><s1>CESARI (M.)</s1></fA11><fA11 i1="09" i2="1"><s1>CHA (H. B.)</s1></fA11><fA11 i1="10" i2="1"><s1>CHEN (L. K.)</s1></fA11><fA11 i1="11" i2="1"><s1>CHERUBINI (A.)</s1></fA11><fA11 i1="12" i2="1"><s1>CHOU (M. Y.)</s1></fA11><fA11 i1="13" i2="1"><s1>CRUZ-JENTOFT (A. J.)</s1></fA11><fA11 i1="14" i2="1"><s1>DE DECKER (L.)</s1></fA11><fA11 i1="15" i2="1"><s1>DU (P.)</s1></fA11><fA11 i1="16" i2="1"><s1>FORETTE (B.)</s1></fA11><fA11 i1="17" i2="1"><s1>FORETTE (F.)</s1></fA11><fA11 i1="18" i2="1"><s1>FRANCO (A.)</s1></fA11><fA11 i1="19" i2="1"><s1>GUIMARAES (R.)</s1></fA11><fA11 i1="20" i2="1"><s1>GUTIERREZ-ROBLEDO (L. M.)</s1></fA11><fA11 i1="21" i2="1"><s1>JAUREGUI (J.)</s1></fA11><fA11 i1="22" i2="1"><s1>KHAVINSON (V.)</s1></fA11><fA11 i1="23" i2="1"><s1>LEE (W. J.)</s1></fA11><fA11 i1="24" i2="1"><s1>PENG (L. N.)</s1></fA11><fA11 i1="25" i2="1"><s1>PERRET-GUILLAUME (C.)</s1></fA11><fA11 i1="26" i2="1"><s1>PETROVIC (M.)</s1></fA11><fA11 i1="27" i2="1"><s1>RETORNAZ (F.)</s1></fA11><fA11 i1="28" i2="1"><s1>ROCKWOOD (K.)</s1></fA11><fA11 i1="29" i2="1"><s1>RODRIGUEZ-MANAS (L.)</s1></fA11><fA11 i1="30" i2="1"><s1>SIEBER (C.)</s1></fA11><fA11 i1="31" i2="1"><s1>SPATHARAKIS (G.)</s1></fA11><fA11 i1="32" i2="1"><s1>THEOU (O.)</s1></fA11><fA11 i1="33" i2="1"><s1>TOPINKOVA (E.)</s1></fA11><fA11 i1="34" i2="1"><s1>VELLAS (B.)</s1></fA11><fA11 i1="35" i2="1"><s1>BENETOS (A.)</s1></fA11><fA14 i1="01"><s1>Pôle Hospitalo-Universitaire de Gérontologie Clinique, CHU Nantes</s1><s2>Nantes</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>14 aut.</sZ></fA14><fA14 i1="02"><s1>Gérontopole, Service de Santé Publique, CHU de Toulouse</s1><s3>FRA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ></fA14><fA14 i1="03"><s1>INSERM 1027</s1><s2>Toulouse</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ><sZ>34 aut.</sZ></fA14><fA14 i1="04"><s1>Department of Gender, Women and Health, World Health Organization (WHO)</s1><s2>Geneva</s2><s3>CHE</s3><sZ>3 aut.</sZ></fA14><fA14 i1="05"><s1>Department of Geriatric Medicine, Damiaan General Hospital</s1><s2>Ostend</s2><s3>BEL</s3><sZ>4 aut.</sZ></fA14><fA14 i1="06"><s1>Department of Family Medicine, Mc Gill University</s1><s2>Montreal</s2><s3>CAN</s3><sZ>5 aut.</sZ></fA14><fA14 i1="07"><s1>Department of Geriatrics, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal</s1><s2>Durban</s2><s3>ZAF</s3><sZ>6 aut.</sZ></fA14><fA14 i1="08"><s1>European Medicines Agency (EMA)</s1><s2>London</s2><s3>GBR</s3><sZ>7 aut.</sZ></fA14><fA14 i1="09"><s1>Department of Social Welfare, Hallym University</s1><s2>Chuncheon, Gangwon-do</s2><s3>KOR</s3><sZ>9 aut.</sZ></fA14><fA14 i1="10"><s1>Center for Geriatrics and Gerontology, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>10 aut.</sZ></fA14><fA14 i1="11"><s1>Geriatrics, IRCCS-INRCA</s1><s2>Ancona</s2><s3>ITA</s3><sZ>11 aut.</sZ></fA14><fA14 i1="12"><s1>Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, Policlinico Santa Maria della Misericordia, University of Perugia Medical School</s1><s2>Perrugia</s2><s3>ITA</s3><sZ>11 aut.</sZ></fA14><fA14 i1="13"><s1>Geriatric Medicine Center, Kaohsiung Veterans General Hospital</s1><s2>Kaohsiung City</s2><s3>TWN</s3><sZ>12 aut.</sZ></fA14><fA14 i1="14"><s1>Geriatric Department, Hospital Universitario Ramón y Cajal</s1><s2>Madrid</s2><s3>ESP</s3><sZ>13 aut.</sZ></fA14><fA14 i1="15"><s1>Academic Research Office, Remnin University</s1><s2>Beijing</s2><s3>CHN</s3><sZ>15 aut.</sZ></fA14><fA14 i1="16"><s1>Hôpital Sainte Perrine</s1><s2>Paris</s2><s3>FRA</s3><sZ>16 aut.</sZ></fA14><fA14 i1="17"><s1>ILC-International Longevity Center</s1><s2>Paris</s2><s3>FRA</s3><sZ>17 aut.</sZ></fA14><fA14 i1="18"><s1>Département de Médecine Gériatrique, CHU de Nice</s1><s2>Nice</s2><s3>FRA</s3><sZ>18 aut.</sZ></fA14><fA14 i1="19"><s1>School of Health Sciences</s1><s2>Brasília</s2><s3>BRA</s3><sZ>19 aut.</sZ></fA14><fA14 i1="20"><s1>Institute Nacional de Geriatría</s1><s2>Mexico City</s2><s3>MEX</s3><sZ>20 aut.</sZ></fA14><fA14 i1="21"><s1>Hospital Italiano</s1><s2>Buenos Aires</s2><s3>ARG</s3><sZ>21 aut.</sZ></fA14><fA14 i1="22"><s1>St Petersburg Institute of Bioregulation and Gerontology</s1><s2>St Petersburg</s2><s3>RUS</s3><sZ>22 aut.</sZ></fA14><fA14 i1="23"><s1>Division of Geriatric Medicine, Taipei Veterans General Hospital, Yuanshan Branch</s1><s2>I-Lan</s2><s3>TWN</s3><sZ>23 aut.</sZ></fA14><fA14 i1="24"><s1>Division of Geriatric Medicine, Center for Geriatrics and Gerontology, Taipei Veterans General Hospital</s1><s2>Taipei</s2><s3>TWN</s3><sZ>24 aut.</sZ></fA14><fA14 i1="25"><s1>Département de Médecine Gériatrique, CHU de Nancy, Vandoeuvre les Nancy</s1><s3>FRA</s3><sZ>25 aut.</sZ><sZ>35 aut.</sZ></fA14><fA20><s1>688-693</s1></fA20><fA21><s1>2013</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>26862</s2><s5>354000504205700080</s5></fA43><fA44><s0>0000</s0><s1>© 2013 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>51 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>13-0332737</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>The Journal of nutrition, health & aging</s0></fA64><fA66 i1="01"><s0>FRA</s0></fA66><fC01 i1="01" l="ENG"><s0>Frailty tends to be considered as a major risk for adverse outcomes in older persons, but some important aspects remain matter of debate. Objectives: The purpose of this paper is to present expert's positions on the main aspects of the frailty syndrome in the older persons. Participants: Workshop organized by International Association of Gerontology and Geriatrics (IAGG), World Health Organization (WHO) and Société Française de Gériatrie et de Gérontologie (SFGG). Results: Frailty is widely recognized as an important risk factor for adverse health outcomes in older persons. This can be of particular value in evaluating non-disabled older persons with chronic diseases but today no operational definition has been established. Nutritional status, mobility, activity, strength, endurance, cognition, and mood have been proposed as markers of frailty. Another approach calculates a multidimensional score ranging from "very fit" to "severely frail," but it is difficult to apply into the medical practice. Frailty appears to be secondary to multiple conditions using multiple pathways leading to a vulnerability to a stressor. Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc.), as well as social factors (isolation, financial situation) are involved in the vulnerability process. In clinical practice, detection of frailty is of major interest in oncology because of the high prevalence of cancer in older persons and the bad tolerance of the drug therapies. Presence of frailty should also be taken into account in the definition of the cardiovascular risks in the older population. The experts of the workshop have listed the points reached an agreement and those must to be a priority for improving understanding and use of frailty syndrome in practice. Conclusion: Frailty in older adults is a syndrome corresponding to a vulnerability to a stressor. Diagnostic tools have been developed but none can integrate at the same time the large spectrum of factors and the simplicity asked by the clinical practice. An agreement with an international common definition is necessary to develop screening and to reduce the morbidity in older persons.</s0></fC01><fC02 i1="01" i2="X"><s0>002A16E</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Accessibilité</s0><s5>02</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Accessibility</s0><s5>02</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Accesibilidad</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Association</s0><s5>03</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Association</s0><s5>03</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Asociación</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Gériatrie</s0><s5>05</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Geriatrics</s0><s5>05</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Geriatría</s0><s5>05</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>OMS</s0><s5>06</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>WHO</s0><s5>06</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>OMS</s0><s5>06</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Atelier</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Workshop</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Taller</s0><s5>08</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Diagnostic</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Diagnosis</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Diagnóstico</s0><s5>09</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Maladie métabolique</s0><s5>11</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Metabolic diseases</s0><s5>11</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Metabolismo patología</s0><s5>11</s5></fC03><fN21><s1>315</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist></record>Pour manipuler ce document sous Unix (Dilib)
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|wiki= *** parameter Area/wikiCode missing ***
|area= FranceBresilV1
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|clé= Pascal:13-0332737
|texte= PROMOTING ACCESS TO INNOVATION FOR FRAIL OLD PERSONS: IAGG (INTERNATIONAL ASSOCIATION OF GERONTOLOGY AND GERIATRICS), WHO (WORLD HEALTH ORGANIZATION) AND SFGG (SOCIETE FRANCAISE DE GERIATRIE ET DE GERONTOLOGIE) WORKSHOP - ATHENS JANUARY 20-21, 2012
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