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NAD + -dependent Formate Dehydrogenase from Plants

Identifieur interne : 000F99 ( Ncbi/Checkpoint ); précédent : 000F98; suivant : 001000

NAD + -dependent Formate Dehydrogenase from Plants

Auteurs : A. A. Alekseeva ; S. S. Savin ; V. I. Tishkov

Source :

RBID : PMC:3347622

Abstract

NAD+-dependent formate dehydrogenase (FDH, EC 1.2.1.2) widely occurs in nature. FDH consists of two identical subunits and contains neither prosthetic groups nor metal ions. This type of FDH was found in different microorganisms (including pathogenic ones), such as bacteria, yeasts, fungi, and plants. As opposed to microbiological FDHs functioning in cytoplasm, plant FDHs localize in mitochondria. Formate dehydrogenase activity was first discovered as early as in 1921 in plant; however, until the past decade FDHs from plants had been considerably less studied than the enzymes from microorganisms. This review summarizes the recent results on studying the physiological role, properties, structure, and protein engineering of plant formate dehydrogenases.


Url:
PubMed: 22649703
PubMed Central: 3347622


Affiliations:


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PMC:3347622

Le document en format XML

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<sup>+</sup>
-dependent Formate Dehydrogenase from Plants </title>
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<sup>+</sup>
-dependent Formate Dehydrogenase from Plants </title>
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<p>NAD
<sup>+</sup>
-dependent formate dehydrogenase (FDH, EC 1.2.1.2) widely occurs in nature. FDH consists of two identical subunits and contains neither prosthetic groups nor metal ions. This type of FDH was found in different microorganisms (including pathogenic ones), such as bacteria, yeasts, fungi, and plants. As opposed to microbiological FDHs functioning in cytoplasm, plant FDHs localize in mitochondria. Formate dehydrogenase activity was first discovered as early as in 1921 in plant; however, until the past decade FDHs from plants had been considerably less studied than the enzymes from microorganisms. This review summarizes the recent results on studying the physiological role, properties, structure, and protein engineering of plant formate dehydrogenases.</p>
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