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Chemopreventive Actions of Blond and Red-Fleshed Sweet Orange Juice on the Loucy Leukemia Cell Line.

Identifieur interne : 000748 ( Main/Merge ); précédent : 000747; suivant : 000749

Chemopreventive Actions of Blond and Red-Fleshed Sweet Orange Juice on the Loucy Leukemia Cell Line.

Auteurs : Grace K Z S. Dourado [Brésil] ; Joy M. Stanilka ; Susan S. Percival ; Thais B. Cesar

Source :

RBID : pubmed:26434864

English descriptors

Abstract

Red-fleshed sweet orange juice (ROJ) comes from a new variety of citrus cultivated in Brazil that contains high levels of β-carotene and lycopene, and similar amounts of hesperidin (HSP) and nutrients, equivalently to blond orange juice (BOJ). Such bioactive compounds are associated with chemopreventive actions in several cancer cell lines. The purpose of this study was to examine the cytotoxicity, cell cycle, apoptosis, and cytokine secretion after BOJ, ROJ, and HSP treatment of a novel T acute lymphoblastic leukemia cell line, Loucy.

PubMed: 26434864

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pubmed:26434864

Le document en format XML

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<nlm:affiliation>Food and Nutrition, Pharmaceutical School, Universidade Estadual Paulista, Araraquara, Brazil E-mail : tcesar@fcfar.unesp.br.</nlm:affiliation>
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<term>Carotenoids (analysis)</term>
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<term>Fruit and Vegetable Juices</term>
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<term>Interleukin-10 (secretion)</term>
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<term>Plant Preparations (chemistry)</term>
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<div type="abstract" xml:lang="en">Red-fleshed sweet orange juice (ROJ) comes from a new variety of citrus cultivated in Brazil that contains high levels of β-carotene and lycopene, and similar amounts of hesperidin (HSP) and nutrients, equivalently to blond orange juice (BOJ). Such bioactive compounds are associated with chemopreventive actions in several cancer cell lines. The purpose of this study was to examine the cytotoxicity, cell cycle, apoptosis, and cytokine secretion after BOJ, ROJ, and HSP treatment of a novel T acute lymphoblastic leukemia cell line, Loucy.</div>
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