Food Insecurity and CD4% among HIV+ Children in Gaborone, Botswana
Identifieur interne : 001927 ( Pmc/Curation ); précédent : 001926; suivant : 001928Food Insecurity and CD4% among HIV+ Children in Gaborone, Botswana
Auteurs : Jason A. Mendoza [États-Unis] ; Mogomotsi Matshaba [Botswana, États-Unis] ; Jeremiah Makhanda [Botswana] ; Yan Liu [États-Unis] ; Matshwenyego Boitshwarelo [Botswana] ; Gabriel M. Anabwani [Botswana, États-Unis]Source :
- Journal of acquired immune deficiency syndromes (1999) [ 1525-4135 ] ; 2014.
Abstract
We investigated the association between household food insecurity (HFI) and CD4% among 2-6 year old HIV+ outpatients (n=78) at the Botswana-Baylor Children's Clinical Center of Excellence in Gaborone, Botswana. HFI was assessed by a validated survey. CD4% data were abstracted from the medical record. We used multiple linear regression with CD4% (dependent variable), HFI (independent variable), and controlled for socio-demographic and clinical covariates. Multiple linear regression showed a significant main effect for HFI (beta=−0.6, 95% CI [−1.0, −0.1]) and child gender (beta=5.6, 95% CI [1.3, 9.8]). Alleviating food insecurity may improve pediatric HIV outcomes in Botswana and similar Sub-Saharan settings.
Url:
DOI: 10.1097/QAI.0000000000000190
PubMed: 24798763
PubMed Central: 4205044
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<front><div type="abstract" xml:lang="en"><p id="P1">We investigated the association between household food insecurity (HFI) and CD4% among 2-6 year old HIV+ outpatients (n=78) at the Botswana-Baylor Children's Clinical Center of Excellence in Gaborone, Botswana. HFI was assessed by a validated survey. CD4% data were abstracted from the medical record. We used multiple linear regression with CD4% (dependent variable), HFI (independent variable), and controlled for socio-demographic and clinical covariates. Multiple linear regression showed a significant main effect for HFI (beta=−0.6, 95% CI [−1.0, −0.1]) and child gender (beta=5.6, 95% CI [1.3, 9.8]). Alleviating food insecurity may improve pediatric HIV outcomes in Botswana and similar Sub-Saharan settings.</p>
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<given-names>Jason A</given-names>
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General Pediatrics, Department of Pediatrics, University of Washington, Seattle WA, USA</aff>
<aff id="A2"><label>2</label>
Center for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, USA</aff>
<aff id="A3"><label>3</label>
Botswana-Baylor Children's Clinical Center of Excellence, Gaborone, Botswana</aff>
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Retrovirology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA</aff>
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Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA</aff>
<author-notes><corresp id="CR1"><label>*</label>
Correspondence: Jason A Mendoza, Seattle Children's Research Institute, PO Box 5371, Suite 400, M/S: CW8-6, Seattle, WA 98145-5005; <email>jason.mendoza@seattlechildrens.org</email>
; 206.884.1261 (telephone); 206.884.7803 (fax)</corresp>
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<pub-date pub-type="nihms-submitted"><day>29</day>
<month>5</month>
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<pub-date pub-type="pmc-release"><day>01</day>
<month>8</month>
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<volume>66</volume>
<issue>4</issue>
<fpage>414</fpage>
<lpage>418</lpage>
<pmc-comment>elocation-id from pubmed: 10.1097/QAI.0000000000000190</pmc-comment>
<abstract><p id="P1">We investigated the association between household food insecurity (HFI) and CD4% among 2-6 year old HIV+ outpatients (n=78) at the Botswana-Baylor Children's Clinical Center of Excellence in Gaborone, Botswana. HFI was assessed by a validated survey. CD4% data were abstracted from the medical record. We used multiple linear regression with CD4% (dependent variable), HFI (independent variable), and controlled for socio-demographic and clinical covariates. Multiple linear regression showed a significant main effect for HFI (beta=−0.6, 95% CI [−1.0, −0.1]) and child gender (beta=5.6, 95% CI [1.3, 9.8]). Alleviating food insecurity may improve pediatric HIV outcomes in Botswana and similar Sub-Saharan settings.</p>
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