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<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Screening and treatment of immigrants and refugees to Canada for tuberculosis: Implications of the experience of Canada and other industrialized countries</title>
<author>
<name sortKey="Thomas, Roger E" sort="Thomas, Roger E" uniqKey="Thomas R" first="Roger E" last="Thomas">Roger E. Thomas</name>
</author>
<author>
<name sortKey="Gushulak, Brian" sort="Gushulak, Brian" uniqKey="Gushulak B" first="Brian" last="Gushulak">Brian Gushulak</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">22514407</idno>
<idno type="pmc">3327927</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327927</idno>
<idno type="RBID">PMC:3327927</idno>
<date when="1995">1995</date>
<idno type="wicri:Area/Pmc/Corpus">002D61</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D61</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en" level="a" type="main">Screening and treatment of immigrants and refugees to Canada for tuberculosis: Implications of the experience of Canada and other industrialized countries</title>
<author>
<name sortKey="Thomas, Roger E" sort="Thomas, Roger E" uniqKey="Thomas R" first="Roger E" last="Thomas">Roger E. Thomas</name>
</author>
<author>
<name sortKey="Gushulak, Brian" sort="Gushulak, Brian" uniqKey="Gushulak B" first="Brian" last="Gushulak">Brian Gushulak</name>
</author>
</analytic>
<series>
<title level="j">The Canadian Journal of Infectious Diseases</title>
<idno type="ISSN">1180-2332</idno>
<imprint>
<date when="1995">1995</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec>
<title>Objective:</title>
<p>To assess the incidence of tuberculosis in immigrants and refugees in Canada and other industrialized countries; the effectiveness of the screening process; the incidence of drug resistance; recommendations for prophylaxis and therapy; and indications for and effectiveness of directly observed therapy.</p>
</sec>
<sec>
<title>Data Sources:</title>
<p>
<sc>medline</sc>
search of literature published from 1985 to 1995 with the key words ‘tuberculosis’, ‘Canada’, ‘screening’, ‘drug resistance’, ‘drug resistance, multiple’, ‘immigration and emigration’, and the title words ‘directly observed therapy’.</p>
</sec>
<sec>
<title>Study Selection:</title>
<p>All studies reporting data on incidence, the outcomes of screening, drug resistance, therapy and directly observed therapy were selected.</p>
</sec>
<sec>
<title>Data Synthesis and Conclusions:</title>
<p>Data synthesis led to the conclusions that immigrants and refugees to Canada have five times the nonimmigrant and non-Aboriginal rate of tuberculosis; that screening programs discover new cases of tuberculosis on and after arrival and that up to 20% of those scheduled to attend a tuberculosis clinic after arrival may never attend; that drug resistance is widespread in countries from which Canada receives immigrants; and that directly observed therapy for active cases can result in 100% conversion rates.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="review-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Can J Infect Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Can J Infect Dis</journal-id>
<journal-id journal-id-type="publisher-id">PGI</journal-id>
<journal-title-group>
<journal-title>The Canadian Journal of Infectious Diseases</journal-title>
</journal-title-group>
<issn pub-type="ppub">1180-2332</issn>
<publisher>
<publisher-name>Pulsus Group Inc</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">22514407</article-id>
<article-id pub-id-type="pmc">3327927</article-id>
<article-id pub-id-type="publisher-id">idmm06246</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Review</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Screening and treatment of immigrants and refugees to Canada for tuberculosis: Implications of the experience of Canada and other industrialized countries</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Thomas</surname>
<given-names>Roger E</given-names>
</name>
<degrees>MD PhD CCFP MRCGP</degrees>
<xref ref-type="corresp" rid="c1-idmm06246"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gushulak</surname>
<given-names>Brian</given-names>
</name>
<degrees>BSc MD</degrees>
</contrib>
<aff id="af1-idmm06246">Elisabeth Bruyère Health Centre, University of Ottawa, and Quarantine Health Services, Laboratory Centre for Disease Control, Health Canada, Ottawa, Ontario</aff>
</contrib-group>
<author-notes>
<corresp id="c1-idmm06246">Correspondence: Dr RE Thomas, Elisabeth Bruyère Health Centre, 75 Bruyère Street, Ottawa, Ontario K1N 5C8. Telephone 613-241-3344, fax 613-241-1971</corresp>
</author-notes>
<pub-date pub-type="ppub">
<season>Sep-Oct</season>
<year>1995</year>
</pub-date>
<volume>6</volume>
<issue>5</issue>
<fpage>246</fpage>
<lpage>255</lpage>
<history>
<date date-type="received">
<day>9</day>
<month>1</month>
<year>1995</year>
</date>
<date date-type="accepted">
<day>13</day>
<month>6</month>
<year>1995</year>
</date>
</history>
<permissions>
<copyright-statement>©1995 Pulsus Group Inc. All rights reserved</copyright-statement>
<copyright-year>1995</copyright-year>
</permissions>
<abstract>
<sec>
<title>Objective:</title>
<p>To assess the incidence of tuberculosis in immigrants and refugees in Canada and other industrialized countries; the effectiveness of the screening process; the incidence of drug resistance; recommendations for prophylaxis and therapy; and indications for and effectiveness of directly observed therapy.</p>
</sec>
<sec>
<title>Data Sources:</title>
<p>
<sc>medline</sc>
search of literature published from 1985 to 1995 with the key words ‘tuberculosis’, ‘Canada’, ‘screening’, ‘drug resistance’, ‘drug resistance, multiple’, ‘immigration and emigration’, and the title words ‘directly observed therapy’.</p>
</sec>
<sec>
<title>Study Selection:</title>
<p>All studies reporting data on incidence, the outcomes of screening, drug resistance, therapy and directly observed therapy were selected.</p>
</sec>
<sec>
<title>Data Synthesis and Conclusions:</title>
<p>Data synthesis led to the conclusions that immigrants and refugees to Canada have five times the nonimmigrant and non-Aboriginal rate of tuberculosis; that screening programs discover new cases of tuberculosis on and after arrival and that up to 20% of those scheduled to attend a tuberculosis clinic after arrival may never attend; that drug resistance is widespread in countries from which Canada receives immigrants; and that directly observed therapy for active cases can result in 100% conversion rates.</p>
</sec>
</abstract>
<trans-abstract xml:lang="fr">
<sec>
<title>Objectif :</title>
<p>Évaluer les répercussions de la tuberculose chez les immigrants et les réfugiés qui arrivent au Canada et dans d’autres pays industrialisés. L’efficacité du processus de dépistage, l’incidence de la résistance aux médicaments, les recommandations quant à la prophylaxie et au traitement et les indications, ainsi que l’efficacité d’un traitement observé directement sont présentés ici.</p>
</sec>
<sec>
<title>Sources des Données :</title>
<p>Interrogation du réseau
<sc>medline</sc>
sur les articles publiés de 1985 à 1995, avec pour mots clés «tuberculose», «Canada», «dépistage», «résistance médicamenteuse», «résistance médicamenteuse multiple», «immigration et émigration», et les mots titres «traitement directement observé».</p>
</sec>
<sec>
<title>Sélection des Études :</title>
<p>Toutes les études faisant état de données sur l’incidence, les résultats de dépistage, la résistance médicamenteuse, le traitement et le traitement directement observé ont été retenues.</p>
</sec>
<sec>
<title>Synthèse des Données et Conclusion :</title>
<p>La synthèse des données mène à la conclusion que les immigrants et les réfugiés qui arrivent au Canada souffrent cinq fois plus de tuberculose que les non-immigrants et les non-aborigènes; que les programmes de dépistage découvrent de nouveaux cas de tuberculose à l’arrivée et après, que jusqu’à 20 % des sujets attendus dans les cliniques de tuberculose après leur arrivée ne s’y présentent pas, que la résistance médicamenteuse est répandue dans les pays d’où arrivent les immigrants pour le Canada et que le traitement directement observé de cas actifs peut générer des taux de conversion de l’ordre de 100 %.</p>
</sec>
</trans-abstract>
<kwd-group>
<kwd>Directly observed therapy</kwd>
<kwd>Drug resistance</kwd>
<kwd>Immigration</kwd>
<kwd>Screening</kwd>
<kwd>Tuberculosis</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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