Le SIDA en Afrique subsaharienne (serveur d'exploration)

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<title xml:lang="en">Discordance of HIV and HSV-2 Biomarkers and Self-reported Sexual Behavior among Orphan Adolescents in Western Kenya</title>
<author>
<name sortKey="Cho, Hyunsan" sort="Cho, Hyunsan" uniqKey="Cho H" first="Hyunsan" last="Cho">Hyunsan Cho</name>
</author>
<author>
<name sortKey="Luseno, Winnie" sort="Luseno, Winnie" uniqKey="Luseno W" first="Winnie" last="Luseno">Winnie Luseno</name>
</author>
<author>
<name sortKey="Halpern, Carolyn" sort="Halpern, Carolyn" uniqKey="Halpern C" first="Carolyn" last="Halpern">Carolyn Halpern</name>
</author>
<author>
<name sortKey="Zhang, Lei" sort="Zhang, Lei" uniqKey="Zhang L" first="Lei" last="Zhang">Lei Zhang</name>
</author>
<author>
<name sortKey="Mbai, Isabella" sort="Mbai, Isabella" uniqKey="Mbai I" first="Isabella" last="Mbai">Isabella Mbai</name>
</author>
<author>
<name sortKey="Milimo, Benson" sort="Milimo, Benson" uniqKey="Milimo B" first="Benson" last="Milimo">Benson Milimo</name>
</author>
<author>
<name sortKey="Hallfors, Denise" sort="Hallfors, Denise" uniqKey="Hallfors D" first="Denise" last="Hallfors">Denise Hallfors</name>
</author>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">25378660</idno>
<idno type="pmc">4422775</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422775</idno>
<idno type="RBID">PMC:4422775</idno>
<idno type="doi">10.1136/sextrans-2014-051720</idno>
<date when="2014">2014</date>
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<title xml:lang="en" level="a" type="main">Discordance of HIV and HSV-2 Biomarkers and Self-reported Sexual Behavior among Orphan Adolescents in Western Kenya</title>
<author>
<name sortKey="Cho, Hyunsan" sort="Cho, Hyunsan" uniqKey="Cho H" first="Hyunsan" last="Cho">Hyunsan Cho</name>
</author>
<author>
<name sortKey="Luseno, Winnie" sort="Luseno, Winnie" uniqKey="Luseno W" first="Winnie" last="Luseno">Winnie Luseno</name>
</author>
<author>
<name sortKey="Halpern, Carolyn" sort="Halpern, Carolyn" uniqKey="Halpern C" first="Carolyn" last="Halpern">Carolyn Halpern</name>
</author>
<author>
<name sortKey="Zhang, Lei" sort="Zhang, Lei" uniqKey="Zhang L" first="Lei" last="Zhang">Lei Zhang</name>
</author>
<author>
<name sortKey="Mbai, Isabella" sort="Mbai, Isabella" uniqKey="Mbai I" first="Isabella" last="Mbai">Isabella Mbai</name>
</author>
<author>
<name sortKey="Milimo, Benson" sort="Milimo, Benson" uniqKey="Milimo B" first="Benson" last="Milimo">Benson Milimo</name>
</author>
<author>
<name sortKey="Hallfors, Denise" sort="Hallfors, Denise" uniqKey="Hallfors D" first="Denise" last="Hallfors">Denise Hallfors</name>
</author>
</analytic>
<series>
<title level="j">Sexually transmitted infections</title>
<idno type="ISSN">1368-4973</idno>
<idno type="eISSN">1472-3263</idno>
<imprint>
<date when="2014">2014</date>
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<front>
<div type="abstract" xml:lang="en">
<sec id="S1">
<title>Background</title>
<p id="P1">This paper examines the discordance between biological data of HIV and HSV-2 infections and self-reported questionnaire responses among orphan adolescents in Western Kenya.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">In 2011 a total of 837 orphan adolescents from 26 primary schools were enrolled in an HIV prevention trial. At baseline, blood samples were drawn for HIV and HSV-2 infection biomarker testing, and participants completed an audio computer-assisted self-interviewing (ACASI) survey.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Comparing biological data with self-reported responses indicated that 70% of HIV positive (7 out of 10) and 64% of HSV-2 positive (18 out of 28 positive) participants reported never having had sex. Among ever-married adolescents 65% (57 out of 88) reported never having had sex. Overall, 10% of study participants appeared to have inconsistently reported their sexual behavior. Logistic regression analyses indicated that lower educational level and exam scores were significant predictors of inconsistent reporting.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Our study demonstrates the discordance between infections measured by biomarkers and self-reports of having had sex among orphan adolescents in Kenya. In order to detect program effects accurately in prevention research, it is necessary to collect both baseline and endline biological data. Furthermore, it is recommended to triangulate multiple data sources about adolescent participants’ self-reported information about marriage and pregnancies from school records and parent/guardians to verify the information. Researchers should recognize potential threats to validity in data and design surveys to consider cognitive factors and/or cultural context to obtain more accurate and reliable information from adolescents regarding HIV/STI risk behaviors.</p>
</sec>
</div>
</front>
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<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">9805554</journal-id>
<journal-id journal-id-type="pubmed-jr-id">21009</journal-id>
<journal-id journal-id-type="nlm-ta">Sex Transm Infect</journal-id>
<journal-id journal-id-type="iso-abbrev">Sex Transm Infect</journal-id>
<journal-title-group>
<journal-title>Sexually transmitted infections</journal-title>
</journal-title-group>
<issn pub-type="ppub">1368-4973</issn>
<issn pub-type="epub">1472-3263</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">25378660</article-id>
<article-id pub-id-type="pmc">4422775</article-id>
<article-id pub-id-type="doi">10.1136/sextrans-2014-051720</article-id>
<article-id pub-id-type="manuscript">NIHMS661328</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Discordance of HIV and HSV-2 Biomarkers and Self-reported Sexual Behavior among Orphan Adolescents in Western Kenya</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Cho</surname>
<given-names>Hyunsan</given-names>
</name>
<aff id="A1">The Pacific Institute for Research and Evaluation, Chapel Hill, NC</aff>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Luseno</surname>
<given-names>Winnie</given-names>
</name>
<aff id="A2">The Pacific Institute for Research & Evaluation, Chapel Hill, NC</aff>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Halpern</surname>
<given-names>Carolyn</given-names>
</name>
<aff id="A3">The University of North Carolina at Chapel Hill, Dept. of Maternal and Child Health, Chapel Hill, NC</aff>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Zhang</surname>
<given-names>Lei</given-names>
</name>
<aff id="A4">The Pacific Institute for Research and Evaluation, Chapel Hill, NC</aff>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mbai</surname>
<given-names>Isabella</given-names>
</name>
<aff id="A5">Moi University, School of Nursing, Eldoret, Kenya</aff>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Milimo</surname>
<given-names>Benson</given-names>
</name>
<aff id="A6">Moi University, School of Nursing, Eldoret, Kenya</aff>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hallfors</surname>
<given-names>Denise</given-names>
</name>
<aff id="A7">The Pacific Institute for Research and Evaluation, Chapel Hill, NC</aff>
</contrib>
</contrib-group>
<author-notes>
<corresp id="FN1">Corresponding author: Hyunsan Cho, The Pacific Institute for Research and Evaluation, 1516 E. Franklin St., Suite 200, Chapel Hill, NC 27514, Phone – 919-265-2620 Fax – 919-265-2659,
<email>cho@pire.org</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>5</day>
<month>2</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub">
<day>06</day>
<month>11</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub">
<month>6</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>01</day>
<month>6</month>
<year>2016</year>
</pub-date>
<volume>91</volume>
<issue>4</issue>
<fpage>260</fpage>
<lpage>265</lpage>
<pmc-comment>elocation-id from pubmed: 10.1136/sextrans-2014-051720</pmc-comment>
<abstract>
<sec id="S1">
<title>Background</title>
<p id="P1">This paper examines the discordance between biological data of HIV and HSV-2 infections and self-reported questionnaire responses among orphan adolescents in Western Kenya.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">In 2011 a total of 837 orphan adolescents from 26 primary schools were enrolled in an HIV prevention trial. At baseline, blood samples were drawn for HIV and HSV-2 infection biomarker testing, and participants completed an audio computer-assisted self-interviewing (ACASI) survey.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Comparing biological data with self-reported responses indicated that 70% of HIV positive (7 out of 10) and 64% of HSV-2 positive (18 out of 28 positive) participants reported never having had sex. Among ever-married adolescents 65% (57 out of 88) reported never having had sex. Overall, 10% of study participants appeared to have inconsistently reported their sexual behavior. Logistic regression analyses indicated that lower educational level and exam scores were significant predictors of inconsistent reporting.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Our study demonstrates the discordance between infections measured by biomarkers and self-reports of having had sex among orphan adolescents in Kenya. In order to detect program effects accurately in prevention research, it is necessary to collect both baseline and endline biological data. Furthermore, it is recommended to triangulate multiple data sources about adolescent participants’ self-reported information about marriage and pregnancies from school records and parent/guardians to verify the information. Researchers should recognize potential threats to validity in data and design surveys to consider cognitive factors and/or cultural context to obtain more accurate and reliable information from adolescents regarding HIV/STI risk behaviors.</p>
</sec>
</abstract>
<kwd-group>
<kwd>HIV</kwd>
<kwd>HSV</kwd>
<kwd>Sexual behaviour</kwd>
<kwd>Adolescent</kwd>
<kwd>Africa</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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