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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Gender-specific risk factors for virologic failure in KwaZulu-Natal: Automobile ownership and financial insecurity</title><author><name sortKey="Hare, Anna Q" sort="Hare, Anna Q" uniqKey="Hare A" first="Anna Q." last="Hare">Anna Q. Hare</name><affiliation><nlm:aff id="A1">Emory University School of Medicine, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Ord Ez, Claudia E" sort="Ord Ez, Claudia E" uniqKey="Ord Ez C" first="Claudia E." last="Ord Ez">Claudia E. Ord Ez</name><affiliation><nlm:aff id="A2">McCord Hospital, Durban, South Africa</nlm:aff></affiliation></author><author><name sortKey="Johnson, Brent A" sort="Johnson, Brent A" uniqKey="Johnson B" first="Brent A." last="Johnson">Brent A. Johnson</name><affiliation><nlm:aff id="A3">Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Rio, Carlos Del" sort="Rio, Carlos Del" uniqKey="Rio C" first="Carlos Del" last="Rio">Carlos Del Rio</name><affiliation><nlm:aff id="A1">Emory University School of Medicine, Atlanta, Georgia, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A4">Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Kearns, Rachel A" sort="Kearns, Rachel A" uniqKey="Kearns R" first="Rachel A." last="Kearns">Rachel A. Kearns</name><affiliation><nlm:aff id="A5">Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Wu, Baohua" sort="Wu, Baohua" uniqKey="Wu B" first="Baohua" last="Wu">Baohua Wu</name><affiliation><nlm:aff id="A3">Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Hampton, Jane" sort="Hampton, Jane" uniqKey="Hampton J" first="Jane" last="Hampton">Jane Hampton</name><affiliation><nlm:aff id="A2">McCord Hospital, Durban, South Africa</nlm:aff></affiliation></author><author><name sortKey="Wu, Peng" sort="Wu, Peng" uniqKey="Wu P" first="Peng" last="Wu">Peng Wu</name><affiliation><nlm:aff id="A3">Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Sunpath, Henry" sort="Sunpath, Henry" uniqKey="Sunpath H" first="Henry" last="Sunpath">Henry Sunpath</name><affiliation><nlm:aff id="A2">McCord Hospital, Durban, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Infectious Diseases Unit, Nelson Mandela School of Medicine, University of KwaZulu-Natal, KwaZulu-Natal, South Africa</nlm:aff></affiliation></author><author><name sortKey="Marconi, Vincent C" sort="Marconi, Vincent C" uniqKey="Marconi V" first="Vincent C." last="Marconi">Vincent C. Marconi</name><affiliation><nlm:aff id="A1">Emory University School of Medicine, Atlanta, Georgia, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A4">Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25037488</idno><idno type="pmc">4198463</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198463</idno><idno type="RBID">PMC:4198463</idno><idno type="doi">10.1007/s10461-014-0849-1</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001F98</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001F98</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Gender-specific risk factors for virologic failure in KwaZulu-Natal: Automobile ownership and financial insecurity</title><author><name sortKey="Hare, Anna Q" sort="Hare, Anna Q" uniqKey="Hare A" first="Anna Q." last="Hare">Anna Q. Hare</name><affiliation><nlm:aff id="A1">Emory University School of Medicine, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Ord Ez, Claudia E" sort="Ord Ez, Claudia E" uniqKey="Ord Ez C" first="Claudia E." last="Ord Ez">Claudia E. Ord Ez</name><affiliation><nlm:aff id="A2">McCord Hospital, Durban, South Africa</nlm:aff></affiliation></author><author><name sortKey="Johnson, Brent A" sort="Johnson, Brent A" uniqKey="Johnson B" first="Brent A." last="Johnson">Brent A. Johnson</name><affiliation><nlm:aff id="A3">Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Rio, Carlos Del" sort="Rio, Carlos Del" uniqKey="Rio C" first="Carlos Del" last="Rio">Carlos Del Rio</name><affiliation><nlm:aff id="A1">Emory University School of Medicine, Atlanta, Georgia, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A4">Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Kearns, Rachel A" sort="Kearns, Rachel A" uniqKey="Kearns R" first="Rachel A." last="Kearns">Rachel A. Kearns</name><affiliation><nlm:aff id="A5">Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Wu, Baohua" sort="Wu, Baohua" uniqKey="Wu B" first="Baohua" last="Wu">Baohua Wu</name><affiliation><nlm:aff id="A3">Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Hampton, Jane" sort="Hampton, Jane" uniqKey="Hampton J" first="Jane" last="Hampton">Jane Hampton</name><affiliation><nlm:aff id="A2">McCord Hospital, Durban, South Africa</nlm:aff></affiliation></author><author><name sortKey="Wu, Peng" sort="Wu, Peng" uniqKey="Wu P" first="Peng" last="Wu">Peng Wu</name><affiliation><nlm:aff id="A3">Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Sunpath, Henry" sort="Sunpath, Henry" uniqKey="Sunpath H" first="Henry" last="Sunpath">Henry Sunpath</name><affiliation><nlm:aff id="A2">McCord Hospital, Durban, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Infectious Diseases Unit, Nelson Mandela School of Medicine, University of KwaZulu-Natal, KwaZulu-Natal, South Africa</nlm:aff></affiliation></author><author><name sortKey="Marconi, Vincent C" sort="Marconi, Vincent C" uniqKey="Marconi V" first="Vincent C." last="Marconi">Vincent C. Marconi</name><affiliation><nlm:aff id="A1">Emory University School of Medicine, Atlanta, Georgia, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A4">Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA</nlm:aff></affiliation></author></analytic><series><title level="j">AIDS and behavior</title><idno type="ISSN">1090-7165</idno><idno type="eISSN">1573-3254</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">We sought to examine which socioeconomic indicators are risk factors for virologic failure among HIV-1 infected patients receiving antiretroviral therapy in KwaZulu-Natal, South Africa. A case-control study of virologic failure was conducted among patients recruited from the outpatient clinic at McCord Hospital in Durban, South Africa between October 1, 2010 and June 30, 2012. Cases were those failing first-line antiretroviral therapy (ART), defined as viral load > 1000 copies/mL. Univariate logistic regression was performed on sociodemographic data for the outcome of virologic failure. Variables found significant (p<.05) were used in multivariate models and all models were stratified by gender. Of 158 cases and 300 controls, 35% were male and median age was 40 years. Gender stratification of models revealed automobile ownership was a risk factor among males, while variables of financial insecurity (unemployment, non-spouse family paying for care, staying with family) were risk factors for women. In this cohort, financial insecurity among women and automobile ownership among men were risk factors for virologic failure. Risk factor differences between genders demonstrate limitations of generalized risk factor analysis.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9712133</journal-id><journal-id journal-id-type="pubmed-jr-id">21042</journal-id><journal-id journal-id-type="nlm-ta">AIDS Behav</journal-id><journal-id journal-id-type="iso-abbrev">AIDS Behav</journal-id><journal-title-group><journal-title>AIDS and behavior</journal-title></journal-title-group><issn pub-type="ppub">1090-7165</issn><issn pub-type="epub">1573-3254</issn></journal-meta><article-meta><article-id pub-id-type="pmid">25037488</article-id><article-id pub-id-type="pmc">4198463</article-id><article-id pub-id-type="doi">10.1007/s10461-014-0849-1</article-id><article-id pub-id-type="manuscript">NIHMS614840</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Gender-specific risk factors for virologic failure in KwaZulu-Natal: Automobile ownership and financial insecurity</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>HARE</surname><given-names>Anna Q.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>ORDÓÑEZ</surname><given-names>Claudia E.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>JOHNSON</surname><given-names>Brent A.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>RIO</surname><given-names>Carlos DEL</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>KEARNS</surname><given-names>Rachel A.</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>WU</surname><given-names>Baohua</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>HAMPTON</surname><given-names>Jane</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>WU</surname><given-names>Peng</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>SUNPATH</surname><given-names>Henry</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>MARCONI</surname><given-names>Vincent C.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A7">7</xref></contrib></contrib-group><aff id="A1"><label>1</label>Emory University School of Medicine, Atlanta, Georgia, USA</aff><aff id="A2"><label>2</label>McCord Hospital, Durban, South Africa</aff><aff id="A3"><label>3</label>Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</aff><aff id="A4"><label>4</label>Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</aff><aff id="A5"><label>5</label>Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA</aff><aff id="A6"><label>6</label>Infectious Diseases Unit, Nelson Mandela School of Medicine, University of KwaZulu-Natal, KwaZulu-Natal, South Africa</aff><aff id="A7"><label>7</label>Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA</aff><author-notes><corresp id="FN1">For Correspondence and Reprints: Vincent Marconi [ <email>vcmarco@emory.edu</email> and current address:341 Ponce de Leon Avenue, Atlanta, GA, 30308, USA]</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>23</day><month>7</month><year>2014</year></pub-date><pub-date pub-type="ppub"><month>11</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>11</month><year>2015</year></pub-date><volume>18</volume><issue>11</issue><fpage>2219</fpage><lpage>2229</lpage><pmc-comment>elocation-id from pubmed: 10.1007/s10461-014-0849-1</pmc-comment>
<abstract><p id="P1">We sought to examine which socioeconomic indicators are risk factors for virologic failure among HIV-1 infected patients receiving antiretroviral therapy in KwaZulu-Natal, South Africa. A case-control study of virologic failure was conducted among patients recruited from the outpatient clinic at McCord Hospital in Durban, South Africa between October 1, 2010 and June 30, 2012. Cases were those failing first-line antiretroviral therapy (ART), defined as viral load > 1000 copies/mL. Univariate logistic regression was performed on sociodemographic data for the outcome of virologic failure. Variables found significant (p<.05) were used in multivariate models and all models were stratified by gender. Of 158 cases and 300 controls, 35% were male and median age was 40 years. Gender stratification of models revealed automobile ownership was a risk factor among males, while variables of financial insecurity (unemployment, non-spouse family paying for care, staying with family) were risk factors for women. In this cohort, financial insecurity among women and automobile ownership among men were risk factors for virologic failure. Risk factor differences between genders demonstrate limitations of generalized risk factor analysis.</p></abstract><kwd-group><kwd>HIV/AIDS</kwd><kwd>antiretroviral treatment</kwd><kwd>virologic failure</kwd><kwd>structural barriers</kwd><kwd>gender</kwd><kwd>South Africa</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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