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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Non-communicable diseases in low- and middle-income countries: context, determinants and health policy</title>
<author><name sortKey="Miranda, J J" sort="Miranda, J J" uniqKey="Miranda J" first="J. J." last="Miranda">J. J. Miranda</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kinra, S" sort="Kinra, S" uniqKey="Kinra S" first="S." last="Kinra">S. Kinra</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Casas, J P" sort="Casas, J P" uniqKey="Casas J" first="J. P." last="Casas">J. P. Casas</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Smith, G Davey" sort="Smith, G Davey" uniqKey="Smith G" first="G. Davey" last="Smith">G. Davey Smith</name>
<affiliation><nlm:aff id="A2">Department of Social Medicine, University of Bristol, Bristol, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ebrahim, S" sort="Ebrahim, S" uniqKey="Ebrahim S" first="S." last="Ebrahim">S. Ebrahim</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">18937743</idno>
<idno type="pmc">2687091</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687091</idno>
<idno type="RBID">PMC:2687091</idno>
<idno type="doi">10.1111/j.1365-3156.2008.02116.x</idno>
<date when="2008">2008</date>
<idno type="wicri:Area/Pmc/Corpus">001F08</idno>
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</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Non-communicable diseases in low- and middle-income countries: context, determinants and health policy</title>
<author><name sortKey="Miranda, J J" sort="Miranda, J J" uniqKey="Miranda J" first="J. J." last="Miranda">J. J. Miranda</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kinra, S" sort="Kinra, S" uniqKey="Kinra S" first="S." last="Kinra">S. Kinra</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Casas, J P" sort="Casas, J P" uniqKey="Casas J" first="J. P." last="Casas">J. P. Casas</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Smith, G Davey" sort="Smith, G Davey" uniqKey="Smith G" first="G. Davey" last="Smith">G. Davey Smith</name>
<affiliation><nlm:aff id="A2">Department of Social Medicine, University of Bristol, Bristol, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ebrahim, S" sort="Ebrahim, S" uniqKey="Ebrahim S" first="S." last="Ebrahim">S. Ebrahim</name>
<affiliation><nlm:aff id="A1">Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Tropical medicine & international health : TM & IH</title>
<idno type="ISSN">1360-2276</idno>
<idno type="eISSN">1365-3156</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Summary</title>
<p id="P1">The rise of non-communicable diseases and their impact in low- and middle-income countries has gained increased attention in recent years. However, the explanation for this rise is mostly an extrapolation from the history of high-income countries whose experience differed from the development processes affecting today’s low- and middle-income countries. This review appraises these differences in context to gain a better understanding of the epidemic of non-communicable diseases in low- and middle-income countries. Theories of developmental and degenerative determinants of non-communicable diseases are discussed to provide strong evidence for a causally informed approach to prevention. Health policies for non-communicable diseases are considered in terms of interventions to reduce population risk and individual susceptibility and the research needs for low- and middle-income countries are discussed. Finally, the need for health system reform to strengthen primary care is highlighted as a major policy to reduce the toll of this rising epidemic.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9610576</journal-id>
<journal-id journal-id-type="pubmed-jr-id">20323</journal-id>
<journal-id journal-id-type="nlm-ta">Trop Med Int Health</journal-id>
<journal-id journal-id-type="iso-abbrev">Trop. Med. Int. Health</journal-id>
<journal-title-group><journal-title>Tropical medicine & international health : TM & IH</journal-title>
</journal-title-group>
<issn pub-type="ppub">1360-2276</issn>
<issn pub-type="epub">1365-3156</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">18937743</article-id>
<article-id pub-id-type="pmc">2687091</article-id>
<article-id pub-id-type="doi">10.1111/j.1365-3156.2008.02116.x</article-id>
<article-id pub-id-type="manuscript">UKMS5009</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Non-communicable diseases in low- and middle-income countries: context, determinants and health policy</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Miranda</surname>
<given-names>J. J.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kinra</surname>
<given-names>S.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Casas</surname>
<given-names>J. P.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Smith</surname>
<given-names>G. Davey</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ebrahim</surname>
<given-names>S.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Non-communicable Disease Epidemiology Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</aff>
<aff id="A2"><label>2</label>
Department of Social Medicine, University of Bristol, Bristol, UK</aff>
<author-notes><corresp id="CR1"><bold>Corresponding Author</bold>
Shah Ebrahim, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St., London WC1E 7HT, UK. Tel.: +44 20 7927 2215; Fax: +44 20 7927 2282; E-mail: <email>shah.ebrahim@lshtm.ac.uk</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>18</day>
<month>5</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="ppub"><month>10</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>27</day>
<month>5</month>
<year>2009</year>
</pub-date>
<volume>13</volume>
<issue>10</issue>
<fpage>1225</fpage>
<lpage>1234</lpage>
<permissions><copyright-statement>© 2008 Blackwell Publishing Ltd</copyright-statement>
<copyright-year>2008</copyright-year>
</permissions>
<abstract><title>Summary</title>
<p id="P1">The rise of non-communicable diseases and their impact in low- and middle-income countries has gained increased attention in recent years. However, the explanation for this rise is mostly an extrapolation from the history of high-income countries whose experience differed from the development processes affecting today’s low- and middle-income countries. This review appraises these differences in context to gain a better understanding of the epidemic of non-communicable diseases in low- and middle-income countries. Theories of developmental and degenerative determinants of non-communicable diseases are discussed to provide strong evidence for a causally informed approach to prevention. Health policies for non-communicable diseases are considered in terms of interventions to reduce population risk and individual susceptibility and the research needs for low- and middle-income countries are discussed. Finally, the need for health system reform to strengthen primary care is highlighted as a major policy to reduce the toll of this rising epidemic.</p>
</abstract>
<kwd-group><kwd>chronic diseases</kwd>
<kwd>developing countries</kwd>
<kwd>epidemiology</kwd>
<kwd>health transition</kwd>
<kwd>non-communicable diseases</kwd>
<kwd>population</kwd>
<kwd>public health</kwd>
<kwd>risk factors</kwd>
<kwd>urbanisation</kwd>
<kwd>world health</kwd>
</kwd-group>
<funding-group><award-group><funding-source country="United Kingdom">Wellcome Trust : </funding-source>
<award-id>074833 || WT</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>
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